-
1
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
-
1:CAS:528:DC%2BD3MXksVOrsL8%3D 11381127 10.1073/pnas.121119298
-
Alonso A, Zaidi T, Novak M, Grundke-Iqbal I, Iqbal K (2001) Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proc Natl Acad Sci USA 98(12):6923-6928
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.12
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
2
-
-
80052259754
-
Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I(2)(PP2A)/SET
-
1:CAS:528:DC%2BC3MXhtV2it7zL 3181127 21806989 10.1016/j.febslet.2011.07. 020
-
Arnaud L, Chen S, Liu F, Li B, Khatoon S, Grundke-Iqbal I, Iqbal K (2011) Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I(2)(PP2A)/SET. FEBS Lett 585(17):2653-2659
-
(2011)
FEBS Lett
, vol.585
, Issue.17
, pp. 2653-2659
-
-
Arnaud, L.1
Chen, S.2
Liu, F.3
Li, B.4
Khatoon, S.5
Grundke-Iqbal, I.6
Iqbal, K.7
-
3
-
-
84879047960
-
Activation of asparaginyl endopeptidase leads to tau hyperphosphorylation in Alzheimer's disease
-
10.1074/jbc.M112.446070 1:CAS:528:DC%2BC3sXpsFagtLw%3D 23640887 10.1074/jbc.M112.446070
-
Basurto-Islas G, Grundke-Iqbal I, Tung YC, Liu F, Iqbal K (2013) Activation of asparaginyl endopeptidase leads to tau hyperphosphorylation in Alzheimer's disease. J Biol Chem 288:17495-17507. doi: 10.1074/jbc.M112.446070
-
(2013)
J Biol Chem
, vol.288
, pp. 17495-17507
-
-
Basurto-Islas, G.1
Grundke-Iqbal, I.2
Tung, Y.C.3
Liu, F.4
Iqbal, K.5
-
4
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
10.1016/j.neuron.2011.09.011 1:CAS:528:DC%2BC3MXhtlKrtL%2FP 3202986 21944778 10.1016/j.neuron.2011.09.011
-
DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, Rutherford NJ, Nicholson AM, Finch NA, Flynn H, Adamson J, Kouri N, Wojtas A, Sengdy P, Hsiung GY, Karydas A, Seeley WW, Josephs KA, Coppola G, Geschwind DH, Wszolek ZK, Feldman H, Knopman DS, Petersen RC, Miller BL, Dickson DW, Boylan KB, Graff-Radford NR, Rademakers R (2011) Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 72(2):245-256. doi: 10.1016/j.neuron.2011.09.011
-
(2011)
Neuron
, vol.72
, Issue.2
, pp. 245-256
-
-
Dejesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
Rutherford, N.J.6
Nicholson, A.M.7
Finch, N.A.8
Flynn, H.9
Adamson, J.10
Kouri, N.11
Wojtas, A.12
Sengdy, P.13
Hsiung, G.Y.14
Karydas, A.15
Seeley, W.W.16
Josephs, K.A.17
Coppola, G.18
Geschwind, D.H.19
Wszolek, Z.K.20
Feldman, H.21
Knopman, D.S.22
Petersen, R.C.23
Miller, B.L.24
Dickson, D.W.25
Boylan, K.B.26
Graff-Radford, N.R.27
Rademakers, R.28
more..
-
5
-
-
80052580969
-
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
-
10.1038/nature10353 1:CAS:528:DC%2BC3MXhtFOlsLnM 3169705 21857683 10.1038/nature10353
-
Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, Yang Y, Fecto F, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen GH, Donkervoort S, Bigio EH, Brooks BR, Ajroud K, Sufit RL, Haines JL, Mugnaini E, Pericak-Vance MA, Siddique T (2011) Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature 477(7363):211-215. doi: 10.1038/nature10353
-
(2011)
Nature
, vol.477
, Issue.7363
, pp. 211-215
-
-
Deng, H.X.1
Chen, W.2
Hong, S.T.3
Boycott, K.M.4
Gorrie, G.H.5
Siddique, N.6
Yang, Y.7
Fecto, F.8
Shi, Y.9
Zhai, H.10
Jiang, H.11
Hirano, M.12
Rampersaud, E.13
Jansen, G.H.14
Donkervoort, S.15
Bigio, E.H.16
Brooks, B.R.17
Ajroud, K.18
Sufit, R.L.19
Haines, J.L.20
Mugnaini, E.21
Pericak-Vance, M.A.22
Siddique, T.23
more..
