Haemophilus ducreyi as a cause of skin ulcers in children from a yaws-endemic area of Papua New Guinea: A prospective cohort study

The Lancet Global Health

Volumn 2, Issue 4, 2014, Pages

  Mitjà, Oriol ^a,b   Lukehart, Sheila A ^c   Pokowas, Gideon ^b   Moses, Penias ^b   Kapa, August ^b   Godornes, Charmie ^c   Robson, Jennifer ^d   Cherian, Sarah ^d   Houinei, Wendy ^e   Kazadi, Walter ^f   Siba, Peter ^g   De Lazzari, Elisa ^a   Bassat, Quique ^a  

^a CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^b Lihir Medical Centre International SOS   (Papua New Guinea)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Department of Global Health University of Washington ^*  (Australia)

^e National Department for Health   (Papua New Guinea)

^f WORLD HEALTH ORGANIZATION   (Switzerland)

^g PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BACTERIAL PROTEIN; HEMOGLOBIN BETA CHAIN;

ADOLESCENT; ARTICLE; CHILD; COHORT ANALYSIS; FEMALE; FLUORESCENT TREPONEMA ANTIBODY TEST; FUNDING; HAEMOPHILUS DUCREYI; HEMAGGLUTINATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PAPUA NEW GUINEA; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; PROSPECTIVE STUDY; SINGLE DRUG DOSE; SKIN ULCER; SYPHILIS SEROLOGY; TREPONEMA PALLIDUM; YAWS; CHANCROID; ENDEMIC DISEASE; HEMAGGLUTINATION TEST; MICROBIOLOGY; MIXED INFECTION; PATHOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PREVALENCE; SYPHILIS; ULCER;

ADOLESCENT; CHANCROID; CHILD; CHILD, PRESCHOOL; COINFECTION; ENDEMIC DISEASES; FEMALE; HAEMOPHILUS DUCREYI; HEMAGGLUTINATION TESTS; HUMANS; MALE; PAPUA NEW GUINEA; POLYMERASE CHAIN REACTION; PREVALENCE; PROSPECTIVE STUDIES; SKIN ULCER; SYPHILIS; SYPHILIS SERODIAGNOSIS; TREPONEMA PALLIDUM; ULCER; YAWS;

EID: 84896943505     PISSN: None     EISSN: 2214109X     Source Type: Journal    
DOI: 10.1016/S2214-109X(14)70019-1     Document Type: Article

References (29)

