-
1
-
-
61449180271
-
Survival of patients in a Phase 1 Clinic: The M. D. Anderson Cancer Center experience
-
Wheler J, Tsimberidou AM, Hong D, Naing A, Jackson T, et al. (2009) Survival of patients in a Phase 1 Clinic: the M. D. Anderson Cancer Center experience. Cancer 115: 1091-1099.
-
(2009)
Cancer
, vol.115
, pp. 1091-1099
-
-
Wheler, J.1
Tsimberidou, A.M.2
Hong, D.3
Naing, A.4
Jackson, T.5
-
2
-
-
70349315327
-
"Sufficient life expectancy": An amazing inclusion criterion in cancer phase II-III trials
-
Penel N, Clisant S, Lefebvre JL, Adenis A (2009) "Sufficient life expectancy": an amazing inclusion criterion in cancer phase II-III trials. J Clin Oncol 27: e105.
-
(2009)
J Clin Oncol
, vol.27
-
-
Penel, N.1
Clisant, S.2
Lefebvre, J.L.3
Adenis, A.4
-
3
-
-
0141956306
-
Performance status score: Do patients and their oncologists agree?
-
DOI 10.1038/sj.bjc.6601231
-
Blagden SP, Charman SC, Sharples LD, Magee LR, Gilligan D (2003) Performance status score: do patients and their oncologists agree? Br J Cancer 89: 1022-1027. (Pubitemid 37239205)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.6
, pp. 1022-1027
-
-
Blagden, S.P.1
Charman, S.C.2
Sharples, L.D.3
Magee, L.R.A.4
Gilligan, D.5
-
4
-
-
84864062082
-
Lifeexpectancy of patients enrolled in phase 1 clinical trials: A systematic review of published prognostic models
-
Ploquin A, Olmos D, Ferte C, Cassier PA, Kramar A, et al. (2012) Lifeexpectancy of patients enrolled in phase 1 clinical trials: A systematic review of published prognostic models. Crit Rev Oncol Hematol.
-
(2012)
Crit Rev Oncol Hematol
-
-
Ploquin, A.1
Olmos, D.2
Ferte, C.3
Cassier, P.A.4
Kramar, A.5
-
5
-
-
74149089423
-
Development and validation of a model that predicts early death among cancer patients participating in phase I clinical trials investigating cytotoxics
-
Penel N, Delord JP, Bonneterre ME, Bachelot T, Ray-Coquard I, et al. (2010) Development and validation of a model that predicts early death among cancer patients participating in phase I clinical trials investigating cytotoxics. Invest New Drugs 28: 76-82.
-
(2010)
Invest New Drugs
, vol.28
, pp. 76-82
-
-
Penel, N.1
Delord, J.P.2
Bonneterre, M.E.3
Bachelot, T.4
Ray-Coquard, I.5
-
6
-
-
0033208598
-
Survival and prognostic factors in lung cancer patients treated in phase I trials: Japanese experience
-
Yamamoto N, Tamura T, Fukuoka M, Saijo N (1999) Survival and prognostic factors in lung cancer patients treated in phase I trials: Japanese experience. Int J Oncol 15: 737-741.
-
(1999)
Int J Oncol
, vol.15
, pp. 737-741
-
-
Yamamoto, N.1
Tamura, T.2
Fukuoka, M.3
Saijo, N.4
-
7
-
-
40849111655
-
Clinical outcome and prognostic factors for patients treated within the context of a phase I study: The Royal Marsden Hospital experience
-
DOI 10.1038/sj.bjc.6604218, PII 6604218
-
Arkenau HT, Olmos D, Ang JE, de Bono J, Judson I, et al. (2008) Clinical outcome and prognostic factors for patients treated within the context of a phase I study: the Royal Marsden Hospital experience. Br J Cancer 98: 1029-1033. (Pubitemid 351399798)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.6
, pp. 1029-1033
-
-
Arkenau, H.-T.1
Olmos, D.2
Ang, J.E.3
De Bono, J.4
Judson, I.5
Kaye, S.6
-
8
-
-
46049110497
-
90-Days mortality rate in patients treated within the context of a phase-I trial: How should we identify patients who should not go on trial?
