4977-bp mitochondrial DNA deletion in infertile patients with varicocele

Andrologia

Volumn 46, Issue 3, 2014, Pages 258-262

  Gashti, N G ^a   Salehi, Z ^a   Madani, A H ^b   Dalivandan, S T ^a  

^a UNIVERSITY OF GUILAN   (Iran)

^b GUILAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Male infertility; MtDNA deletion; Oxidative stress; ROS; Varicocele

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; GENE DELETION; GENE FREQUENCY; HUMAN; IRAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; POLYMERASE CHAIN REACTION; SEMEN ANALYSIS; SPERM; SPERMATOZOON; VARICOCELE; YOUNG ADULT; CASE CONTROL STUDY; COMPLICATION; GENETICS; INFERTILITY, MALE; METABOLISM;

ADULT; CASE-CONTROL STUDIES; DNA, MITOCHONDRIAL; HUMANS; INFERTILITY, MALE; IRAN; MALE; SEQUENCE DELETION; SPERMATOZOA; VARICOCELE; YOUNG ADULT;

EID: 84896889988     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/and.12073     Document Type: Article

References (22)

1. Agarwal A, Sharma RK, Desai NR, Prabakaran S, Tavares A, Sabanegh E (2009) Role of oxidative stress in pathogenesis of varicocele and infertility. Urology 73:461-469.
2. Allamaneni SS, Naughton CK, Sharma RK, Thomas AJ, Agarwal A (2004) Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size. Fertil Steril 82:1684-1686.
3. Benoff S, Hurley IR, Barcia M, Mandel FS, Cooper GW, Hershlag A (1997) A potential role for cadmium in the etiology of varicocele-associated infertility. Fertil Steril 67:336-347.
4. Chen SS, Chang LS, Chen HW, Wei YH (2002) Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele. Hum Reprod 17:718-725.
5. Chen SS, Huang WJ, Chang LS, Wei YH (2004) 8-Hydroxy-2-deoxyguanosine in leukocyte DNA of spermatic vein as a biomarker of oxidative stress in patients with varicocele. J Urol 172:1418-1421.
6. Dada R, Kumar R, Shamsi MB, Sidhu T, Mitra A, Singh S, Kumar R, Sharma RS, Gupta SK, Gupta NP (2007) Azoospermia factor deletions in varicocele cases with severe oligozoospermia. Indian J Med Sci 61:505-510.
7. Folgero T, Bertheussen K, Lindal S, Torbergsen T, Oian P (1993) Mitochondrial disease and reduced sperm motility. Hum Reprod 8:1863-1868.
8. French DB, Desai NR, Agarwal A (2008) Varicocele repair: does it still have a role in infertility treatment? Curr Opin Obstet Gynecol 20:269-274.
9. Ishikawa T, Kondo Y, Yamaguchi K, Sakamoto Y, Fujisawa M (2008) Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia. BJU Int 101:216-218.
10. Kao SH, Chao HT, Wei YH (1998) Multiple deletions of mitochondrial DNA are associated with the decline of motility and fertility of human spermatozoa. Mol Hum Reprod 4:657-666.
11. Klein EA, Platz EA, Thompson IM (2007) Abnormalities of the testes and scrotum and their surgical management. In: Campbell-Walsh Urology, 9th edn. Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA (eds). Saunders, Philadelphia, pp 3761-3798.
12. Lee HC, Wei YH (1997) Mutation and oxidative damage of mitochondrial DNA and defective turnover of mitochondria in human aging. J Formos Med Assoc 96:718-770.
13. Levinger U, Gornish M, Gat Y, Bachar GN (2007) Is varicocele prevalence increasing with age? Andrologia 39:77-80.
14. Petros JA, Baumann AK, Ruiz-Pesini E, Amin MB, Sun CQ, Hall J, Lim S, Issa MM, Flanders WD, Hosseini SH, Marshall FF, Wallace DC (2005) mtDNA mutations increase tumorigenicity in prostate cancer. Proc Natl Acad Sci USA 102:719-724.
15. Sawyer E, Van Houten B (1999) Repair of DNA damage in mitochondria. Mutat Res 434:161-176.
16. Shamsi MB, Kumar R, Bhatt A, Bamezai RN, Kumar R, Gupta NP, Das TK, Dada R (2008) Mitochondrial DNA mutations in etiopathogenesis of male infertility. Indian J Urol 24:150-154.
17. Shen HM, Chia SE, Ong CN (1999) Evaluation of oxidative DNA damage in human sperm and its association with male infertility. J Androl 20:718.
18. Spiropoulos J, Turnbull DM, Chinnery PF (2002) Can mitochondrial DNA mutations cause sperm dysfunction? Mol Hum Reprod 8:719-721.
19. St. John JC, Sakkas D, Barratt CL (2000) A role for mitochondrial DNA and sperm survival. J Androl 21:189-199.
20. Thayer RE, Wittock R, Parr R, Zullo S, Birch-Machin MA (2003) A maternal line study investigating the 4977-bp mitochondrial DNA deletion. Exp Gerontol 38:567-571.
21. World Health Organization (1999) WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. Cambridge University Press, Cambridge.
22. Zeviani M, Moraes CT, DiMauro S, Nakase H, Bonilla E, Schon EA, Rowland LP (1988) Deletions of mitochondrial DNA in Kearns-Sayre syndrome. Neurology 38:1339-1346.