Sources of HIV incidence among stable couples in sub-Saharan Africa

Journal of the International AIDS Society

Volumn 17, Issue , 2014, Pages

  Chemaitelly, Hiam ^a   Awad, Susanne F ^a   Shelton, James D ^b   Abu Raddad, Laith J ^a,c,d  

^a WEILL CORNELL MEDICAL COLLEGE   (Qatar)

^b UNITED STATES AGENCY FOR INTERNATIONAL DEVELOPMENT   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d USA   (United States)

Author keywords

Demographic and health surveys; HIV incidence; Mathematical model; Sources of infection; Stable couples; Sub Saharan Africa

Indexed keywords

AFRICA SOUTH OF THE SAHARA; ARTICLE; COHORT ANALYSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; VIRUS TRANSMISSION;

DEMOGRAPHIC AND HEALTH SURVEYS; HIV INCIDENCE; MATHEMATICAL MODEL; SOURCES OF INFECTION; STABLE COUPLES; SUB-SAHARAN AFRICA;

AFRICA SOUTH OF THE SAHARA; FEMALE; HIV INFECTIONS; HIV SERONEGATIVITY; HIV SEROPOSITIVITY; HUMANS; INCIDENCE; MALE; MODELS, THEORETICAL; SPOUSES;

EID: 84896884960     PISSN: None     EISSN: 17582652     Source Type: Journal    
DOI: 10.7448/IAS.17.1.18765     Document Type: Article

References (53)

