-
2
-
-
85157266211
-
-
Clinical trials. Efficacy and safety of PT003, PT005, and PT001 in subjects with moderate to severe COPD (PINNACLE 1)
-
Clinical trials. Efficacy and safety of PT003, PT005, and PT001 in subjects with moderate to severe COPD (PINNACLE 1). www.clinicaltrials.gov/ct2/ show/NCT01854645
-
-
-
-
4
-
-
42049094490
-
Pharmaceutical particle engineering via spray drying
-
Vehring R. Pharmaceutical particle engineering via spray drying. Pharm. Res. 25, 999-1022 (2007).
-
(2007)
Pharm. Res.
, vol.25
, pp. 999-1022
-
-
Vehring, R.1
-
5
-
-
77954860783
-
The use of modeling in spray drying of emulsions and suspensions accelerates formulation and process development
-
Ivey J W, Vehring R. The use of modeling in spray drying of emulsions and suspensions accelerates formulation and process development. Computers Chem. Eng. 34, 1036-1040 (2010).
-
(2010)
Computers Chem. Eng.
, vol.34
, pp. 1036-1040
-
-
Ivey, J.W.1
Vehring, R.2
-
7
-
-
42049100251
-
Embedded crystals in low density particles: Formulation, manufacture, and properties
-
Weers JG, Tarara T, Malcolmson R, Leung D. Embedded crystals in low density particles: formulation, manufacture, and properties. Proc. Resp. Drug Del. 297-304 (2006).
-
(2006)
Proc. Resp. Drug Del.
, pp. 297-304
-
-
Weers, J.G.1
Tarara, T.2
Malcolmson, R.3
Leung, D.4
-
8
-
-
0006189298
-
Dispersible powders for inhalation applications
-
Weers JG. Dispersible powders for inhalation applications. Innov. Pharm. Tech. 1(7), 111-116 (2000).
-
(2000)
Innov. Pharm. Tech.
, vol.1
, Issue.7
, pp. 111-116
-
-
Weers, J.G.1
-
9
-
-
33645413962
-
High dose inhaled powder delivery: Challenges and techniques
-
Weers J, Clark A, Challoner P. High dose inhaled powder delivery: challenges and techniques. Proc. Resp. Drug Del. 281-288 (2004).
-
(2004)
Proc. Resp. Drug Del.
, pp. 281-288
-
-
Weers, J.1
Clark, A.2
Challoner, P.3
-
11
-
-
0038826781
-
Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers
-
Newhouse MT, Hirst PH, Duddu SP et al. Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers. Chest 124, 360-366 (2003).
-
(2003)
Chest
, vol.124
, pp. 360-366
-
-
Newhouse, M.T.1
Hirst, P.H.2
Duddu, S.P.3
-
13
-
-
84873343392
-
Dose emission characteristics of placebo PulmoSphere particles are unaffected by a subject's inhalation maneuver
-
Weers JG, Ung K, Le J et al. Dose emission characteristics of placebo PulmoSphere particles are unaffected by a subject's inhalation maneuver. J. Aerosol Med. Pulm. Drug Deliv. 26, 56-68 (2013).
-
(2013)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.26
, pp. 56-68
-
-
Weers, J.G.1
Ung Le K, J.2
-
14
-
-
84896747324
-
Minimizing human factors effects through improved inhaler design
-
Weers JG, Ung K, Chan L et al. Minimizing human factors effects through improved inhaler design. Proc. Resp. Drug Deliv. 217-226 (2012).
-
(2012)
Proc. Resp. Drug Deliv.
, pp. 217-226
-
-
Weers, J.G.1
Ung, K.2
Chan, L.3
-
15
-
-
0034001190
-
Novel lipid-based hollow-porous microparticles as a platform for immunoglobulin delivery to the respiratory tract
-
Bot AI, Tarara TE, Smith DJ et al. Novel lipid-based hollow-porous microparticles as a platform for immunoglobulin delivery to the respiratory tract. Pharm. Res. 17, 274-282 (2000).
-
(2000)
Pharm. Res.
