-
1
-
-
77952311664
-
Oncolytic viruses move forward in clinical trials
-
Rowan K. 2010. Oncolytic viruses move forward in clinical trials. J. Natl. Cancer Inst. 102:590-595. http://dx.doi.org/10.1093/jnci/djq165.
-
(2010)
J. Natl. Cancer Inst.
, vol.102
, pp. 590-595
-
-
Rowan, K.1
-
2
-
-
80052406557
-
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
-
Breitbach CJ, Burke J, Jonker D, Stephenson J, Haas AR, Chow LQ, Nieva J, Hwang TH, Moon A, Patt R, Pelusio A, Le Boeuf F, Burns J, Evgin L, De Silva N, Cvancic S, Robertson T, Je JE, Lee YS, Parato K, Diallo JS, Fenster A, Daneshmand M, Bell JC, Kirn DH. 2011. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature 477:99-102. http://dx.doi.org/10.1038/nature10358.
-
(2011)
Nature
, vol.477
, pp. 99-102
-
-
Breitbach, C.J.1
Burke, J.2
Jonker, D.3
Stephenson, J.4
Haas, A.R.5
Chow, L.Q.6
Nieva, J.7
Hwang, T.H.8
Moon, A.9
Patt, R.10
Pelusio, A.11
Le Boeuf, F.12
Burns, J.13
Evgin, L.14
De Silva, N.15
Cvancic, S.16
Robertson, T.17
Je, J.E.18
Lee, Y.S.19
Parato, K.20
Diallo, J.S.21
Fenster, A.22
Daneshmand, M.23
Bell, J.C.24
Kirn, D.H.25
more..
-
4
-
-
84869217555
-
Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer
-
Hastie E, Grdzelishvili VZ. 2012. Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer. J. Gen. Virol. 93:2529-2545. http://dx.doi.org/10.1099/vir.0.046672-0.
-
(2012)
J. Gen. Virol.
, vol.93
, pp. 2529-2545
-
-
Hastie, E.1
Grdzelishvili, V.Z.2
-
5
-
-
79958166679
-
Oncolytic vesicular stomatitis virus induces apoptosis in U87 glioblastoma cells by a type II death receptor mechanism and induces cell death and tumor clearance in vivo
-
Cary ZD, Willingham MC, Lyles DS. 2011. Oncolytic vesicular stomatitis virus induces apoptosis in U87 glioblastoma cells by a type II death receptor mechanism and induces cell death and tumor clearance in vivo. J. Virol. 85:5708-5717. http://dx.doi.org/10.1128/JVI.02393-10.
-
(2011)
J. Virol.
, vol.85
, pp. 5708-5717
-
-
Cary, Z.D.1
Willingham, M.C.2
Lyles, D.S.3
-
6
-
-
69449099385
-
Vesicular stomatitis virus induces apoptosis primarily through Bak rather than Bax by inactivating Mcl-1 and Bcl-XL
-
Pearce AF, Lyles DS. 2009. Vesicular stomatitis virus induces apoptosis primarily through Bak rather than Bax by inactivating Mcl-1 and Bcl-XL. J. Virol. 83:9102-9112. http://dx.doi.org/10.1128/JVI.00436-09.
-
(2009)
J. Virol.
, vol.83
, pp. 9102-9112
-
-
Pearce, A.F.1
Lyles, D.S.2
-
7
-
-
15244347239
-
Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathways
-
Gaddy DF, Lyles DS. 2005. Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathways. J. Virol. 79: 4170-4179. http://dx.doi.org/10.1128/JVI.79.7.4170-4179.2005.
-
(2005)
J. Virol.
, vol.79
, pp. 4170-4179
-
-
Gaddy, D.F.1
Lyles, D.S.2
-
8
-
-
84878173821
-
Cytosolic sensing of viruses
-
Goubau D, Deddouche S, Reis ESC. 2013. Cytosolic sensing of viruses. Immunity 38:855-869. http://dx.doi.org/10.1016/j.immuni.2013.05.007.
-
(2013)
Immunity
, vol.38
, pp. 855-869
-
-
Goubau, D.1
Deddouche, S.2
Reis, E.S.C.3
-
9
-
-
0036224352
-
Viral oncolysis
-
Mullen JT, Tanabe KK. 2002. Viral oncolysis. Oncologist 7:106-119. http://dx.doi.org/10.1634/theoncologist.7-2-106.
