Effectiveness of novel 5-(5-amino-1-aryl-1H-pyrazol-4-yl)-1H-tetrazole derivatives against promastigotes and amastigotes of leishmania amazonensis

Chemical Biology and Drug Design

Volumn 83, Issue 3, 2014, Pages 272-277

  Dos Santos Faióes, Viviane ^a   Leon, Leonor L ^a   Canto Cavalheiro, Marilene M ^a   Torres Santos, Eduardo C ^a   Bernardino, Alice M R ^b   Vegi, Percilene F ^b   Dos Santos, Maurício S ^c  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c FEDERAL UNIVERSITY OF ITAJUBÁ   (Brazil)

Author keywords

antileishmanial activity; Leishmania amazonensis; tetrazole derivatives

Indexed keywords

5 (5 AMINO 1 PHENYL 1H PYRAZOL 4 YL) 1H TETRAZOLE; 5 [5 AMINO 1 (2 FLUOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (2' CHLOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (2',4' DICHLOROPHENYL) 1H PYRAZOLE 4 YL] TETRAZOLE; 5 [5 AMINO 1 (2',6' DICHLOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (3' BROMOPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (3' CHLOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (3' FLUOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (3',4' DICHLOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (3',5' DICHLOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (4' CHLOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; 5 [5 AMINO 1 (4' FLUOROPHENYL) 1H PYRAZOLE 4 YL] 1H TETRAZOLE; ANTILEISHMANIAL AGENT; HYDROGEN; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CYCLOADDITION; CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HOST CELL; IC 50; INFRARED SPECTROSCOPY; LEISHMANIA; MACROPHAGE; MASS SPECTROMETRY; MICHAEL ADDITION; NONHUMAN; PARASITE LOAD; PRIORITY JOURNAL; PROMASTIGOTE; PROTON NUCLEAR MAGNETIC RESONANCE;

LEISHMANIA AMAZONENSIS; MURINAE;

ANTILEISHMANIAL ACTIVITY; LEISHMANIA AMAZONENSIS; TETRAZOLE DERIVATIVES;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; CELL SURVIVAL; LEISHMANIA; MICE; MICE, INBRED BALB C; TETRAZOLES;

EID: 84896731967     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12235     Document Type: Article

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