Acute toxicity study and effect of prolonged administration (28 days) of crude ethanolic root extract of Diospyros mespiliformis Hochst (Ebenaceae) on clinical, haematological and biochemical parameters of albino rats

Journal of Ethnopharmacology

Volumn 153, Issue 1, 2014, Pages 268-273

  Luka, J ^a   Badau, S J ^a   Mbaya, A W ^a   Gadzama, J J ^a   Kumshe, H A ^a  

^a UNIVERSITY OF MAIDUGURI   (Nigeria)

Author keywords

Diospyros mespiliformis; Extract; Haematological parameters; Metabolites; Serum enzymes; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIMALARIAL AGENT; ASPARTATE AMINOTRANSFERASE; DIOSPYROS MESPILIFORMIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; ALCOHOL;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BASOPHIL; BIOCHEMICAL PARAMETER; CONTROLLED STUDY; DIOSPYROS; DIOSPYROS MESPILIFORMIS; DRUG EFFECT; EOSINOPHIL COUNT; ERYTHROCYTE COUNT; FEMALE; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN DETERMINATION; LD 50; LEUKOCYTE DIFFERENTIAL COUNT; LYMPHOCYTE COUNT; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MONOCYTE; NEUTROPHIL COUNT; NONHUMAN; PLANT ROOT; RAT; WEIGHT CHANGE; WISTAR ALBINO GLAXO RAT; WISTAR RAT; AFRICAN MEDICINE; ANIMAL; CHEMISTRY; DOSE RESPONSE; LD50; NIGERIA; TIME; TOXICITY TESTING;

ANIMALS; DIOSPYROS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FEMALE; LETHAL DOSE 50; MALE; MEDICINE, AFRICAN TRADITIONAL; NIGERIA; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, WISTAR; TIME FACTORS; TOXICITY TESTS, ACUTE;

EID: 84896979157     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.02.033     Document Type: Article

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