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Volumn 9, Issue 3, 2014, Pages 785-795

Identification of a new class of small molecules that efficiently reactivate latent Epstein-Barr virus

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT; GANCICLOVIR; HISTONE DEACETYLASE INHIBITOR; PHORBOL ESTER; TETRAHYDROCARBOLINE DERIVATIVE; UNCLASSIFIED DRUG; BZLF1 PROTEIN, HERPESVIRUS 4, HUMAN; IMMEDIATE EARLY PROTEIN; MOLECULAR LIBRARY; TRANSACTIVATOR PROTEIN;

EID: 84896929392     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb4006326     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 0003401079 scopus 로고    scopus 로고
    • 5 th ed. Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia
    • Rickinson, A. B. and Kieff, E. (2007) Epstein-Barr Virus, 5 th ed., Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia.
    • (2007) Epstein-Barr Virus
    • Rickinson, A.B.1    Kieff, E.2
  • 2
    • 0003401086 scopus 로고    scopus 로고
    • 5 th ed. Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia
    • Kieff, E. (2007) Epstein-Barr Virus and Its Replication, 5 th ed., Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia.
    • (2007) Epstein-Barr Virus and Its Replication
    • Kieff, E.1
  • 3
    • 23244448471 scopus 로고    scopus 로고
    • EBV the prototypical human tumor virus - Just how bad is it'
    • quiz 262
    • Thorley-Lawson, D. A. (2005) EBV the prototypical human tumor virus - just how bad is it' J. Allergy Clin. Immunol. 116, 251-261 quiz 262
    • (2005) J. Allergy Clin. Immunol. , vol.116 , pp. 251-261
    • Thorley-Lawson, D.A.1
  • 4
    • 33847276039 scopus 로고    scopus 로고
    • Epstein-Barr virus infection in humans: From harmless to life endangering virus-lymphocyte interactions
    • Klein, E., Kis, L. L., and Klein, G. (2007) Epstein-Barr virus infection in humans: from harmless to life endangering virus-lymphocyte interactions Oncogene 26, 1297-1305
    • (2007) Oncogene , vol.26 , pp. 1297-1305
    • Klein, E.1    Kis, L.L.2    Klein, G.3
  • 5
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • Raab-Traub, N. (2002) Epstein-Barr virus in the pathogenesis of NPC Sem. Cancer Biol. 12, 431-441
    • (2002) Sem. Cancer Biol. , vol.12 , pp. 431-441
    • Raab-Traub, N.1
  • 6
    • 80054003491 scopus 로고    scopus 로고
    • Epstein-Barr virus-associated gastric carcinoma
    • Fukayama, M. and Ushiku, T. (2011) Epstein-Barr virus-associated gastric carcinoma Pathol., Res. Pract. 207, 529-537
    • (2011) Pathol., Res. Pract. , vol.207 , pp. 529-537
    • Fukayama, M.1    Ushiku, T.2
  • 8
    • 14544302778 scopus 로고    scopus 로고
    • Post-transplant lymphoproliferative Disorders
    • Gottschalk, S., Rooney, C. M., and Heslop, H. E. (2004) Post-transplant lymphoproliferative Disorders Annu. Rev. Med. 56, 29-44
    • (2004) Annu. Rev. Med. , vol.56 , pp. 29-44
    • Gottschalk, S.1    Rooney, C.M.2    Heslop, H.E.3
  • 9
    • 0027848541 scopus 로고
    • Epstein-Barr virus-latent gene expression and tumor cell phenotype in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. Correlation of lymphoma phenotype with three distinct patterns of viral latency
    • Hamilton-Dutoit, S. J., Rea, D., Raphael, M., Sandvej, K., Delecluse, H. J., Gisselbrecht, C., Marelle, L., van Krieken, H. J., and Pallesen, G. (1993) Epstein-Barr virus-latent gene expression and tumor cell phenotype in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. Correlation of lymphoma phenotype with three distinct patterns of viral latency Am. J. Pathol. 143, 1072-1085
    • (1993) Am. J. Pathol. , vol.143 , pp. 1072-1085
