메뉴 건너뛰기




Volumn 25, Issue 4, 2014, Pages 255-261

Visual-spatial learning impairments are associated with hippocampal PSD-95 protein dysregulation in a mouse model of fragile X syndrome

Author keywords

Fragile X syndrome; Hebb Williams mazes; hippocampus; visual spatial learning and memory; western blot

Indexed keywords

BETA TUBULIN; FRAGILE X MENTAL RETARDATION PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95;

EID: 84896730219     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000087     Document Type: Article
Times cited : (14)

References (26)
  • 1
    • 0036301947 scopus 로고    scopus 로고
    • A decade of molecular studies of fragile X syndrome
    • O'Donnell WT, Warren ST. A decade of molecular studies of fragile X syndrome. Annu Rev Neurosci 2002; 25:315-338.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 315-338
    • O'Donnell, W.T.1    Warren, S.T.2
  • 2
    • 58749083245 scopus 로고    scopus 로고
    • A comparative neuropsychological test battery differentiates cognitive signatures of Fragile X and Down syndrome. J
    • Intellect
    • Kogan CS, Boutet I, Cornish K, Graham GE, Berry-Kravis E, Drouin A, et al. A comparative neuropsychological test battery differentiates cognitive signatures of Fragile X and Down syndrome. J Intellect Disabil Res 2009; 53:125-142.
    • (2009) Disabil Res , vol.53 , pp. 125-142
    • Kogan, C.S.1    Boutet, I.2    Cornish, K.3    Graham, G.E.4    Berry-Kravis, E.5    Drouin, A.6
  • 3
    • 75749155413 scopus 로고    scopus 로고
    • A comparative study of the performance of individuals with fragile X syndrome and Fmr1 knockout mice on Hebb-Williams mazes
    • MacLeod LS, Kogan CS, Collin CA, Berry-Kravis E, Messier C, Gandhi R. A comparative study of the performance of individuals with fragile X syndrome and Fmr1 knockout mice on Hebb-Williams mazes. Genes Brain Behav 2010; 9:53-64.
    • (2010) Genes Brain Behav , vol.9 , pp. 53-64
    • Macleod, L.S.1    Kogan, C.S.2    Collin, C.A.3    Berry-Kravis, E.4    Messier, C.5    Gandhi, R.6
  • 5
    • 0037372019 scopus 로고    scopus 로고
    • Of mice and the fragile X syndrome
    • Kooy RF. Of mice and the fragile X syndrome. Tr e n d s G e n e t 2003; 19:148-154.
    • (2003) Tr e N D S G e N e T , vol.19 , pp. 148-154
    • Kooy, R.F.1
  • 6
    • 0027300283 scopus 로고
    • Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain
    • Abitbol M, Menini C, Delezoide AL, Rhyner T, Vekemans M, Mallet J. Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain. Nat Genet 1993; 4:147-153.
    • (1993) Nat Genet , vol.4 , pp. 147-153
    • Abitbol, M.1    Menini, C.2    Delezoide, A.L.3    Rhyner, T.4    Vekemans, M.5    Mallet, J.6
  • 7
    • 0027397928 scopus 로고
    • Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome
    • Hinds HL, Ashley CT, Sutcliffe JS, Nelson DL, Warren ST, Housman DE, et al. Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome. Nat Genet 1993; 3:36-43.
    • (1993) Nat Genet , vol.3 , pp. 36-43
    • Hinds, H.L.1    Ashley, C.T.2    Sutcliffe, J.S.3    Nelson, D.L.4    Warren, S.T.5    Housman, D.E.6
  • 8
    • 77955139512 scopus 로고    scopus 로고
    • Male and female Fmr1 knockout mice on C57 albino background exhibit spatial learning and memory impairments
    • Baker KB, Wray SP, Ritter R, Mason S, Lanthorn TH, Savelieva KV. Male and female Fmr1 knockout mice on C57 albino background exhibit spatial learning and memory impairments. Genes Brain Behav 2010; 9:562-574.
    • (2010) Genes Brain Behav , vol.9 , pp. 562-574
    • Baker, K.B.1    Wray, S.P.2    Ritter, R.3    Mason, S.4    Lanthorn, T.H.5    Savelieva, K.V.6
  • 9
    • 33747358251 scopus 로고    scopus 로고
    • Lesions of the dorsal hippocampus or parietal cortex differentially affect spatial information processing
    • Rogers JL, Kesner RP. Lesions of the dorsal hippocampus or parietal cortex differentially affect spatial information processing. Behav Neurosci 2006; 120:852-860.
    • (2006) Behav Neurosci , vol.120 , pp. 852-860
    • Rogers, J.L.1    Kesner, R.P.2
  • 10
    • 0024990024 scopus 로고
    • Hippocampal and prefrontal cortex contributions to learning and memory: Analysis of lesion and aging effects on maze learning in rats
    • Winocur G, Moscovitch M. Hippocampal and prefrontal cortex contributions to learning and memory: analysis of lesion and aging effects on maze learning in rats. Behav Neurosci 1990; 104:544-551.