, vol.17
, pp. 274-282
-
-
Bot, A.I.1
Tarara, T.E.2
Smith, D.J.3
-
16
-
-
0034860506
-
Receptor-mediated targeting of spray-dried lipid particles co-formulated with immunoglobulin and loaded with a prototype vaccine
-
Bot AI, Smith DJ, Bot S et al. Receptor-mediated targeting of spray-dried lipid particles co-formulated with immunoglobulin and loaded with a prototype vaccine. Pharm. Res. 18, 971-979 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 971-979
-
-
Bot, A.I.1
Smith, D.J.2
Bot, S.3
-
17
-
-
1542404791
-
Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics
-
Dellamary L, Smith DJ, Bloom A et al. Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics. J. Control. Release 95, 489-500 (2004).
-
(2004)
J. Control. Release
, vol.95
, pp. 489-500
-
-
Dellamary, L.1
Smith, D.J.2
Bloom, A.3
-
18
-
-
0037836974
-
Evaluation of novel aerosol formulations designed for mucosal vaccination against influenza virus
-
Smith DJ, Bot S, Dellamary L et al. Evaluation of novel aerosol formulations designed for mucosal vaccination against influenza virus. Vaccine 21, 2805-2812 (2003).
-
(2003)
Vaccine
, vol.21
, pp. 2805-2812
-
-
Smith, D.J.1
Bot, S.2
Dellamary, L.3
-
19
-
-
0036146484
-
Basic immunological properties of spray-dried lipid microparticles developed for nasal and systemic administration of vaccines
-
Wang L, Bot S, Smith D et al. Basic immunological properties of spray-dried lipid microparticles developed for nasal and systemic administration of vaccines. STP Pharma Sci. 12, 53-61 (2002).
-
(2002)
STP Pharma Sci.
, vol.12
, pp. 53-61
-
-
Wang, L.1
Bot, S.2
Smith, D.3
-
20
-
-
0034019965
-
Hollow porous particles in metered dose inhalers
-
Dellamary LA, Tarara TE, Smith DJ et al. Hollow porous particles in metered dose inhalers. Pharm. Res. 17, 168-174 (2000).
-
(2000)
Pharm. Res.
, vol.17
, pp. 168-174
-
-
Dellamary, L.A.1
Tarara, T.E.2
Smith, D.J.3
-
21
-
-
0002737774
-
Homodispersion technology for HFA suspensions: Particle engineering to reduce dosing variance
-
Weers JG, Tarara TE, Gill H et al. Homodispersion technology for HFA suspensions: particle engineering to reduce dosing variance. Proc. Resp. Drug Del. 91-97 (2000).
-
(2000)
Proc. Resp. Drug Del.
, pp. 91-97
-
-
Weers, J.G.1
Tarara, T.E.2
Gill, H.3
-
22
-
-
0036196011
-
In vivo lung deposition of hollow porous particles from a pressurized metered dose inhaler
-
Hirst PH, Elton RC, Pitcairn GR et al. In vivo lung deposition of hollow porous particles from a pressurized metered dose inhaler. Pharm. Res. 19, 258-264 (2002).
-
(2002)
Pharm. Res.
, vol.19
, pp. 258-264
-
-
Hirst, P.H.1
Elton, R.C.2
Pitcairn, G.R.3
-
23
-
-
21644470926
-
Characterization of suspension-based metered dose inhaler formulations comprised of spray-dried budesonide crystals dispersed in HFA-134a
-
Tarara TE, Hartman M, Gill H et al. Characterization of suspension-based metered dose inhaler formulations comprised of spray-dried budesonide crystals dispersed in HFA-134a. Pharm. Res. 21, 1607-1161 (2004).
-
(2004)
Pharm. Res.
, vol.21
, pp. 1607-1161
-
-
Tarara, T.E.1
Hartman, M.2
Gill, H.3
-
24
-
-
0034751448
-
Liquid dose pulmonary instillation of gentamicin PulmoSpheres formulations: Tissue distribution and pharmacokinetics in rabbits
-
Smith DJ, Gambone LM, Tarara T et al. Liquid dose pulmonary instillation of gentamicin PulmoSpheres formulations: tissue distribution and pharmacokinetics in rabbits. Pharm. Res. 18, 1556-1561 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 1556-1561
-
-
Smith, D.J.1
Gambone, L.M.2
Tarara, T.3
-
25
-
-
0036173627
-
Liquid ventilation with perflubron in the treatment of rats with pneumococcal pneumonia
-
Dickson EW, Heard SO, Tarara TE et al. Liquid ventilation with perflubron in the treatment of rats with pneumococcal pneumonia. Crit. Care Med. 30, 393-395 (2002).