-
Arkenau HT, Olmos D, Ang JE, Barriuso J, Karavasilis V, et al. (2008) 90-Days mortality rate in patients treated within the context of a phase-I trial: how should we identify patients who should not go on trial? Eur J Cancer 44: 1536-1540.
-
(2008)
Eur J Cancer
, vol.44
, pp. 1536-1540
-
-
Arkenau, H.T.1
Olmos, D.2
Ang, J.E.3
Barriuso, J.4
Karavasilis, V.5
-
9
-
-
84891851200
-
Developing an objective marker to optimize patient selection and predict survival benefit in early-phase cancer trials
-
doi: 10.1002/cncr.28381
-
Stavraka C, Pinato DJ, Turnbull SJ, Flynn MJ, Forster MD, et al. (2013) Developing an objective marker to optimize patient selection and predict survival benefit in early-phase cancer trials. Cancer doi: 10.1002/cncr.28381
-
(2013)
Cancer
-
-
Stavraka, C.1
Pinato, D.J.2
Turnbull, S.J.3
Flynn, M.J.4
Forster, M.D.5
-
10
-
-
84857039146
-
Pitfalls and limitations of a single-centre, retrospectively derived prognostic score for Phase I oncology trial participants - Reply to Fussenich et al.: A new, simple and objective prognostic score for Phase I cancer patients
-
Olmos D, Ang JE, Gomez-Roca C, Morales-Barrera R, Vulink AJ, et al. (2012) Pitfalls and limitations of a single-centre, retrospectively derived prognostic score for Phase I oncology trial participants - Reply to Fussenich et al.: A new, simple and objective prognostic score for Phase I cancer patients. Eur J Cancer 48:594-596.
-
(2012)
Eur J Cancer
, vol.48
, pp. 594-596
-
-
Olmos, D.1
Ang, J.E.2
Gomez-Roca, C.3
Morales-Barrera, R.4
Vulink, A.J.5
-
11
-
-
80053508337
-
Early mortality and overall survival in oncology phase I trial participants: Can we improve patient selection?
-
Chau NG, Florescu A, Chan KK, Wang L, Chen EX, et al. (2011) Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection? BMC Cancer 11: 426.
-
(2011)
BMC Cancer
, vol.11
, pp. 426
-
-
Chau, N.G.1
Florescu, A.2
Chan, K.K.3
Wang, L.4
Chen, E.X.5
-
12
-
-
41549095568
-
Treatment outcome and survival in participants of phase I oncology trials carried out from 2003 to 2006 at Institut Gustave Roussy
-
DOI 10.1093/annonc/mdm548
-
Italiano A, Massard C, Bahleda R, Vataire AL, Deutsch E, et al. (2008) Treatment outcome and survival in participants of phase I oncology trials carried out from 2003 to 2006 at Institut Gustave Roussy. Ann Oncol 19: 787-792. (Pubitemid 351467383)
-
(2008)
Annals of Oncology
, vol.19
, Issue.4
, pp. 787-792
-
-
Italiano, A.1
Massard, C.2
Bahleda, R.3
Vataire, A.-L.4
Deutsch, E.5
Magne, N.6
Pignon, J.-P.7
Vassal, G.8
Armand, J.-P.9
Soria, J.-C.10
-
13
-
-
33751175224
-
Barriers in phase I cancer clinical trials referrals and enrollment: Five-year experience at the Princess Margaret Hospital
-
Ho J, Pond GR, Newman C, Maclean M, Chen EX, et al. (2006) Barriers in phase I cancer clinical trials referrals and enrollment: five-year experience at the Princess Margaret Hospital. BMC Cancer 6: 263.
