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Volumn 59, Issue 2, 2014, Pages 110-115

Confounding by linkage disequilibrium

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SEX HORMONE BINDING GLOBULIN;

EID: 84896834277     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2013.130     Document Type: Letter
Times cited : (16)

References (42)
  • 1
    • 78649794378 scopus 로고    scopus 로고
    • The meaning of interaction
    • Wang, X., Elston, R. C. & Zhu, X. The meaning of interaction. Hum. Hered. 70, 269-277 (2010).
    • (2010) Hum. Hered. , vol.70 , pp. 269-277
    • Wang, X.1    Elston, R.C.2    Zhu, X.3
  • 2
    • 0023146886 scopus 로고
    • Definition and properties of disequilibrium statistics for associations between nuclear and cytoplasmic genotypes
    • Asmussen, M. A., Arnold, J. & Avise, J. C. Definition and properties of disequilibrium statistics for associations between nuclear and cytoplasmic genotypes. Genetics 115, 755-768 (1987).
    • (1987) Genetics , vol.115 , pp. 755-768
    • Asmussen, M.A.1    Arnold, J.2    Avise, J.C.3
  • 4
    • 0018218088 scopus 로고
    • An improper use of statistical significance testing in studying covariables
    • Dales, L. G. & Ury, H. K. An improper use of statistical significance testing in studying covariables. Int. J. Epidemiol. 7, 373-375 (1978).
    • (1978) Int. J. Epidemiol. , vol.7 , pp. 373-375
    • Dales, L.G.1    Ury, H.K.2
  • 5
    • 0030203887 scopus 로고    scopus 로고
    • Growth factors and cytokines in uterine leiomyomas
    • Andersen, J. Growth factors and cytokines in uterine leiomyomas. Semin. Reprod. Endocrinol. 14, 269-282 (1996).
    • (1996) Semin. Reprod. Endocrinol. , vol.14 , pp. 269-282
    • Andersen, J.1
  • 6
    • 0033669985 scopus 로고    scopus 로고
    • Epidemiologic contributions to understanding the etiology of uterine leiomyomata
    • Schwartz, S. M., Marshall, L. M. & Baird, D. D. Epidemiologic contributions to understanding the etiology of uterine leiomyomata. Environ. Health Perspect. 108(Suppl 5), 821-827 (2000).
    • (2000) Environ. Health Perspect. , vol.108 , Issue.SUPPL. 5 , pp. 821-827
    • Schwartz, S.M.1    Marshall, L.M.2    Baird, D.D.3
  • 9
    • 84875033916 scopus 로고    scopus 로고
    • Multiple hits for the association of uterine fibroids on human chromosome 1q43
    • Aissani, B., Wiener, H. & Zhang, K. Multiple hits for the association of uterine fibroids on human chromosome 1q43. PLoS One 8, e58399 (2013).
    • (2013) PLoS One , vol.8
    • Aissani, B.1    Wiener, H.2    Zhang, K.3
  • 10
    • 0035007528 scopus 로고    scopus 로고
    • Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43
    • Alam, N. A., Bevan, S., Churchman, M., Barclay, E., Barker, K., Jaeger, E. E. et al. Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. Am. J. Hum. Genet. 68, 1264-1269 (2001).
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 1264-1269
    • Alam, N.A.1    Bevan, S.2    Churchman, M.3    Barclay, E.4    Barker, K.5    Jaeger, E.E.6
  • 11
    • 18544365990 scopus 로고    scopus 로고
    • Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
    • Tomlinson, I. P., Alam, N. A., Rowan, A. J., Barclay, E., Jaeger, E. E., Kelsell, D. et al. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat. Genet. (2002)30, 406-410.
    • (2002) Nat. Genet. , vol.30 , pp. 406-410
    • Tomlinson, I.P.1    Alam, N.A.2    Rowan, A.J.3    Barclay, E.4    Jaeger, E.E.5    Kelsell, D.6
  • 12
    • 1542469716 scopus 로고    scopus 로고
    • Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors
    • Lehtonen, R., Kiuru, M., Vanharanta, S., Sjöberg, J., Aaltonen, L. M., Aittomäki, K. et al. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. Am. J. Pathol. 164, 17-22 (2004).
