Impaired spatial learning and memory after sevoflurane-nitrous oxide anesthesia in aged rats is associated with down-regulated cAMP/CREB signaling

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Xiong, Wan Xia ^a   Zhou, Guo Xia ^a   Wang, Bei ^a   Xue, Zhang Gang ^a   Wang, Lu ^a   Sun, Hui Chuan ^a   Ge, Sheng Jin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NITROUS OXIDE; OXYGEN; SEVOFLURANE;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; LEARNING DISORDER; MEMORY; MEMORY DISORDER; MORRIS WATER MAZE TEST; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPATIAL LEARNING;

ANESTHETICS, INHALATION; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; MALE; MAZE LEARNING; MEMORY; METHYL ETHERS; NITROUS OXIDE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPACE PERCEPTION;

EID: 84896740207     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079408     Document Type: Article

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