메뉴 건너뛰기




Volumn 49, Issue 2, 2014, Pages 165-172

New insights into the molecular pathogenesis of intrahepatic cholangiocarcinoma

Author keywords

Biliary tract cancers; Cholangiocytes; Liver cancers

Indexed keywords

CETUXIMAB; CISPLATIN; ERLOTINIB; GEMCITABINE; OXALIPLATIN; SELUMETINIB; SORAFENIB; SUNITINIB; TRANSCRIPTOME;

EID: 84896723581     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-013-0894-y     Document Type: Review
Times cited : (49)

References (57)
  • 1
    • 79953705666 scopus 로고    scopus 로고
    • Cholangiocarcinoma - Controversies and challenges
    • 1:CAS:528:DC%2BC3MXktFKntrs%3D 3888819 21460876 10.1038/nrgastro.2011.20
    • Patel T. Cholangiocarcinoma - controversies and challenges. Nat Rev Gastroenterol Hepatol. 2011;8(4):189-200.
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , Issue.4 , pp. 189-200
    • Patel, T.1
  • 2
    • 77649180424 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Update and future perspectives
    • 1:CAS:528:DC%2BC3cXmtVSitLs%3D 20097142 10.1016/j.dld.2009.12.008
    • Gatto M, Bragazzi MC, Semeraro R, Napoli C, Gentile R, Torrice A, et al. Cholangiocarcinoma: update and future perspectives. Dig Liver Dis. 2010;42(4):253-60.
    • (2010) Dig Liver Dis , vol.42 , Issue.4 , pp. 253-260
    • Gatto, M.1    Bragazzi, M.C.2    Semeraro, R.3    Napoli, C.4    Gentile, R.5    Torrice, A.6
  • 3
    • 3042789089 scopus 로고    scopus 로고
    • Worldwide trends in mortality from biliary tract malignancies
    • (Epub 2002/05/07)
    • Patel T. Worldwide trends in mortality from biliary tract malignancies. BMC Cancer. 2002;2:10 (Epub 2002/05/07).
    • (2002) BMC Cancer , vol.2 , pp. 10
    • Patel, T.1
  • 4
    • 80051716955 scopus 로고    scopus 로고
    • Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany
    • 10.3109/00365521.2011.589472 (Epub 2011/06/23)
    • von Hahn T, Ciesek S, Wegener G, Plentz RR, Weismuller TJ, Wedemeyer H, et al. Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany. Scand J Gastroenterol. 2011;46(9):1092-8 (Epub 2011/06/23).
    • (2011) Scand J Gastroenterol , vol.46 , Issue.9 , pp. 1092-1098
    • Von Hahn, T.1    Ciesek, S.2    Wegener, G.3    Plentz, R.R.4    Weismuller, T.J.5    Wedemeyer, H.6
  • 5
    • 0034982536 scopus 로고    scopus 로고
    • Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States
    • 1:STN:280:DC%2BD3MzhvFajsw%3D%3D 11391522 10.1053/jhep.2001.25087 (Epub 2001/06/08)
    • Patel T. Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States. Hepatology. 2001;33(6):1353-7 (Epub 2001/06/08).
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1353-1357
    • Patel, T.1
  • 6
    • 77957739345 scopus 로고    scopus 로고
    • Cholangiocarcinoma: New insights into disease pathogenesis and biology
    • 2954129 20937455 10.1016/j.idc.2010.07.006 (Epub 2010/10/13)
    • Braconi C, Patel T. Cholangiocarcinoma: new insights into disease pathogenesis and biology. Infect Dis Clin North Am. 2010;24(4):871-884, vii (Epub 2010/10/13).
    • (2010) Infect Dis Clin North Am , vol.24 , Issue.4 , pp. 871-884
    • Braconi, C.1    Patel, T.2
  • 7
    • 67650742500 scopus 로고    scopus 로고
    • Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract
    • (Epub 2009/05/14)
    • Miller G, Socci ND, Dhall D, D'Angelica M, DeMatteo RP, Allen PJ, et al. Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract. J Exp Clin Cancer Res CR. 2009;28:62 (Epub 2009/05/14).
    • (2009) J Exp Clin Cancer Res CR , vol.28 , pp. 62
    • Miller, G.1    Socci, N.D.2    Dhall, D.3    D'Angelica, M.4    Dematteo, R.P.5    Allen, P.J.6
  • 8
    • 34247854758 scopus 로고    scopus 로고
    • Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: A hospital-based case-control study
    • 17324130 10.1111/j.1572-0241.2007.01104.x (Epub 2007/02/28)
    • Shaib YH, El-Serag HB, Nooka AK, Thomas M, Brown TD, Patt YZ, et al. Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a hospital-based case-control study. Am J Gastroenterol. 2007;102(5):1016-21 (Epub 2007/02/28).