-
(2002)
Oncologist
, vol.7
, pp. 106-119
-
-
Mullen, J.T.1
Tanabe, K.K.2
-
10
-
-
33947245441
-
History of oncolytic viruses: genesis to genetic engineering
-
Kelly E, Russell SJ. 2007. History of oncolytic viruses: genesis to genetic engineering. Mol. Ther. 15:651-659. http://dx.doi.org/10.1038/sj.mt.6300108.
-
(2007)
Mol. Ther.
, vol.15
, pp. 651-659
-
-
Kelly, E.1
Russell, S.J.2
-
11
-
-
59849122602
-
Natural and genetically engineered viral agents for oncolysis and gene therapy of human cancers
-
Sinkovics JG, Horvath JC. 2008. Natural and genetically engineered viral agents for oncolysis and gene therapy of human cancers. Arch. Immunol. Ther. Exp. (Warsz) 56(Suppl 1):3s-59s. http://dx.doi.org/10.1007/s00005-008-0047-9.
-
(2008)
Arch. Immunol. Ther. Exp. (Warsz)
, vol.56
, Issue.SUPPL. 1
-
-
Sinkovics, J.G.1
Horvath, J.C.2
-
12
-
-
84933524463
-
Preclinical safety and activity of recombinant VSV-IFN-beta in an immunocompetent model of squamous cell carcinoma of the head and neck
-
Kurisetty VV, Heiber J, Myers R, Pereira GS, Goodwin JW, Federspiel MJ, Russell SJ, Peng KW, Barber G, Merchan JR. 2013. Preclinical safety and activity of recombinant VSV-IFN-beta in an immunocompetent model of squamous cell carcinoma of the head and neck. Head Neck. http://dx.doi.org/10.1002/hed.23502.
-
(2013)
Head Neck
-
-
Kurisetty, V.V.1
Heiber, J.2
Myers, R.3
Pereira, G.S.4
Goodwin, J.W.5
Federspiel, M.J.6
Russell, S.J.7
Peng, K.W.8
Barber, G.9
Merchan, J.R.10
-
13
-
-
84863722111
-
Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-beta
-
Naik S, Nace R, Barber GN, Russell SJ. 2012. Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-beta. Cancer Gene Ther. 19:443-450. http://dx.doi.org/10 .1038/cgt.2012.14.
-
(2012)
Cancer Gene Ther.
, vol.19
, pp. 443-450
-
-
Naik, S.1
Nace, R.2
Barber, G.N.3
Russell, S.J.4
-
14
-
-
10744223476
-
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents
-
Stojdl DF, Lichty BD, ten Oever BR, Paterson JM, Power AT, Knowles S, Marius R, Reynard J, Poliquin L, Atkins H, Brown EG, Durbin RK, Durbin JE, Hiscott J, Bell JC. 2003. VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents. Cancer Cell 4:263-275. http://dx.doi.org/10.1016/S1535-6108(03)00241-1.
-
(2003)
Cancer Cell
, vol.4
, pp. 263-275
-
-
Stojdl, D.F.1
Lichty, B.D.2
ten Oever, B.R.3
Paterson, J.M.4
Power, A.T.5
Knowles, S.6
Marius, R.7
Reynard, J.8
Poliquin, L.9
Atkins, H.10
Brown, E.G.11
Durbin, R.K.12
Durbin, J.E.13
Hiscott, J.14
Bell, J.C.15
-
15
-
-
0033929057
-
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
-
Stojdl DF, Lichty B, Knowles S, Marius R, Atkins H, Sonenberg N, Bell JC. 2000. Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus. Nat. Med. 6:821-825. http://dx.doi .org/10.1038/77558.
-
(2000)
Nat. Med.
, vol.6
, pp. 821-825
-
-
Stojdl, D.F.1
Lichty, B.2
Knowles, S.3
Marius, R.4
Atkins, H.5
Sonenberg, N.6
Bell, J.C.7
-
16
-
-
11344285489
-
VSV disrupts the Rae1/ mrnp41 mRNA nuclear export pathway
-
Faria PA, Chakraborty P, Levay A, Barber GN, Ezelle HJ, Enninga J, Arana C, van Deursen J, Fontoura BM. 2005. VSV disrupts the Rae1/ mrnp41 mRNA nuclear export pathway. Mol. Cell 17:93-102. http://dx .doi.org/10.1016/j.molcel.2004.11.023.