-
(2002)
Crit. Care Med.
, vol.30
, pp. 393-395
-
-
Dickson, E.W.1
Heard, S.O.2
Tarara, T.E.3
-
26
-
-
0141780877
-
Prevention of descending pneumonia in rats with perflubron-delivered tobramycin
-
Dickson EW, Doern GV, Trevino L et al. Prevention of descending pneumonia in rats with perflubron-delivered tobramycin. Acad. Emerg. Med. 10, 1019-1023 (2003).
-
(2003)
Acad. Emerg. Med.
, vol.10
, pp. 1019-1023
-
-
Dickson, E.W.1
Doern, G.V.2
Trevino, L.3
-
27
-
-
80053176667
-
Novel cosuspension metered-dose inhalers for combination therapy of chronic obstructive pulmonary disease and asthma
-
Lechuga-Ballesteros D, Noga B, Vehring R et al. Novel cosuspension metered-dose inhalers for combination therapy of chronic obstructive pulmonary disease and asthma. Future Med. Chem. 3, 1703-1718 (2011).
-
(2011)
Future Med. Chem.
, vol.3
, pp. 1703-1718
-
-
Lechuga-Ballesteros, D.1
Noga, B.2
Vehring, R.3
-
28
-
-
84867755100
-
Cosuspensions of microcrystals and engineered microparticles for uniform and efficient delivery of respiratory therapeutics from pressurized metered dose inhalers
-
Vehring R, Lechuga-Ballesteros D, Joshi V et al. Cosuspensions of microcrystals and engineered microparticles for uniform and efficient delivery of respiratory therapeutics from pressurized metered dose inhalers. Langmuir 28, 15015-15023 (2012).
-
(2012)
Langmuir
, vol.28
, pp. 15015-15023
-
-
Vehring, R.1
Lechuga-Ballesteros, D.2
Joshi, V.3
-
29
-
-
80053198273
-
Poster: A novel cosuspension MDI platform: Scientific foundations of mono, dual and triple combination products
-
Lechuga-Ballesteros D, Vehring R, Dwivedi SK. Poster: a novel cosuspension MDI platform: scientific foundations of mono, dual and triple combination products. Proc. RDD Europe 101-111 (2011).
-
(2011)
Proc. RDD Europe
, pp. 101-111
-
-
Lechuga-Ballesteros, D.1
Vehring, R.2
Dwivedi, S.K.3
-
30
-
-
80053204735
-
Poster: Performance advantages of Pearl co-suspension formulations for manufacturing of metered dose inhalers
-
Cummings RH, Joshi V, Lechuga-Ballesteros D et al. Poster: performance advantages of Pearl co-suspension formulations for manufacturing of metered dose inhalers. Proc. RDD Europe 387-390 (2011).
-
(2011)
Proc. RDD Europe
, pp. 387-390
-
-
Cummings, R.H.1
Joshi, V.2
Lechuga-Ballesteros, D.3
-
31
-
-
84867800039
-
Product performance, stability, and dose proportionality of glycopyrrolate metered dose inhaler with sub-microgram doses using co-suspension technology
-
Noga B, Cummings RH, Joshi V et al. Product performance, stability, and dose proportionality of glycopyrrolate metered dose inhaler with sub-microgram doses using co-suspension technology. Respir. Drug Deliv. 2, 645-648 (2012).
-
(2012)
Respir. Drug Deliv.
, vol.2
, pp. 645-648
-
-
Noga, B.1
Cummings, R.H.2
Joshi, V.3
-
32
-
-
85157092681
-
Dose proportionality in a triple therapy co-suspension pMDI with multiple strengths of an inhaled corticosteroid
-
Lechuga-Ballesteros D, Schroeder J, Alluri S et al. Dose proportionality in a triple therapy co-suspension pMDI with multiple strengths of an inhaled corticosteroid. RDD Europe 2, 339-342 (2013).
