BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats

Resuscitation

Volumn 83, Issue 7, 2012, Pages 907-912

  Gong, Jie ^a   Guo, Si ^a   Li, Hong Bin ^a   Yuan, Shi Ying ^a   Shang, You ^a   Yao, Shang Long ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Acute lung injury; Haemorrhagic shock; Lipoxin; NF B; Resolution

Indexed keywords

BML 111; BOC 2; CYTOKINE; FORMYLPEPTIDE RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; I KAPPA B ALPHA; INTERCELLULAR ADHESION MOLECULE 1; LIPOXIN RECEPTOR; MYELOPEROXIDASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ANTAGONISM; ENZYME ACTIVITY; HEMORRHAGIC SHOCK; HISTOPATHOLOGY; INFLAMMATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; RESUSCITATION;

ACUTE LUNG INJURY; ANIMALS; BLOTTING, WESTERN; CELL ADHESION MOLECULES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HEPTANOIC ACIDS; LUNG; MALE; NF-KAPPA B; OLIGOPEPTIDES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LIPOXIN; RESUSCITATION; SHOCK, HEMORRHAGIC;

EID: 84862822042     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2011.12.035     Document Type: Article

References (28)

1. Kauvar D.S., Lefering R., Wade C.E. Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations. J Trauma 2006, 60:S3-S11.
2. Keel M., Trentz O. Pathophysiology of polytrauma. Injury 2005, 36:691-709.
3. Yang C.H., Tsai P.S., Wang T.Y., Huang C.J. Dexmedetomidine-ketamine combination mitigates acute lung injury in haemorrhagic shock rats. Resuscitaion 2009, 80:1204-1210.
4. Chu H.N., Tsai P.S., Wang T.Y., Huang C.J. Platonin mitigates acute lung injury in haemorrhagic shock rats. Resuscitaion 2011, 82:97-104.
5. Clish C.B., O'Brien J.A., Gronert K., Stahl G.L., Petasis N.A., Serhan C.N. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc Natl Acad Sci USA 1999, 96:8247-8252.
6. Bannenberg G., Moussignac R.L., Gronert K., et al. Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration. Br J Pharmacol 2004, 143:43-52.
7. 4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. J Clin Invest 1999, 104:309-316.
8. 4 analog attenuates lipopolysaccharide-induced acute lung injury in mice: the role of heme oxygenase-1. Anesth Analg 2007, 104:369-377.
9. Chiang N., Fierro I.M., Gronert K., Serhan C.N. Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation. J Exp Med 2000, 191:1197-1208.
10. 4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry 1995, 34:14609-14615.
11. Forsman H., Dahlgren C. Lipoxin A(4) metabolites/analogues from two commercial sources have no effects on TNF-α-mediated priming or activation through the neutrophil formyl peptide receptors. Scand J Immunol 2009, 70:396-402.
12. 4 receptor agonist, on carbon tetrachloride-induced liver injury in mice. Hepatol Res 2007, 37:948-956.
13. Conte F.P., Menezes-de-Lima O., Verri W.A., Cunha F.Q., Penido C., Henriques M.G. Lipoxin A(4) attenuates zymosan-induced arthritis by modulating endothelin-1 and its effects. Br J Pharmacol 2010, 161:911-924.
14. Shults C., Sailhamer E.A., Liu B., et al. Surviving blood loss without fluid resuscitation. J Trauma 2008, 64:638-640.
15. Shang Y., Xu S.P., Wu Y., et al. Melatonin reduces acute lung injury in endotoxemic rats. Chin Med J 2009, 122:1388-1393.
16. Al-Amran F.G., Hadi N.R., Hashim A.M. Leukotriene biosynthesis inhibition ameliorates acute lung injury following hemorrhagic shock in rats. J Cardiothoracic Surg 2011, 6:81.
17. Shang Y., Jiang Y.X., Xu S.P., et al. Reduction of pulmonary inflammatory response by erythropoietin in a rat model of endotoxaemia. Chin Med J 2009, 122:834-838.
18. 4 methyl ester in a rat model of permanent focal cerebral ischemia. J Mol Neurosci 2010, 42:226-234.
19. 4 attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells. J Neuroinflammation 2011, 8:95.
20. Abraham E. Neutrophils and acute lung injury. Crit Care Med 2003, 31:S195-S199.
21. Olanders K., Sun Z., Borjesson A., et al. The effect of intestinal ischemia and reperfusion injury on ICAM-1 expression, endothelial barrier function, neutrophil tissue influx, and protease inhibitor levels in rats. Shock 2002, 18:86-92.
22. Zemans R.L., Colgan S.P., Downey G.P. Transepithelial migration of neutrophils mechanisms and implications for acute lung injury. Am J Respir Cell Mol Biol 2009, 40:519-535.
23. Dayal S.D., Hasko G., Lu Q., et al. Trauma/hemorrhagic shock mesenteric lymph up-regulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells. Shock 2002, 17:491-495.
24. Matsuo Y., Onodera H., Shiga Y., et al. Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat: effects of neutrophil depletion. Stroke 1994, 25:1469-1475.
25. Lawrence T., Gilroy D.W., Colville-Nash P.R., Willoughby D.A. Possible new role for NF-kappa B in the resolution of inflammation. Nat Med 2001, 7:1291-1297.
26. Gilroy D.W., Lawrence T., Perretti M., Rossi A.G. Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov 2004, 3:401-416.
27. 4 of production of interleukins induced in endothelial cells by lipopolysaccharide. Inflamm Res 2008, 57:430-437.
28. 4 analogue protects brain and reduces inflammation in a rat model of focal cerebral ischemia reperfusion. Brain Res 2010, 1323:174-183.