Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination

The Scientific World Journal

Volumn 2014, Issue , 2014, Pages

  Lustosa, Suzana Angelica Silva ^a,b   De Souza Viana, Luciano ^a,c   Affonso Jr , Renato José ^a,c   Silva, Sandra Regina Morini ^a,c   Denadai, Marcos Vinicius Araujo ^a,c   De Toledo, Silvia Regina Caminada ^a   Oliveira, Indhira Dias ^a   Matos, Delcio ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b Hospital Municipal Dr Munir Rafful   (Brazil)

^c BARRETOS CANCER HOSPITAL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA3 INTEGRIN; ALPHA5 INTEGRIN; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRONECTIN; FIBRONECTIN 1; GELATINASE A; GELATINASE B; KI 67 ANTIGEN; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR; SCLEROPROTEIN; TUMOR PROTEIN;

ADULT; ADVANCED CANCER; AGED; ANTIGEN ANTIBODY REACTION; ARTICLE; CANCER GROWTH; CANCER STAGING; CANCER SURGERY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISTANT METASTASIS; DNA MICROARRAY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENE PRODUCT; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OVARY METASTASIS; PERITONEUM METASTASIS; PRIMARY TUMOR; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; TUMOR DIFFERENTIATION; VERY ELDERLY; YOUNG ADULT; COLORECTAL TUMOR; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; TUMOR INVASION;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; YOUNG ADULT;

EID: 84896932885     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2014/102541     Document Type: Article

References (46)

