-
1
-
-
80655127884
-
Treatment of metastatic breast cancer: state-of-the-art, subtypes and perspectives
-
El Saghir NS, Tfayli A, Hatoum HA, Nachef Z, Dinh P, Awada A. Treatment of metastatic breast cancer: state-of-the-art, subtypes and perspectives. Crit Rev Oncol Hematol. 2011; 80: 433-49
-
(2011)
Crit Rev Oncol Hematol.
, vol.80
, pp. 433-449
-
-
El Saghir, N.S.1
Tfayli, A.2
Hatoum, H.A.3
Nachef, Z.4
Dinh, P.5
Awada, A.6
-
2
-
-
67049133438
-
Treatment options for breast cancer resistant to anthracycline and taxane
-
Moreno-Aspitia A, Perez EA. Treatment options for breast cancer resistant to anthracycline and taxane. Mayo Clin Proc. 2009; 84: 533-45
-
(2009)
Mayo Clin Proc.
, vol.84
, pp. 533-545
-
-
Moreno-Aspitia, A.1
Perez, E.A.2
-
3
-
-
23144433687
-
The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth
-
Jordan MA, Kamath K, Manna T, et al. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth. Mol Cancer Ther. 2005; 4: 1086-95
-
(2005)
Mol Cancer Ther.
, vol.4
, pp. 1086-1095
-
-
Jordan, M.A.1
Kamath, K.2
Manna, T.3
-
4
-
-
76749127634
-
Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability
-
Smith JA, Wilson L, Azarenko O, et al. Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability. Biochemistry. 2010; 49: 1331-7
-
(2010)
Biochemistry.
, vol.49
, pp. 1331-1337
-
-
Smith, J.A.1
Wilson, L.2
Azarenko, O.3
-
5
-
-
78751525051
-
Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions
-
Towle MJ, Salvato KA, Wels BF, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011; 71: 496-505
-
(2011)
Cancer Res.
, vol.71
, pp. 496-505
-
-
Towle, M.J.1
Salvato, K.A.2
Wels, B.F.3
-
6
-
-
77957594393
-
Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine
-
Cortes J, Vahdat L, Blum JL, et al. Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabine. J Clin Oncol. 2010; 28: 3922-8.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 3922-3928
-
-
Cortes, J.1
Vahdat, L.2
Blum, J.L.3
-
7
-
-
67649908927
-
Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
Vahdat LT, Pruitt B, Fabian CJ, et al. Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol. 2009; 27: 2954-61.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 2954-2961
-
-
Vahdat, L.T.1
Pruitt, B.2
Fabian, C.J.3
-
8
-
-
84861733607
-
A phase II study of eribulin in Japanese patients with heavily pretreated metastatic breast cancer
-
Aogi K, Iwata H, Masuda N, et al. A phase II study of eribulin in Japanese patients with heavily pretreated metastatic breast cancer. Ann Oncol. 2012; 23: 1441-8.
-
(2012)
Ann Oncol.
, vol.23
, pp. 1441-1448
-
-
Aogi, K.1
Iwata, H.2
Masuda, N.3
-
9
-
-
79952487463
-
Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study
-
Cortes J, O'Shaughnessy J, Loesch D, et al. Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study. Lancet. 2011; 377: 914-23.
-
(2011)
Lancet.
, vol.377
, pp. 914-923
-
-
Cortes, J.1
O'Shaughnessy, J.2
Loesch, D.3
-
10
-
-
84859463274
-
Advances in the management of metastatic breast cancer: options beyond first-line chemotherapy
-
Ayoub JP, Verma Sh, Verma S. Advances in the management of metastatic breast cancer: options beyond first-line chemotherapy. Curr Oncol. 2012; 19: 91-105.
-
(2012)
Curr Oncol.
, vol.19
, pp. 91-105
-
-
Ayoub, J.P.1
Verma, S.2
Verma, S.3
-
11
-
-
54449095991
-
Trends in survival over the past two decades among white and black patients with newly diagnosed stage IV breast cancer
-
Dawood S, Broglio K, Gonzalez-Angulo AM, Buzdar AU, Hortobagyi GN, Giordano SH. Trends in survival over the past two decades among white and black patients with newly diagnosed stage IV breast cancer. J Clin Oncol. 2008; 26: 4891-8.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 4891-4898
-
-
Dawood, S.1
Broglio, K.2
Gonzalez-Angulo, A.M.3
Buzdar, A.U.4
Hortobagyi, G.N.5
Giordano, S.H.6
-
12
-
-
58049217470
-
Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer
-
Mauri D, Polyzos NP, Salanti G, Pavlidis N, Ioannidis JP. Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer. J Natl Cancer Inst. 2008; 100: 1780-91.
