What do we know about metabolic syndrome in adolescents with PCOS?

Journal of the Turkish German Gynecology Association

Volumn 15, Issue 1, 2014, Pages 49-55

  Cirik, Derya Akdaǧ ^a   Dilbaz, Berna ^a  

^a Clinic of Reproductive Endocrinology and Infertility Ankara Etlik Zübeyde Han m Women s Health Education and Research Hospital   (Turkey)

Author keywords

Adolescent; Metabolic syndrome; Polycystic ovary syndrome

Indexed keywords

ANDROGEN; CYTOKINE; METFORMIN; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; ADOLESCENT; ANOVULATION; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL FEATURE; CONSENSUS; CYTOKINE RELEASE; DIABETES MELLITUS; DIAGNOSTIC TEST; DISEASE ASSOCIATION; DISEASE MARKER; EARLY DIAGNOSIS; EXERCISE; FRUIT; HIGH RISK PATIENT; HUMAN; HYPERANDROGENISM; INCIDENCE; INSULIN RESISTANCE; LIFESTYLE MODIFICATION; LOW CARBOHYDRATE DIET; LOW FAT DIET; MEDITERRANEAN DIET; MENSTRUATION DISORDER; METABOLIC SYNDROME X; OBESITY; ONSET AGE; OVARY POLYCYSTIC DISEASE; PATHOGENESIS; PHYSICAL DISEASE; PRACTICE GUIDELINE; PREDICTION; PREVALENCE; PUBERTY; PUBLIC HEALTH PROBLEM; RISK ASSESSMENT; RISK REDUCTION; SMOKING CESSATION; SOCIOECONOMICS; SYMPTOM; TRIACYLGLYCEROL BLOOD LEVEL; VEGETABLE; WAIST CIRCUMFERENCE;

EID: 84896944705     PISSN: 13090399     EISSN: 13090380     Source Type: Journal    
DOI: 10.5152/jtgga.2014.95776     Document Type: Article

References (57)