-
6
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu. Zn superoxide dismutase
-
1:CAS:528:DyaK3sXms1Oqtb4%3D 8351519 10.1126/science.8351519
-
Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, Getzoff ED, Hu P, Herzfeldt B, Roos RP et al (1993) Amyotrophic lateral sclerosis and structural defects in Cu. Zn superoxide dismutase. Science 261(5124):1047-1051
-
(1993)
Science
, vol.261
, Issue.5124
, pp. 1047-1051
-
-
Deng, H.X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.Y.6
Getzoff, E.D.7
Hu, P.8
Herzfeldt, B.9
Roos, R.P.10
-
7
-
-
0037423932
-
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
-
1:CAS:528:DC%2BD3sXitFykurc%3D 12628186 10.1016/S0092-8674(03)00150-8
-
Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J (2003) Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell 112(5):659-672
-
(2003)
Cell
, vol.112
, Issue.5
, pp. 659-672
-
-
Fan, Z.1
Beresford, P.J.2
Oh, D.Y.3
Zhang, D.4
Lieberman, J.5
-
8
-
-
0026076318
-
Pacific paradigms of environmentally-induced neurological disorders: Clinical, epidemiological and molecular perspectives
-
1:STN:280:DyaK38%2FotVWrsg%3D%3D 1745428
-
Garruto RM (1991) Pacific paradigms of environmentally-induced neurological disorders: clinical, epidemiological and molecular perspectives. Neurotoxicology 12(3):347-377
-
(1991)
Neurotoxicology
, vol.12
, Issue.3
, pp. 347-377
-
-
Garruto, R.M.1
-
9
-
-
0034088846
-
Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease
-
1:CAS:528:DC%2BD3cXhsFKktr4%3D 10681533 10.1074/jbc.275.8.5535
-
Gong CX, Lidsky T, Wegiel J, Zuck L, Grundke-Iqbal I, Iqbal K (2000) Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease. J Biol Chem 275(8):5535-5544
-
(2000)
J Biol Chem
, vol.275
, Issue.8
, pp. 5535-5544
-
-
Gong, C.X.1
Lidsky, T.2
Wegiel, J.3
Zuck, L.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
10
-
-
0029113874
-
Phosphatase activity toward abnormally phosphorylated tau: Decrease in Alzheimer disease brain
-
1:CAS:528:DyaK2MXntFGgsbg%3D 7616230 10.1046/j.1471-4159.1995.65020732.x
-
Gong CX, Shaikh S, Wang JZ, Zaidi T, Grundke-Iqbal I, Iqbal K (1995) Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain. J Neurochem 65(2):732-738
-
(1995)
J Neurochem
, vol.65
, Issue.2
, pp. 732-738
-
-
Gong, C.X.1
Shaikh, S.2
Wang, J.Z.3
Zaidi, T.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
11
-
-
0027214404
-
Phosphoprotein phosphatase activities in Alzheimer disease brain
-
1:CAS:528:DyaK2cXivVKisQ%3D%3D 8395566 10.1111/j.1471-4159.1993.tb03603.x
-
Gong CX, Singh TJ, Grundke-Iqbal I, Iqbal K (1993) Phosphoprotein phosphatase activities in Alzheimer disease brain. J Neurochem 61(3):921-927
-
(1993)
J Neurochem
, vol.61
, Issue.3
, pp. 921-927
-
-
Gong, C.X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
12
-
-
0345700240
-
Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices
-
1:CAS:528:DC%2BD3sXisV2lsr8%3D 12668248 10.1016/S0304-3940(03)00096-X
-
Gong CX, Wang JZ, Iqbal K, Grundke-Iqbal I (2003) Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices. Neurosci Lett 340(2):107-110
-
(2003)
Neurosci Lett
, vol.340
, Issue.2
, pp. 107-110
-
-
Gong, C.X.1
Wang, J.Z.2
Iqbal, K.3
Grundke-Iqbal, I.4
-
13
-
-
0344665680
-
Transgenic and knockout models of PP2A
-
14674263
-
Gotz J, Schild A (2003) Transgenic and knockout models of PP2A. Methods Enzymol 366:390-403