1. Mitjà O, Asiedu K, Mabey D Yaws. Lancet 2013, 381:763-773.
2. de Noray G, Capuano C, Abel M Campaign to eradicate yaws on Santo island, Vanuatu 2001. Med Trop 2003, 63:159-162.
3. Fegan D, Glennon MJ, Thami Y, Pakoa G Resurgence of yaws in Tanna, Vanuatu: time for a new approach?. Trop Doct 2010, 40:68-69.
4. Marckmann P, Højbjerg T, von Eyben FE, Christensen I Imported pedal chancroid: case report. Genitourin Med 1989, 65:126-127.
5. Ussher J, Wilson E, Campanella S, Taylor SL, Roberts SA Haemophilus ducreyi causing chronic skin ulceration in children visiting Samoa. Clin Infect Dis 2007, 44:85-87.
6. Peel TN, Bhatti D, De Boer JC, Stratov I, Spelman DW Chronic cutaneous ulcers secondary to Haemophilus ducreyi infection. Med J Aust 2010, 192:348-350.
7. McBride WJ, Hannah RC, Le Cornec GM, Bletchley C Cutaneous chancroid in a visitor from Vanuatu. Australas J Dermatol 2008, 49:98-99.
8. Eradication of yaws-the Morges Strategy. Wkly Epidemiol Rec 2012, 87:189-194. WHO.
9. Mitja O, Hays R, Ipai A, et al. Outcome predictors in treatment of yaws. Emerg Infect Dis 2011, 17:1083-1085.
10. Summary report of a consultation on the eradication of yaws. 5-7 March 2012 2012, WHO, World Health Organization, Geneva.
11. Mitjà O, Hays R, Ipai A, et al. Single-dose azithromycin versus benzathine benzylpenicillin for treatment of yaws in children in Papua New Guinea: an open-label, non-inferiority, randomised trial. Lancet 2012, 379:342-347.
12. Autier P, Delcambe JF, Sangare D, et al. Etudes sérologiques et cliniques sur la tréponématose endémique en République du Mali. Ann Soc Belge Méd Trop 1989, 69:319-329.
13. Lukehart SA, Godornes C, Molini B, et al. Macrolide resistance in Treponema pallidum in the United States and Ireland. N Engl J Med 2004, 351:154-158.
14. Centurion-Lara A, Castro C, Shaffer JM, et al. Detection of Treponema pallidum by a sensitive reverse transcriptase polymerase chain reaction. J Clin Microbiol 1997, 35:1348-1352.
15. Marra CM, Sahi SK, Tantalo LC, et al. Enhanced molecular typing of Treponema pallidum: geographical distribution of strain types and association with neurosyphilis. J Infect Dis 2010, 202:1380-1388.
16. Centurion-Lara A, Giacani L, Godornes C, et al. Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains. PLoS Negl Trop Dis 2013, 7:2222.
17. Orle KA, Gates CA, Martin DH, Body BA, Weiss JB Simultaneous PCR detection of Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus types 1 and 2 from genital ulcers. J Clin Microbiol 1996, 34:49-54.
18. Al-Tawfiq JA, Harezlak J, Katz BP, Spinola SM Cumulative experience with Haemophilus ducreyi 35000 in the human model of experimental infection. Sex Transm Dis 2000, 27:111-114.
19. Plummer FA, D'Costa LJ, Nsanze H, et al. Clinical and microbiologic studies of genital ulcers in Kenyan women. Sex Transm Dis 1985, 12:193-197.
20. Bogaerts J, Kestens L, van Dyck E, Tello WM, Akingeneye J, Mukantabana V Genital ulcers in a primary health clinic in Rwanda: impact of HIV infection on diagnosis and ulcer healing (1986-1992). Int J STD AIDS 1998, 9:706-710.
21. O'Farrell N, Hoosen AA, Coetzee KD, van den Ende J Genital ulcer disease in men in Durban, South Africa. Genitourin Med 1991, 67:327-330.
22. Chua SH, Cheong WK Genital ulcer disease in patients attending a public sexually transmitted disease clinic in Singapore: an epidemiologic study. Ann Acad Med Singapore 1995, 24:510-514.
23. Thirumoorthy T The epidemiology of sexually transmitted diseases in Southeast Asia and the western Pacific. Semin Dermatol 1990, 9:102-104.
24. Guidelines for the management of sexually transmitted infections in female sex workers 2002, WHO Regional Office for the Western Pacific, World Health Organization Regional Office for the Western Pacific STI, HIV and AIDS Focus, Manila, Philippines.
25. Trees DL, Morse SA Chancroid and Haemophilus ducreyi: an update. Clin Microbiol Rev 1995, 8:357-375.
26. Spinola SM, Wild LM, Apicella MA, et al. Experimental human infection with Haemophilus ducreyi. J Infect Dis 1994, 169:1146-1150.
27. Al-Tawfiq JA, Thornton AC, Katz BP, et al. Standardization of the experimental model of Haemophilus ducreyi infection in human subjects. J Infect Dis 1998, 178:1684-1687.
28. Pillay A, Chen CY, Reynolds MG, et al. Laboratory-confirmed case of yaws in a 10-year-old boy from the Republic of the Congo. J Clin Microbiol 2011, 49:4013-4015.
29. Workowski KA, Berman S Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep 2010, 59:1-110. Centers for Disease Control and Prevention (CDC).