메뉴 건너뛰기




Volumn 4, Issue 3, 2014, Pages 411-423

Metabolic and environmental conditions determine nuclear genomic instability in budding yeast lacking mitochondrial DNA

Author keywords

Calorie restriction; DNA; Instability; Membrane; Metabolism; Mitochondrial; Nuclear genome; Potential

Indexed keywords

ALCOHOL; GLUCOSE; MITOCHONDRIAL DNA; TIRON;

EID: 84896975480     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.113.010108     Document Type: Article
Times cited : (22)

References (54)
  • 2
    • 77949318560 scopus 로고    scopus 로고
    • Metabolic reprogramming, caloric restriction and aging
    • Anderson R.M., and R. Weindruch, 2010 Metabolic reprogramming, caloric restriction and aging. Trends Endocrinol. Metab. 21: 134- 141.
    • (2010) Trends Endocrinol. Metab. , vol.21 , pp. 134-141
    • Anderson, R.M.1    Weindruch, R.2
  • 3
    • 0026008425 scopus 로고
    • Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria
    • Baker K.P., and G. Schatz, 1991 Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria. Nature 349: 205- 208.
    • (1991) Nature , vol.349 , pp. 205-208
    • Baker, K.P.1    Schatz, G.2
  • 4
    • 0002984515 scopus 로고
    • Induction of petite mutation and inhibition of synthesis of respiratory enzymes in various yeasts
    • Bulder C.J., 1964 Induction of petite mutation and inhibition of synthesis of respiratory enzymes in various yeasts. Antonie van Leeuwenhoek 30: 1-9.
    • (1964) Antonie van Leeuwenhoek , vol.30 , pp. 1-9
    • Bulder, C.J.1
  • 5
    • 0030728737 scopus 로고    scopus 로고
    • Diminished tumorigenic phenotype after depletion of mitochondrial DNA
    • Cavalli L.R., M. Varella-Garcia, and B. C. Liang, 1997 Diminished tumorigenic phenotype after depletion of mitochondrial DNA. Cell Growth Differ. 8: 1189-1198.
    • (1997) Cell Growth Differ. , vol.8 , pp. 1189-1198
    • Cavalli, L.R.1    Varella-Garcia, M.2    Liang, B.C.3
  • 6
    • 0028072911 scopus 로고
    • Thioredoxin-dependent peroxide reductase from yeast
    • Chae H.Z., Chung S.J., and S. G. Rhee, 1994 Thioredoxin-dependent peroxide reductase from yeast. J. Biol. Chem. 269: 27670-27678.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27670-27678
    • Chae, H.Z.1    Chung, S.J.2    Rhee, S.G.3
  • 7
    • 0032860479 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
    • Chen, C., and R. D. Kolodner, 1999 Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat. Genet. 23: 81-85.
    • (1999) Nat. Genet. , vol.23 , pp. 81-85
    • Chen, C.1    Kolodner, R.D.2
  • 8
    • 0032849910 scopus 로고    scopus 로고
    • The petite mutation in yeasts: 50 years on
    • Chen X.J., and G. D. Clark-Walker, 2000 The petite mutation in yeasts: 50 years on. Int. Rev. Cytol. 194: 197-238.
    • (2000) Int. Rev. Cytol. , vol.194 , pp. 197-238
    • Chen, X.J.1    Clark-Walker, G.D.2
  • 9
    • 0034122608 scopus 로고    scopus 로고
    • Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast
    • Contamine, V., and M. Picard, 2000 Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast. Microbiol. Mol. Biol. Rev. 64: 281-315.
    • (2000) Microbiol. Mol. Biol. Rev. , vol.64 , pp. 281-315
    • Contamine, V.1    Picard, M.2
  • 10
    • 84866372675 scopus 로고    scopus 로고
    • Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression
    • Crider D.G., Garcia L.J.-Rodriguez, Srivastava P., L. Peraza-Reyes, K. Upadhyaya et al., 2012 Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression. J. Cell Biol. 198: 793-798.
    • (2012) J. Cell Biol. , vol.198 , pp. 793-798
    • Crider, D.G.1    Garcia L.J.-Rodriguez Srivastava, P.2    Peraza-Reyes, L.3    Upadhyaya, K.4
  • 11
    • 0030974313 scopus 로고    scopus 로고
    • Marker swap plasmids: convenient tools for budding yeast molecular genetics
    • Cross F.R., 1997 "Marker swap" plasmids: convenient tools for budding yeast molecular genetics. Yeast 13: 647-653.
