In silico assessment of the metabolic capabilities of an engineered functional reversal of the β-oxidation cycle for the synthesis of longer-chain (C≥4) products

Metabolic Engineering

Volumn 23, Issue , 2014, Pages 100-115

  Cintolesi, Angela ^a   Clomburg, James M ^a   Gonzalez, Ramon ^a  

^a Rice University   (United States)

Author keywords

Fuels and chemicals; In silico analysis; Systems biology; Oxidation reversal

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CHAINS; ENZYMES; ESCHERICHIA COLI; FATTY ACIDS; METABOLISM; MOLECULES;

FATTY ACID BIOSYNTHESIS; FLUX BALANCE ANALYSIS; FLUX VARIABILITY ANALYSIS; FUNCTIONALIZED COMPOUNDS; IN-SILICO; METABOLIC CAPABILITIES; PENTOSE PHOSPHATE PATHWAY; SYSTEMS BIOLOGY;

OXIDATION;

ACYL COENZYME A; ALKANE; CARBOXYLIC ACID; FATTY ACID; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; THIOESTER;

ALCOHOL PRODUCTION; ANALYTIC METHOD; ARTICLE; CELL GROWTH; CELL TRANSPORT; COMPUTER MODEL; COST EFFECTIVENESS ANALYSIS; ESCHERICHIA COLI; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; FERMENTATION; FLUX BALANCE ANALYSIS; FLUX VARIABILITY ANALYSIS; GENETIC MODEL; GLUCOSE INTAKE; GLUCOSE UTILIZATION; GROWTH RATE; METABOLIC CAPACITY; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIMULATION; SYNTHESIS; BIOLOGICAL MODEL; BIOSYNTHESIS; COMPUTER SIMULATION; GENETICS; LIPID METABOLISM; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

COMPUTER SIMULATION; ESCHERICHIA COLI; FATTY ACIDS; LIPID METABOLISM; MODELS, BIOLOGICAL; OXIDATION-REDUCTION;

EID: 84896979155     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.02.011     Document Type: Article

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