-
(2005)
Mol. Cell
, vol.17
, pp. 93-102
-
-
Faria, P.A.1
Chakraborty, P.2
Levay, A.3
Barber, G.N.4
Ezelle, H.J.5
Enninga, J.6
Arana, C.7
van Deursen, J.8
Fontoura, B.M.9
-
17
-
-
27944432605
-
VSV-tumor selective replication and protein translation
-
Barber GN. 2005. VSV-tumor selective replication and protein translation. Oncogene 24:7710-7719. http://dx.doi.org/10.1038/sj.onc.1209042.
-
(2005)
Oncogene
, vol.24
, pp. 7710-7719
-
-
Barber, G.N.1
-
18
-
-
34347331167
-
Viruses as anticancer drugs
-
Russell SJ, Peng KW. 2007. Viruses as anticancer drugs. Trends Pharmacol. Sci. 28:326-333. http://dx.doi.org/10.1016/j.tips.2007.05.005.
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, pp. 326-333
-
-
Russell, S.J.1
Peng, K.W.2
-
19
-
-
54449089024
-
Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis
-
Nguyen TL, Abdelbary H, Arguello M, Breitbach C, Leveille S, Diallo JS, Yasmeen A, Bismar TA, Kirn D, Falls T, Snoulten VE, Vanderhyden BC, Werier J, Atkins H, Vähä-Koskela MJ, Stojdl DF, Bell JC, Hiscott J. 2008. Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis. Proc. Natl. Acad. Sci. U. S. A. 105:14981-14986. http://dx.doi.org/10 .1073/pnas.0803988105.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 14981-14986
-
-
Nguyen, T.L.1
Abdelbary, H.2
Arguello, M.3
Breitbach, C.4
Leveille, S.5
Diallo, J.S.6
Yasmeen, A.7
Bismar, T.A.8
Kirn, D.9
Falls, T.10
Snoulten, V.E.11
Vanderhyden, B.C.12
Werier, J.13
Atkins, H.14
Vähä-Koskela, M.J.15
Stojdl, D.F.16
Bell, J.C.17
Hiscott, J.18
-
20
-
-
7444243792
-
Sensitivity of prostate tumors to wild type and M protein mutant vesicular stomatitis viruses
-
Ahmed M, Cramer SD, Lyles DS. 2004. Sensitivity of prostate tumors to wild type and M protein mutant vesicular stomatitis viruses. Virology 330:34-49. http://dx.doi.org/10.1016/j.virol.2004.08.039.
-
(2004)
Virology
, vol.330
, pp. 34-49
-
-
Ahmed, M.1
Cramer, S.D.2
Lyles, D.S.3
-
21
-
-
77953544825
-
Oncolytic viruses and histone deacetylase inhibitors-a multi-pronged strategy to target tumor cells
-
Nguyen TL, Wilson MG, Hiscott J. 2010. Oncolytic viruses and histone deacetylase inhibitors-a multi-pronged strategy to target tumor cells. Cytokine Growth Factor Rev. 21:153-159. http://dx.doi.org/10.1016/j .cytogfr.2010.03.002.
-
(2010)
Cytokine Growth Factor Rev.
, vol.21
, pp. 153-159
-
-
Nguyen, T.L.1
Wilson, M.G.2
Hiscott, J.3
-
22
-
-
34547897023
-
Histone deacetylases and cancer
-
Glozak MA, Seto E. 2007. Histone deacetylases and cancer. Oncogene 26:5420-5432. http://dx.doi.org/10.1038/sj.onc.1210610.
-
(2007)
Oncogene
, vol.26
, pp. 5420-5432
-
-
Glozak, M.A.1
Seto, E.2
-
23
-
-
60149097656
-
The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells
-
Katsura T, Iwai S, Ota Y, Shimizu H, Ikuta K, Yura Y. 2009. The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells. Cancer Gene Ther. 16:237-245. http://dx .doi.org/10.1038/cgt.2008.81.
-
(2009)
Cancer Gene Ther.
, vol.16
, pp. 237-245
-
-
Katsura, T.1
Iwai, S.2
Ota, Y.3
Shimizu, H.4
Ikuta, K.5
Yura, Y.6
-
24
-
-
2542523228
-
Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors
-
Pei XY, Dai Y, Grant S. 2004. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors. Clin. Cancer Res. 10: 3839-3852. http://dx.doi.org/10.1158/1078-0432.CCR-03-0561.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3839-3852
-
-
Pei, X.Y.1
Dai, Y.2
Grant, S.3
-
25
-
-
84855464229
-
HDACi: molecular mechanisms and therapeutic implications in the innate immune system
-
Suliman BA, Xu D, Williams BR. 2012. HDACi: molecular mechanisms and therapeutic implications in the innate immune system. Immunol. Cell Biol. 90:23-32. http://dx.doi.org/10.1038/icb.2011.92.
