Solution structure of a sponge-derived cystine knot peptide and its notable stability

Journal of Natural Products

Volumn 77, Issue 2, 2014, Pages 304-310

  Li, Huayue ^a   Su, Mingzhi ^a   Hamann, Mark T ^b   Bowling, John J ^b,d   Kim, Hyung Sik ^c   Jung, Jee H ^a  

^a Pusan National University   (South Korea)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c Sungkyunkwan University   (South Korea)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASTEROPSIN E; CHYMOTRYPSIN; ELASTASE; KNOTTIN; PEPSIN A; PROLINE; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ASTEROPUS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME STABILITY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR OVERHAUSER EFFECT; PLASMA; PROTEIN MODIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE ALIGNMENT; SPONGE (PORIFERA); TANDEM MASS SPECTROMETRY; TOXICITY TESTING;

AMINO ACID SEQUENCE; ANIMALS; CHYMOTRYPSIN; CRYSTALLOGRAPHY, X-RAY; CYSTINE; HUMANS; MARINE BIOLOGY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PANCREATIC ELASTASE; PEPSIN A; PEPTIDES; PORIFERA; PROTEIN CONFORMATION; STEREOISOMERISM; TRYPSIN;

EID: 84896834876     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400899a     Document Type: Article

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