    • (2004) Am. J. Pathol. , vol.164 , pp. 17-22
    • Lehtonen, R.1    Kiuru, M.2    Vanharanta, S.3    Sjöberg, J.4    Aaltonen, L.M.5    Aittomäki, K.6
  • 13
    • 33846833908 scopus 로고    scopus 로고
    • A quantitative trait locus for body fat on chromosome 1q43 in French Canadians: Linkage and association studies
    • Aissani, B., Perusse, L., Lapointe, G., Chagnon, Y. C., Bouchard, L., Walts, B. et al. A quantitative trait locus for body fat on chromosome 1q43 in French Canadians: linkage and association studies. Obesity 14, 1605-1615 (2006).
    • (2006) Obesity , vol.14 , pp. 1605-1615
    • Aissani, B.1    Perusse, L.2    Lapointe, G.3    Chagnon, Y.C.4    Bouchard, L.5    Walts, B.6
  • 14
  • 15
    • 1542723754 scopus 로고    scopus 로고
    • Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Quebec Family Study
    • Bosse, Y., Chagnon, Y. C., Despres, J. P., Rice, T., Rao, D. C., Bouchard, C. et al. Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Quebec Family Study. J. Lipid Res. 45, 419-426 (2004).
    • (2004) J. Lipid Res. , vol.45 , pp. 419-426
    • Bosse, Y.1    Chagnon, Y.C.2    Despres, J.P.3    Rice, T.4    Rao, D.C.5    Bouchard, C.6
  • 16
    • 78951494711 scopus 로고    scopus 로고
    • Genome-wide linkage and peak-wide association study of obesityrelated quantitative traits in Caribbean Hispanics
    • Dong, C., Beecham, A., Slifer, S., Wang, L., McClendon, M. S., Blanton, S. H. et al. Genome-wide linkage and peak-wide association study of obesityrelated quantitative traits in Caribbean Hispanics. Hum. Genet. 129, 209-219 (2011).
    • (2011) Hum. Genet. , vol.129 , pp. 209-219
    • Dong, C.1    Beecham, A.2    Slifer, S.3    Wang, L.4    McClendon, M.S.5    Blanton, S.H.6
  • 17
    • 4644342943 scopus 로고    scopus 로고
    • Involvement of fumarate hydratase in nonsyndromic uterine leiomyomas: Genetic linkage analysis and FISH studies
    • Gross, K. L., Panhuysen, C. I., Kleinman, M. S., Goldhammer, H., Jones, E. S., Nassery, N. et al. Involvement of fumarate hydratase in nonsyndromic uterine leiomyomas: genetic linkage analysis and FISH studies. Genes Chromosomes Cancer 41, 183-190 (2004).
    • (2004) Genes Chromosomes Cancer , vol.41 , pp. 183-190
    • Gross, K.L.1    Panhuysen, C.I.2    Kleinman, M.S.3    Goldhammer, H.4    Jones, E.S.5    Nassery, N.6
  • 18
    • 84862777492 scopus 로고    scopus 로고
    • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
    • Stolk, L., Perry, J. R., Chasman, D. I., He, C., Mangino, M., Sulem, P. et al. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat. Genet. 44, 260-268 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 260-268
    • Stolk, L.1    Perry, J.R.2    Chasman, D.I.3    He, C.4    Mangino, M.5    Sulem, P.6
  • 19
    • 8944259906 scopus 로고    scopus 로고
    • Relation of energy, fat, and fiber intakes to plasma concentrations of estrogens and androgens in premenopausal women
    • Dorgan, J. F., Reichman, M. E., Judd, J. T., Brown, C., Longcope, C., Schatzkin, A. et al. Relation of energy, fat, and fiber intakes to plasma concentrations of estrogens and androgens in premenopausal women. Am. J. Clin. Nutr. 64, 25-31 (1996).
    • (1996) Am. J. Clin. Nutr. , vol.64 , pp. 25-31
    • Dorgan, J.F.1    Reichman, M.E.2    Judd, J.T.3    Brown, C.4    Longcope, C.5    Schatzkin, A.6
  • 20
    • 0036345144 scopus 로고    scopus 로고
    • A genome-wide linkage scan for steroids and SHBG levels in black and white families: The HERITAGE Family Study
    • Ukkola, O., Rankinen, T., Gagnon, J., Leon, A. S., Skinner, J. S., Wilmore, J. H. et al. A genome-wide linkage scan for steroids and SHBG levels in black and white families: the HERITAGE Family Study. J. Clin. Endocrinol. Metab. 87, 3708-3720 (2002).