-
(2013)
RDD Europe
, vol.2
, pp. 339-342
-
-
Lechuga-Ballesteros, D.1
Schroeder, J.2
Alluri, S.3
-
33
-
-
84858666186
-
Prophylactic efficacy of single dose pulmonary administration of amphotericin B inhalation powder in a guinea pig model of invasive pulmonary aspergillosis
-
Kirkpatrick WR, Najvar LK, Vallor AC et al. Prophylactic efficacy of single dose pulmonary administration of amphotericin B inhalation powder in a guinea pig model of invasive pulmonary aspergillosis. J. Antimicrob. Chemother. 67, 970-976 (2012).
-
(2012)
J. Antimicrob. Chemother.
, vol.67
, pp. 970-976
-
-
Kirkpatrick, W.R.1
Najvar, L.K.2
Vallor, A.C.3
-
34
-
-
79961039597
-
Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere technology
-
Geller DE, Weers J, Heuerding S. Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere technology. J. Aerosol Med. Pulm. Drug Deliv. 24, 175-182 (2011).
-
(2011)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.24
, pp. 175-182
-
-
Geller, D.E.1
Weers, J.2
Heuerding, S.3
-
35
-
-
79961060764
-
Aerosol performance of tobramycin inhalation powder
-
2010
-
Haynes A, Nakamura J, Heng C et al. Aerosol performance of tobramycin inhalation powder. Proc. Resp. Drug Deliv. 701-706 (2010) (2010).
-
(2010)
Proc. Resp. Drug Deliv.
, pp. 701-706
-
-
Haynes, A.1
Nakamura, J.2
Heng, C.3
-
36
-
-
84873724393
-
Device engineering insights into TOBI Podhaler: A development case study of high efficiency powder delivery to cystic fibrosis patients
-
Maltz D, Paboojian SJ. Device engineering insights into TOBI Podhaler: a development case study of high efficiency powder delivery to cystic fibrosis patients. RDD Europe 55-66 (2011).
-
(2011)
RDD Europe
, pp. 55-66
-
-
Maltz, D.1
Paboojian, S.J.2
-
37
-
-
84923149469
-
In vitro aerosol delivery performance of tobramycin powder for inhalation (TOBI Podhaler) using inspiratory flow rates from cystic fibrosis patients (abstract)
-
Salt Lake City, UT, USA 17-19 September 2013
-
Haynes A, Ament B, Heng C et al. In vitro aerosol delivery performance of tobramycin powder for inhalation (TOBI Podhaler) using inspiratory flow rates from cystic fibrosis patients (abstract). Presented at: The North American Cystic Fibrosis Conference, Salt Lake City, UT, USA, 17-19 September 2013.
-
The North American Cystic Fibrosis Conference
-
-
Haynes, A.1
Ament, B.2
Heng, C.3
-
38
-
-
34247193128
-
Novel tobramycin inhalation powder in cystic fibrosis subjects: Pharmacokinetics and safety
-
Geller DE, Konstan MW, Smith J et al. Novel tobramycin inhalation powder in cystic fibrosis subjects: pharmacokinetics and safety. Pediatr. Pulmonol. 42, 307-313 (2007).
-
(2007)
Pediatr. Pulmonol.
, vol.42
, pp. 307-313
-
-
Geller, D.E.1
Konstan, M.W.2
Smith, J.3
-
39
-
-
78651412529
-
Safety, efficacy, and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial
-
Konstan M, Flume PA, Kappler M et al. Safety, efficacy, and convenience of tobramycin inhalation powder in cystic fibrosis patients: the EAGER trial. J. Cyst. Fibrosis 10, 54-61 (2011).
-
(2011)
J. Cyst. Fibrosis
, vol.10
, pp. 54-61
-
-
Konstan, M.1
Flume, P.A.2
Kappler, M.3
-
40
-
-
79951840468
-
Tobramycin inhalation powder for P. Aeruginosa infection in cystic fibrosis: The EVOLVE trial
-
Konstan M, Geller DE, Minic P et al. Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: the EVOLVE trial. Pediatr. Pulmonol. 46, 230-238 (2011).