1. Stein IF. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol 1935; 29: 181.
2. Dilbaz B, Ozkaya E, Cinar M, Cakir E, Dilbaz S. Cardiovascular disease risk characteristics of the main polycystic ovary syndrome phenotypes. Endocrine 2011; 39: 272-7. [CrossRef]
3. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 2009; 91: 456-88. [CrossRef]
4. Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, Welt CK. Diagnosis and treatment of polycystic ovary syndrome: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2013; 98: 4565-92. [CrossRef]
5. Carmina E, Oberfield SE, Lobo RA. The diagnosis of polycystic ovary syndrome in adolescents. Am J Obstet Gynecol 2010; 203: 201.e1-5.
6. Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic ovary syndrome. Lancet 2007; 370: 685-97. [CrossRef]
7. Bonny AE, Appelbaum H, Connor EL, Cromer B, DiVasta A, Gomez-Lobo V, et al. Clinical variability in approaches to polycystic ovary syndrome. J Pediatr Adolesc Gynecol 2012; 25: 259-61. [CrossRef]
8. Hardy TSE, Norman RJ. Diagnosis of adolescent polycystic ovary syndrome. Steroids. 2013; 78: 751-4. [CrossRef]
9. Yildiz BO, Bozdag G, Yapici Z, Esinler I, Yarali H. Prevalence, phenotype and cardiometabolic risk of polycystic ovary syndrome under different diagnostic criteria. Hum Reprod 2012; 27: 3067-73. [CrossRef]
10. Xita N, Tsatsoulis A. Review: fetal programming of polycystic ovary syndrome by androgen excess: evidence from experimental, clinical, and genetic association studies. J Clin Endocrinol Metab 2006; 91: 1660-6. [CrossRef]
11. Franks S, McCarthy MI, Hardy K. Development of polycystic ovary syndrome: involvement of genetic and environmental factors. Int J Androl 2006; 29: 278-85. [CrossRef]
12. Abbott DH, Dumesic DA, Franks S. Developmental origin of polycystic ovary syndrome - a hypothesis. J Endocrinol 2002; 174: 1-5. [CrossRef]
13. Barbieri RL, Hornstein MD. Hyperinsulinemia and ovarian hyperandrogenism. Cause and effect. Endocrinol Metab Clin North Am 1988; 17: 685-703.
14. Omar HA, Logsdon S, Richards J. Clinical profiles, occurrence, and management of adolescent patients with HAIR-AN syndrome. Scientific World Journal 2004; 4: 507-11. [CrossRef]
15. Kaltsas GA, Mukherjee JJ, Jenkins PJ, Satta MA, Islam N, Monson JP, et al. Menstrual irregularity in women with acromegaly. J Clin Endocrinol Metab 1999; 84: 2731-5. [CrossRef]
16. Battaglia C, Regnani G, Mancini F, Iughetti L, Flamigni C, Venturoli S. Polycystic ovaries in childhood: a common finding in daughters of PCOS patients. A pilot study. Hum Reprod 2002; 17: 771-6. [CrossRef]
17. Leibel NI, Baumann EE, Kocherginsky M, Rosenfield RL. Relationship of adolescent polycystic ovary syndrome to parental metabolic syndrome. J Clin Endocrinol Metab 2006; 91: 1275-83. [CrossRef]
18. Pugeat M. Genetics of the polycystic ovarian syndrome and therapeutic perspectives. Rev Med Chir Soc Med Nat Iasi 2000; 104: 11-9.
19. Ehrmann DA, Tang X, Yoshiuchi I, Cox NJ, Bell GI. Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab 2002; 87: 4297-300. [CrossRef]
20. Wild RA, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, et al. Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J Clin Endocrinol Metab 2010; 95: 2038-49. [CrossRef]
21. Mosca L. Guidelines for prevention of cardiovascular disease in women: a summary of recommendations. Prev Cardiol 2007; 10: 19-25. [CrossRef]
22. Teede H, Ng S, Hedger M, Moran L. Follistatin and activins in polycystic ovary syndrome: relationship to metabolic and hormonal markers. Metabolism 2013; 62: 1394-400. [CrossRef]
23. Knight PG, Satchell L, Glister C. Intra-ovarian roles of activins and inhibins. Mol Cell Endocrinol 2012; 359: 53-65. [CrossRef]
24. Sjöholm A, Nyström T. Inflammation and the etiology of type 2 diabetes. Diabetes Metab Res Rev 2006; 22: 4-10. [CrossRef]
25. Fasshauer M, Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia. 2003; 46: 1594-603. [CrossRef]
26. Pöykkö SM, Kellokoski E, Hörkkö S, Kauma H, Kesäniemi YA, Ukkola O. Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes. Diabetes 2003; 52: 2546-53. [CrossRef]
27. Glintborg D, Andersen M, Hagen C, Frystyk J, Hulstrøm V, Flyvbjerg A, Hermann AP. Evaluation of metabolic risk markers in polycystic ovary syndrome (PCOS). Adiponectin, ghrelin, leptin and body composition in hirsute PCOS patients and controls. Eur J Endocrinol 2006; 155: 337-45. [CrossRef]
28. Panidis D, Farmakiotis D, Koliakos G, Rousso D, Kourtis A, Katsikis I, et al. Comparative study of plasma ghrelin levels in women with polycystic ovary syndrome, in hyperandrogenic women and in normal controls. Hum Reprod 2005; 20: 2127-32. [CrossRef]
29. Ersan F, Arslan E, Çorbacioǧlu Esmer A, Aydin S, Gedikbaşi A, Gedikbaşi A, Alkiş I, Ark C. Prediction of metabolic syndrome in women with polycystic ovary syndrome. J Turk Ger Gynecol Assoc 2012; 13: 178-183. [CrossRef]
30. Kale-Gurbuz T, Akhan SE, Bastu E, Telci A, Iyibozkurt AC, Topuz S. Adiponectin, leptin and ghrelin levels in obese adolescent girls with polycystic ovary syndrome. J Pediatr Adolesc Gynecol 2013; 26: 27-30. [CrossRef]
31. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607. [CrossRef]
32. Zimmet P, Alberti KG, Kaufman F, Tajima N, Silink M, Arslanian S, et al. The metabolic syndrome in children and adolescents - an IDF consensus report. Pediatr Diabetes 2007; 8: 299-306. [CrossRef]
