Liquid dose pulmonary instillation of gentamicin pulmoSpheres® formulations: Tissue distribution and pharmacokinetics in rabbits

Pharmaceutical Research

Volumn 18, Issue 11, 2001, Pages 1556-1561

  Smith, D J ^a   Gambone, L M ^a   Tarara, T ^a,b   Meays, D R ^a   Dellamary, L A ^a   Woods, C M ^a   Weers, J ^a,b  

^a Alliance Pharmaceutical Corporation   (United States)

^b NEKTAR THERAPEUTICS   (United States)

Author keywords

Drug delivery; Gentamicin; LiquiVent ; Lung; Perflubron; PulmoSpheres

Indexed keywords

ANTIBIOTIC AGENT; DRUG VEHICLE; EPC 3; GENTAMICIN; GENTAMICIN PULMOSPHERES; GLUCOSE; OLEATE SODIUM; PERFLUOROOCTYL BROMIDE; PHOSPHATIDYLCHOLINE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG INSTILLATION; INFECTION; LIQUID; LUNG; NONHUMAN; PRIORITY JOURNAL; RABBIT; TISSUE DISTRIBUTION;

ADMINISTRATION, INHALATION; ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; BIOLOGICAL ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXCIPIENTS; FLUOROCARBONS; GENTAMICINS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; LUNG; MICROSPHERES; PHARMACEUTICAL SOLUTIONS; RABBITS; TISSUE DISTRIBUTION;

EID: 0034751448     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013078330485     Document Type: Article

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