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 3708-3720
    • Ukkola, O.1    Rankinen, T.2    Gagnon, J.3    Leon, A.S.4    Skinner, J.S.5    Wilmore, J.H.6
  • 21
    • 1842427830 scopus 로고    scopus 로고
    • The evolutionary dynamics of eukaryotic gene order
    • Hurst, L. D., Pal, C. & Lercher, M. J. The evolutionary dynamics of eukaryotic gene order. Nat. Rev. Genet. 5, 299-310 (2004).
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 299-310
    • Hurst, L.D.1    Pal, C.2    Lercher, M.J.3
  • 22
    • 70349566593 scopus 로고
    • Diabetes mellitus: A 'thrifty' genotype rendered detrimental by 'progress'?
    • Neel, J. V. Diabetes mellitus: a 'thrifty' genotype rendered detrimental by 'progress'? Am. J. Hum. Genet. 14, 353-362 (1962).
    • (1962) Am. J. Hum. Genet. , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 23
    • 0037266513 scopus 로고    scopus 로고
    • Energy metabolism and the evolution of reproductive suppression in the human female
    • Jasienska, G. Energy metabolism and the evolution of reproductive suppression in the human female. Acta Biotheor. 51, 1-18 (2003).
    • (2003) Acta Biotheor. , vol.51 , pp. 1-18
    • Jasienska, G.1
  • 24
    • 33749122708 scopus 로고    scopus 로고
    • Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants
    • Derti, A., Roth, F. P., Church, G. M. & Wu, C. T. Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants. Nat. Genet. 38, 1216-1220 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 1216-1220
    • Derti, A.1    Roth, F.P.2    Church, G.M.3    Wu, C.T.4
  • 26
    • 84866085726 scopus 로고    scopus 로고
    • Ultraconserved elements in the human genome: Association and transmission analyses of highly constrained singlenucleotide polymorphisms
    • Chiang, C. W., Liu, C. T., Lettre, G., Lange, L. A., Jorgensen, N. W., Keating, B. J. et al. Ultraconserved elements in the human genome: association and transmission analyses of highly constrained singlenucleotide polymorphisms. Genetics 192, 253-266 (2012).
    • (2012) Genetics , vol.192 , pp. 253-266
    • Chiang, C.W.1    Liu, C.T.2    Lettre, G.3    Lange, L.A.4    Jorgensen, N.W.5    Keating, B.J.6
  • 27
    • 78651256136 scopus 로고    scopus 로고
    • Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3
    • Chen, Z. J., Zhao, H., He, L., Shi, Y., Qin, Y., Shi, Y. et al. Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat. Genet. 43, 55-59 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 55-59
    • Chen, Z.J.1    Zhao, H.2    He, L.3    Shi, Y.4    Qin, Y.5    Shi, Y.6
  • 28
    • 84947899470 scopus 로고    scopus 로고
    • Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
    • Elks, C. E., Perry, J. R., Sulem, P., Chasman, D. I., Franceschini, N., He, C. et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat. Genet. 42, 1077-1085 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 1077-1085
    • Elks, C.E.1    Perry, J.R.2    Sulem, P.3    Chasman, D.I.4    Franceschini, N.5    He, C.6
  • 29
    • 84881168299 scopus 로고    scopus 로고
    • Association of adiposity genetic variants with menarche timing in 92,105 women of European descent
    • Fernandez-Rhodes, L., Demerath, E. W., Cousminer, D. L., Tao, R., Dreyfus, J. G., Esko, T. et al. Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am. J. Epidemiol. 178, 451-460 (2013).
    • (2013) Am. J. Epidemiol. , vol.178 , pp. 451-460
    • Fernandez-Rhodes, L.1    Demerath, E.W.2    Cousminer, D.L.3    Tao, R.4    Dreyfus, J.G.5    Esko, T.6
  • 31
    • 79952356805 scopus 로고    scopus 로고
    • Piecing together the FTO jigsaw
    • Frayling, T. M. & Ong, K. Piecing together the FTO jigsaw. Genome Biol. 12, 104 (2011).
