NAD+ administration decreases doxorubicin-induced liver damage of mice by enhancing antioxidation capacity and decreasing DNA damage

Chemico-Biological Interactions

Volumn 212, Issue 1, 2014, Pages 65-71

  Wang, Ban ^a   Ma, Yingxin ^a   Kong, Xiaoni ^a   Ding, Xianting ^a   Gu, Hongchen ^a   Chu, Tianqing ^a   Ying, Weihai ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Antioxidation; Apoptosis; Doxorubicin; Hepatotoxicity

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CASPASE 3; DOUBLE STRANDED DNA; DOXORUBICIN; GLUTATHIONE; GLUTATHIONE REDUCTASE; HISTONE H2AX; NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOPHAGY; BODY WEIGHT; CASPASE ASSAY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME MECHANISM; IMMUNOHISTOCHEMISTRY; LIVER FUNCTION; LIVER INJURY; LIVER TOXICITY; LIVER WEIGHT; MALE; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION;

ANTIOXIDATION; APOPTOSIS; DOXORUBICIN; HEPATOTOXICITY; NAD(+);

ACETYLCYSTEINE; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BODY WEIGHT; CYTOPROTECTION; DNA DAMAGE; DOXORUBICIN; LIVER; MALE; MICE; MICE, INBRED ICR; NAD; ORGAN SIZE;

EID: 84896858398     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.01.013     Document Type: Article

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