-
(2011)
Pediatr. Pulmonol.
, vol.46
, pp. 230-238
-
-
Konstan, M.1
Geller, D.E.2
Minic, P.3
-
41
-
-
84880473914
-
Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: The randomized EDIT trial
-
Galeva I, Konstan MW, Higgins M et al. Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: the randomized EDIT trial. Curr. Med. Res. Opin. 29(8), 947-956 (2013).
-
(2013)
Curr. Med. Res. Opin.
, vol.29
, Issue.8
, pp. 947-956
-
-
Galeva, I.1
Konstan, M.W.2
Higgins, M.3
-
42
-
-
84888992940
-
Tobramycin inhalation powder in cystic fibrosis: Response by age group
-
doi:10.4187/respcare.02264, Epub ahead of print
-
Geller DE, Nasr SJ, Piggott S et al. Tobramycin inhalation powder in cystic fibrosis: response by age group. Respir. Care doi:10.4187/respcare.02264 (2013) (Epub ahead of print).
-
(2013)
Respir. Care
-
-
Geller, D.E.1
Nasr, S.J.2
Piggott, S.3
-
43
-
-
84889073216
-
Tobramycin administered by the TOBI Podhaler for persons with cystic fibrosis: A review
-
Vandevanter DR, Geller DE. Tobramycin administered by the TOBI Podhaler for persons with cystic fibrosis: a review. Med. Devices (Auckland) 4, 179-188 (2011).
-
(2011)
Med. Devices (Auckland)
, vol.4
, pp. 179-188
-
-
Vandevanter, D.R.1
De, G.2
-
44
-
-
80053377162
-
Tobramycin inhalation powder: A novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis
-
Parkins MD, Elborn JS: Tobramycin inhalation powder: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis. Expert Rev. Respir. Med. 5, 609-622 (2011).
-
(2011)
Expert Rev. Respir. Med.
, vol.5
, pp. 609-622
-
-
Parkins, M.D.1
Elborn, J.S.2
-
45
-
-
84877094276
-
A novel high-payload dry powder formulation of ciprofloxacin for management of chronic lung infections
-
Gupta A, Tarara T, Miller D et al. A novel high-payload dry powder formulation of ciprofloxacin for management of chronic lung infections. AAPS J. 13(S2), R6156 (2011).
-
(2011)
AAPS J.
, vol.13
, Issue.2
-
-
Gupta, A.1
Tarara, T.2
Miller, D.3
-
46
-
-
84878695314
-
Inhalation of a dry powder ciprofloxacin formulation in healthy subjects: A Phase i st udy
-
Stass H, Nagelschmitz J, Willmann S et al. Inhalation of a dry powder ciprofloxacin formulation in healthy subjects: a Phase I st udy. Clin. Drug Investig. 33(6), 419-427. (2013).
-
(2013)
Clin. Drug Investig.
, vol.33
, Issue.6
, pp. 419-419
-
-
Stass, H.1
Nagelschmitz, J.2
Willmann, S.3
-
47
-
-
84885841052
-
Tolerability and pharmacokinetic properties of ciprofloxacin dry powder for inhalation in patients with cystic fibrosis: A Phase I, randomized, dose-escalation study
-
Stass H, Weimann B, Nagelschmitz J et al. Tolerability and pharmacokinetic properties of ciprofloxacin dry powder for inhalation in patients with cystic fibrosis: a Phase I, randomized, dose-escalation study. Clin. Ther. 35 (10), 1571-1581 (2013).
-
(2013)
Clin. Ther.
, vol.35
, Issue.10
, pp. 1571-1581
-
-
Stass, H.1
Weimann, B.2
Nagelschmitz, J.3
-
48
-
-
84876214711
-
Ciprofloxacin DPI in non-cystic fibrosis bronchiectasis: A Phase II randomized study
-
Antoniu S, Azoicai D. Ciprofloxacin DPI in non-cystic fibrosis bronchiectasis: a Phase II randomized study. Expert Opin. Invest. Drugs 22(5), 671-673 (2013).