1. Rossi B. M., Nakagawa W. T., Ferreira F. O., Junior S. A., Lopes A., Colon, Rectal and Anal Cancer 2004 São Paulo, Brazil Lemar e Tecmedd
2. Chen Y.-X., Wang Y., Fu C.-C., Diao F., Song L.-N., Li Z.-B., Yang R., Lu J., Dexamethasone enhances cell resistance to chemotherapy by increasing adhesion to extracellular matrix in human ovarian cancer cells. Endocrine-Related Cancer 2010 17 1 39 50 2-s2.0-77449129300 10.1677/ERC-08-0296
3. Murphy G., Koklitis P., Carne A. F., Dissociation of tissue inhibitor of metalloproteinases (TIMP) from enzyme complexes yields fully active inhibitor. Biochemical Journal 1989 261 3 1031 1034 2-s2.0-0024402822 (Pubitemid 19209546)
4. Ghilardi G., Biondi M. L., Mangoni J., Leviti S., DeMonti M., Guagnellini E., Scorza R., Matrix metalloproteinase-1 promoter polymorphism 1 g/2 g is correlated with colorectal cancer invasiveness. Clinical Cancer Research 2001 7 8 2344 2346 2-s2.0-0034886304 (Pubitemid 32751634)
5. von Lampe B., Stallmach A., Riecken E. O., Altered glycosylation of integrin adhesion molecules in colorectal cancer cells and decreased adhesion to the extracellular matrix. Gut 1993 34 6 829 836 2-s2.0-0027252857 (Pubitemid 23185113)
6. Streit M., Schmidt R., Hilgenfeld R. U., Thiel E., Kreuser E.-D., Adhesion receptors in malignant transformation and dissemination of gastrointestinal tumors. Journal of Molecular Medicine 1996 74 5 253 268 2-s2.0-0029997916 10.1007/s001090050027 (Pubitemid 26176682)
7. Jinka R., Kapoor R., Sistla P. G., Raj T. A., Pande G., Alterations in cell-extracellular matrix interactions during progression of cancers. International Journal of Cell Biology 2012 2012 8 2-s2.0-84856437751 10.1155/2012/219196 219196
8. van der Jagt M. F. P., Wobbes T., Strobbe L. J. A., Sweep F. C. G. J., Span P. N., Metalloproteinases and their regulators in colorectal cancer. Journal of Surgical Oncology 2010 101 3 259 269 2-s2.0-77249158924 10.1002/jso.21462
9. Surlin V., Ioana M., Pleşea I. E., Genetic patterns of metalloproteinases and their tissue inhibitors-clinicopathologic and prognostic significance in colorectal cancer. Romanian Journal of Morphology and Embryology 2011 52 1, supplement 231 236
10. Navarro V. P., Nelson-Filho P., Silva L. A. B., Freitas A. C., Matrix metalloproteinases participation in physiological and pathologic oral processes. Revista de Odontologia da UNESP 2006 35 4 233 238
11. Jucá M., Nunes B. L. B. B. P., Menezes H. L., Gomes E. G. A., Matos D., Metalloproteinases 1 and 7 and colorectal cancer. Revista Brasileira de Coloproctologia 2008 28 3 353 362 10.1590/S0101-98802008000300016
12. Viana L. S., Afonso R. J. Jr., Morini S. R., Denadai M. V., Souza C. S., Waisberg J., Matos D., Relationship between the expression of the extracellular matrix genes sparc, sppp1, fn1, itga5 and itgav and clinicopathological parameters of tumor progression and colorectal cancer dissemination. Oncology 2013 84 81 91
13. Denadai M. V. A., Viana L. S., Afonso R. J. Jr., Silva S. R., Oliveira I. D., Toledo S. R., Matos D., Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma. BMC Clinical Pathology 2013 13 article 16 10.1186/1472-6890-13-16
14. Nowell P. C., Tumor progression: a brief historical perspective. Seminars in Cancer Biology 2002 12 4 261 266 2-s2.0-0036376720 10.1016/S1044-579X(02) 00012-3 (Pubitemid 35034570)
15. Arnaout M. A., Goodman S. L., Xiong J.-P., Structure and mechanics of integrin-based cell adhesion. Current Opinion in Cell Biology 2007 19 5 495 507 2-s2.0-35648978998 10.1016/j.ceb.2007.08.002 (Pubitemid 350019555)
16. Avraamides C. J., Garmy-Susini B., Varner J. A., Integrins in angiogenesis and lymphangiogenesis. Nature Reviews Cancer 2008 8 8 604 617 2-s2.0-47949114114 10.1038/nrc2353
17. Pinon P., Wehrle-Haller B., Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation. Pigment Cell and Melanoma Research 2011 24 2 282 294 2-s2.0-79952613582 10.1111/j.1755-148X.2010.00806.x
18. Nicoloso M. S., Spizzo R., Shimizu M., Rossi S., Calin G. A., MicroRNAs-the micro steering wheel of tumour metastases. Nature Reviews Cancer 2009 9 4 293 302 2-s2.0-63049085576 10.1038/nrc2619
19. McElroy M. K., Kaushal S., Cao H. S. T., Moossa A. R., Talamini M. A., Hoffman R. M., Bouvet M., Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis. Molecular Cancer Therapeutics 2009 8 7 1779 1786 2-s2.0-67651146532 10.1158/1535-7163.MCT-09-0122
20. Raeder S., Utheim T. P., Utheim Ø. A., Nicolaissen B., Roald B., Cai Y., Haug K., Kvalheim A., Messelt E. B., Drolsum L., Reed J. C., Lyberg T., Effects of organ culture and optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium. Investigative Ophthalmology and Visual Science 2007 48 12 5484 5493 2-s2.0-38549097663 10.1167/iovs.07-0494 (Pubitemid 351260848)
21. Bertucci F., Salas S., Eysteries S., Nasser V., Finetti P., Ginestier C., Charafe-Jauffret E., Loriod B., Bachelart L., Montfort J., Victorero G., Viret F., Ollendorff V., Fert V., Giovaninni M., Delpero J.-R., Nguyen C., Viens P., Monges G., Birnbaum D., Houlgatte R., Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene 2004 23 7 1377 1391 2-s2.0-1442308342 10.1038/sj.onc.1207262 (Pubitemid 38406833)
22. Hoos A., Cordon-Cardo C., Tissue microarray profiling of cancer specimens and cell lines: opportunities and limitations. Laboratory Investigation 2001 81 10 1331 1338 2-s2.0-0034769529 (Pubitemid 32980155)
23. Spearman C., The proof and measurement of association between two things. International Journal of Epidemiology 2010 39 5 1137 1150 10.1093/ije/dyq191
24. Stallmach A., von Lampe B., Matthes H., Bornhoft G., Riecken E. O., Diminished expression of integrin adhesion molecules on human colonic epithelial cells during the benign to malign tumour transformation. Gut 1992 33 3 342 346 2-s2.0-0026537524
