A preliminary study in Wistar rats with enniatin A contaminated feed

Toxicology Mechanisms and Methods

Volumn 24, Issue 3, 2014, Pages 179-190

  Manyes, Lara ^a   Escrivá, Laura ^a   Serrano, Ana Belén ^a   Rodríguez Carrasco, Yelko ^a   Tolosa, Josefa ^a   Meca, Giuseppe ^a   Font, Guillermina ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Enniatin A; Fusarium tricinctum; in vivo study; LC DAD; LC MS LIT

Indexed keywords

ENNIATIN; DEPSIPEPTIDE; ENNIATINS;

ABSORPTION; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CHEMICAL ANALYSIS; COLON; CONTROLLED STUDY; DUODENUM; FOOD CONTAMINATION; FUSARIUM TRICINCTUM; ILEUM; IN VIVO STUDY; JEJUNUM; LIQUID CHROMATOGRAPHY; LIVER; MASS SPECTROMETRY; MICROFLORA; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH; STOMACH CONTENT; ANALYSIS; ANIMAL; ANIMAL FOOD; FEMALE; FERMENTATION; INTESTINE; INTESTINE ABSORPTION; METABOLISM; TOXICITY; WISTAR RAT;

ANIMAL FEED; ANIMALS; CHROMATOGRAPHY, LIQUID; DEPSIPEPTIDES; FEMALE; FERMENTATION; FOOD CONTAMINATION; INTESTINAL ABSORPTION; INTESTINES; MASS SPECTROMETRY; RATS, WISTAR;

EID: 84896822545     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2013.876135     Document Type: Article

References (24)

1. Akbas Y, Pata YS, Unal M, et al. (2004). The effect of fusafungine on post-operative pain and wound healing after pediatric tonsillectomy. Int J Pediatr Otorhinolaryngol 68:1023-6.
2. Behm C, Degen GH, Follmann W. (2009). The Fusarium toxin enniatin B exerts no genotoxic activity, but pronounced cytotoxicity in vitro. Mol Nutr Food Res 53:423-30.
3. Bosch U, Mirocha CJ, Abbas HK, Dimenna M. (1989). Toxicity and toxin production by Fusarium isolates from New Zealand. Mycopathologia 108:73-9.
4. Chelkowski J, Ritieni A, Wisniewska H, et al. (2007). Occurrence of toxic hexadepsipeptides in preharvest maize ear rot infected by Fusarium poae in Poland. J Phytopathol 155:8-10.
5. Dornetshuber R, Heffeter P, Lemmens-Gruber R, et al. (2009). Oxidative stress and DNA interactions are not involved in enniatin-And beauvericin-mediated apoptosis induction. Mol Nutr Food Res 53: 1112-22.
6. Fornelli F, Minervini F, Logrieco A. (2004). Cytotoxicity of fungal metabolites to lepidopteran (Spodoptera frugiperda) cell line (SF 9). J Invertebr Pathol 85:74-9.
7. Hayes WA. (2007). Principles and techniques of toxicology. 5th ed., Vol. 39. San Diego (CA): CRC press, Taylor and Francis group, 1924-65.
8. Hyun U, Lee DH, Lee C, Shin CG. (2009). Apoptosis induced by enniatins H and MK1688 isolated from Fusarium oxysporum FB1501. Toxicon 53:723-8.
9. Ivanova L, Eystein Skjerve E, Eriksen GS, Uhlig S. (2006). Cytotoxicity of enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum. Toxicon 47:868-76.
10. Jestoi M. (2008). Emerging Fusarium-mycotoxins fusaproliferin, beauvericin, enniatins, and moniliformin. A review. Crit Rev Food Sci Nutr 48:21-49.
11. Kelly S, Grimm LH, Bendig C, et al. (2006). Effects of fluid dynamic induced shear stress on fungal growth and morphology. Process Biochem 41:2113-17.
12. Kerns E, Di L. (2008). Drug like properties: Concepts, structure design and methods, from the ADME to toxicity optimization. Philadelphia (PA): Elsevier Inc., 28-9.
13. Lee HS, Song HH, Jeong JH, et al. (2008). Cytotoxicities of enniatins H, I, and MK1688 from Fusarium oxysporum KFCC 11363P. Toxicon 51:1178-85.
14. McKee TC, Bokesch HR, McCormick JL, et al. (1997). Isolation and characterization of new anti-HIV and cytotoxic leads from plants, marine and microbial origins. J Nat Prod 60:431-8.
15. Meca G, Font G, Ruiz MJ. (2011). Comparative cytotoxicity study of enniatins A, A1, A2, B, B1, B4 and J3 on Caco-2 cells, Hep-G2 and HT-29. Toxicon 49:2464-9.
16. Meca G, Meneghelli G, Ritieni A, Mañes J. (2012). Influence of different soluble dietary fibers on the bioaccessibility of the minor Fusarium mycotoxin beauvericin. Food Chem Toxicol 50:1362-8.
17. Meca G, Ruiz MJ, Soriano JM, et al. (2010a). Isolation and purification of enniatins A, A1, B, B1, produced by Fusarium tricinctum in solid culture, and cytotoxicity effects on Caco-2 cells. Toxicon 56: 418-24.
18. Meca G, Zinedine A, Blesa J, et al. (2010b). Further data on the presence of Fusarium emerging mycotoxins enniatins, fusaproliferin and beauvericin in cereals available on the Spanish markets. Food Chem Toxicol 48:1412-16.
19. Serrano AB, Meca G, Font G, Ferrer E. (2012). Risk assessment associated to the intake of the emerging Fusarium mycotoxins BEA, ENs and FUS present in infant formula of Spanish origin. Food Control 28:178-83.
20. Supothina S, Isaka M, Kirtikara K, et al. (2004). Enniatin production by the entomopathogenic fungus Verticillium hemipterigenum BCC 1449. J Antibiot 57:732-8.
21. Tonshin AA, Teplova VV, Andersson MA, Salkinoja-Salonen MS. (2010). The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. Toxicology 276:49-57.
22. Vongvilai P, Isaka M, Kittakoop P, et al. (2004). Isolation and structure elucidation of enniatins L, M-1, M-2, and N: Novel hydroxy analogs. Helv Chem Acta 87:2066-73.
23. Watjen W, Debbab A, Hohlfeld A, et al. (2009). Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Mol Nutr Food Res 53: 431-40.
24. Zhukhlistova NE, Tishchenko GN, Tolstykh IV, Zenkova VA. (1999). X-ray crystal structure of the complex of enniatin B with KNCS. Crystallogr Rep 44:8-12.