-
(2003)
Methods Enzymol
, vol.366
, pp. 390-403
-
-
Gotz, J.1
Schild, A.2
-
14
-
-
0023009658
-
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments
-
1:CAS:528:DyaL28XitVCqsb0%3D 3084478
-
Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi MS, Wisniewski HM (1986) Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J Biol Chem 261(13):6084-6089
-
(1986)
J Biol Chem
, vol.261
, Issue.13
, pp. 6084-6089
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Quinlan, M.3
Tung, Y.C.4
Zaidi, M.S.5
Wisniewski, H.M.6
-
15
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
1:CAS:528:DyaL28XksFyqtrg%3D 3088567 10.1073/pnas.83.13.4913
-
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI (1986) Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci USA 83(13):4913-4917
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, Issue.13
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
16
-
-
73049132762
-
Parkinsonism-dementia complex, an endemic disease on the island of Guam. I. Clinical features
-
1:STN:280:DyaF38%2FkvV2qtg%3D%3D 13907609 10.1093/brain/84.4.642
-
Hirano A, Kurland LT, Krooth RS, Lessell S (1961) Parkinsonism-dementia complex, an endemic disease on the island of Guam. I. Clinical features. Brain 84:642-661
-
(1961)
Brain
, vol.84
, pp. 642-661
-
-
Hirano, A.1
Kurland, L.T.2
Krooth, R.S.3
Lessell, S.4
-
17
-
-
0000035923
-
Parkinsonism-dementia complex, an endemic disease on the island of Guam. II. Pathological features
-
1:STN:280:DyaF38%2FkvV2qtw%3D%3D 13907610 10.1093/brain/84.4.662
-
Hirano A, Malamud N, Kurland LT (1961) Parkinsonism-dementia complex, an endemic disease on the island of Guam. II. Pathological features. Brain 84:662-679
-
(1961)
Brain
, vol.84
, pp. 662-679
-
-
Hirano, A.1
Malamud, N.2
Kurland, L.T.3
-
18
-
-
19944375450
-
Tau pathology in Alzheimer disease and other tauopathies
-
1:CAS:528:DC%2BD2cXhtFahsrjO 15615638 10.1016/j.bbadis.2004.09.008
-
Iqbal K, Alonso A, Chen S, Chohan MO, El-Akkad E, Gong CX, Khatoon S, Li B, Liu F, Rahman A, Tanimukai H, Grundke-Iqbal I (2005) Tau pathology in Alzheimer disease and other tauopathies. Biochim Biophys Acta 1739(2-3):198-210
-
(2005)
Biochim Biophys Acta
, vol.1739
, Issue.2-3
, pp. 198-210
-
-
Iqbal, K.1
Alonso, A.2
Chen, S.3
Chohan, M.O.4
El-Akkad, E.5
Gong, C.X.6
Khatoon, S.7
Li, B.8
Liu, F.9
Rahman, A.10
Tanimukai, H.11
Grundke-Iqbal, I.12
-
19
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
1:CAS:528:DC%2BD1MXit1eltbw%3D 19251627 10.1126/science.1166066
-
Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Valdmanis P, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, Yoshinaga Y, Haines JL, Pericak-Vance MA, Yan J, Ticozzi N, Siddique T, McKenna-Yasek D, Sapp PC, Horvitz HR, Landers JE, Brown RH Jr (2009) Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 323(5918):1205-1208
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1205-1208
-
-
Kwiatkowski, Jr.T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
Davis, A.7
Gilchrist, J.8
Kasarskis, E.J.9
Munsat, T.10
Valdmanis, P.11
Rouleau, G.A.12
Hosler, B.A.13
Cortelli, P.14
De Jong, P.J.15
Yoshinaga, Y.16
Haines, J.L.17
Pericak-Vance, M.A.18
Yan, J.19
Ticozzi, N.20
Siddique, T.21
McKenna-Yasek, D.22
Sapp, P.C.23
Horvitz, H.R.24
Landers, J.E.25
Brown, Jr.R.H.26
more..
