Injectable, self-gelling, biodegradable, and immunomodulatory DNA hydrogel for antigen delivery

Journal of Controlled Release

Volumn 180, Issue 1, 2014, Pages 25-32

  Nishikawa, Makiya ^a   Ogawa, Kohei ^a   Umeki, Yuka ^a   Mohri, Kohta ^a   Kawasaki, Yohji ^a   Watanabe, Hiroshi ^a   Takahashi, Natsuki ^a   Kusuki, Eri ^a   Takahashi, Rei ^b   Takahashi, Yuki ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

Author keywords

Antigen; Controlled release; CpG motif; Hydrogel; Immune cell; Self gelling

Indexed keywords

COMPLETE FREUND'S ADJUVANTS; CONTROLLED RELEASE; CPG MOTIF; IMMUNE CELLS; INJECTABLE HYDROGELS; INTRADERMAL INJECTION; PHYSIOLOGICAL CONDITION; SELF-GELLING;

ANTIGENS; BIOCOMPATIBILITY; DNA; DNA SEQUENCES; GELATION; IMMUNE SYSTEM; NANOSYSTEMS;

HYDROGELS;

ALUMINUM POTASSIUM SULFATE; ANTIGEN; CYTOSINE PHOSPHATE GUANINE DINUCLEOTIDE; DINUCLEOTIDE; DNA; FREUND ADJUVANT; HEXAPODNA; INORGANIC SALT; OVALBUMIN; PENTADNA; POLYPODNA; TETRADNA; TOLL LIKE RECEPTOR 9; TRIDNA; UNCLASSIFIED DRUG; DELAYED RELEASE FORMULATION; HYDROGEL; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA STRAND; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; HYDROGEL; IMMUNE RESPONSE; IMMUNOMODULATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; ADMINISTRATION AND DOSAGE; ANIMAL; C57BL MOUSE; CHEMISTRY; CHICKEN; CPG ISLAND; DELAYED RELEASE FORMULATION; IMMUNOLOGY; INJECTION; PHARMACOKINETICS; PHARMACOLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS; CHICKENS; CPG ISLANDS; DELAYED-ACTION PREPARATIONS; DNA; HYDROGEL; INJECTIONS; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; OVALBUMIN;

EID: 84896881766     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.02.001     Document Type: Article

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