-
(2006)
BMC Cancer
, vol.6
, pp. 263
-
-
Ho, J.1
Pond, G.R.2
Newman, C.3
Maclean, M.4
Chen, E.X.5
-
14
-
-
3242679103
-
Phase I trial design for solid tumor studies of targeted, non-cytotoxic agents: Theory and practice
-
Parulekar WR, Eisenhauer EA (2004) Phase I trial design for solid tumor studies of targeted, non-cytotoxic agents: theory and practice. J Natl Cancer Inst 96:990-997. (Pubitemid 39162641)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.13
, pp. 990-997
-
-
Parulekar, W.R.1
Eisenhauer, E.A.2
-
15
-
-
0037180757
-
Inflammation and cancer
-
DOI 10.1038/nature01322
-
Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420: 860-867. (Pubitemid 36019639)
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
17
-
-
33644824945
-
The cancer cachexia syndrome: A review of metabolic and clinical manifestations
-
Esper DH, Harb WA (2005) The cancer cachexia syndrome: a review of metabolic and clinical manifestations. Nutr Clin Pract 20: 369-376. (Pubitemid 47050807)
-
(2005)
Nutrition in Clinical Practice
, vol.20
, Issue.4
, pp. 369-376
-
-
Esper, D.H.1
Harb, W.A.2
-
19
-
-
65549146877
-
Systemic inflammation, nutritional status and survival in patients with cancer
-
McMillan DC (2009) Systemic inflammation, nutritional status and survival in patients with cancer. Curr Opin Clin Nutr Metab Care 12: 223-226.
-
(2009)
Curr Opin Clin Nutr Metab Care
, vol.12
, pp. 223-226
-
-
McMillan, D.C.1
-
20
-
-
80755128486
-
A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study
-
Proctor MJ, Morrison DS, Talwar D, Balmer SM, Fletcher CD, et al. (2011) A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. Eur J Cancer Nov;47(17):2633-41.
-
(2011)
Eur J Cancer Nov
, vol.47
, Issue.17
, pp. 2633-2641
-
-
Proctor, M.J.1
Morrison, D.S.2
Talwar, D.3
Balmer, S.M.4
Fletcher, C.D.5
-
21
-
-
84863973568
-
An inflammation-based prognostic index predicts survival advantage after transarterial chemoembolization in hepatocellular carcinoma
-
Aug
-
Pinato DJ, Sharma R (2012) An inflammation-based prognostic index predicts survival advantage after transarterial chemoembolization in hepatocellular carcinoma. Translational Research. Aug;160(2):146-52.
-
(2012)
Translational Research
, vol.160
, Issue.2
, pp. 146-152
-
-
Pinato, D.J.1
Sharma, R.2
-
22
-
-
77955541359
-
The association of pre-treatment peripheral blood markers with survival in patients with pancreatic cancer
-
Aliustaoglu M, Bilici A, Seker M, Dane F, Gocun M, et al. (2010) The association of pre-treatment peripheral blood markers with survival in patients with pancreatic cancer. Hepatogastroenterology 57: 640-645.
-
(2010)
Hepatogastroenterology
, vol.57
, pp. 640-645
-
-
Aliustaoglu, M.1
Bilici, A.2
Seker, M.3
Dane, F.4
Gocun, M.5
-
23
-
-
78650389810
-
High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy
-
Kao SC, Pavlakis N, Harvie R, Vardy JL, Boyer MJ, et al. (2010) High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy. Clin Cancer Res 16: 5805-5813.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5805-5813
-
-
Kao, S.C.1
Pavlakis, N.2
Harvie, R.3
Vardy, J.L.4
Boyer, M.J.5
-
25
-
-
84867583029
-
A novel and validated prognostic index in hepatocellular carcinoma: The inflammation based index (IBI)
-
Pinato DJ, Stebbing J, Ishizuka M, Khan SA, Wasan HS, et al. (2012) A novel and validated prognostic index in hepatocellular carcinoma: the inflammation based index (IBI). J Hepatol 57: 1013-1020.