-
20
-
-
0029889342
-
The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A
-
1:CAS:528:DyaK28XivV2jurc%3D 8626647 10.1074/jbc.271.19.11059
-
Li M, Makkinje A, Damuni Z (1996) The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A. J Biol Chem 271(19):11059-11062
-
(1996)
J Biol Chem
, vol.271
, Issue.19
, pp. 11059-11062
-
-
Li, M.1
Makkinje, A.2
Damuni, Z.3
-
21
-
-
27644478606
-
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
-
10.1111/j.1460-9568.2005.04391.x
-
Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2005) Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur J Neurosci 8:1942-1950
-
(2005)
Eur J Neurosci
, vol.8
, pp. 1942-1950
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Gong, C.X.4
-
22
-
-
40849111819
-
Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase
-
1:CAS:528:DC%2BD1cXksVGktr4%3D 2819101 18374643 10.1016/j.molcel.2008.02. 017
-
Liu Z, Jang SW, Liu X, Cheng D, Peng J, Yepes M, Li XJ, Matthews S, Watts C, Asano M, Hara-Nishimura I, Luo HR, Ye K (2008) Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Mol Cell 29(6):665-678
-
(2008)
Mol Cell
, vol.29
, Issue.6
, pp. 665-678
-
-
Liu, Z.1
Jang, S.W.2
Liu, X.3
Cheng, D.4
Peng, J.5
Yepes, M.6
Li, X.J.7
Matthews, S.8
Watts, C.9
Asano, M.10
Hara-Nishimura, I.11
Luo, H.R.12
Ye, K.13
-
23
-
-
56749098112
-
Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC)
-
1:CAS:528:DC%2BD1cXhtlyhsbbF 18843496 10.1007/s00401-008-0439-2
-
Miklossy J, Steele JC, Yu S, McCall S, Sandberg G, McGeer EG, McGeer PL (2008) Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC). Acta Neuropathol 116(6):625-637
-
(2008)
Acta Neuropathol
, vol.116
, Issue.6
, pp. 625-637
-
-
Miklossy, J.1
Steele, J.C.2
Yu, S.3
McCall, S.4
Sandberg, G.5
McGeer, E.G.6
McGeer, P.L.7
-
24
-
-
34249901269
-
Similar topographical distribution of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia complex in people living in the Kii peninsula of Japan suggests a single tauopathy
-
17277950 10.1007/s00401-007-0197-6
-
Mimuro M, Kokubo Y, Kuzuhara S (2007) Similar topographical distribution of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia complex in people living in the Kii peninsula of Japan suggests a single tauopathy. Acta Neuropathol 113(6):653-658
-
(2007)
Acta Neuropathol
, vol.113
, Issue.6
, pp. 653-658
-
-
Mimuro, M.1
Kokubo, Y.2
Kuzuhara, S.3
-
25
-
-
0028081824
-
Amyotrophic lateral sclerosis of Guam: The nature of the neuropathological findings
-
1:STN:280:DyaK2M7kvFKrtA%3D%3D 7847068 10.1007/BF00389491
-
Oyanagi K, Makifuchi T, Ohtoh T, Chen KM, van der Schaaf T, Gajdusek DC, Chase TN, Ikuta F (1994) Amyotrophic lateral sclerosis of Guam: the nature of the neuropathological findings. Acta Neuropathol 88(5):405-412
-
(1994)
Acta Neuropathol
, vol.88
, Issue.5
, pp. 405-412
-
-
Oyanagi, K.1
Makifuchi, T.2
Ohtoh, T.3
Chen, K.M.4
Van Der Schaaf, T.5
Gajdusek, D.C.6
Chase, T.N.7
Ikuta, F.8
-
26
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
doi: 10.1016/j.neuron.2011.09.010
-