-
(2008)
J Natl Cancer Inst.
, vol.100
, pp. 1780-1791
-
-
Mauri, D.1
Polyzos, N.P.2
Salanti, G.3
Pavlidis, N.4
Ioannidis, J.P.5
-
13
-
-
80054850335
-
Extending the duration of first-line chemotherapy in metastatic breast cancer: a perspective review
-
Gennari A, D'amico M, Corradengo D. Extending the duration of first-line chemotherapy in metastatic breast cancer: a perspective review. Ther Adv Med Oncol. 2011; 3: 229-32.
-
(2011)
Ther Adv Med Oncol.
, vol.3
, pp. 229-232
-
-
Gennari, A.1
D'amico, M.2
Corradengo, D.3
-
15
-
-
84896909389
-
Beyond the second line chemotherapy in metastatic breast cancer: when stop the treatment between science and conscience.
-
Bernardo G, Palumbo R, Poggi G, et al. Beyond the second line chemotherapy in metastatic breast cancer: when stop the treatment between science and conscience. Cancer Res. 2010; 70 (Suppl 24): 446s.
-
(2010)
Cancer Res.
, vol.70
, Issue.SUPPL. 24
, pp. 446
-
-
Bernardo, G.1
Palumbo, R.2
Poggi, G.3
-
16
-
-
82955248028
-
Late lines of treatment benefit survival in metastatic breast cancer in current practice
-
Planchat E, Abrial C, Thivat E, et al. Late lines of treatment benefit survival in metastatic breast cancer in current practice? Breast. 2011; 20: 574-8.
-
(2011)
Breast.
, vol.20
, pp. 574-578
-
-
Planchat, E.1
Abrial, C.2
Thivat, E.3
-
17
-
-
37249038557
-
Impact of chemotherapy beyond the first line in patients with metastatic breast cancer
-
Dufresne A, Pivot X, Tournigand C, et al. Impact of chemotherapy beyond the first line in patients with metastatic breast cancer. Breast Cancer Res Treat. 2008; 107: 275-9.
-
(2008)
Breast Cancer Res Treat.
, vol.107
, pp. 275-279
-
-
Dufresne, A.1
Pivot, X.2
Tournigand, C.3
-
18
-
-
84896923380
-
Which patients with metastatic breast cancer benefit from subsequent lines of treatment? An update for clinicians
-
Palumbo R, Sottotetti F, Riccardi A, et al. Which patients with metastatic breast cancer benefit from subsequent lines of treatment? An update for clinicians. Ther Adv Med Oncol. 2013; 5: 334-50.
-
(2013)
Ther Adv Med Oncol.
, vol.5
, pp. 334-350
-
-
Palumbo, R.1
Sottotetti, F.2
Riccardi, A.3
-
19
-
-
79551519944
-
The place for eribulin in the treatment of metastatic breast cancer
-
Gradishar WJ. The place for eribulin in the treatment of metastatic breast cancer. Curr Oncol Rep. 2011; 13: 11-6.
-
(2011)
Curr Oncol Rep.
, vol.13
, pp. 11-16
-
-
Gradishar, W.J.1
-
20
-
-
84889576309
-
Reproducibility of research and preclinical validation: problems and solutions
-
Pusztai L, Hatzis C, Andre F. Reproducibility of research and preclinical validation: problems and solutions. Nat Rev Clin Oncol. 2013 Dec;10(12):720-4.
-
(2013)
Nat Rev Clin Oncol.
, vol.10
, Issue.12
, pp. 720-724
-
-
Pusztai, L.1
Hatzis, C.2
Andre, F.3
-
21
-
-
84870695424
-
Methodology for comparative effectiveness research: potential and limitations
-
Korn EL, Freidlin B. Methodology for comparative effectiveness research: potential and limitations. J Clin Oncol. 2012; 30: 4185-7.
-
(2012)
J Clin Oncol.
, vol.30
, pp. 4185-4187
-
-
Korn, E.L.1
Freidlin, B.2
-
22
-
-
33646081767
-
High activity of salvage treatment with biweekly paclitaxel-gemcitabine combination in heavily pretreated breast cancer patients
-
Vici P, Capomolla E, Foggi P, et al. High activity of salvage treatment with biweekly paclitaxel-gemcitabine combination in heavily pretreated breast cancer patients. J Exp Clin Cancer Res. 2006; 25: 39-44.
