Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  O'Hara, Laura ^a   York, Jean Philippe ^b   Zhang, Pumin ^b   Smith, Lee B ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CRE RECOMBINASE; GREEN FLUORESCENT PROTEIN; TESTOSTERONE; YELLOW FLUORESCENT PROTEIN;

ADRENAL CORTEX; ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; CYP11A1 GENE; ENDOCRINE CELL; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENE LOSS; GENE TARGETING; HETEROZYGOTE; HOMOZYGOSITY; KNOCKOUT MOUSE; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PERINATAL PERIOD; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; RHOMBENCEPHALON; SERTOLI CELL; STEROIDOGENESIS; TESTOSTERONE BLOOD LEVEL; THECA CELL; TRANSGENIC MOUSE;

ANIMALS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; FEMALE; GENE EXPRESSION; GENE ORDER; GENE TARGETING; GREEN FLUORESCENT PROTEINS; INTEGRASES; MALE; MICE; MICE, KNOCKOUT; OVARY; PHENOTYPE; TESTIS;

EID: 84896777438     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084541     Document Type: Article

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