-
(2012)
J Hepatol
, vol.57
, pp. 1013-1020
-
-
Pinato, D.J.1
Stebbing, J.2
Ishizuka, M.3
Khan, S.A.4
Wasan, H.S.5
-
26
-
-
84857917042
-
Inflammation-based prognostic indices in malignant pleural mesothelioma
-
Pinato DJ, Mauri FA, Ramakrishnan R, Wahab L, Lloyd T, et al. (2012) Inflammation-based prognostic indices in malignant pleural mesothelioma. J Thorac Oncol 7: 587-594.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 587-594
-
-
Pinato, D.J.1
Mauri, F.A.2
Ramakrishnan, R.3
Wahab, L.4
Lloyd, T.5
-
29
-
-
84863985552
-
Systemic inflammation and prediction of chemotherapy outcomes in patients receiving docetaxel for advanced cancer
-
Chua W, Clarke SJ, Charles KA (2012) Systemic inflammation and prediction of chemotherapy outcomes in patients receiving docetaxel for advanced cancer. Support Care Cancer 20: 1869-1874.
-
(2012)
Support Care Cancer
, vol.20
, pp. 1869-1874
-
-
Chua, W.1
Clarke, S.J.2
Charles, K.A.3
-
30
-
-
79954430604
-
Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
-
Chua W, Charles KA, Baracos VE, Clarke SJ (2011) Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer. Br J Cancer 104: 1288-1295.
-
(2011)
Br J Cancer
, vol.104
, pp. 1288-1295
-
-
Chua, W.1
Charles, K.A.2
Baracos, V.E.3
Clarke, S.J.4
-
31
-
-
84884156891
-
The systemic inflammation-based neutrophil-lymphocyte ratio: Experience in patients with cancer
-
2013 Oct
-
Guthrie GJ, Charles KA, Roxburgh CS, Horgan PG, McMillan DC, et al. (2013) The systemic inflammation-based neutrophil-lymphocyte ratio: Experience in patients with cancer. Crit Rev Oncol Hematol 2013 Oct;88(1):218-30.
-
(2013)
Crit Rev Oncol Hematol
, vol.88
, Issue.1
, pp. 218-230
-
-
Guthrie, G.J.1
Charles, K.A.2
Roxburgh, C.S.3
Horgan, P.G.4
McMillan, D.C.5
-
32
-
-
84876986843
-
The systemic inflammation-based Glasgow Prognostic Score: A decade of experience in patients with cancer
-
McMillan DC (2013) The systemic inflammation-based Glasgow Prognostic Score: a decade of experience in patients with cancer. Cancer Treat Rev 39:534-540.
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 534-540
-
-
McMillan, D.C.1
-
33
-
-
67650481213
-
Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas
-
Ray-Coquard I, Cropet C, Van Glabbeke M, Sebban C, Le Cesne A, et al. (2009) Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas. Cancer Res 69: 5383-5391.
-
(2009)
Cancer Res
, vol.69
, pp. 5383-5391
-
-
Ray-Coquard, I.1
Cropet, C.2
Van Glabbeke, M.3
Sebban, C.4
Le Cesne, A.5
-
34
-
-
77954743969
-
Cancer inflammation and regulatory T cells
-
Erdman SE, Poutahidis T (2010) Cancer inflammation and regulatory T cells. Int J Cancer 127: 768-779.
-
(2010)
Int J Cancer
, vol.127
, pp. 768-779
-
-
Erdman, S.E.1
Poutahidis, T.2
-
35
-
-
38149057329
-
Prognostic factors among cancer patients with good performance status screened for phase I trials
-
Penel N, Vanseymortier M, Bonneterre ME, Clisant S, Dansin E, et al. (2008) Prognostic factors among cancer patients with good performance status screened for phase I trials. Invest New Drugs 26: 53-58.
