Azobenzene switch with a long-lived cis-state to photocontrol the enzyme activity of a histone deacetylase-like amidohydrolase

Biological Chemistry

Volumn 395, Issue 4, 2014, Pages 401-412

  Korbus, Michael ^a   Balasubramanian, Ganesh ^b,c   Müller Plathe, Florian ^b   Kolmar, Harald ^b   Meyer Almes, Franz Josef ^a  

^a DARMSTADT UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^c Iowa State University   (United States)

Author keywords

deacetylation; external stimulus: HDAH; photochromism; photoswitch; protein engineering

Indexed keywords

4 PHENYLAZOMALEINANIL; AMIDASE; ASPARTIC ACID; AZOBENZENE DERIVATIVE; CYSTEINE; HISTONE DEACETYLASE; HISTONE DEACETYLASE LIKE AMIDOHYDROLASE; UNCLASSIFIED DRUG; ZINC ION; AZO COMPOUND; AZOBENZENE;

ALCALIGENES; ARTICLE; BIOCATALYST; BORDETELLA; CATALYSIS; CHEMICAL MODIFICATION; CIS ISOMER; CIS TRANS ISOMERISM; CRYSTAL STRUCTURE; DEACETYLATION; ENZYME ACTIVITY; HYDROGEN BOND; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IN VITRO STUDY; ISOMERIZATION; MICHAELIS MENTEN KINETICS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PHOTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; SURFACE PROPERTY; THERMODYNAMICS; ULTRAVIOLET RADIATION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC VARIABILITY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; STEREOISOMERISM; TEMPERATURE; X RAY CRYSTALLOGRAPHY;

AMIDOHYDROLASES; AZO COMPOUNDS; BORDETELLA; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; GENETIC VARIATION; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHOTOCHEMICAL PROCESSES; STEREOISOMERISM; TEMPERATURE;

EID: 84896787227     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2013-0246     Document Type: Article

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