BML-111, a lipoxin receptor agonist, attenuates ventilator-induced lung injury in rats

Shock

Volumn 41, Issue 4, 2014, Pages 311-316

  Li, Hongbin ^a   Wu, Zhouyang ^a   Feng, Dan ^a   Gong, Jie ^a   Yao, Chengye ^a   Wang, Yaxin ^a   Yuan, Shiying ^a   Yao, Shanglong ^a   Shang, You ^a  

^a Union Hospital   (China)

Author keywords

BML 111; Inflammation; Lipoxins; MAPK; NF B; Ventilator induced lung injury

Indexed keywords

5,6,7 TRIHYDROXYHEPTANOIC ACID METHYL ESTER; ANTIINFLAMMATORY AGENT; BML 111; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 5(S),6(R)-7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER; CYTOKINE; HEPTANOIC ACID DERIVATIVE; I KAPPA B; LIPOXIN RECEPTOR; NF-KAPPAB INHIBITOR ALPHA; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXIDASE; RELA PROTEIN, RAT;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL COUNT; CONTROLLED STUDY; DRUG MECHANISM; ENZYMATIC DEGRADATION; ENZYME ACTIVATION; HISTOPATHOLOGY; HOMOGENATE; INFLAMMATION; LUNG LAVAGE; LUNG PARENCHYMA; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXYGENATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TIDAL VOLUME; TRACHEOSTOMY; TRACHEOTOMY; VENTILATOR INDUCED LUNG INJURY; AGONISTS; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; DRUG SCREENING; GENE TRANSLOCATION; GENETICS; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROCEDURES; SPRAGUE DAWLEY RAT; UPREGULATION; VENTILATOR-INDUCED LUNG INJURY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DRUG EVALUATION, PRECLINICAL; HEPTANOIC ACIDS; I-KAPPA B PROTEINS; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PEROXIDASE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LIPOXIN; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA; TRANSLOCATION, GENETIC; UP-REGULATION; VENTILATOR-INDUCED LUNG INJURY;

EID: 84897000754     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000104     Document Type: Article

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