Renton AE, Majounie E, Waite A, Simon-Sanchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, Kalimo H, Paetau A, Abramzon Y, Remes AM, Kaganovich A, Scholz SW, Duckworth J, Ding J, Harmer DW, Hernandez DG, Johnson JO, Mok K, Ryten M, Trabzuni D, Guerreiro RJ, Orrell RW, Neal J, Murray A, Pearson J, Jansen IE, Sondervan D, Seelaar H, Blake D, Young K, Halliwell N, Callister JB, Toulson G, Richardson A, Gerhard A, Snowden J, Mann D, Neary D, Nalls MA, Peuralinna T, Jansson L, Isoviita VM, Kaivorinne AL, Holtta-Vuori M, Ikonen E, Sulkava R, Benatar M, Wuu J, Chio A, Restagno G, Borghero G, Sabatelli M, Consortium I, Heckerman D, Rogaeva E, Zinman L, Rothstein JD, Sendtner M, Drepper C, Eichler EE, Alkan C, Abdullaev Z, Pack SD, Dutra A, Pak E, Hardy J, Singleton A, Williams NM, Heutink P, Pickering-Brown S, Morris HR, Tienari PJ, Traynor BJ (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 72(2):257-268. doi: 10.1016/j.neuron.2011.09.010
-
(2011)
Neuron
, vol.72
, Issue.2
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
Simon-Sanchez, J.4
Rollinson, S.5
Gibbs, J.R.6
Schymick, J.C.7
Laaksovirta, H.8
Van Swieten, J.C.9
Myllykangas, L.10
Kalimo, H.11
Paetau, A.12
Abramzon, Y.13
Remes, A.M.14
Kaganovich, A.15
Scholz, S.W.16
Duckworth, J.17
Ding, J.18
Harmer, D.W.19
Hernandez, D.G.20
Johnson, J.O.21
Mok, K.22
Ryten, M.23
Trabzuni, D.24
Guerreiro, R.J.25
Orrell, R.W.26
Neal, J.27
Murray, A.28
Pearson, J.29
Jansen, I.E.30
Sondervan, D.31
Seelaar, H.32
Blake, D.33
Young, K.34
Halliwell, N.35
Callister, J.B.36
Toulson, G.37
Richardson, A.38
Gerhard, A.39
Snowden, J.40
Mann, D.41
Neary, D.42
Ma, N.43
Peuralinna, T.44
Jansson, L.45
Isoviita, V.M.46
Kaivorinne, A.L.47
Holtta-Vuori, M.48
Ikonen, E.49
Sulkava, R.50
Benatar, M.51
Wuu, J.52
Chio, A.53
Restagno, G.54
Borghero, G.55
Sabatelli, M.56
Consortium, I.57
Heckerman, D.58
Rogaeva, E.59
Zinman, L.60
Rothstein, J.D.61
Sendtner, M.62
Drepper, C.63
Eichler, E.E.64
Alkan, C.65
Abdullaev, Z.66
Pack, S.D.67
Dutra, A.68
Pak, E.69
Hardy, J.70
Singleton, A.71
Williams, N.M.72
Heutink, P.73
Pickering-Brown, S.74
Morris, H.R.75
Tienari, P.J.76
Traynor, B.J.77
more..
-
27
-
-
0035846894
-
Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein
-
1:CAS:528:DC%2BD3MXis1Oqs70%3D 11163245 10.1016/S0092-8674(01)00196-9
-
Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D (2001) Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell 104(1):119-130
-
(2001)
Cell
, vol.104
, Issue.1
, pp. 119-130
-
-
Seo, S.B.1
McNamara, P.2
Heo, S.3
Turner, A.4
Lane, W.S.5
Chakravarti, D.6
-
28
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
1:CAS:528:DC%2BD1cXjsVamtbo%3D 18309045 10.1126/science.1154584
-
Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, Ackerley S, Durnall JC, Williams KL, Buratti E, Baralle F, de Belleroche J, Mitchell JD, Leigh PN, Al-Chalabi A, Miller CC, Nicholson G, Shaw CE (2008) TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 319(5870):1668-1672
-
(2008)
Science
, vol.319
, Issue.5870
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
De Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
29
-
-
0021854395
-
Aberrant neurofilament phosphorylation in Alzheimer disease
-
1:STN:280:DyaL2M3hs1KktA%3D%3D 3159022 10.1073/pnas.82.12.4274
-
Sternberger NH, Sternberger LA, Ulrich J (1985) Aberrant neurofilament phosphorylation in Alzheimer disease. Proc Natl Acad Sci USA 82(12):4274-4276
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, Issue.12
, pp. 4274-4276
-
-
Sternberger, N.H.1
Sternberger, L.A.2
Ulrich, J.3
-
30
-
-
3042711967
-
Inhibitors of protein phosphatase-2A: Topography and subcellular localization
-
1:CAS:528:DC%2BD2cXlsFOqsbg%3D 15249138 10.1016/j.molbrainres.2004.04.003
-
