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Volumn 15, Issue 3, 2014, Pages 1171-1176

Aberrant methylation of RASSF2A in tumors and plasma of patients with epithelial ovarian cancer

Author keywords

Epithelial ovarian cancer; Hypermethylation; Plasma; RASSF2A

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; MESSENGER RNA; RASSF2 PROTEIN, HUMAN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

EID: 84896862318     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.3.1171     Document Type: Article
Times cited : (40)

References (39)
  • 1
    • 0035932393 scopus 로고    scopus 로고
    • Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours
    • Agathanggelous A, Honorio S, Macartney DP, et al. (2001). Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. Oncogene, 20, 1509-18.
    • (2001) Oncogene , vol.20 , pp. 1509-1518
    • Agathanggelous, A.1    Honorio, S.2    Macartney, D.P.3
  • 2
    • 22344435817 scopus 로고    scopus 로고
    • The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer
    • Akino K, Toyota M, Suzuki H, et al (2005). The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. Gastroenterology, 129, 156-69.
    • (2005) Gastroenterology , vol.129 , pp. 156-169
    • Akino, K.1    Toyota, M.2    Suzuki, H.3
  • 3
    • 0242509115 scopus 로고    scopus 로고
    • Ovarian cancer: changes in patterns at diagnosis and relative survival over the last three decades
    • Barnholtz-Sloan JS, Schwartz AG, Qureshi F, et al (2003). Ovarian cancer: changes in patterns at diagnosis and relative survival over the last three decades. Am J Obstet Gynecol, 189, 1120-7.
    • (2003) Am J Obstet Gynecol , vol.189 , pp. 1120-1127
    • Barnholtz-Sloan, J.S.1    Schwartz, A.G.2    Qureshi, F.3
  • 4
    • 84879252959 scopus 로고    scopus 로고
    • Aberrant promoter methylation of the RASSF1A and APC genes in epithelial ovarian carcinoma development
    • Bhagat R, Chadaga S, Premalata CS, et al (2012). Aberrant promoter methylation of the RASSF1A and APC genes in epithelial ovarian carcinoma development. Cell Oncol, 35, 473-9.
    • (2012) Cell Oncol , vol.35 , pp. 473-479
    • Bhagat, R.1    Chadaga, S.2    Premalata, C.S.3
  • 5
    • 81155123078 scopus 로고    scopus 로고
    • Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer
    • BonDurant AE, Huang Z, Whitaker RS, et al (2011). Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer. Gynecol Oncol, 123, 581-7.
    • (2011) Gynecol Oncol , vol.123 , pp. 581-587
    • BonDurant, A.E.1    Huang, Z.2    Whitaker, R.S.3
  • 6
    • 0027382941 scopus 로고
    • Cancer of the ovary
    • Cannistra SA. (1993). Cancer of the ovary. N Engl Med, 329, 1550-9.
    • (1993) N Engl Med , vol.329 , pp. 1550-1559
    • Cannistra, S.A.1
  • 7
    • 33644822879 scopus 로고    scopus 로고
    • Aberrant hypermethylation of RASSF1A promoter in ovarian borderline tumors and carcinomas
    • Choi YL, Kang SY, Shin YK, et al (2006). Aberrant hypermethylation of RASSF1A promoter in ovarian borderline tumors and carcinomas. Virchows Arch, 448, 331-6.
    • (2006) Virchows Arch , vol.448 , pp. 331-336
    • Choi, Y.L.1    Kang, S.Y.2    Shin, Y.K.3
  • 8
    • 0035031279 scopus 로고    scopus 로고
    • Methylation matters
    • Costello JF, Plass C. (2001). Methylation matters. J Med Gent, 38, 285-303.
    • (2001) J Med Gent , vol.38 , pp. 285-303
    • Costello, J.F.1    Plass, C.2
  • 9
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, et al (2000). Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet, 25, 315-9.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3
  • 10
    • 0035300429 scopus 로고    scopus 로고
    • Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers
    • Dammann R, Yang G, Pfeifer GP. (2001). Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res, 61, 3105-9.
    • (2001) Cancer Res , vol.61 , pp. 3105-3109
    • Dammann, R.1    Yang, G.2    Pfeifer, G.P.3
  • 11
    • 84872685468 scopus 로고    scopus 로고
    • Lack of significance of the BRCA2 promoter methylation status in different genotypes of the MTHFR a1298c polymorphism in ovarian cancer cases in Iran
    • Darehdori AS, Dastjerdi MN, Dahim H, et al (2012). Lack of significance of the BRCA2 promoter methylation status in different genotypes of the MTHFR a1298c polymorphism in ovarian cancer cases in Iran. Asian Pac J Cancer Prev, 13, 1833-6.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 1833-1836
    • Darehdori, A.S.1    Dastjerdi, M.N.2    Dahim, H.3
  • 12
    • 84885450967 scopus 로고    scopus 로고
    • Effect of 5-aza-2'-deoxycytidine on cell proliferation of non-small cell lung cancer cell line A549 cells and expression of the TFPI-2 gene