25. Pupa S. M., Ménard S., Forti S., Tagliabue E., New insights into the role of extracellular matrix during tumor onset and progression. Journal of Cellular Physiology 2002 192 3 259 267 2-s2.0-0036329807 10.1002/jcp.10142 (Pubitemid 34827603)
26. Borg T. K., It's the matrix! ECM, proteases, and cancer. The American Journal of Pathology 2004 164 4 1141 1142 2-s2.0-1642321893 (Pubitemid 38387780)
27. Ueda T., Volinia S., Okumura H., Shimizu M., Taccioli C., Rossi S., Alder H., Liu C.-G., Oue N., Yasui W., Yoshida K., Sasaki H., Nomura S., Seto Y., Kaminishi M., Calin G. A., Croce C. M., Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. The Lancet Oncology 2010 11 2 136 146 2-s2.0-75249107416 10.1016/S1470-2045(09) 70343-2
28. Chen N., Ye X.-C., Chu K., Navone N. M., Sage E. H., Yu-Lee L.-Y., Logothetis C. J., Lin S.-H., A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells. Cancer Research 2007 67 14 6544 6548 2-s2.0-34547122493 10.1158/0008-5472.CAN- 07-1330 (Pubitemid 47105497)
29. Kononen J., Bubendorf L., Kallioniemi A., Bärlund M., Schraml P., Leighton S., Torhorst J., Mihatsch M. J., Sauter G., Kallioniemi O.-P., Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nature Medicine 1998 4 7 844 847 2-s2.0-0031822837 10.1038/nm0798-844 (Pubitemid 28331029)
30. Andrade V. P., Cunha I. W., Silva E. M., Ayala F., Sato Y., Ferrreira S. S., Nascimento C. F., Soares F. A., Tissue microarrays: high throughput and low cost avaiable for pathologists. Jornal Brasileiro de Patologia e Medicina Laboratorial 2007 43 1 55 60 10.1590/S1676-24442007000100011
31. Haler J., Nasralla M., Nicolson G. L., Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components. British Journal of Cancer 1999 80 12 1867 1874 2-s2.0-0032779782 10.1038/sj.bjc.6690614 (Pubitemid 29391268)
32. Bianchi A., Gervasi M. E., Bakin A. V., Role of β 5-integrin in epithelial-mesenchymal transition in response to TGF β Cell Cycle 2010 9 8 1647 1659 2-s2.0-77953550880
33. 1-integrin function. The EMBO Journal 2007 26 12 2832 2842 2-s2.0-34250859492 10.1038/sj.emboj.7601738 (Pubitemid 46975787)
34. Desgrosellier J. S., Cheresh D. A., Integrins in cancer: biological implications and therapeutic opportunities. Nature Reviews Cancer 2010 10 1 9 22 2-s2.0-72949119124 10.1038/nrc2748
35. Pesta M., Topolcan O., Holubec L. Jr., Rupert K., Cerna M., Holubec L., Treska V., Finek J., Cerny R., Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples. Anticancer Research 2007 27 4 1863 1867 2-s2.0-34250775911 (Pubitemid 46954688)
36. Oshima T., Kunisaki C., Yoshihara K., Yamada R., Yamamoto N., Sato T., Makino H., Yamagishi S., Nagano Y., Fujii S., Shiozawa M., Akaike M., Wada N., Rino Y., Masuda M., Tanaka K., Imada T., Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer. Oncology Reports 2008 19 5 1285 1291 2-s2.0-47549116029
37. Cavdar Z., Canda A. E., Terzi C., Sarioglu S., Fuzun M., Oktay G., Role of gelatinases (matrix metalloproteinases 2 and 9), vascular endothelial growth factor and endostatin on clinicopathological behaviour of rectal cancer. Colorectal Disease 2011 13 2 154 160 2-s2.0-78751690198 10.1111/j.1463-1318. 2009.02105.x
38. Delektorskaya V. V., Kushlinskii N. E., Clinical significance of the content of biomolecular markers in invasive front of colon carcinomas. Bulletin of Experimental Biology and Medicine 2011 150 3 368 371 2-s2.0-79951724870 10.1007/s10517-011-1144-z
39. Murnane M. J., Cai J., Shuja S., McAneny D., Klepeis V., Willett J. B., Active MMP-2 effectively identifies the presence of colorectal cancer. International Journal of Cancer 2009 125 12 2893 2902 2-s2.0-72449145498 10.1002/ijc.24682
40. Bendardaf R., Buhmeida A., Hilska M., Laato M., Syräjnen S., Syrjänen K., Collan Y., Pyrhönen S., MMP-9 (gelatinase B) expression is associated with disease-free survival and disease-specific survival in colorectal cancer patients. Cancer Investigation 2010 28 1 38 43 2-s2.0-72449139066 10.3109/07357900802672761
41. Unsal D., Akyurek N., Uner A., Erpolat O. P., Han U., Akmansu M., Mentes B. B., Dursun A., Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy. American Journal of Clinical Oncology 2008 31 1 55 63 2-s2.0-42449163469 10.1097/COC.0b013e318068b4e2
42. Zucker S., Vacirca J., Role of matrix metalloproteinases (MMPs) in colorectal cancer. Cancer and Metastasis Reviews 2004 23 1-2 101 117 2-s2.0-1242292412 10.1023/A:1025867130437 (Pubitemid 38221598)
43. Chu D., Zhao Z., Zhou Y., Li Y., Li J., Zheng J., Zhao Q., Wang W., Matrix metalloproteinase-9 is associated with relapse and prognosis of patients with colorectal cancer. Annals of Surgical Oncology 2012 19 1 318 325 2-s2.0-84856658392 10.1245/s10434-011-1686-3
44. Herszényi L., Sipos F., Galamb O., Solymosi N., Hritz I., Miheller P., Berczi L., Molnár B., Tulassay Z., Matrix metalloproteinase-9 expression in the normal mucosa-adenoma-dysplasia-adenocarcinoma sequence of the colon. Pathology and Oncology Research 2008 14 1 31 37 2-s2.0-49349085163 10.1007/s12253-008-9004-5
45. Buhmeida A., Bendardaf R., Hilska M., Collan Y., Laato M., Syrjänen S., Syrjänen K., Pyrhönen S., Prognostic significance of matrix metalloproteinase-9 (MMP-9) in stage II colorectal carcinoma. Journal of Gastrointestinal Cancer 2009 40 3-4 91 97 2-s2.0-73549118990 10.1007/s12029-009-9091-x
46. Loy T. S., Kaplan P. A., Villous adenocarcinoma of the colon and rectum: a clinicopothologic study of 36 cases. The American Journal of Surgical Pathology 2004 28 11 1460 1465 2-s2.0-7044233683 10.1097/01.pas.0000141394. 64707.02 (Pubitemid 39425512)