    • Hamilton-Dutoit, S.J.1    Rea, D.2    Raphael, M.3    Sandvej, K.4    Delecluse, H.J.5    Gisselbrecht, C.6    Marelle, L.7    Van Krieken, H.J.8    Pallesen, G.9
  • 11
    • 4944266319 scopus 로고    scopus 로고
    • Epstein-Barr virus: 40 years on
    • Young, L. S. and Rickinson, A. B. (2004) Epstein-Barr virus: 40 years on Nat. Rev. Cancer 4, 757-768
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 757-768
    • Young, L.S.1    Rickinson, A.B.2
  • 12
    • 0030067422 scopus 로고    scopus 로고
    • Switching viral latency to viral lysis: A novel therapeutic approach for Epstein-Barr virus-associated neoplasia
    • Gutierrez, M. I., Judde, J. G., Magrath, I. T., and Bhatia, K. G. (1996) Switching viral latency to viral lysis: a novel therapeutic approach for Epstein-Barr virus-associated neoplasia Cancer Res. 56, 969-972
    • (1996) Cancer Res. , vol.56 , pp. 969-972
    • Gutierrez, M.I.1    Judde, J.G.2    Magrath, I.T.3    Bhatia, K.G.4
  • 13
    • 0032550754 scopus 로고    scopus 로고
    • Gene therapy strategies for treating Epstein-Barr virus-associated lymphomas: Comparison of two different Epstein-Barr virus-based vectors
    • Kenney, S., Ge, J. Q., Westphal, E. M., and Olsen, J. (1998) Gene therapy strategies for treating Epstein-Barr virus-associated lymphomas: comparison of two different Epstein-Barr virus-based vectors Human Gene Therapy 9, 1131-1141
    • (1998) Human Gene Therapy , vol.9 , pp. 1131-1141
    • Kenney, S.1    Ge, J.Q.2    Westphal, E.M.3    Olsen, J.4
  • 16
    • 84863039812 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents
    • Ghosh, S. K., Perrine, S. P., Williams, R. M., and Faller, D. V. (2012) Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents Blood 119, 1008-1017
    • (2012) Blood , vol.119 , pp. 1008-1017
    • Ghosh, S.K.1    Perrine, S.P.2    Williams, R.M.3    Faller, D.V.4
  • 17
    • 79959405603 scopus 로고    scopus 로고
    • Bortezomib induction of C/EBPbeta mediates Epstein-Barr virus lytic activation in Burkitt lymphoma
    • Shirley, C. M., Chen, J., Shamay, M., Li, H., Zahnow, C. A., Hayward, S. D., and Ambinder, R. F. (2011) Bortezomib induction of C/EBPbeta mediates Epstein-Barr virus lytic activation in Burkitt lymphoma Blood 117, 6297-6303
    • (2011) Blood , vol.117 , pp. 6297-6303
    • Shirley, C.M.1    Chen, J.2    Shamay, M.3    Li, H.4    Zahnow, C.A.5    Hayward, S.D.6    Ambinder, R.F.7
  • 18
    • 0021988550 scopus 로고
    • Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells
    • Yates, J. L., Warren, N., and Sugden, B. (1985) Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells Nature 313, 812-815
    • (1985) Nature , vol.313 , pp. 812-815
    • Yates, J.L.1    Warren, N.2    Sugden, B.3
  • 19
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang, J. H., Chung, T. D., and Oldenburg, K. R. (1999) A simple statistical parameter for use in evaluation and validation of high throughput screening assays J. Biomol. Screening 4, 67-73
    • (1999) J. Biomol. Screening , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 20
    • 84865455985 scopus 로고    scopus 로고
    • Firefly luciferase in chemical biology: A compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter
    • Thorne, N., Shen, M., Lea, W. A., Simeonov, A., Lovell, S., Auld, D. S., and Inglese, J. (2012) Firefly luciferase in chemical biology: a compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter Chem. Biol. 19, 1060-1072
    • (2012) Chem. Biol. , vol.19 , pp. 1060-1072
    • Thorne, N.1    Shen, M.2    Lea, W.A.3    Simeonov, A.4    Lovell, S.5    Auld, D.S.6    Inglese, J.7