-
(2012)
Immunol. Cell Biol.
, vol.90
, pp. 23-32
-
-
Suliman, B.A.1
Xu, D.2
Williams, B.R.3
-
26
-
-
84874634756
-
Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells
-
Laurenzana A, Balliu M, Cellai C, Romanelli MN, Paoletti F. 2013. Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells. PLoS One 8:e58267. http://dx.doi.org/10.1371/journal.pone.0058267.
-
(2013)
PLoS One
, vol.8
-
-
Laurenzana, A.1
Balliu, M.2
Cellai, C.3
Romanelli, M.N.4
Paoletti, F.5
-
27
-
-
84860381721
-
A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL
-
Hwang JJ, Kim YS, Kim T, Kim MJ, Jeong IG, Lee JH, Choi J, Jang S, Ro S, Kim CS. 2012. A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL. Invest. New Drugs 30:1434-1442. http://dx.doi.org/10 .1007/s10637-011-9718-1.
-
(2012)
Invest. New Drugs
, vol.30
, pp. 1434-1442
-
-
Hwang, J.J.1
Kim, Y.S.2
Kim, T.3
Kim, M.J.4
Jeong, I.G.5
Lee, J.H.6
Choi, J.7
Jang, S.8
Ro, S.9
Kim, C.S.10
-
28
-
-
58149234400
-
A multiple-loop, double-cube microarray design applied to prostate cancer cell lines with variable sensitivity to histone deacetylase inhibitors
-
Kortenhorst MS, Zahurak M, Shabbeer S, Kachhap S, Galloway N, Parmigiani G, Verheul HM, Carducci MA. 2008. A multiple-loop, double-cube microarray design applied to prostate cancer cell lines with variable sensitivity to histone deacetylase inhibitors. Clin. Cancer Res. 14: 6886-6894. http://dx.doi.org/10.1158/1078-0432.CCR-08-0119.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 6886-6894
-
-
Kortenhorst, M.S.1
Zahurak, M.2
Shabbeer, S.3
Kachhap, S.4
Galloway, N.5
Parmigiani, G.6
Verheul, H.M.7
Carducci, M.A.8
-
29
-
-
33750288048
-
Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor
-
Xu W, Ngo L, Perez G, Dokmanovic M, Marks PA. 2006. Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor. Proc. Natl. Acad. Sci. U. S. A. 103:15540-15545. http://dx.doi.org/10.1073/pnas.0607518103.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 15540-15545
-
-
Xu, W.1
Ngo, L.2
Perez, G.3
Dokmanovic, M.4
Marks, P.A.5
-
30
-
-
84860135029
-
Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death
-
Gammoh N, Lam D, Puente C, Ganley I, Marks PA, Jiang X. 2012. Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death. Proc. Natl. Acad. Sci. U. S. A. 109:6561-6565. http://dx.doi.org/10.1073/pnas.1204429109.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 6561-6565
-
-
Gammoh, N.1
Lam, D.2
Puente, C.3
Ganley, I.4
Marks, P.A.5
Jiang, X.6
-
31
-
-
84869005194
-
Molecular mechanism of SAHA on regulation of autophagic cell death in tamoxifen-resistant MCF-7 breast cancer cells
-
Lee YJ, Won AJ, Lee J, Jung JH, Yoon S, Lee BM, Kim HS. 2012. Molecular mechanism of SAHA on regulation of autophagic cell death in tamoxifen-resistant MCF-7 breast cancer cells. Int. J. Med. Sci. 9:881-893. http://dx.doi.org/10.7150/ijms.5011.
-
(2012)
Int. J. Med. Sci.
, vol.9
, pp. 881-893
-
-
Lee, Y.J.1
Won, A.J.2
Lee, J.3
Jung, J.H.4
Yoon, S.5
Lee, B.M.6
Kim, H.S.7
-
32
-
-
84873660610
-
Autophagy inhumanhealth and disease
-
ChoiAM,RyterSW,Levine B. 2013. Autophagy inhumanhealth and disease. N. Engl. J. Med. 368:651-662. http://dx.doi.org/10.1056/NEJMra1205406.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
33
-
-
75649122282
-
Subversion of the cellular autophagy pathway by viruses
-
Kirkegaard K. 2009. Subversion of the cellular autophagy pathway by viruses. Curr. Top. Microbiol. Immunol. 335:323-333. http://dx.doi.org/10.1007/978-3-642-00302-8_16.