-
(2006)
J Exp Clin Cancer Res.
, vol.25
, pp. 39-44
-
-
Vici, P.1
Capomolla, E.2
Foggi, P.3
-
23
-
-
79953767581
-
Phase I-II trial of prolonged gemcitabine infusion plus paclitaxel as a biweekly schedule for advanced breast cancer patients pretreated with anthracyclines
-
Vici P, Fabi A, Metro G, et al. Phase I-II trial of prolonged gemcitabine infusion plus paclitaxel as a biweekly schedule for advanced breast cancer patients pretreated with anthracyclines. Cancer Chemother Pharmacol. 2011; 67: 687-93.
-
(2011)
Cancer Chemother Pharmacol.
, vol.67
, pp. 687-693
-
-
Vici, P.1
Fabi, A.2
Metro, G.3
-
24
-
-
50549096593
-
Gemcitabine plus Paclitaxel versus Paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
-
Albain KS, Nag SM, Calderillo-Ruiz G, et al. Gemcitabine plus Paclitaxel versus Paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment. J Clin Oncol. 2008; 26: 3950-7.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 3950-3957
-
-
Albain, K.S.1
Nag, S.M.2
Calderillo-Ruiz, G.3
-
25
-
-
84866850496
-
Treatment options in anthracycline and/or taxane pretreated patients with metastatic breast cancer
-
Pugliano L, de Azambuja E. Treatment options in anthracycline and/or taxane pretreated patients with metastatic breast cancer. Onkologie. 2012; 35: 476-8.
-
(2012)
Onkologie.
, vol.35
, pp. 476-478
-
-
Pugliano, L.1
de Azambuja, E.2
-
26
-
-
0030026360
-
Vinorelbine and mitomycin C in anthracycline-pretreated patients with advanced breast cancer
-
Vici P, Di Lauro L, Carpano S, et al. Vinorelbine and mitomycin C in anthracycline-pretreated patients with advanced breast cancer. Oncology. 1996; 53: 16-8.
-
(1996)
Oncology.
, vol.53
, pp. 16-18
-
-
Vici, P.1
Di Lauro, L.2
Carpano, S.3
-
27
-
-
54749144256
-
A phase II trial of docetaxel and vinorelbine in patients with advanced breast cancer previously treated with anthracyclines
-
Vici P, Di Lauro L, Sergi D, et al. A phase II trial of docetaxel and vinorelbine in patients with advanced breast cancer previously treated with anthracyclines. Oncology. 2008; 75: 175-81.
-
(2008)
Oncology.
, vol.75
, pp. 175-181
-
-
Vici, P.1
Di Lauro, L.2
Sergi, D.3
-
28
-
-
0037445120
-
Are anthracycline-taxane regimens the new standard of care in the treatment of metastatic breast cancer
-
Valero V, Hortobagyi GN. Are anthracycline-taxane regimens the new standard of care in the treatment of metastatic breast cancer? J Clin Oncol. 2003; 21: 959-62.
-
(2003)
J Clin Oncol.
, vol.21
, pp. 959-962
-
-
Valero, V.1
Hortobagyi, G.N.2
-
29
-
-
38049079353
-
Phase II study of weekly albumin-bound paclitaxel for patients with metastatic breast cancer heavily pretreated with taxanes
-
Blum JL, Savin MA, Edelman G, et al. Phase II study of weekly albumin-bound paclitaxel for patients with metastatic breast cancer heavily pretreated with taxanes. Clin Breast Cancer. 2007; 7: 850-6.
-
(2007)
Clin Breast Cancer.
, vol.7
, pp. 850-856
-
-
Blum, J.L.1
Savin, M.A.2
Edelman, G.3
-
30
-
-
34548187738
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer
-
Thomas E, Tabernero J, Fornier M, et al. Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer. J Clin Oncol. 2007; 25: 3399-406.
-
(2007)
J Clin Oncol.
, vol.25
, pp. 3399-3406
-
-
Thomas, E.1
Tabernero, J.2
Fornier, M.3
-
31
-
-
34548157209
-
Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine
-
Perez EA, Lerzo G, Pivot X, et al. Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine. J Clin Oncol. 2007; 25: 3407-14.