    • (1997) Yeast , vol.13 , pp. 647-653
    • Cross, F.R.1
  • 12
    • 0345328791 scopus 로고    scopus 로고
    • Mitochondrial impairment is accompanied by impaired oxidative DNA repair in the nucleus
    • Delsite R.L., Rasmussen L.J., Rasmussen A.K., Kalen A., Goswami P.C. et al., 2003 Mitochondrial impairment is accompanied by impaired oxidative DNA repair in the nucleus. Mutagenesis 18: 497-503.
    • (2003) Mutagenesis , vol.18 , pp. 497-503
    • Delsite, R.L.1    Rasmussen, L.J.2    Rasmussen, A.K.3    Kalen, A.4    Goswami, P.C.5
  • 13
    • 0036788329 scopus 로고    scopus 로고
    • Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice
    • Demeilliers, C., Maisonneuve C., A. Grodet, Mansouri A., R. Nguyen et al., 2002 Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice. Gastroenterology 123: 1278-1290.
    • (2002) Gastroenterology , vol.123 , pp. 1278-1290
    • Demeilliers, C.1    Maisonneuve, C.2    Grodet, A.3    Mansouri, A.4    Nguyen, R.5
  • 14
    • 30044444717 scopus 로고    scopus 로고
    • A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex
    • Dunn C.D., Lee M.S., Spencer F.A., and R. E. Jensen, 2006 A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol. Biol. Cell 17: 213-226.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 213-226
    • Dunn, C.D.1    Lee, M.S.2    Spencer, F.A.3    Jensen, R.E.4
  • 15
    • 0017171254 scopus 로고
    • Mutator activity of petite strains of Saccharomyces cerevisiae
    • Flury, F., von R.C. Borstel, and D. H. Williamson, 1976 Mutator activity of petite strains of Saccharomyces cerevisiae. Genetics 83: 645-653.
    • (1976) Genetics , vol.83 , pp. 645-653
    • Flury, F.1    von, R.C.2    Borstel Williamson, D.H.3
  • 16
    • 64549083295 scopus 로고    scopus 로고
    • The scientific basis of caloric restriction leading to longer life
    • Fontana, L., 2009 The scientific basis of caloric restriction leading to longer life. Curr. Opin. Gastroenterol. 25: 144-150.
    • (2009) Curr. Opin. Gastroenterol. , vol.25 , pp. 144-150
    • Fontana, L.1
  • 17
    • 84863769552 scopus 로고    scopus 로고
    • MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism
    • Gari, K., Leon A.M. Ortiz, Borel V., H. Flynn, Skehel J.M. et al., 2012 MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism. Science 337: 243-245.
    • (2012) Science , vol.337 , pp. 243-245
    • Gari, K.1    Leon, A.M.2    Ortiz Borel, V.3    Flynn, H.4    Skehel, J.M.5
  • 18
    • 84877098900 scopus 로고    scopus 로고
    • Defects associated with mitochondrial DNA damage can be mitigated by increased vacuolar pH in Saccharomyces cerevisiae
    • Garipler, G., and C. D. Dunn, 2013 Defects associated with mitochondrial DNA damage can be mitigated by increased vacuolar pH in Saccharomyces cerevisiae. Genetics 194: 285-290.
    • (2013) Genetics , vol.194 , pp. 285-290
    • Garipler, G.1    Dunn, C.D.2
  • 19
    • 0030990662 scopus 로고    scopus 로고
    • The absence of the mitochondrial ATP synthase delta subunit promotes a slow growth phenotype of rho- yeast cells by a lack of assembly of the catalytic sector F1
    • Giraud M.F., and J. Velours, 1997 The absence of the mitochondrial ATP synthase delta subunit promotes a slow growth phenotype of rho- yeast cells by a lack of assembly of the catalytic sector F1. Eur. J. Biochem. 245: 813-818.
    • (1997) Eur. J. Biochem. , vol.245 , pp. 813-818
    • Giraud, M.F.1    Velours, J.2
  • 20
    • 0030739963 scopus 로고    scopus 로고
    • Mitochondrial function is required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae
    • Grant C.M., MacIver F.H., and I. W. Dawes, 1997 Mitochondrial function is required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae. FEBS Lett. 410: 219-222.