-
(2013)
Expert Opin. Invest. Drugs
, vol.22
, Issue.5
, pp. 671-673
-
-
Antoniu, S.1
Azoicai, D.2
-
49
-
-
84877093743
-
Ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis: A Phase II randomised study
-
Wilson R, Welte T, Polverino E et al. Ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis: a Phase II randomised study. Eur. Resp. J. 41, 1107-1115 (2013).
-
(2013)
Eur. Resp. J.
, vol.41
, pp. 1107-1115
-
-
Wilson, R.1
Welte, T.2
Polverino, E.3
-
50
-
-
84877089118
-
Safety, tolerability and pharmacokinetics of ciprofloxacin dry powder for inhalation in patients with mild to moderate chronic obstructive pulmonary disease: A randomized controlled trial
-
Tokimatsu I, Hiramatsu K, Morimoto T et al. Safety, tolerability and pharmacokinetics of ciprofloxacin dry powder for inhalation in patients with mild to moderate chronic obstructive pulmonary disease: a randomized controlled trial. Am. J. Respir.Crit. Care Med. 183, A3105 (2011).
-
(2011)
Am. J. Respir.Crit. Care Med.
, vol.183
-
-
Tokimatsu, I.1
Hiramatsu, K.2
Morimoto, T.3
-
51
-
-
80053210929
-
Assessment of safety and pharmacokinetic profile of a novel fixed dose combination of glycopyrrolate and formoterol HFA MDI in healthy volunteers
-
Marjason J, Orevillo CJ, St Rose E et al. Assessment of safety and pharmacokinetic profile of a novel fixed dose combination of glycopyrrolate and formoterol HFA MDI in healthy volunteers. Am. J. Respir. Crit. Care Med. 181, A4455 (2010).
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.181
-
-
Marjason, J.1
Orevillo, C.J.2
St Rose, E.3
-
52
-
-
80053193731
-
Novel combination of glycopyrrolate and formoterol MDI (GFF-MDI) provides superior bronchodilation compared with its components alone, tiotropium DPI, and formoterol DPI in a randomized, double-blind, placebo-controlled Phase IIb study in patients with COPD
-
Reisner C, Fogarty C, Spangenthal S et al. Novel combination of glycopyrrolate and formoterol MDI (GFF-MDI) provides superior bronchodilation compared with its components alone, tiotropium DPI, and formoterol DPI in a randomized, double-blind, placebo-controlled Phase IIb study in patients with COPD. Am. J. Respir. Crit. Care Med. 183, A6435 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
-
-
Reisner, C.1
Fogarty, C.2
Spangenthal, S.3
-
60
-
-
85157209110
-
-
US provisional application (US61/784865) (
-
Weers JG, Huang D, Miller DP et al.: US provisional application (US61/784865) (2013).
-
, Issue.2013
-
-
Weers, J.G.1
Huang, D.2
Miller, D.P.3
-
64
-
-
0003138648
-
Design and engineering of oxygen-delivering fluorocarbon emulsions
-
Benita S (Ed.) Harwood Academic Publishers, Amsterdam, The Netherlands, 235-333
-
Krafft MP, Riess JG, Weers JG. The Design and Engineering of Oxygen-Delivering Fluorocarbon Emulsions. In: Submicron Emulsions in Drug Targeting and Delivery. Benita S (Ed.). Harwood Academic Publishers, Amsterdam, The Netherlands, 235-333 (1998).
-
(1998)
Submicron Emulsions in Drug Targeting and Delivery
-
-
Krafft, M.P.1
Riess, J.G.2
Weers, J.G.3
-
65
-
-
0037126053
-
Troja n particles: Large porous carriers of nanoparticles for drug delivery
-
Tsapis N, Bennett D, Jackson B et al. Troja n particles: large porous carriers of nanoparticles for drug delivery. Proc. Natl Acad. Sci. USA 99, 12001-12005 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 12001-12005
-
-
Tsapis, N.1
Bennett, D.2
Jackson, B.3
-
66
-
-
0026658631
-
Filter paper equilibration as a novel technique for in vitro studies of the composition of airway surface fluid
-
Joris L, Quinton PM. Filter paper equilibration as a novel technique for in vitro studies of the composition of airway surface fluid. Am. J. Physiol. 263, L243-L248 (1992).