-
(2008)
Invest New Drugs
, vol.26
, pp. 53-58
-
-
Penel, N.1
Vanseymortier, M.2
Bonneterre, M.E.3
Clisant, S.4
Dansin, E.5
-
36
-
-
61649106928
-
Inflammation and liver cancer: New molecular links
-
Berasain C, Castillo J, Perugorria MJ, Latasa MU, Prieto J, et al. (2009) Inflammation and liver cancer: new molecular links. Ann N Y Acad Sci 1155:206-221.
-
(2009)
Ann N Y Acad Sci
, vol.1155
, pp. 206-221
-
-
Berasain, C.1
Castillo, J.2
Perugorria, M.J.3
Latasa, M.U.4
Prieto, J.5
-
37
-
-
0242266499
-
Comparison of prognostic factors in patients in phase I trials of cytotoxic drugs vs new noncytotoxic agents
-
DOI 10.1038/sj.bjc.6601218
-
Han C, Braybrooke JP, Deplanque G, Taylor M, Mackintosh D, et al. (2003) Comparison of prognostic factors in patients in phase I trials of cytotoxic drugs vs new noncytotoxic agents. Br J Cancer 89: 1166-1171. (Pubitemid 37363397)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.7
, pp. 1166-1171
-
-
Han, C.1
Braybrooke, J.P.2
Deplanque, G.3
Taylor, M.4
Mackintosh, D.5
Kaur, K.6
Samouri, K.7
Ganesan, T.S.8
Harris, A.L.9
Talbot, D.C.10
-
38
-
-
79955762500
-
Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data
-
Simon RM, Subramanian J, Li MC, Menezes S (2011) Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data. Brief Bioinform 12: 203-214.
-
(2011)
Brief Bioinform
, vol.12
, pp. 203-214
-
-
Simon, R.M.1
Subramanian, J.2
Li, M.C.3
Menezes, S.4
-
39
-
-
84857055503
-
Patient selection for oncology phase I trials: A multi-institutional study of prognostic factors
-
Olmos D, A'Hern R P, Marsoni S, Morales R, Gomez-Roca C, et al. (2012) Patient selection for oncology phase I trials: a multi-institutional study of prognostic factors. J Clin Oncol 30: 996-1004.
-
(2012)
J Clin Oncol
, vol.30
, pp. 996-1004
-
-
Olmos, D.1
A'Hern, R.P.2
Marsoni, S.3
Morales, R.4
Gomez-Roca, C.5
-
40
-
-
0037194409
-
Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response
-
Rivory LP, Slaviero KA, Clarke SJ (2002) Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. Br J Cancer 87: 277-280.
-
(2002)
Br J Cancer
, vol.87
, pp. 277-280
-
-
Rivory, L.P.1
Slaviero, K.A.2
Clarke, S.J.3
-
41
-
-
0032237989
-
Impact of nutrition on pharmacokinetics of anti-neoplastic agents
-
Murry DJ, Riva L, Poplack DG (1998) Impact of nutrition on pharmacokinetics of anti-neoplastic agents. Int J Cancer Suppl 11: 48-51.
-
(1998)
Int J Cancer Suppl
, vol.11
, pp. 48-51
-
-
Murry, D.J.1
Riva, L.2
Poplack, D.G.3
-
42
-
-
42649097570
-
Identification of factors limiting patient recruitment into phase I trials: A study from the Royal Marsden Hospital
-
Karavasilis V, Digue L, Arkenau T, Eaton D, Stapleton S, et al. (2008) Identification of factors limiting patient recruitment into phase I trials: a study from the Royal Marsden Hospital. Eur J Cancer 44: 978-982.
-
(2008)
Eur J Cancer
, vol.44
, pp. 978-982
-
-
Karavasilis, V.1
Digue, L.2
Arkenau, T.3
Eaton, D.4
Stapleton, S.5
|