  • 21
    • 70349748580 scopus 로고    scopus 로고
    • Stimulus duration and response time independently influence the kinetics of lytic cycle reactivation of Epstein-Barr virus
    • Countryman, J., Gradoville, L., Bhaduri-McIntosh, S., Ye, J., Heston, L., Himmelfarb, S., Shedd, D., and Miller, G. (2009) Stimulus duration and response time independently influence the kinetics of lytic cycle reactivation of Epstein-Barr virus J. Virol. 83, 10694-10709
    • (2009) J. Virol. , vol.83 , pp. 10694-10709
    • Countryman, J.1    Gradoville, L.2    Bhaduri-Mcintosh, S.3    Ye, J.4    Heston, L.5    Himmelfarb, S.6    Shedd, D.7    Miller, G.8
  • 24
    • 79956067296 scopus 로고    scopus 로고
    • Valproic acid antagonizes the capacity of other histone deacetylase inhibitors to activate the Epstein-barr virus lytic cycle
    • Daigle, D., Gradoville, L., Tuck, D., Schulz, V., Wang'ondu, R., Ye, J., Gorres, K., and Miller, G. (2011) Valproic acid antagonizes the capacity of other histone deacetylase inhibitors to activate the Epstein-barr virus lytic cycle J. Virol. 85, 5628-5643
    • (2011) J. Virol. , vol.85 , pp. 5628-5643
    • Daigle, D.1    Gradoville, L.2    Tuck, D.3    Schulz, V.4    Wangondu, R.5    Ye, J.6    Gorres, K.7    Miller, G.8
  • 25
    • 73849116103 scopus 로고    scopus 로고
    • Upregulation of STAT3 marks Burkitt lymphoma cells refractory to Epstein-Barr virus lytic cycle induction by HDAC inhibitors
    • Daigle, D., Megyola, C., El-Guindy, A., Gradoville, L., Tuck, D., Miller, G., and Bhaduri-McIntosh, S. (2010) Upregulation of STAT3 marks Burkitt lymphoma cells refractory to Epstein-Barr virus lytic cycle induction by HDAC inhibitors J. Virol. 84, 993-1004
    • (2010) J. Virol. , vol.84 , pp. 993-1004
    • Daigle, D.1    Megyola, C.2    El-Guindy, A.3    Gradoville, L.4    Tuck, D.5    Miller, G.6    Bhaduri-Mcintosh, S.7
  • 27
    • 84864182351 scopus 로고    scopus 로고
    • Artificial analogs of naturally occurring tumor promoters as biochemical tools and therapeutic leads
    • Nakagawa, Y. (2012) Artificial analogs of naturally occurring tumor promoters as biochemical tools and therapeutic leads Biosci. Biotechnol. Biochem. 76, 1262-1274
    • (2012) Biosci. Biotechnol. Biochem. , vol.76 , pp. 1262-1274
    • Nakagawa, Y.1
  • 28
    • 0035919638 scopus 로고    scopus 로고
    • 12-O-tetradecanoylphorbol-13-acetate induces Epstein-Barr virus reactivation via NF-kappaB and AP-1 as regulated by protein kinase C and mitogen-activated protein kinase
    • Gao, X., Ikuta, K., Tajima, M., and Sairenji, T. (2001) 12-O-tetradecanoylphorbol-13-acetate induces Epstein-Barr virus reactivation via NF-kappaB and AP-1 as regulated by protein kinase C and mitogen-activated protein kinase Virology 286, 91-99
    • (2001) Virology , vol.286 , pp. 91-99
    • Gao, X.1    Ikuta, K.2    Tajima, M.3    Sairenji, T.4
  • 29
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacylglycerol effectors in cancer
    • Griner, E. M. and Kazanietz, M. G. (2007) Protein kinase C and other diacylglycerol effectors in cancer Nat. Rev. Cancer 7, 281-294
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1    Kazanietz, M.G.2
  • 30
    • 18744390485 scopus 로고    scopus 로고
    • Reactivation of Epstein-Barr virus from latency
    • Amon, W. and Farrell, P. J. (2005) Reactivation of Epstein-Barr virus from latency Rev. Med. Virol. 15, 149-156
    • (2005) Rev. Med. Virol. , vol.15 , pp. 149-156
    • Amon, W.1    Farrell, P.J.2
  • 31
    • 79251485979 scopus 로고    scopus 로고