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Joris, L.1
Quinton, P.M.2
-
67
-
-
0029838499
-
Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome
-
Leach CL, Greenspan JS, Rubenstein SD et al. Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. N. Eng. J. Med. 335, 761-767 (1996).
-
(1996)
N. Eng. J. Med.
, vol.335
, pp. 761-767
-
-
Leach, C.L.1
Greenspan, J.S.2
Rubenstein, S.D.3
-
68
-
-
0030045040
-
Initial experience with partial liquid ventilation in pediatric patients with the acute respiratory distress syndrome
-
Gauger PG, Pranikoff T, Schreiner RJ et al. Initial experience with partial liquid ventilation in pediatric patients with the acute respiratory distress syndrome. JAMA 275(5), 383-389 (1996).
-
(1996)
JAMA
, vol.275
, Issue.5
, pp. 383-389
-
-
Gauger, P.G.1
Pranikoff, T.2
Schreiner, R.J.3
-
69
-
-
85157243894
-
Partial liquid ventilation in patients with ARDS: A multicenter Phase I-II trial
-
Hirschl RB, Conrad S, Kaiser R et al. Partial liquid ventilation in patients with ARDS: a multicenter Phase I-II trial. Adult PLV study group. Crit. Care Med. 24(1), 16-22 (1996).
-
(1996)
Adult PLV Study Group. Crit. Care Med.
, vol.24
, Issue.1
, pp. 16-22
-
-
Hirschl, R.B.1
Conrad, S.2
Kaiser, R.3
-
70
-
-
84886129576
-
Novel Particle Production Technologies for Inhalation Products (Chapter 4)
-
Colombo P, Traini D, Buttini F (Eds) John Wiley & Sons, Ltd, Chichester, UK (
-
Chan HK, Kwok PCL. Novel Particle Production Technologies for Inhalation Products (Chapter 4). In: Inhalation Drug Delivery: Techniques and Products. Colombo P, Traini D, Buttini F (Eds). John Wiley & Sons, Ltd, Chichester, UK (2013).
-
(2013)
Inhalation Drug Delivery: Techniques and Products
-
-
Chan, H.K.1
Kwok, P.C.L.2
-
72
-
-
20044363723
-
The cohesive-adhesive balances in dry powder inhaler formulations I: Direct quantification by atomic force microscopy
-
Begat P, Morton DAV, Staniforth JN. The cohesive-adhesive balances in dry powder inhaler formulations I: direct quantification by atomic force microscopy. Pharm. Res. 21, 1591-1597 (2004).
-
(2004)
Pharm. Res.
, vol.21
, pp. 1591-1597
-
-
Begat, P.1
Dav, M.2
Staniforth, J.N.3
-
73
-
-
0342657112
-
The inf luence of carrier morphology on drug delivery by dry powder inhalers
-
Zeng XM, Martin GP, Marriott C, Pritchard J. The inf luence of carrier morphology on drug delivery by dry powder inhalers. Int. J. Pharm. 200, 93-106 (2000).
-
(2000)
Int. J. Pharm.
, vol.200
, pp. 93-106
-
-
Zeng, X.M.1
Martin, G.P.2
Marriott, C.3
Pritchard, J.4
-
75
-
-
85157189609
-
-
US5437272
-
Fuhrman BP: US5437272 (1995).
-
(1995)
-
-
Fuhrman, B.P.1
-
77
-
-
67649389317
-
Porous particles for inhalation: The science behind their improved dispersibility
-
Dunbar C. Porous particles for inhalation: the science behind their improved dispersibility. Proc. Resp. Drug Deliv. 10, 307-313 (2006).
-
(2006)
Proc. Resp. Drug Deliv.
, vol.10
, pp. 307-313
-
-
Dunbar, C.1
-
78
-
-
84896768425
-
Appealing to users-designing inhalers to maximize compliance and minimize misuse
-
Dixon J, Simpson I. Appealing to users-designing inhalers to maximize compliance and minimize misuse. RDD Europe 117-127 (2009).