Tanimukai H, Grundke-Iqbal I, Iqbal K (2004) Inhibitors of protein phosphatase-2A: topography and subcellular localization. Brain Res Mol Brain Res 126(2):146-156
-
(2004)
Brain Res Mol Brain Res
, vol.126
, Issue.2
, pp. 146-156
-
-
Tanimukai, H.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
31
-
-
19544362550
-
Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease
-
1:CAS:528:DC%2BD2MXlsFynsrc%3D 15920161 10.1016/S0002-9440(10)62486-8
-
Tanimukai H, Grundke-Iqbal I, Iqbal K (2005) Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease. Am J Pathol 166(6):1761-1771
-
(2005)
Am J Pathol
, vol.166
, Issue.6
, pp. 1761-1771
-
-
Tanimukai, H.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
32
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
1:CAS:528:DC%2BD1MXit1eltbs%3D 19251628 10.1126/science.1165942
-
Vance C, Rogelj B, Hortobagyi T, De Vos KJ, Nishimura AL, Sreedharan J, Hu X, Smith B, Ruddy D, Wright P, Ganesalingam J, Williams KL, Tripathi V, Al-Saraj S, Al-Chalabi A, Leigh PN, Blair IP, Nicholson G, de Belleroche J, Gallo JM, Miller CC, Shaw CE (2009) Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 323(5918):1208-1211
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
Hu, X.7
Smith, B.8
Ruddy, D.9
Wright, P.10
Ganesalingam, J.11
Williams, K.L.12
Tripathi, V.13
Al-Saraj, S.14
Al-Chalabi, A.15
Leigh, P.N.16
Blair, I.P.17
Nicholson, G.18
De Belleroche, J.19
Gallo, J.M.20
Miller, C.C.21
Shaw, C.E.22
more..
-
33
-
-
79958815089
-
Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments
-
Veeranna, Yang DS, Lee JH, Vinod KY, Stavrides P, Amin ND, Pant HC, Nixon RA (2009) Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments. Neurobiol Aging
-
(2009)
Neurobiol Aging
-
-
Veeranna1
Yang, D.S.2
Lee, J.H.3
Vinod, K.Y.4
Stavrides, P.5
Amin, N.D.6
Pant, H.C.7
Nixon, R.A.8
-
34
-
-
78649859760
-
The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment
-
1:CAS:528:DC%2BC3cXhsVWqu7vF 20651003 10.1096/fj.10-158477
-
Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden RM, Radu A, Grundke-Iqbal I, Iqbal K (2010) The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. FASEB J 24(11):4420-4432
-
(2010)
FASEB J
, vol.24
, Issue.11
, pp. 4420-4432
-
-
Wang, X.1
Blanchard, J.2
Kohlbrenner, E.3
Clement, N.4
Linden, R.M.5
Radu, A.6
Grundke-Iqbal, I.7
Iqbal, K.8
-
35
-
-
33751243629
-
Neuronal intermediate filaments and ALS: A new look at an old question
-
10.1016/j.bbadis.2006.09.003 1:CAS:528:DC%2BD28Xht1CgsLnN 17045786 10.1016/j.bbadis.2006.09.003
-
Xiao S, McLean J, Robertson J (2006) Neuronal intermediate filaments and ALS: a new look at an old question. Biochim Biophys Acta 1762(11-12):1001-1012. doi: 10.1016/j.bbadis.2006.09.003
-
(2006)
Biochim Biophys Acta
, vol.1762
, Issue.11-12
, pp. 1001-1012
-
-
Xiao, S.1
McLean, J.2
Robertson, J.3
-
36
-
-
84875854908
-
Ser9 phosphorylation causes cytoplasmic detention of I2(PP2A)/SET in Alzheimer disease
-
10.1016/j.neurobiolaging.2012.12.025 1:CAS:528:DC%2BC3sXhvFSnsbg%3D 23374587 10.1016/j.neurobiolaging.2012.12.025
-
Yu G, Yan T, Feng Y, Liu X, Xia Y, Luo H, Wang JZ, Wang X (2013) Ser9 phosphorylation causes cytoplasmic detention of I2(PP2A)/SET in Alzheimer disease. Neurobiol Aging 34(7):1748-1758. doi: 10.1016/j.neurobiolaging.2012.12. 025
-
(2013)
Neurobiol Aging
, vol.34
, Issue.7
, pp. 1748-1758
-
-
Yu, G.1
Yan, T.2
Feng, Y.3
Liu, X.4
Xia, Y.5
Luo, H.6
Wang, J.Z.7
Wang, X.8
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