-
(2009)
Curr. Top. Microbiol. Immunol.
, vol.335
, pp. 323-333
-
-
Kirkegaard, K.1
-
34
-
-
70449360945
-
Viruses and autophagy
-
Kudchodkar SB, Levine B. 2009. Viruses and autophagy. Rev. Med. Virol. 19:359-378. http://dx.doi.org/10.1002/rmv.630.
-
(2009)
Rev. Med. Virol.
, vol.19
, pp. 359-378
-
-
Kudchodkar, S.B.1
Levine, B.2
-
35
-
-
77953597957
-
Viruses and the autophagy machinery
-
Dreux M, Chisari FV. 2010. Viruses and the autophagy machinery. Cell Cycle 9:1295-1307. http://dx.doi.org/10.4161/cc.9.7.11109.
-
(2010)
Cell Cycle
, vol.9
, pp. 1295-1307
-
-
Dreux, M.1
Chisari, F.V.2
-
36
-
-
84877918290
-
Targeting autophagy to enhance oncolytic virus-based cancer therapy
-
Meng S, Xu J, Wu Y, Ding C. 2013. Targeting autophagy to enhance oncolytic virus-based cancer therapy. Exp. Opin. Biol. Ther. 13:863-873. http://dx.doi.org/10.1517/14712598.2013.774365.
-
(2013)
Exp. Opin. Biol. Ther.
, vol.13
, pp. 863-873
-
-
Meng, S.1
Xu, J.2
Wu, Y.3
Ding, C.4
-
37
-
-
84856349942
-
p65-Dependent productionof interleukin-1betabyosteolytic prostatecancercellscausesaninduction of chemokine expression in osteoblasts
-
Schulze J, Weber K, Baranowsky A, Streichert T, Lange T, Spiro AS, Albers J, Seitz S, Zustin J, Amling M, Fehse B, Schinke T. 2012. p65-Dependent productionof interleukin-1betabyosteolytic prostatecancercellscausesaninduction of chemokine expression in osteoblasts. Cancer Lett. 317:106-113. http://dx.doi .org/10.1016/j.canlet.2011.11.016.
-
(2012)
Cancer Lett.
, vol.317
, pp. 106-113
-
-
Schulze, J.1
Weber, K.2
Baranowsky, A.3
Streichert, T.4
Lange, T.5
Spiro, A.S.6
Albers, J.7
Seitz, S.8
Zustin, J.9
Amling, M.10
Fehse, B.11
Schinke, T.12
-
38
-
-
84865119303
-
Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex
-
Belgnaoui SM, Paz S, Samuel S, Goulet ML, Sun Q, Kikkert M, Iwai K, Dikic I, Hiscott J, Lin R. 2012. Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex. Cell Host Microbe 12:211-222. http://dx.doi.org/10.1016/j.chom.2012.06.009.
-
(2012)
Cell Host Microbe
, vol.12
, pp. 211-222
-
-
Belgnaoui, S.M.1
Paz, S.2
Samuel, S.3
Goulet, M.L.4
Sun, Q.5
Kikkert, M.6
Iwai, K.7
Dikic, I.8
Hiscott, J.9
Lin, R.10
-
39
-
-
33847234661
-
Lookup peaks: a hybrid of de novo sequencing and database search for protein identification by tandem mass spectrometry
-
BernM,Cai Y, Goldberg D. 2007. Lookup peaks: a hybrid of de novo sequencing and database search for protein identification by tandem mass spectrometry. Anal. Chem. 79:1393-1400. http://dx.doi.org/10.1021/ac0617013.
-
(2007)
Anal. Chem.
, vol.79
, pp. 1393-1400
-
-
Bern, M.1
Cai, Y.2
Goldberg, D.3
-
40
-
-
77955458622
-
Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance
-
Burgess A, Vigneron S, Brioudes E, Labbe JC, Lorca T, Castro A. 2010. Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance. Proc. Natl. Acad. Sci. U. S. A. 107: 12564-12569. http://dx.doi.org/10.1073/pnas.0914191107.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 12564-12569
-
-
Burgess, A.1
Vigneron, S.2
Brioudes, E.3
Labbe, J.C.4
Lorca, T.5
Castro, A.6
-
41
-
-
84869869682
-
HDAC inhibitor-based therapies: can we interpret the code? Mol
-
New M, Olzscha H, La Thangue NB. 2012. HDAC inhibitor-based therapies: can we interpret the code? Mol. Oncol. 6:637-656. http://dx.doi .org/10.1016/j.molonc.2012.09.003.