-
(2009)
RDD Europe
, pp. 117-127
-
-
Dixon, J.1
Simpson, I.2
-
79
-
-
33846076698
-
Degree of throat deposition can explain the variability in lung deposition of inhaled drugs
-
Borgström L, Olsson B, Thorsson L. Degree of throat deposition can explain the variability in lung deposition of inhaled drugs. J. Aerosol Med. Pulm. Drug Deliv. 19, 473-483 (2006).
-
(2006)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.19
, pp. 473-483
-
-
Borgström, L.1
Olsson, B.2
Thorsson, L.3
-
80
-
-
0035513523
-
Pharmacokinetics and systemic activity of fluticasone via Diskus and pMDI, and of budesonide via Turbuhaler
-
Thorsson L, Edsbäcker S, Källén A, Lfdahl C-G. Pharmacokinetics and systemic activity of fluticasone via Diskus and pMDI, and of budesonide via Turbuhaler. Br. J. Clin. Pharmacol. 52, 529-538 (2001).
-
(2001)
Br. J. Clin. Pharmacol.
, vol.52
, pp. 529-538
-
-
Thorsson, L.1
Edsbäcker, S.2
Källén, A.3
Lfdahl, C.-G.4
-
81
-
-
84887786913
-
Dynamic inspiratory flow characteristics through the T-326 dry powder inhaler in cystic fibrosis patients
-
Pavkov R, Geller DE, Ament B et al. Dynamic inspiratory flow characteristics through the T-326 dry powder inhaler in cystic fibrosis patients. RDD Europe 325-328 (2013).
-
(2013)
RDD Europe
, pp. 325-328
-
-
Pavkov, R.1
Geller, D.E.2
Ament, B.3
-
82
-
-
78650192172
-
Effects of device design on patient compliance: Comparing the same drug in different devices
-
Chrystyn H. Effects of device design on patient compliance: comparing the same drug in different devices. RDD Europe 105-116 (2009).
-
(2009)
RDD Europe
, pp. 105-116
-
-
Chrystyn, H.1
-
83
-
-
79958008114
-
What the pulmonary specialist should know about the new inhalation therapies
-
Laube BL, Janssens HM, De Jongh FHC et al. What the pulmonary specialist should know about the new inhalation therapies. Eur. Resp. J. 37(6), 1308-1331 (2011).
-
(2011)
Eur. Resp. J.
, vol.37
, Issue.6
, pp. 1308-1331
-
-
Laube, B.L.1
Janssens, H.M.2
De Jongh Fhc3
-
84
-
-
0028354478
-
Lung deposition of budesonide inhaled via Turbuhaler: A comparison with terbutaline sulphate in normal subjects
-
Borgström L, Bondesson E, Moren F et al. Lung deposition of budesonide inhaled via Turbuhaler: a comparison with terbutaline sulphate in normal subjects. Eur. Respir. J. 7, 69-73 (1994).
-
(1994)
Eur. Respir. J.
, vol.7
, pp. 69-73
-
-
Borgström, L.1
Bondesson, E.2
Moren, F.3
-
85
-
-
78650197961
-
An assessment of the in vitro deposition of aerosolized drugs from a combination dry powder inhaler using the Andersen cascade impactor (ACI)
-
Taki M, Zeng XM, Mariott C, Martin G. An assessment of the in vitro deposition of aerosolized drugs from a combination dry powder inhaler using the Andersen cascade impactor (ACI). Proc. Respir. Drug Deliv. 655-657 (2006).
-
(2006)
Proc. Respir. Drug Deliv.
, pp. 655-657
-
-
Taki, M.1
Zeng, X.M.2
Mariott, C.3
Martin, G.4
-
87
-
-
79251481134
-
Maillard reactions in pharmaceutical formulations and human health
-
Newton DW. Maillard reactions in pharmaceutical formulations and human health. Int. J. Pharm. Compd. 15(1), 32-40 (2011).
-
(2011)
Int. J. Pharm. Compd.
, vol.15
, Issue.1
, pp. 32-40
-
-
Newton, D.W.1
-
88
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW, FeeneyPJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 23, 3-25 (1997).
-
(1997)
Adv. Drug Deliv. Rev.
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
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