    • (1997) FEBS Lett. , vol.410 , pp. 219-222
    • Grant, C.M.1    MacIver, F.H.2    Dawes, I.W.3
  • 21
    • 66349117823 scopus 로고    scopus 로고
    • Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis
    • Hall B.M., Ma C.X., Liang P., and K. K. Singh, 2009 Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis. Bioinformatics 25: 1564- 1565.
    • (2009) Bioinformatics , vol.25 , pp. 1564-1565
    • Hall, B.M.1    Ma, C.X.2    Liang, P.3    Singh, K.K.4
  • 22
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan, D., and R. A. Weinberg, 2011 Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 23
    • 0032565523 scopus 로고    scopus 로고
    • Genomic instability: environmental invasion and the enemies within
    • Hanawalt P.C., 1998 Genomic instability: environmental invasion and the enemies within. Mutat. Res. 400: 117-125.
    • (1998) Mutat. Res. , vol.400 , pp. 117-125
    • Hanawalt, P.C.1
  • 24
  • 25
    • 84871011474 scopus 로고    scopus 로고
    • An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast
    • Hughes A.L., and D. E. Gottschling, 2012 An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature 492: 261- 265.
    • (2012) Nature , vol.492 , pp. 261-265
    • Hughes, A.L.1    Gottschling, D.E.2
  • 26
    • 0031024637 scopus 로고    scopus 로고
    • Mitochondrial DNA loss caused by ethanol in Saccharomyces flor yeasts
    • Ibeas J.I., and J. Jimenez, 1997 Mitochondrial DNA loss caused by ethanol in Saccharomyces flor yeasts. Appl. Environ. Microbiol. 63: 7-12.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 7-12
    • Ibeas, J.I.1    Jimenez, J.2
  • 27
    • 67651202633 scopus 로고    scopus 로고
    • Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae
    • Iraqui, I., Kienda G., J. Soeur, Faye G., G. Baldacci et al., 2009 Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae. PLoS Genet. 5: e1000524.
    • (2009) PLoS Genet. , vol.5
    • Iraqui, I.1    Kienda, G.2    Soeur, J.3    Faye, G.4    Baldacci, G.5
  • 28
    • 10044264264 scopus 로고    scopus 로고
    • Impact of mitochondria on nuclear genome stability
    • Karthikeyan, G., and M. A. Resnick, 2005 Impact of mitochondria on nuclear genome stability. DNA Repair (Amst.) 4: 141-148.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 141-148
    • Karthikeyan, G.1    Resnick, M.A.2
  • 29
    • 0037341660 scopus 로고    scopus 로고
    • F1-catalysed ATP hydrolysis is required for mitochondrial biogenesis in Saccharomyces cerevisiae growing under conditions where it cannot respire
    • Lefebvre-Legendre, L., Balguerie A., S. Duvezin-Caubet, Giraud M.F., Slonimski P.P. et al., 2003 F1-catalysed ATP hydrolysis is required for mitochondrial biogenesis in Saccharomyces cerevisiae growing under conditions where it cannot respire. Mol. Microbiol. 47: 1329-1339.
    • (2003) Mol. Microbiol. , vol.47 , pp. 1329-1339
    • Lefebvre-Legendre, L.1    Balguerie, A.2    Duvezin-Caubet, S.3    Giraud, M.F.4    Slonimski, P.P.5
  • 30
    • 47249094614 scopus 로고    scopus 로고
    • Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases
    • Lill, R., and U. Muhlenhoff, 2008 Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases. Annu. Rev. Biochem. 77: 669-700.
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 669-700
    • Lill, R.1    Muhlenhoff, U.2
  • 31
    • 0035902544 scopus 로고    scopus 로고
    • Rad52 forms DNA repair and recombination centers during S phase
    • Lisby, M., Rothstein R., and U. H. Mortensen, 2001 Rad52 forms DNA repair and recombination centers during S phase. Proc. Natl. Acad. Sci. USA 98: 8276-8282.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8276-8282
    • Lisby, M.1    Rothstein, R.2    Mortensen, U.H.3
  • 32
    • 75249094454 scopus 로고    scopus 로고
    • Calorie restriction and cancer prevention: metabolic and molecular mechanisms
    • Longo V.D., and L. Fontana, 2010 Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol. Sci. 31: 89-98.
