Neuroimmune activation and myelin changes in adolescent rats exposed to high-dose alcohol and associated cognitive dysfunction: A review with reference to human adolescent drinking

Alcohol and Alcoholism

Volumn 49, Issue 2, 2014, Pages 187-192

  Pascual, María ^a   Pla, Antoni ^a   Miñarro, José ^b   Guerri, Consuelo ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALCOHOL; CYCLOOXYGENASE 2; CYCLOPHILIN A; HIGH MOBILITY GROUP B1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MESSENGER RNA; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL EXPERIMENT; BEHAVIOR DISORDER; BINGE DRINKING; BRAIN CORTEX; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS CALLOSUM; DEMYELINATION; DRINKING BEHAVIOR; DRUG DEPENDENCE; GENE EXPRESSION; HIGH RISK BEHAVIOR; HIPPOCAMPUS; IMPULSIVENESS; INNATE IMMUNITY; MYELINATION; NEOCORTEX; NERVE CELL PLASTICITY; NERVOUS SYSTEM INFLAMMATION; NEUROIMMUNOLOGY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; REVIEW; SIGNAL TRANSDUCTION; SUBSTANCE ABUSE; UPREGULATION; WHITE MATTER; WORKING MEMORY;

ADOLESCENT; ALCOHOL DRINKING; ANIMALS; COGNITION DISORDERS; ETHANOL; GENE EXPRESSION; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; MYELIN SHEATH; PREFRONTAL CORTEX; RATS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84896850046     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agt164     Document Type: Review

References (45)