-
(2012)
Oncol.
, vol.6
, pp. 637-656
-
-
New, M.1
Olzscha, H.2
La Thangue, N.B.3
-
42
-
-
2942752412
-
Regulation of NF-kappaB action by reversible acetylation
-
Greene WC, Chen LF. 2004. Regulation of NF-kappaB action by reversible acetylation. Novartis Found. Symp. 259:208-225. http://dx.doi.org/10.1002/0470862637.ch15.
-
(2004)
Novartis Found. Symp.
, vol.259
, pp. 208-225
-
-
Greene, W.C.1
Chen, L.F.2
-
43
-
-
0037011056
-
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
-
Chen LF, Mu Y, Greene WC. 2002. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J. 21:6539-6548. http://dx.doi.org/10.1093/emboj/cdf660.
-
(2002)
EMBO J.
, vol.21
, pp. 6539-6548
-
-
Chen, L.F.1
Mu, Y.2
Greene, W.C.3
-
44
-
-
84863690805
-
BAY 11-7082 is a broad-spectrum inhibitor with anti-inflammatory activity against multiple targets
-
Lee J, Rhee MH, Kim E, Cho JY. 2012. BAY 11-7082 is a broad-spectrum inhibitor with anti-inflammatory activity against multiple targets. Mediators Inflamm. 2012:416036. http://dx.doi.org/10.1155/2012/416036.
-
(2012)
Mediators Inflamm.
, vol.2012
, pp. 416036
-
-
Lee, J.1
Rhee, M.H.2
Kim, E.3
Cho, J.Y.4
-
45
-
-
78049480691
-
GeneCards Version 3: the human gene integrator
-
baq020
-
Safran M, Dalah I, Alexander J, Rosen N, Iny Stein T, Shmoish M, Nativ N, Bahir I, Doniger T, Krug H, Sirota-Madi A, Olender T, Golan Y, Stelzer G, Harel A, Lancet D. 2010. GeneCards Version 3: the human gene integrator. Database 2010:baq020. http://dx.doi.org/10.1093/database/baq020.
-
(2010)
Database
, vol.2010
-
-
Safran, M.1
Dalah, I.2
Alexander, J.3
Rosen, N.4
Iny Stein, T.5
Shmoish, M.6
Nativ, N.7
Bahir, I.8
Doniger, T.9
Krug, H.10
Sirota-Madi, A.11
Olender, T.12
Golan, Y.13
Stelzer, G.14
Harel, A.15
Lancet, D.16
-
46
-
-
84866560614
-
A novel image-based cytometry method for autophagy detection in living cells
-
Chan LL, Shen D, Wilkinson AR, Patton W, Lai N, Chan E, Kuksin D, Lin B, Qiu J. 2012. A novel image-based cytometry method for autophagy detection in living cells. Autophagy 8:1371-1382. http://dx.doi.org/10 .4161/auto.21028.
-
(2012)
Autophagy
, vol.8
, pp. 1371-1382
-
-
Chan, L.L.1
Shen, D.2
Wilkinson, A.R.3
Patton, W.4
Lai, N.5
Chan, E.6
Kuksin, D.7
Lin, B.8
Qiu, J.9
-
47
-
-
84873733623
-
Autophagy in antiviral innate immunity
-
Richetta C, Faure M. 2013. Autophagy in antiviral innate immunity. Cell Microbiol. 15:368-376. http://dx.doi.org/10.1111/cmi.12043.
-
(2013)
Cell Microbiol.
, vol.15
, pp. 368-376
-
-
Richetta, C.1
Faure, M.2
-
48
-
-
80655124407
-
A comprehensive glossary of autophagyrelated molecules and processes (2nd edition)
-
Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Fin-Beiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, Levine B, Melia TJ, Mizushima N, Rubinsztein DC, Simonsen A, Thorburn A, Thumm M, Tooze SA. 2011. A comprehensive glossary of autophagyrelated molecules and processes (2nd edition). Autophagy 7:1273-1294. http://dx.doi.org/10.4161/auto.7.11.17661.