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 89-98
    • Longo, V.D.1    Fontana, L.2
  • 33
    • 0034913895 scopus 로고    scopus 로고
    • Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants
    • Mansouri, A., Demeilliers C., S. Amsellem, Pessayre D., and B. Fromenty, 2001 Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants. J. Pharmacol. Exp. Ther. 298: 737-743.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 737-743
    • Mansouri, A.1    Demeilliers, C.2    Amsellem, S.3    Pessayre, D.4    Fromenty, B.5
  • 34
    • 69949085788 scopus 로고    scopus 로고
    • Genome instability, cancer and aging
    • Maslov A.Y., and J. Vijg, 2009 Genome instability, cancer and aging. Biochim. Biophys. Acta 1790: 963-969.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 963-969
    • Maslov, A.Y.1    Vijg, J.2
  • 35
    • 0033567461 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae colony growth and ageing: biphasic growth accompanied by changes in gene expression
    • Meunier J.R., and M. Choder, 1999 Saccharomyces cerevisiae colony growth and ageing: biphasic growth accompanied by changes in gene expression. Yeast 15: 1159-1169.
    • (1999) Yeast , vol.15 , pp. 1159-1169
    • Meunier, J.R.1    Choder, M.2
  • 36
    • 0028107856 scopus 로고
    • Tumor-forming ability in athymic nude mice of human cell lines devoid of mitochondrial DNA
    • Morais, R., K. Zinkewich-Peotti, Parent M., H. Wang, F. Babai et al., 1994 Tumor-forming ability in athymic nude mice of human cell lines devoid of mitochondrial DNA. Cancer Res. 54: 3889-3896.
    • (1994) Cancer Res. , vol.54 , pp. 3889-3896
    • Morais, R.1    Zinkewich-Peotti, K.2    Parent, M.3    Wang, H.4    Babai, F.5
  • 38
    • 65549124110 scopus 로고    scopus 로고
    • Superoxide dismutase 1-mediated production of ethanol- and DNA-derived radicals in yeasts challenged with hydrogen peroxide: molecular insights into the genome instability of peroxiredoxin-null strains
    • Ogusucu, R., Rettori D., Netto L.E., and O. Augusto, 2009 Superoxide dismutase 1-mediated production of ethanol- and DNA-derived radicals in yeasts challenged with hydrogen peroxide: molecular insights into the genome instability of peroxiredoxin-null strains. J. Biol. Chem. 284: 5546-5556.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5546-5556
    • Ogusucu, R.1    Rettori, D.2    Netto, L.E.3    Augusto, O.4
  • 39
    • 33746865230 scopus 로고    scopus 로고
    • Life within a community: benefit to yeast long-term survival
    • Palkova, Z., and L. Vachova, 2006 Life within a community: benefit to yeast long-term survival. FEMS Microbiol. Rev. 30: 806-824.
    • (2006) FEMS Microbiol. Rev. , vol.30 , pp. 806-824
    • Palkova, Z.1    Vachova, L.2
  • 40
    • 34547459934 scopus 로고    scopus 로고
    • Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death
    • Ragu, S., Faye G., I. Iraqui, A. Masurel-Heneman, Kolodner R.D. et al., 2007 Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death. Proc. Natl. Acad. Sci. USA 104: 9747-9752.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 9747-9752
    • Ragu, S.1    Faye, G.2    Iraqui, I.3    Masurel-Heneman, A.4    Kolodner, R.D.5
  • 41
    • 0032493625 scopus 로고    scopus 로고
    • Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae
    • Rapaport, D., Brunner M., W. Neupert, and B. Westermann, 1998 Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae. J. Biol. Chem. 273: 20150-20155.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20150-20155
    • Rapaport, D.1    Brunner, M.2    Neupert, W.3    Westermann, B.4
  • 42
    • 0242380642 scopus 로고    scopus 로고
    • Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae
    • Rasmussen A.K., Chatterjee A., Rasmussen L.J., and K. K. Singh, 2003 Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae. Nucleic Acids Res. 31: 3909-3917.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3909-3917
    • Rasmussen, A.K.1    Chatterjee, A.2    Rasmussen, L.J.3    Singh, K.K.4
  • 43
    • 33745209199 scopus 로고    scopus 로고
    • Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae
    • Schmidt K.H., Pennaneach V., Putnam C.D., and R. D. Kolodner, 2006 Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae. Methods Enzymol. 409: 462-476.