1. Chemaitelly H, Cremin I, Shelton JD, Hallett TB, Abu-Raddad LJ. Distinct HIV discordancy patterns by epidemic size in stable sexual partnerships in sub-Saharan Africa. Sex Transm Infect. 2012;88:51-7.
2. Guthrie BL, De Bruyn G, Farquhar C. HIV-1-discordant couples in sub-Saharan Africa: explanations and implications for high rates of discordancy. Curr HIV Res. 2007;5(4):416-29. (Pubitemid 47040483)
3. Lingappa JR, Lambdin B, Bukusi EA, Ngure K, Kavuma L, Inambao M, et al. Regional differences in prevalence of HIV-1 discordance in Africa and enrollment of HIV-1 discordant couples into an HIV-1 prevention trial. PLoS One. 2008;3(1):e1411.
4. Bunnell R, Opio A, Musinguzi J, Kirungi W, Ekwaru P, Mishra V, et al. HIV transmission risk behavior among HIV-infected adults in Uganda: results of a nationally representative survey. AIDS. 2008;22(5):617-24. (Pubitemid 351640594)
5. Baryarama F, Bunnell R, McFarland W, Hudes ES, Neilands TB, Ransom RL, et al. Estimating HIV incidence in voluntary counseling and testing clients in Uganda (1992-2003). J Acquir Immune Defic Syndr. 2007;44(1):99-105. (Pubitemid 46052227)
6. Abdool Karim Q, Abdool Karim SS, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329(5996):1168-74.
7. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493-505.
8. Thigpen MC, Kebaabetswe PM, Paxton LA, Smith DK, Rose CE, Segolodi TM, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012;367(5):423-34.
9. Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367(5):399-410.
10. UNAIDS, WHO, UNICEF. Global HIV/AIDS response: epidemic update and health sector progress towards universal access. Geneva: World Health Organization; 2011.
11. UNAIDS. UNAIDS world AIDS day report. Geneva, Switzerland: UNAIDS; 2012.
12. World Health Organization. Guidance on couples HIV testing and counselling including antiretroviral therapy for treatment and prevention in serodiscordant couples. Geneva: Department of HIV/AIDS- World Health Organization; 2012.
13. Chemaitelly H, Shelton JD, Hallett TB, Abu-Raddad LJ. Only a fraction of new HIV infections occur within identifiable stable discordant couples in sub-Saharan Africa. AIDS. 2013;27(2):251-60.
14. Chemaitelly H, Abu-Raddad LJ. External infections contribute minimally to HIV incidence among HIV sero-discordant couples in sub-Saharan Africa. Sex Transm Infect. 2013;89(2):138-41.
15. Chemaitelly H, Awad S, Abu-Raddad LJ. The risk of HIV transmission within HIV-1 sero-discordant couples appears to vary across sub-Saharan Africa. Epidemics. 2014;6:1-9.
16. MEASURE DHS. Demographic and health surveys [Internet]. Calverton: ICF Macro; 2012 [updated 2012; cited 2010 May 19]. Available from: http://www.measuredhs.com/data/available-datasets.cfm
17. United Nations Department of Economic and Social Affairs, Population Division, Population Estimates and Projections Section. World population prospects: the 2010 revision population database. 2010 [cited 2011 Sep 16]. Available from: http://esa.un.org/unpd/wpp/unpp/panel-population.htm.
18. Rutstein S, Rojas G. Guide to DHS statistics. Calverton, MD: ORC Macro; 2006.
19. Demographic and Health Surveys. Dataset FAQs: dataset indicators [Internet]. MEASURE DHS. [cited 2011 May 28]. Available from: http://www.measuredhs.com/accesssurveys/dataset-faqs.cfm
20. UNAIDS. HIV estimates with uncertainty bounds 1990-2011. UNAIDS global report 2012 [Internet]. 2011 [updated 2011; cited 2011 Dec 5]. Available from: http://www.unaids.org/en/resources/campaigns/20121120-globalreport2012/ globalreport/
21. Nelson KE, Williams CM. Infectious disease epidemiology: theory and practice. 2nd ed. Sudbury, MA: Jones and Bartlett; 2007. xvi, 1207 p.
22. Wawer MJ, Gray RH, Sewankambo NK, Serwadda D, Li X, Laeyendecker O, et al. Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis. 2005;191(9):1403-9. (Pubitemid 40563350)
23. Celum C, Wald A, Lingappa JR, Magaret AS, Wang RS, Mugo N, et al. Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2. N Engl J Med. 2010;362(5):427-39.
24. Hughes JP, Baeten JM, Lingappa JR, Magaret AS, Wald A, de Bruyn G, et al. Determinants of Per-Coital-Act HIV-1 infectivity among African HIV-1-serodiscordant couples. J Infect Dis. 2012;205(3):358-65.
25. Pinkerton SD. Probability of HIV transmission during acute infection in Rakai, Uganda. AIDS Behav. 2008;12(5):677-84.
26. Hughes JP. Personal communication. 2010.