1. Alfonso-Loeches S, Pascual-Lucas M, Blanco AM et al. (2010) Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage. J Neurosci 30:8285-95.
2. Alfonso-Loeches S, Pascual M, Gomez-Pinedo U et al. (2012) Toll-like receptor 4 participates in the myelin disruptions associated with chronic alcohol abuse. Glia 60:948-64.
3. Alfonso-Loeches S, Pascual M, Guerri C. (2013) Gender differences in alcohol-induced neurotoxicity and brain damage. Toxicology 311:27-34.
4. Bava S, Jacobus J, Mahmood O et al. (2009) Neurocognitive correlates of white matter quality in adolescent substance users. Brain Cogn 72:347-54.
5. Bava S, Jacobus J, Thayer RE et al. (2013) Longitudinal changes in white matter integrity among adolescent substance users. Alcohol Clin Exp Res 37(Suppl 1):E181-9.
6. Blakemore SJ. (2008) The social brain in adolescence. Nat Rev Neurosci 9:267-77.
7. Ceccarelli I, Della Seta D, Fiorenzani P et al. (2007) Estrogenic chemicals at puberty change ERalpha in the hypothalamus of male and female rats. Neurotoxicol Teratol 29:108-15.
8. Crews FT, Braun CJ, Hoplight B et al. (2000) Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats. Alcohol Clin Exp Res 24: 1712-23.
9. De Bellis MD, Narasimhan A, Thatcher DL et al. (2005) Prefrontal cortex, thalamus, and cerebellar volumes in adolescents and young adults with adolescent-onset alcohol use disorders and comorbid mental disorders. Alcohol Clin Exp Res 29:1590-600.
10. DeWit DJ, Adlaf EM, Offord DR et al. (2000) Age at first alcohol use: a risk factor for the development of alcohol disorders. Am J Psychiatry 157:745-50.
11. Fernandez-Lizarbe S, Pascual M, Guerri C. (2009) Critical role of TLR4 response in the activation of microglia induced by ethanol. J Immunol 183:4733-44.
12. Fernandez-Lizarbe S, Montesinos J, Guerri C. (2013) Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells. J Neurochem 126:261-73.
13. Giedd JN. (2004) Structural magnetic resonance imaging of the adolescent brain. Ann N Y Acad Sci 1021:77-85.
14. Giedd JN. (2008) The teen brain: insights from neuroimaging. J Adolesc Health 42:335-43.
15. Girolamo F, Ferrara G, Strippoli M et al. (2011) Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis. Neurobiol Dis 43:678-89.
16. Grant BF, Dawson DA. (1997) Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. J Subst Abuse 9:103-10.
17. Guerri C, Pascual M. (2010) Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence. Alcohol 44:15-26.
18. Hawkins JD, Graham JW, Maguin E et al. (1997) Exploring the effects of age of alcohol use initiation and psychosocial risk factors on subsequent alcohol misuse. J Stud Alcohol 58: 280-90.
19. Hibell B, Guttormsson U, Ahlström S et al. (2009) The 2007 ESPAD Report. The Swedish Council for Information on alcohol and Other Drugs. Stockholm, Sweden.
20. Jacobus J, Tapert SF. (2013) Neurotoxic effects of alcohol in adolescence. Annu Rev Clin Psychol 9:703-21.
21. Johnson L, O'Malley P, Bachman J et al. (2009) Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings, 2008. NIH Publication No. 09-7401. Bethesda, MD: National Institute on Drug Abuse.
22. Kang SH, Fukaya M, Yang JK et al. (2010) NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration. Neuron 68: 668-81.
23. Labouvie E, Bates ME, Pandina RJ. (1997) Age of first use: its reliability and predictive utility. J Stud Alcohol 58:638-43.
24. Lewohl JM, Wixey J, Harper CG et al. (2005) Expression of MBP, PLP, MAG, CNP, and GFAP in the human alcoholic brain. Alcohol Clin Exp Res 29:1698-705.
25. Medina KL, McQueeny T, Nagel BJ et al. (2008) Prefrontal cortex volumes in adolescents with alcohol use disorders: unique gender effects. Alcohol Clin Exp Res 32:386-94.
26. Nguyen T, Mehta NR, Conant K et al. (2009) Axonal protective effects of the myelin-associated glycoprotein. J Neurosci 29:630-7.
27. Pascual M, Blanco AM, Cauli O et al. (2007) Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats. Eur J Neurosci 25:541-50.
28. Pascual M, Boix J, Felipo V et al. (2009) Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat. J Neurochem 108:920-31.
29. Pascual M, Do Couto BR, Alfonso-Loeches S et al. (2012) Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning. Neuropharmacology 62:2309-19.
30. Paus T, Zijdenbos A,Worsley K et al. (1999) Structural maturation of neural pathways in children and adolescents: in vivo study. Science 283:1908-11.
31. Paus T, Keshavan M, Giedd JN. (2008) Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 9:947-57.
32. Pfefferbaum A, Rosenbloom M, Rohlfing T et al. (2009) Degradation of association and projection white matter systems in alcoholism detected with quantitative fiber tracking. Biol Psychiatry 65:680-90.
33. Philpot R, Kirstein C. (2004) Developmental differences in the accumbal dopaminergic response to repeated ethanol exposure. Ann N Y Acad Sci 1021:422-6.
34. Ribeiro Do Couto B, Rodriguez-Arias M, Fuentes S et al. (2011) Adolescent pre-exposure to ethanol or MDMA prolongs the conditioned rewarding effects of MDMA. Physiol Behav 103: 585-93.
35. Ribeiro Do Couto B, Daza-Losada M, Rodriguez-Arias M et al. (2012) Adolescent pre-exposure to ethanol and 3,4-methylenedio xymethylamphetamine (MDMA) increases conditioned rewarding effects of MDMA and drug-induced reinstatement. Addict Biol 17:588-600.
36. Schweinsburg AD, McQueeny T, Nagel BJ et al. (2010) A preliminary study of functional magnetic resonance imaging response during verbal encoding among adolescent binge drinkers. Alcohol 44:111-7.
37. Sircar R, Sircar D. (2005) Adolescent rats exposed to repeated ethanol treatment show lingering behavioral impairments. Alcohol Clin Exp Res 29:1402-10.
38. Tapert SF, Brown SA, Myers MG et al. (1999) The role of neurocognitive abilities in coping with adolescent relapse to alcohol and drug use. J Stud Alcohol 60:500-8.
39. Tapert SF, Ozyurt SS, Myers MG et al. (2004) Neurocognitive ability in adults coping with alcohol and drug relapse temptations. Am J Drug Alcohol Abuse 30:445-60.
40. Vetreno RP, Crews FT. (2012) Adolescent binge drinking increases expression of the danger signal receptor agonist HMGB1 and Toll-like receptors in the adult prefrontal cortex. Neuroscience 226:475-88.
41. Vetreno RP, Qin L, Crews FT. (2013) Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking. Neurobiol Dis 59:52-62.
42. Vidal-Infer A, Aguilar MA, Minarro J et al. (2012) Effect of intermittent exposure to ethanol and MDMA during adolescence on learning and memory in adult mice. Behav Brain Funct 8:32.
43. Welch KA, Carson A, Lawrie SM. (2013) Brain structure in adolescents and young adults with alcohol problems: systematic review of imaging studies. Alcohol Alcohol 48:433-44.
44. Witt ED. (2007) Puberty, hormones, and sex differences in alcohol abuse and dependence. Neurotoxicol Teratol 29:81-95.
45. Zeigler DW, Wang CC, Yoast RA et al. (2005) The neurocognitive effects of alcohol on adolescents and college students. Prev Med 40:23-32.