    • X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein-Barr virus in co-infected primary effusion lymphoma
    • Lai, I. Y., Farrell, P. J., and Kellam, P. (2011) X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein-Barr virus in co-infected primary effusion lymphoma J. Gen. Virol. 92, 421-431
    • (2011) J. Gen. Virol. , vol.92 , pp. 421-431
    • Lai, I.Y.1    Farrell, P.J.2    Kellam, P.3
  • 32
    • 77649188072 scopus 로고    scopus 로고
    • Cellular factors associated with latency and spontaneous Epstein-Barr virus reactivation in B-lymphoblastoid cell lines
    • Davies, M. L., Xu, S., Lyons-Weiler, J., Rosendorff, A., Webber, S. A., Wasil, L. R., Metes, D., and Rowe, D. T. (2010) Cellular factors associated with latency and spontaneous Epstein-Barr virus reactivation in B-lymphoblastoid cell lines Virology 400, 53-67
    • (2010) Virology , vol.400 , pp. 53-67
    • Davies, M.L.1    Xu, S.2    Lyons-Weiler, J.3    Rosendorff, A.4    Webber, S.A.5    Wasil, L.R.6    Metes, D.7    Rowe, D.T.8
  • 34
    • 0141992797 scopus 로고    scopus 로고
    • The discovery of tadalafil: A novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1 H -imidazo[1',5':1,6]pyrido[3,4- b ]indole-1,3(2 H)-dione analogues
    • Daugan, A., Grondin, P., Ruault, C., Le Monnier de Gouville, A. C., Coste, H., Kirilovsky, J., Hyafil, F., and Labaudiniere, R. (2003) The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1 H -imidazo[1',5':1,6]pyrido[3,4- b ]indole-1,3(2 H)-dione analogues J. Med. Chem. 46, 4525-4532
    • (2003) J. Med. Chem. , vol.46 , pp. 4525-4532
    • Daugan, A.1    Grondin, P.2    Ruault, C.3    Le Monnier De Gouville, A.C.4    Coste, H.5    Kirilovsky, J.6    Hyafil, F.7    Labaudiniere, R.8
  • 35
    • 77958134523 scopus 로고    scopus 로고
    • CTCF prevents the epigenetic drift of EBV latency promoter Qp
    • e1001048
    • Tempera, I., Wiedmer, A., Dheekollu, J., and Lieberman, P. M. (2010) CTCF prevents the epigenetic drift of EBV latency promoter Qp PLoS Pathog. 6 e1001048
    • (2010) PLoS Pathog. , vol.6
    • Tempera, I.1    Wiedmer, A.2    Dheekollu, J.3    Lieberman, P.M.4
  • 36
    • 0034790899 scopus 로고    scopus 로고
    • Identification of acidic and aromatic residues in the Zta activation omain essential for Epstein-Barr virus reactivation
    • Deng, Z., Chen, C.-J., Zerby, D., Delecluse, H.-J., and Lieberman, P. M. (2001) Identification of acidic and aromatic residues in the Zta activation omain essential for Epstein-Barr virus reactivation J. Virol. 75, 10334-10347
    • (2001) J. Virol. , vol.75 , pp. 10334-10347
    • Deng, Z.1    Chen, C.-J.2    Zerby, D.3    Delecluse, H.-J.4    Lieberman, P.M.5
  • 37
    • 0035026624 scopus 로고    scopus 로고
    • Autostimulation of the Epstein-Barr virus BRLF1 promoter is mediated through consensus Sp1 and Sp3 binding sites
    • Ragoczy, T. and Miller, G. (2001) Autostimulation of the Epstein-Barr virus BRLF1 promoter is mediated through consensus Sp1 and Sp3 binding sites J. Virol. 75, 5240-5251
    • (2001) J. Virol. , vol.75 , pp. 5240-5251
    • Ragoczy, T.1    Miller, G.2
  • 38
    • 78650113600 scopus 로고    scopus 로고
    • Development of a high-throughput screen for inhibitors of Epstein-Barr virus EBNA1
    • Thompson, S., Messick, T., Schultz, D. C., Reichman, M., and Lieberman, P. M. (2010) Development of a high-throughput screen for inhibitors of Epstein-Barr virus EBNA1 J. Biomol. Screening 15, 1107-1115
    • (2010) J. Biomol. Screening , vol.15 , pp. 1107-1115
    • Thompson, S.1    Messick, T.2    Schultz, D.C.3    Reichman, M.4    Lieberman, P.M.5


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