-
(2011)
Autophagy
, vol.7
, pp. 1273-1294
-
-
Klionsky, D.J.1
Baehrecke, E.H.2
Brumell, J.H.3
Chu, C.T.4
Codogno, P.5
Cuervo, A.M.6
Cuervo, A.M.7
Debnath, J.8
Deretic, V.9
Elazar, Z.10
Eskelinen, E.L.11
Fin-Beiner, S.12
Fueyo-Margareto, J.13
Gewirtz, D.14
Jäättelä, M.15
Kroemer, G.16
Levine, B.17
Melia, T.J.18
Mizushima, N.19
Rubinsztein, D.C.20
Simonsen, A.21
Thorburn, A.22
Thumm, M.23
Tooze, S.A.24
more..
-
49
-
-
84861406715
-
The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon
-
Alvarez-Breckenridge CA, Yu J, Price R, Wei M, Wang Y, Nowicki MO, Ha YP, Bergin S, Hwang C, Fernandez SA, Kaur B, Caligiuri MA, Chiocca EA. 2012. The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon. J. Virol. 86:4566-4577. http://dx.doi.org/10.1128/JVI.05545-11.
-
(2012)
J. Virol.
, vol.86
, pp. 4566-4577
-
-
Alvarez-Breckenridge, C.A.1
Yu, J.2
Price, R.3
Wei, M.4
Wang, Y.5
Nowicki, M.O.6
Ha, Y.P.7
Bergin, S.8
Hwang, C.9
Fernandez, S.A.10
Kaur, B.11
Caligiuri, M.A.12
Chiocca, E.A.13
-
50
-
-
78651234760
-
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors
-
MacTavish H, Diallo JS, Huang B, Stanford M, Le Boeuf F, De Silva N, Cox J, Simmons JG, Guimond T, Falls T, McCart JA, Atkins H, Breitbach C, Kirn D, Thorne S, Bell JC. 2010. Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors. PLoS One 5:e14462. http://dx.doi.org/10.1371/journal.pone.0014462.
-
(2010)
PLoS One
, vol.5
-
-
MacTavish, H.1
Diallo, J.S.2
Huang, B.3
Stanford, M.4
Le Boeuf, F.5
De Silva, N.6
Cox, J.7
Simmons, J.G.8
Guimond, T.9
Falls, T.10
McCart, J.A.11
Atkins, H.12
Breitbach, C.13
Kirn, D.14
Thorne, S.15
Bell, J.C.16
-
51
-
-
29144485434
-
Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells
-
Watanabe T, Hioki M, Fujiwara T, Nishizaki M, Kagawa S, Taki M, Kishimoto H, Endo Y, Urata Y, Tanaka N, Fujiwara T. 2006. Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells. Exp. Cell Res. 312:256-265. http://dx.doi.org/10.1016/j .yexcr.2005.10.026.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 256-265
-
-
Watanabe, T.1
Hioki, M.2
Fujiwara, T.3
Nishizaki, M.4
Kagawa, S.5
Taki, M.6
Kishimoto, H.7
Endo, Y.8
Urata, Y.9
Tanaka, N.10
Fujiwara, T.11
-
52
-
-
41149136753
-
Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65
-
Buerki C, Rothgiesser KM, Valovka T, Owen HR, Rehrauer H, Fey M, Lane WS, Hottiger MO. 2008. Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res. 36:1665-1680. http://dx.doi.org/10.1093/nar/gkn003.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 1665-1680
-
-
Buerki, C.1
Rothgiesser, K.M.2
Valovka, T.3
Owen, H.R.4
Rehrauer, H.5
Fey, M.6
Lane, W.S.7
Hottiger, M.O.8
-
53
-
-
0037462725
-
Post-activation turn-off of NFkappa B-dependent transcription is regulated by acetylation of p65
-
Kiernan R, Bres V, Ng RW, Coudart MP, El Messaoudi S, Sardet C, Jin DY, Emiliani S, Benkirane M. 2003. Post-activation turn-off of NFkappa B-dependent transcription is regulated by acetylation of p65. J. Biol. Chem. 278:2758-2766. http://dx.doi.org/10.1074/jbc.M209572200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2758-2766
-
-
Kiernan, R.1
Bres, V.2
Ng, R.W.3
Coudart, M.P.4
El Messaoudi, S.5
Sardet, C.6
Jin, D.Y.7
Emiliani, S.8
Benkirane, M.9
-
54
-
-
39849083763
-
Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death
-
Alonso MM, Jiang H, Yokoyama T, Xu J, Bekele NB, Lang FF, Kondo S, Gomez-Manzano C, Fueyo J. 2008. Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death. Mol. Ther. 16:487-493. http://dx.doi.org/10.1038/sj.mt.6300400.
