Insulin/IGF-I signaling pathways enhances tumor cell invasion through bisecting GlcNAc N-glycans modulation. An interplay with E-cadherin

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  De Freitas Junior, Julio Cesar Madureira ^a   Carvalho, Sandra ^b   Dias, Ana M ^b   Oliveira, Patrícia ^b   Cabral, Joana ^b   Seruca, Raquel ^b,c   Oliveira, Carla ^b,c   Morgado Díaz, José Andrés ^a   Reis, Celso A ^b,c   Pinho, Salomé S ^b  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^b UNIVERSITY OF PORTO   (Portugal)

^c University of Porto   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPEPTIDASE; INSULIN; INSULIN RECEPTOR; N ACETYLGLUCOSAMINE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UVOMORULIN;

ARTICLE; CANCER CELL; CANCER GROWTH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GLYCOSYLATION; HUMAN; HUMAN CELL; MESENCHYME; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR INVASION;

ACETYLGLUCOSAMINE; BETA CATENIN; BLOTTING, WESTERN; CADHERINS; CELL LINE, TUMOR; CYTOPLASM; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOSYLATION; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; NEOPLASM INVASIVENESS; PHOSPHORYLATION; POLYSACCHARIDES; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84896731020     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081579     Document Type: Article

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