-
(2007)
J Clin Oncol.
, vol.25
, pp. 3407-3414
-
-
Perez, E.A.1
Lerzo, G.2
Pivot, X.3
-
32
-
-
84881474908
-
Eribulin mesylate versus ixabepilone in patients with metastatic breast cancer: a randomized Phase II study comparing the incidence of peripheral neuropathy
-
Vahdat LT, Garcia AA, Vogel C, et al. Eribulin mesylate versus ixabepilone in patients with metastatic breast cancer: a randomized Phase II study comparing the incidence of peripheral neuropathy. Breast Cancer Res Treat. 2013; 140: 341-51.
-
(2013)
Breast Cancer Res Treat.
, vol.140
, pp. 341-351
-
-
Vahdat, L.T.1
Garcia, A.A.2
Vogel, C.3
-
33
-
-
33645798077
-
Capecitabine monotherapy: safe and effective treatment for metastatic breast cancer
-
Ershler WB. Capecitabine monotherapy: safe and effective treatment for metastatic breast cancer. Oncologist. 2006; 11: 325-35.
-
(2006)
Oncologist.
, vol.11
, pp. 325-335
-
-
Ershler, W.B.1
-
34
-
-
84878765775
-
Pooled analysis of individual patient data from capecitabine monotherapy clinical trials in locally advanced or metastatic breast cancer
-
Blum JL, Barrios CH, Feldman N, et al. Pooled analysis of individual patient data from capecitabine monotherapy clinical trials in locally advanced or metastatic breast cancer. Breast Cancer Res Treat. 2012; 136: 777-88.
-
(2012)
Breast Cancer Res Treat.
, vol.136
, pp. 777-788
-
-
Blum, J.L.1
Barrios, C.H.2
Feldman, N.3
-
35
-
-
84896955490
-
-
A phase III, open-label, randomized, multicenter study of eribulin mesylate versus capecitabine in patients with locally advanced or metastatic breast cancer previously treated with anthracyclines and taxanes. Presented at: 2012 CTRC-AACR San Antonio Breast Cancer Symposium; December 4-8, 2012; San Antonio, Texas. Abstract S6-6.
-
Kaufman PA, Awada A, Twelves C, et al. A phase III, open-label, randomized, multicenter study of eribulin mesylate versus capecitabine in patients with locally advanced or metastatic breast cancer previously treated with anthracyclines and taxanes. Presented at: 2012 CTRC-AACR San Antonio Breast Cancer Symposium; December 4-8, 2012; San Antonio, Texas. Abstract S6-6.
-
-
-
Kaufman, P.A.1
Awada, A.2
Twelves, C.3
-
36
-
-
84893872824
-
Eribulin mesylate in heavily pretreated metastatic breast cancer patients: current practice in an Italian community hospital
-
Poletti P, Ghilardi V, Livraghi L, Milesi L, Rota Caremoli E, Tondini C. Eribulin mesylate in heavily pretreated metastatic breast cancer patients: current practice in an Italian community hospital. Future Oncol. 2014; 10: 233-9.
-
(2014)
Future Oncol.
, vol.10
, pp. 233-239
-
-
Poletti, P.1
Ghilardi, V.2
Livraghi, L.3
Milesi, L.4
Rota Caremoli, E.5
Tondini, C.6
-
37
-
-
84897015024
-
Activity of eribulin mesylate in heavily pretreated breast cancer granted access via the Cancer Drugs Fund.
-
[Epub ahead of print].
-
Ramaswami R, O'Cathail SM, Brindley JH, Silcocks P, Mahmoud S, Palmieri C. Activity of eribulin mesylate in heavily pretreated breast cancer granted access via the Cancer Drugs Fund. Future Oncol. 2013; [Epub ahead of print].
-
(2013)
Future Oncol.
-
-
Ramaswami, R.1
O'Cathail, S.M.2
Brindley, J.H.3
Silcocks, P.4
Mahmoud, S.5
Palmieri, C.6
-
38
-
-
84877814639
-
Treating breast cancer in the 21st century: emerging biological therapies
-
Tinoco G, Warsch S, Glück S, Avancha K, Montero AJ. Treating breast cancer in the 21st century: emerging biological therapies. J Cancer. 2013; 4: 117-32.
-
(2013)
J Cancer.
, vol.4
, pp. 117-132
-
-
Tinoco, G.1
Warsch, S.2
Glück, S.3
Avancha, K.4
Montero, A.J.5
|