27. Eyawo O, de Walque D, Ford N, Gakii G, Lester RT, Mills EJ. HIV status in discordant couples in sub-Saharan Africa: a systematic review and meta-analysis. Lancet Infect Dis. 2010;10(11):770-7.
28. Weller S, Davis K. Condom effectiveness in reducing heterosexual HIV transmission. Cochrane Database Syst Rev. 2001;(3):CD003255.
29. Weiss HA, Halperin D, Bailey RC, Hayes RJ, Schmid G, Hankins CA. Male circumcision for HIV prevention: from evidence to action? AIDS. 2008;22(5):567-74. (Pubitemid 351640589)
30. Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med. 2005;2(11):e298.
31. Bailey RC, Moses S, Parker CB, Agot K, Maclean I, Krieger JN, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369(9562):643-56. (Pubitemid 46281312)
32. Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369(9562):657-66.
33. Gray R, Ssempiija V, Shelton J, Serwadda D, Nalugoda F, Kagaayi J, et al. The contribution of HIV-discordant relationships to new HIV infections in Rakai, Uganda. AIDS. 2011;25(6):863-5.
34. Bellan SE, Fiorella KJ, Melesse DY, Getz WM, Williams BG, Dushoff J. Extra-couple HIV transmission in sub-Saharan Africa: a mathematical modelling study of survey data. Lancet. 2013;381(9877):1561-9.
35. Hallett TB, Zaba B, Todd J, Lopman B, Mwita W, Biraro S, et al. Estimating incidence from prevalence in generalised HIV epidemics: methods and validation. PLoS Med. 2008;5(4):e80.
36. Gouws E, Williams BG, Sheppard HW, Enge B, Karim SA. High incidence of HIV-1 in South Africa using a standardized algorithm for recent HIV seroconversion. J Acquir Immune Defic Syndr. 2002;29(5):531-5. (Pubitemid 34456346)
37. Monasch R, Mahy M. Young people: the centre of the HIV epidemic. World Health Organ Tech Rep Ser. 2006;938:15-41. (Pubitemid 46931516)
38. Granich RM, Gilks CF, Dye C, De Cock KM, Williams BG. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009;373(9657):48-57.
39. World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Geneva: World Health Organization; 2013.
40. Kilmarx PH, Mutasa-Apollo T. Patching a leaky pipe: the cascade of HIV care. Curr Opin HIV AIDS. 2013;8(1):59-64.
41. Mishra V, Barrere B, Hong R, Khan S. Evaluation of bias in HIV seroprevalence estimates from national household surveys. Sex Transm Infect. 2008;84(Suppl 1):63-70.
42. Abu-Raddad LJ, Magaret AS, Celum C, Wald A, Longini IM, Jr, Self SG, et al. Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa. PLoS One. 2008;3(5):e2230.
43. Korenromp EL, de Vlass SJ, Nagelkerke NJ, Habbema JD. Estimating the magnitude of STD cofactor effects on HIV transmission: how well can it be done? Sex Transm Dis. 2001;28(11):613-21. (Pubitemid 33055103)
44. Abu-Raddad LJ, Patnaik P, Kublin JG. Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa. Science. 2006;314(5805):1603-6. (Pubitemid 44907155)
45. Abu-Raddad LJ, Barnabas RV, Janes H, Weiss HA, Kublin JG, Longini IM, Jr, et al. Have the explosive HIV epidemics in sub-Saharan Africa been driven by higher community viral load? AIDS. 2013;27960:981-9. Epub 2012/12/01.
46. Kaul R, Cohen CR, Chege D, Yi TJ, Tharao W, McKinnon LR, et al. Biological factors that may contribute to regional and racial disparities in HIV prevalence. Am J Reprod Immunol. 2011;65(3):317-24.
47. Novitsky V, Woldegabriel E, Kebaabetswe L, Rossenkhan R, Mlotshwa B, Bonney C, et al. Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection. J Acquir Immune Defic Syndr. 2009;50(1):65-76.
48. Novitsky V, Ndung'u T, Wang R, Bussmann H, Chonco F, Makhema J, et al. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS. 2011;25(12):1515-22.
49. Hollingsworth TD, Anderson RM, Fraser C. HIV-1 transmission, by stage of infection. J Infect Dis. 2008;198(5):687-93.
50. Powers KA, Ghani AC, Miller WC, Hoffman IF, Pettifor AE, Kamanga G, et al. The role of acute and early HIV infection in the spread of HIV and implications for transmission prevention strategies in Lilongwe, Malawi: a modelling study. Lancet. 2011;378(9787):256-68.
51. Boily MC, Baggaley RF, Wang L, Masse B, White RG, Hayes RJ, et al. Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies. Lancet Infect Dis. 2009;9(2):118-29.
52. Cohen MS, Dye C, Fraser C, Miller WC, Powers KA, Williams BG. HIV treatment as prevention: debate and commentary - will early infection compromise treatment-as-prevention strategies? PLoS Med. 2012;9(7):e1001232.
53. Hallett TB, Stover J, Mishra V, Ghys PD, Gregson S, Boerma T. Estimates of HIV incidence from household-based prevalence surveys. AIDS. 2010;24(1):147-52.