    • (2011) Genome Biol. , vol.12 , pp. 104
    • Frayling, T.M.1    Ong, K.2
  • 32
    • 78049249912 scopus 로고    scopus 로고
    • Genetic susceptibility to obesity and related traits in childhood and adolescence: Influence of loci identified by genome-wide association studies
    • den Hoed, M., Ekelund, U., Brage, S., Grontved, A., Zhao, J. H., Sharp, S. J. et al. Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies. Diabetes 59, 2980-2988 (2010).
    • (2010) Diabetes , vol.59 , pp. 2980-2988
    • Den Hoed, M.1    Ekelund, U.2    Brage, S.3    Grontved, A.4    Zhao, J.H.5    Sharp, S.J.6
  • 33
    • 72449169954 scopus 로고    scopus 로고
    • The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI
    • Zhao, J., Bradfield, J. P., Li, M., Wang, K., Zhang, H., Kim, C. E. et al. The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI. Obesity 17, 2254-2257 (2009).
    • (2009) Obesity , vol.17 , pp. 2254-2257
    • Zhao, J.1    Bradfield, J.P.2    Li, M.3    Wang, K.4    Zhang, H.5    Kim, C.E.6
  • 34
    • 34548719076 scopus 로고    scopus 로고
    • Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes
    • Goring, H. H., Curran, J. E., Johnson, M. P., Dyer, T. D., Charlesworth, J., Cole, S. A. et al. Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat. Genet. 39, 1208-1216 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 1208-1216
    • Goring, H.H.1    Curran, J.E.2    Johnson, M.P.3    Dyer, T.D.4    Charlesworth, J.5    Cole, S.A.6
  • 35
    • 77952822074 scopus 로고    scopus 로고
    • PheWAS: Demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations
    • Denny, J. C., Ritchie, M. D., Basford, M. A., Pulley, J. M., Bastarache, L., Brown-Gentry, K. et al. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics 26, 1205-1210 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 1205-1210
    • Denny, J.C.1    Ritchie, M.D.2    Basford, M.A.3    Pulley, J.M.4    Bastarache, L.5    Brown-Gentry, K.6
  • 36
    • 80053206058 scopus 로고    scopus 로고
    • The Next PAGE in understanding complex traits: Design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study
    • Matise, T. C., Ambite, J. L., Buyske, S., Carlson, C. S., Cole, S. A., Crawford, D. C. et al. The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. Am. J. Epidemiol. 174, 849-859 (2011).
    • (2011) Am. J. Epidemiol. , vol.174 , pp. 849-859
    • Matise, T.C.1    Ambite, J.L.2    Buyske, S.3    Carlson, C.S.4    Cole, S.A.5    Crawford, D.C.6
  • 37
    • 78951491095 scopus 로고    scopus 로고
    • One hundred years of pleiotropy: A retrospective
    • Stearns, F. W. One hundred years of pleiotropy: a retrospective. Genetics 186, 767-773 (2010).
    • (2010) Genetics , vol.186 , pp. 767-773
    • Stearns, F.W.1
  • 38
    • 79951799418 scopus 로고    scopus 로고
    • The pleiotropic structure of the genotype-phenotype map: The evolvability of complex organisms
    • Wagner, G. P. & Zhang, J. The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat. Rev. Genet. 12, 204-213 (2011).
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 204-213
    • Wagner, G.P.1    Zhang, J.2
  • 39
    • 33747817940 scopus 로고    scopus 로고
    • Toward a molecular understanding of pleiotropy
    • He, X. & Zhang, J. Toward a molecular understanding of pleiotropy. Genetics 173, 1885-1891 (2006).
    • (2006) Genetics , vol.173 , pp. 1885-1891
    • He, X.1    Zhang, J.2
  • 40
    • 77950553262 scopus 로고    scopus 로고
    • Fumarase: A mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response
    • Yogev, O., Yogev, O., Singer, E., Shaulian, E., Golberg, M., Fox, T. D. et al. Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response. PLoS Biol. 8, e1000328 (2010).
    • (2010) PLoS Biol. , vol.8
    • Yogev, O.1    Yogev, O.2    Singer, E.3    Shaulian, E.4    Golberg, M.5    Fox, T.D.6
  • 41
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace, D. C. Mitochondrial diseases in man and mouse. Science 283, 1482-1488 (1999).
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1


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