-
(2008)
Mol. Ther.
, vol.16
, pp. 487-493
-
-
Alonso, M.M.1
Jiang, H.2
Yokoyama, T.3
Xu, J.4
Bekele, N.B.5
Lang, F.F.6
Kondo, S.7
Gomez-Manzano, C.8
Fueyo, J.9
-
55
-
-
84879689538
-
BCL-2 inhibitors sensitize therapy-resistant chronic lymphocytic leukemia cells to VSV oncolysis
-
Samuel S, Beljanski V, Van Grevenynghe J, Richards S, Ben Yebdri F, He Z, Nichols C, Belgnaoui SM, Steel C, Goulet ML, Shamy A, Brown D, Abesada G, Haddad EK, Hiscott J. 2013. BCL-2 inhibitors sensitize therapy-resistant chronic lymphocytic leukemia cells to VSV oncolysis. Mol. Ther. 21:1413-1423. http://dx.doi.org/10.1038/mt.2013.91.
-
(2013)
Mol. Ther.
, vol.21
, pp. 1413-1423
-
-
Samuel, S.1
Beljanski, V.2
Van Grevenynghe, J.3
Richards, S.4
Ben Yebdri, F.5
He, Z.6
Nichols, C.7
Belgnaoui, S.M.8
Steel, C.9
Goulet, M.L.10
Shamy, A.11
Brown, D.12
Abesada, G.13
Haddad, E.K.14
Hiscott, J.15
-
56
-
-
84857305639
-
Direct molecular interactions between Beclin 1 and the canonical NFkappaB activation pathway
-
Niso-Santano M, Criollo A, Malik SA, Michaud M, Morselli E, Marino G, Lachkar S, Galluzzi L, Maiuri MC, Kroemer G. 2012. Direct molecular interactions between Beclin 1 and the canonical NFkappaB activation pathway. Autophagy 8:268-270. http://dx.doi.org/10.4161/auto.8.2.18845.
-
(2012)
Autophagy
, vol.8
, pp. 268-270
-
-
Niso-Santano, M.1
Criollo, A.2
Malik, S.A.3
Michaud, M.4
Morselli, E.5
Marino, G.6
Lachkar, S.7
Galluzzi, L.8
Maiuri, M.C.9
Kroemer, G.10
-
57
-
-
33750433585
-
Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses
-
Hiscott J, Nguyen TL, Arguello M, Nakhaei P, Paz S. 2006. Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses. Oncogene 25:6844-6867. http://dx.doi.org/10.1038/sj .onc.1209941.
-
(2006)
Oncogene
, vol.25
, pp. 6844-6867
-
-
Hiscott, J.1
Nguyen, T.L.2
Arguello, M.3
Nakhaei, P.4
Paz, S.5
-
58
-
-
79251512287
-
Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes
-
Shrivastava S, Raychoudhuri A, Steele R, Ray R, Ray RB. 2011. Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes. Hepatology 53:406-414. http://dx.doi.org/10 .1002/hep.24073.
-
(2011)
Hepatology
, vol.53
, pp. 406-414
-
-
Shrivastava, S.1
Raychoudhuri, A.2
Steele, R.3
Ray, R.4
Ray, R.B.5
-
59
-
-
35348921764
-
The Atg5 Atg12 conjugate associates with innate antiviral immune responses
-
Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, Okuda K. 2007. The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proc. Natl. Acad. Sci. U. S. A. 104:14050-14055. http://dx.doi.org/10.1073/pnas .0704014104.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 14050-14055
-
-
Jounai, N.1
Takeshita, F.2
Kobiyama, K.3
Sawano, A.4
Miyawaki, A.5
Xin, K.Q.6
Ishii, K.J.7
Kawai, T.8
Akira, S.9
Suzuki, K.10
Okuda, K.11
-
60
-
-
84875182214
-
Oncolytic virus therapy for cancer: the first wave of translational clinical trials
-
Patel MR, Kratzke RA. 2013. Oncolytic virus therapy for cancer: the first wave of translational clinical trials. Transl. Res. 161:355-364. http://dx.doi .org/10.1016/j.trsl.2012.12.010.
-
(2013)
Transl. Res.
, vol.161
, pp. 355-364
-
-
Patel, M.R.1
Kratzke, R.A.2
|