    • (1990) Behav Neurosci , vol.104 , pp. 544-551
    • Winocur, G.1    Moscovitch, M.2
  • 11
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • Malenka RC, Bear MF. LTP and LTD: an embarrassment of riches. Neuron 2004; 44:5-21.
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 13
    • 77951531718 scopus 로고    scopus 로고
    • Excitation control: Balancing PSD-95 function at the synapse
    • Keith D, El-Husseini A. Excitation control: balancing PSD-95 function at the synapse. Front Mol Neurosci 2008; 1:4.
    • (2008) Front Mol Neurosci , vol.1 , pp. 4
    • Keith, D.1    El-Husseini, A.2
  • 15
    • 55049085418 scopus 로고    scopus 로고
    • Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity
    • Steiner P, Higley MJ, Xu W, Czervionke BL, Malenka RC, Sabatini BL. Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity. Neuron 2008; 60:788-802.
    • (2008) Neuron , vol.60 , pp. 788-802
    • Steiner, P.1    Higley, M.J.2    Xu, W.3    Czervionke, B.L.4    Malenka, R.C.5    Sabatini, B.L.6
  • 17
    • 17844372504 scopus 로고    scopus 로고
    • From mRNP trafficking to spine dysmorphogenesis: The roots of fragile X syndrome
    • Bagni C, Greenough WT. From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci 2005; 6:376-387.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 376-387
    • Bagni, C.1    Greenough, W.T.2
  • 18
    • 34249064936 scopus 로고    scopus 로고
    • Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome
    • Muddashetty RS, Kelic S, Gross C, Xu M, Bassell GJ. Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. J Neurosci 2007; 27:5338-5348.
    • (2007) J Neurosci , vol.27 , pp. 5338-5348
    • Muddashetty, R.S.1    Kelic, S.2    Gross, C.3    Xu, M.4    Bassell, G.J.5
  • 19
    • 0345492360 scopus 로고    scopus 로고
    • The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95
    • Todd PK, Mack KJ, Malter JS. The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proc Natl Acad Sci USA 2003; 100:14374-14378.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14374-14378
    • Todd, P.K.1    Mack, K.J.2    Malter, J.S.3
  • 20
    • 79957578253 scopus 로고    scopus 로고
    • Spatiotemporal expression of PSD-95 in Fmr1 knockout mice brain
    • Zhu ZW, Xu Q, Zhao ZY, Gu WZ, Wu DW. Spatiotemporal expression of PSD-95 in Fmr1 knockout mice brain. Neuropathology 2011; 31:223-229.
    • (2011) Neuropathology , vol.31 , pp. 223-229
    • Zhu, Z.W.1    Xu, Q.2    Zhao, Z.Y.3    Gu, W.Z.4    Wu, D.W.5
  • 21
    • 0000607131 scopus 로고
    • A closed-field intelligence test for rats
    • Rabinovitch MS, Rosvold HE. A closed-field intelligence test for rats. Can J Psychol 1951; 5:122-128.
    • (1951) Can J Psychol , vol.5 , pp. 122-128
    • Rabinovitch, M.S.1    Rosvold, H.E.2
  • 23
    • 7244223228 scopus 로고    scopus 로고
    • Synaptic changes in Alzheimer's disease: Increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence
    • Gylys KH, Fein JA, Yang F, Wiley DJ, Miller CA, Cole GM. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am J Pathol 2004; 165:1809-1817.
    • (2004) Am J Pathol , vol.165 , pp. 1809-1817
    • Gylys, K.H.1    Fein, J.A.2    Yang, F.3    Wiley, D.J.4    Miller, C.A.5    Cole, G.M.6
  • 24
    • 28244433460 scopus 로고    scopus 로고
    • NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder
    • Toro C, Deakin JF. NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder. Schizophr Res 2005; 80:323-330.
    • (2005) Schizophr Res , vol.80 , pp. 323-330
    • Toro, C.1    Deakin, J.F.2
  • 25
    • 79956052512 scopus 로고    scopus 로고
    • Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome
    • Liu ZH, Chuang DM, Smith CB. Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome. Int J Psychopharmacol 2011; 14:618-630.
    • (2011) Int J Psychopharmacol , vol.14 , pp. 618-630
    • Zh, L.1    Chuang, D.M.2    Smith, C.B.3
  • 26
    • 84862637069 scopus 로고    scopus 로고
    • The pathophysiology of fragile X (and what it teaches us about synapses)
    • Bhakar AL, Dolen G, Bear MF. The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci 2012; 35:417-443. Council of Canada
    • (2012) Annu Rev Neurosci , vol.35 , pp. 417-443
    • Bhakar, A.L.1    Dolen, G.2    Bear, M.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.