    • (2006) Methods Enzymol. , vol.409 , pp. 462-476
    • Schmidt, K.H.1    Pennaneach, V.2    Putnam, C.D.3    Kolodner, R.D.4
  • 45
    • 0026658124 scopus 로고
    • Mitochondrial DNA damage by anticancer agents
    • Singh, G., Sharkey S.M., and R. Moorehead, 1992 Mitochondrial DNA damage by anticancer agents. Pharmacol. Ther. 54: 217-230.
    • (1992) Pharmacol. Ther. , vol.54 , pp. 217-230
    • Singh, G.1    Sharkey, S.M.2    Moorehead, R.3
  • 46
    • 0014415120 scopus 로고
    • Ethidium bromide induced mutation of yeast mitochondria: complete transformation of cells into respiratory deficient non-chromosomal "petites"
    • Slonimski P.P., Perrodin G., and J. H. Croft, 1968 Ethidium bromide induced mutation of yeast mitochondria: complete transformation of cells into respiratory deficient non-chromosomal "petites". Biochem. Biophys. Res. Commun. 30: 232-239.
    • (1968) Biochem. Biophys. Res. Commun. , vol.30 , pp. 232-239
    • Slonimski, P.P.1    Perrodin, G.2    Croft, J.H.3
  • 47
    • 84863747679 scopus 로고    scopus 로고
    • MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity
    • Stehling, O., Vashisht A.A., Mascarenhas J., Jonsson Z.O., T. Sharma et al., 2012 MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Science 337: 195-199.
    • (2012) Science , vol.337 , pp. 195-199
    • Stehling, O.1    Vashisht, A.A.2    Mascarenhas, J.3    Jonsson, Z.O.4    Sharma, T.5
  • 48
    • 57049122349 scopus 로고    scopus 로고
    • Mechanism of tiron as scavenger of superoxide ions and free electrons
    • Taiwo F.A., 2008 Mechanism of tiron as scavenger of superoxide ions and free electrons. Spectroscopy 22: 491-498.
    • (2008) Spectroscopy , vol.22 , pp. 491-498
    • Taiwo, F.A.1
  • 49
    • 84871563271 scopus 로고    scopus 로고
    • The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly
    • van Wietmarschen, N., Moradian A., Morin G.B., Lansdorp P.M., and E. J. Uringa, 2012 The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly. J. Biol. Chem. 287: 43351-43358.
    • (2012) J. Biol. Chem. , vol.287 , pp. 43351-43358
    • van Wietmarschen, N.1    Moradian, A.2    Morin, G.B.3    Lansdorp, P.M.4    Uringa, E.J.5
  • 50
    • 67549136242 scopus 로고    scopus 로고
    • Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect
    • Veatch J.R., McMurray M.A., Nelson Z.W., and D. E. Gottschling, 2009 Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell 137: 1247-1258.
    • (2009) Cell , vol.137 , pp. 1247-1258
    • Veatch, J.R.1    McMurray, M.A.2    Nelson, Z.W.3    Gottschling, D.E.4
  • 51
    • 84866665390 scopus 로고    scopus 로고
    • Mitochondria and cancer
    • Wallace D.C., 2012 Mitochondria and cancer. Nat. Rev. Cancer 12: 685-698.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 685-698
    • Wallace, D.C.1
  • 52
    • 84896901390 scopus 로고    scopus 로고
    • Temperature relations, in The Yeasts, edited by H. J. Rose. Academic Press, London.
    • Watson, K., 1987 Temperature relations, pp. 41-71 in The Yeasts, edited by H. J. Rose. Academic Press, London.
    • Watson, K.1
  • 53
    • 0030825723 scopus 로고    scopus 로고
    • Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homologue.
    • Wilson R.B., and D. M. Roof, 1997 Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homologue. Nat. Genet. 16:352-357.
    • (1997) Nat. Genet. , vol.16 , pp. 352-357
    • Wilson, R.B.1    Roof, D.M.2
  • 54
    • 4243607831 scopus 로고
    • Toxicity of iron and hydrogen peroxide: the Fenton reaction.
    • Winterbourn C.C., 1995 Toxicity of iron and hydrogen peroxide: the Fenton reaction. Toxicol. Lett. 82-83: 969-974.
    • (1995) Toxicol. Lett. , Issue.82-83 , pp. 969-974
    • Winterbourn, C.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.