33. Çali{dorless}şkan E, Ki{dorless}li{dorless}ç T, Bodur H, Zeteroǧlu Ş. The frequency of metabolic syndrome in women with polycystic ovaries at reproductive ages and comparison of different metabolic syndrome diagnostic criteria. J Turk Ger Gynecol Assoc 2007; 8: 402-7.
34. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002; 287: 356-9. [CrossRef]
35. Carmina E, Napoli N, Longo RA, Rini GB, Lobo RA. Metabolic syndrome in polycystic ovary syndrome (PCOS): lower prevalence in southern Italy than in the USA and the influence of criteria for the diagnosis of PCOS. Eur J Endocrinol 2006; 154: 141-5. [CrossRef]
36. Goodman E, Daniels SR, Meigs JB, Dolan LM. Instability in the diag Jnosis of metabolic syndrome in adolescents. Circulation 2007; 115: 2316-22. [CrossRef]
37. Jolliffe CJ, Janssen I. Development of age-specific adolescent metabolic syndrome criteria that are linked to the Adult Treatment Panel III and International Diabetes Federation criteria. J Am Coll Cardiol 2007; 49: 891-8. [CrossRef]
38. Rahmanpour H, Jamal L, Mousavinasab SN, Esmailzadeh A, Azarkhish K. Association between polycystic ovarian syndrome, overweight, and metabolic syndrome in adolescents. J Pediatr Adolesc Gynecol 2012; 25: 208-12. [CrossRef]
39. Morrison JA, Friedman LA, Harlan WR, Harlan LC, Barton BA, Schreiber GB, Klein DJ. Development of the metabolic syndrome in black and white adolescent girls: a longitudinal assessment. Pediatrics 2005; 116: 1178-82. [CrossRef]
40. Morrison JA, Friedman LA, Gray-McGuire C. Metabolic syndrome in childhood predicts adult cardiovascular disease 25 years later: the Princeton Lipid Research Clinics Follow-up Study. Pediatrics 2007; 120: 340-5. [CrossRef]
41. Kirchengast S, Huber J. Body composition characteristics and body fat distribution in lean women with polycystic ovary syndrome. Hum Reprod 2001; 16: 1255-60. [CrossRef]
42. Roe AH, Prochaska E, Smith M, Sammel M, Dokras A. Using the androgen excess-PCOS society criteria to diagnose polycystic ovary syndrome and the risk of metabolic syndrome in adolescents. J Pediatr 2013; 162: 937-41. [CrossRef]
43. Hart R, Doherty DA, Mori T, Huang RC, Norman RJ, Franks S, et al. Extent of metabolic risk in adolescent girls with features of polycystic ovary syndrome. Fertil Steril 2011; 95: 2347-53. [CrossRef]
44. Wijeyaratne CN, Seneviratne Rde A, Dahanayake S, Kumarapeli V, Palipane E, Kuruppu N, et al. Phenotype and metabolic profile of South Asian women with polycystic ovary syndrome (PCOS): results of a large database from a specialist Endocrine Clinic. Hum Reprod 2011; 26: 202-13. [CrossRef]
45. Amato MC, Guarnotta V, Forti D, Donatelli M, Dolcimascolo S, Giordano C. Metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy polycystic ovary syndrome (MU-PCOS): a comparative analysis of four simple methods useful for metabolic assessment. Human Reprod 2013; 28: 1919-28. [CrossRef]
46. Rossi B, Sukalich S, Droz J, Griffin A, Cook S, Blumkin A, et al. Prevalence of metabolic syndrome and related characteristics in obese adolescents with and without polycystic ovary syndrome. J Clin Endocrinol Metab 2008; 93: 4780-6. [CrossRef]
47. Lerchbaum E, Schwetz V, Giuliani A, Obermayer-Pietsch B. Assessment of glucose metabolism in polycystic ovary syndrome: HbA1c or fasting glucose compared with the oral glucose tolerance test as a screening method. Hum Reprod 2013; 28: 2537-44. [CrossRef]
48. Ornstein RM, Copperman NM, Jacobson MS. Effect of weight loss on menstrual function in adolescents with polycystic ovary syndrome. J Pediatr Adolesc Gynecol 2011; 24: 161-5. [CrossRef]
49. Marsh KA, Steinbeck KS, Atkinson FS, Petocz P, Brand-Miller JC. Effect of a low glycemic index compared with a conventional healthy diet on polycystic ovary syndrome. Am J Clin Nutr 2010; 92: 83-92. [CrossRef]
50. Stovall DW, Bailey AP, Pastore LM. Assessment of insulin resistance and impaired glucose tolerance in lean women with polycystic ovary syndrome. J Womens Health (Larchmt) 2011; 20: 37-43. [CrossRef]
51. Dilbaz B, Çinar M, Özkaya E, Vanli Tonyali N, Dilbaz S. Health Related Quality of Life Among Different PCOS Phenotypes of Infertile Women. J Turk Ger Gynecol Assoc 2012; 13: 247-52. [CrossRef]
52. Özsoy S. Psychiatric status and approach in polycystic ovary syndrome and hirsutism. Turkiye Klinikleri J Endocrin-Special Topics 2009; 2: 126-30.
53. Tunç S, Tanrikulu L, Özcan L, Yenicesu O, Akin Su F, Subasi B. Psychopathological symptoms in adolescents with hirsutismus. The Journal of Gynecology - Obstetrics and Neonatology 2013; 10: 1518-21.
54. Vgontzas AN, Legro RS, Bixler EO, Grayev A, Kales A, Chrousos GP. Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: role of insulin resistance. J Clin Endocrinol Metab 2001; 86: 517-20. [CrossRef]
55. Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, et al. Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA 2004; 292: 1440-6. [CrossRef]
56. Zawadzki J, Dunaif A. Diagnostic Criteria for Polycystic Ovary Syndrome: towards a Rational Approach. In: Dunaif A, Givens J, Haseltine F, Merriam G, editors. Polycystic Ovary Syndrome. Blackwell Scientific Publications, Cambridge. 1992.p.377.
57. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81: 19-25. [CrossRef]