    • Dong YQ, Liang JS, Zhu SB, et al (2013). Effect of 5-aza-2'-deoxycytidine on cell proliferation of non-small cell lung cancer cell line A549 cells and expression of the TFPI-2 gene. Asian Pac J Cancer Prev, 14, 4421-6.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 4421-4426
    • Dong, Y.Q.1    Liang, J.S.2    Zhu, S.B.3
  • 13
    • 28644450906 scopus 로고    scopus 로고
    • RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
    • Endoh M, Tamura G, Honda T, et al (2005). RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer. Br J Cancer, 93, 1395-9.
    • (2005) Br J Cancer , vol.93 , pp. 1395-1399
    • Endoh, M.1    Tamura, G.2    Honda, T.3
  • 14
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. (2003). Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med, 349, 2042-54.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 15
    • 20544445183 scopus 로고    scopus 로고
    • CpG island promoter hypermethylation of a novel Ras effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutuation
    • Hesson LB, Wilson R, Morton D, et al (2005). CpG island promoter hypermethylation of a novel Ras effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutuation. Oncogene, 24, 3987-94.
    • (2005) Oncogene , vol.24 , pp. 3987-3994
    • Hesson, L.B.1    Wilson, R.2    Morton, D.3
  • 16
    • 4644271551 scopus 로고    scopus 로고
    • Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients
    • Ibanez de Caceres I, Battagli C, Esteller M, et al (2004). Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients. Cancer Res, 64, 6476-81.
    • (2004) Cancer Res , vol.64 , pp. 6476-6481
    • Ibanez de Caceres, I.1    Battagli, C.2    Esteller, M.3
  • 17
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. (2007). The epigenomics of cancer. Cell, 128, 683-92.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 18
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones PA, Laird PW. (1999). Cancer epigenetics comes of age. Nat Genet, 21, 163-7.
    • (1999) Nat Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 19
    • 0017360626 scopus 로고    scopus 로고
    • Free DNA in the serum of cancer patients and the effect of therapy
    • Leon SA, Shapiro B, Sklaroff DM, et al (1997). Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res, 37, 646-50.
    • (1997) Cancer Res , vol.37 , pp. 646-650
    • Leon, S.A.1    Shapiro, B.2    Sklaroff, D.M.3
  • 20
    • 44949106316 scopus 로고    scopus 로고
    • Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carciongenesis
    • Liao X, Siu MK, Chan KY, et al (2008). Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carciongenesis. Int J Cancer, 123, 296-302.
    • (2008) Int J Cancer , vol.123 , pp. 296-302
    • Liao, X.1    Siu, M.K.2    Chan, K.Y.3
  • 21
    • 84882582854 scopus 로고    scopus 로고
    • Associations between RASSF1A promoter methylation and NSCLC: a metaanalysis of published data
    • Liu WJ, Tan XH, Guo BP, et al (2013). Associations between RASSF1A promoter methylation and NSCLC: a metaanalysis of published data. Asian Pac J Cancer Prev, 14, 3719-24.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 3719-3724
    • Liu, W.J.1    Tan, X.H.2    Guo, B.P.3
  • 22
    • 23044466227 scopus 로고    scopus 로고
    • Promoter hypermethylation profile of ovarian epithelial neoplasms
    • Makarla PB, Saboorian MH, Ashfaq R, et al (2005). Promoter hypermethylation profile of ovarian epithelial neoplasms. Clin Cancer Res, 11, 5365-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 5365-5369
    • Makarla, P.B.1    Saboorian, M.H.2    Ashfaq, R.3
  • 23
    • 68849104515 scopus 로고    scopus 로고
    • Clinicopathological implications of inactivation of RASSF1A in serous epithelial ovarian cancers
    • Ma L, Guo Q, Ma Y, et al (2009). Clinicopathological implications of inactivation of RASSF1A in serous epithelial ovarian cancers. Eur J Gynaecol Oncol, 30, 370-4.
    • (2009) Eur J Gynaecol Oncol , vol.30 , pp. 370-374
    • Ma, L.1    Guo, Q.2    Ma, Y.3
  • 24
    • 49349109183 scopus 로고    scopus 로고
    • Cytopalsmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer
    • Maruyuma R, Akino K, Toyata M, et al (2008). Cytopalsmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer. Carcinogenesis, 29, 1312-8.
    • (2008) Carcinogenesis , vol.29 , pp. 1312-1318
    • Maruyuma, R.1    Akino, K.2    Toyata, M.3
  • 25
    • 0037098039 scopus 로고    scopus 로고
    • The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation
    • Mutskov VJ, Farrell CM, Wade PA, et al (2002). The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. Genes Dev, 16, 1540-54.
    • (2002) Genes Dev , vol.16 , pp. 1540-1554
    • Mutskov, V.J.1    Farrell, C.M.2    Wade, P.A.3
  • 26
    • 33845451110 scopus 로고    scopus 로고
    • Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers
    • Park HW, Kang HC, Kim IJ, et al (2007). Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers. Int J Cancer, 120, 7-12.
    • (2007) Int J Cancer , vol.120 , pp. 7-12
    • Park, H.W.1    Kang, H.C.2    Kim, I.J.3
  • 27
    • 0015421011 scopus 로고
    • Serum DNA levels in patients with malignant disease
    • Perlin E, Moquin RB. (1972). Serum DNA levels in patients with malignant disease. Am J Clin Pathol, 58, 601-2.
    • (1972) Am J Clin Pathol , vol.58 , pp. 601-602
    • Perlin, E.1    Moquin, R.B.2
  • 28
    • 79958795295 scopus 로고    scopus 로고
    • SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated
    • Qiu H, Zhu J, Yu J, et al (2011). SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated. Asian Pac J Cancer Prev, 12, 791-5.
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 791-795
    • Qiu, H.1    Zhu, J.2    Yu, J.3
  • 29
    • 0036847546 scopus 로고    scopus 로고
    • Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women
    • Rathi A, Virmani AK, Schorge JO, et al (2002). Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women. Clin Cancer Res, 8, 3324-31.
    • (2002) Clin Cancer Res , vol.8 , pp. 3324-3331
    • Rathi, A.1    Virmani, A.K.2    Schorge, J.O.3
  • 30
    • 70349673155 scopus 로고    scopus 로고
    • RASSF2A promoter methylation in hepatitis B virus-related hepatocellular cancinogenesis and its correlation with elevated serum α-fetoprotein level
    • Ren J, He W, Zhang R, et al (2009). RASSF2A promoter methylation in hepatitis B virus-related hepatocellular cancinogenesis and its correlation with elevated serum α-fetoprotein level. J Huazhong Univ Sci Technol [Med Sci], 29, 309-12.
    • (2009) J Huazhong Univ Sci Technol [Med Sci] , vol.29 , pp. 309-312
    • Ren, J.1    He, W.2    Zhang, R.3
  • 31
    • 70349174971 scopus 로고    scopus 로고
    • The RASSF proteins in cancer; from epigenetic silencing to functional characterization
    • Richter AM, Pfeifer GP, Dammann RH. (2009). The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta, 1796, 114-28.
    • (2009) Biochim Biophys Acta , vol.1796 , pp. 114-128
    • Richter, A.M.1    Pfeifer, G.P.2    Dammann, R.H.3
  • 32
    • 73449083120 scopus 로고    scopus 로고
    • Long-term survival after fertility-sparing surgery for epithelial ovarian cancer
    • Schlaerth AC, Chi DS, Poynor EA, et al (2009). Long-term survival after fertility-sparing surgery for epithelial ovarian cancer. Int J Gynecol Cancer, 19, 1199-204.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 1199-1204
    • Schlaerth, A.C.1    Chi, D.S.2    Poynor, E.A.3
  • 34
    • 0036675204 scopus 로고    scopus 로고
    • Normal ras genes: their onco-suppressor and pro-apoptotic functions
    • Spandidos DA, Sourvinos G, Tsatsanis C, et al (2002). Normal ras genes: their onco-suppressor and pro-apoptotic functions. Int J Oncol, 21, 237-41.
    • (2002) Int J Oncol , vol.21 , pp. 237-241
    • Spandidos, D.A.1    Sourvinos, G.2    Tsatsanis, C.3
  • 35
    • 0041845273 scopus 로고    scopus 로고
    • RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor
    • Vos MD, Ellis CA, Elam C, et al (2003). RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. J. Biol Chem, 278, 28045-51.
    • (2003) J. Biol Chem , vol.278 , pp. 28045-28051
    • Vos, M.D.1    Ellis, C.A.2    Elam, C.3
  • 36
    • 33646725688 scopus 로고    scopus 로고
    • Prognostic DNA methylation biomarkers in ovarian cancer
    • Wei SH, Balch C, Paik HH, et al (2006). Prognostic DNA methylation biomarkers in ovarian cancer. Clin Cancer Res, 12, 2788-94.
    • (2006) Clin Cancer Res , vol.12 , pp. 2788-2794
    • Wei, S.H.1    Balch, C.2    Paik, H.H.3
  • 37
    • 0035888160 scopus 로고    scopus 로고
    • Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas
    • Yoon JH, Dammann R, Pfeifer GP. (2001). Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas. Int J Cancer, 94, 212-7.
    • (2001) Int J Cancer , vol.94 , pp. 212-217
    • Yoon, J.H.1    Dammann, R.2    Pfeifer, G.P.3
  • 38
    • 33845400874 scopus 로고    scopus 로고
    • Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma
    • Zhang Z, Sun D, Van do N, et al (2007). Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. Int J Cancer, 120, 32-8.
    • (2007) Int J Cancer , vol.120 , pp. 32-38
    • Zhang, Z.1    Sun, D.2    Van do, N.3
  • 39
    • 85008368734 scopus 로고    scopus 로고
    • A multiple methylationsepcific PCR assay for the detection of early-stage ovarian cancer using cell-free serum DNA
    • Zhang Q, Hu G, Yang Q, et al (2013). A multiple methylationsepcific PCR assay for the detection of early-stage ovarian cancer using cell-free serum DNA. Gynecol Oncol, 4, 01-8.
    • (2013) Gynecol Oncol , vol.4 , pp. 01-08
    • Zhang, Q.1    Hu, G.2    Yang, Q.3


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