    • (2007) Am J Gastroenterol , vol.102 , Issue.5 , pp. 1016-1021
    • Shaib, Y.H.1    El-Serag, H.B.2    Nooka, A.K.3    Thomas, M.4    Brown, T.D.5    Patt, Y.Z.6
  • 9
    • 79955974642 scopus 로고    scopus 로고
    • Comparison of incidence of intrahepatic and extrahepatic cholangiocarcinoma - Focus on East and South-Eastern Asia
    • (Epub 2011/01/05)
    • Shin HR, Oh JK, Masuyer E, Curado MP, Bouvard V, Fang Y, et al. Comparison of incidence of intrahepatic and extrahepatic cholangiocarcinoma - focus on East and South-Eastern Asia. Asian Pac J Cancer Prev APJCP. 2010;11(5):1159-66 (Epub 2011/01/05).
    • (2010) Asian Pac J Cancer Prev APJCP , vol.11 , Issue.5 , pp. 1159-1166
    • Shin, H.R.1    Oh, J.K.2    Masuyer, E.3    Curado, M.P.4    Bouvard, V.5    Fang, Y.6
  • 10
    • 84896719290 scopus 로고    scopus 로고
    • Classification, Diagnosis, and Management of Cholangiocarcinoma
    • (Epub 2012/09/18)
    • Razumilava N, Gores GJ. Classification, Diagnosis, and Management of Cholangiocarcinoma. Clin Gastroenterol Hepatol. 2012 (Epub 2012/09/18).
    • (2012) Clin Gastroenterol Hepatol
    • Razumilava, N.1    Gores, G.J.2
  • 11
    • 80052552459 scopus 로고    scopus 로고
    • Clinical diagnosis and staging of cholangiocarcinoma
    • 3331791 21808282 10.1038/nrgastro.2011.131 (Epub 2011/08/03)
    • Blechacz B, Komuta M, Roskams T, Gores GJ. Clinical diagnosis and staging of cholangiocarcinoma. Nat Rev Gastroenterol Hepatol. 2011;8(9):512-22 (Epub 2011/08/03).
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , Issue.9 , pp. 512-522
    • Blechacz, B.1    Komuta, M.2    Roskams, T.3    Gores, G.J.4
  • 12
    • 0242522356 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma: Macroscopic type and stage classification
    • 10.1007/s00534-002-0732-8 (Epub 2003/11/05)
    • Yamasaki S. Intrahepatic cholangiocarcinoma: macroscopic type and stage classification. J Hepato Biliary Pancreat Surg. 2003;10(4):288-91 (Epub 2003/11/05).
    • (2003) J Hepato Biliary Pancreat Surg , vol.10 , Issue.4 , pp. 288-291
    • Yamasaki, S.1
  • 13
    • 79951902341 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma: New insights in pathology
    • 21344350 10.1055/s-0031-1272839 (Epub 2011/02/24)
    • Sempoux C, Jibara G, Ward SC, Fan C, Qin L, Roayaie S, et al. Intrahepatic cholangiocarcinoma: new insights in pathology. Semin Liver Dis. 2011;31(1):49-60 (Epub 2011/02/24).
    • (2011) Semin Liver Dis , vol.31 , Issue.1 , pp. 49-60
    • Sempoux, C.1    Jibara, G.2    Ward, S.C.3    Fan, C.4    Qin, L.5    Roayaie, S.6
  • 14
    • 79960001615 scopus 로고    scopus 로고
    • Pathological classification of intrahepatic cholangiocarcinoma based on a new concept
    • 3010511 21191517 10.4254/wjh.v2.i12.419 (Epub 2010/12/31)
    • Nakanuma Y, Sato Y, Harada K, Sasaki M, Xu J, Ikeda H. Pathological classification of intrahepatic cholangiocarcinoma based on a new concept. World J Hepatol. 2010;2(12):419-27 (Epub 2010/12/31).
    • (2010) World J Hepatol , vol.2 , Issue.12 , pp. 419-427
    • Nakanuma, Y.1    Sato, Y.2    Harada, K.3    Sasaki, M.4    Xu, J.5    Ikeda, H.6
  • 16
    • 79959572626 scopus 로고    scopus 로고
    • Risk factors for cholangiocarcinoma
    • 1:CAS:528:DC%2BC3MXnvF2nurk%3D 3125451 21488076 10.1002/hep.24351 (Epub 2011/04/14)
    • Tyson GL, El-Serag HB. Risk factors for cholangiocarcinoma. Hepatology. 2011;54(1):173-84 (Epub 2011/04/14).
    • (2011) Hepatology , vol.54 , Issue.1 , pp. 173-184
    • Tyson, G.L.1    El-Serag, H.B.2
  • 17
    • 40149088465 scopus 로고    scopus 로고
    • Opisthorchis viverrini: The carcinogenic human liver fluke
    • 1:CAS:528:DC%2BD1cXjsFyks7s%3D 18205254 10.3748/wjg.14.666 (Epub 2008/01/22)
    • Kaewpitoon N, Kaewpitoon SJ, Pengsaa P, Sripa B. Opisthorchis viverrini: the carcinogenic human liver fluke. WJG. 2008;14(5):666-74 (Epub 2008/01/22).
    • (2008) WJG , vol.14 , Issue.5 , pp. 666-674
    • Kaewpitoon, N.1    Kaewpitoon, S.J.2    Pengsaa, P.3    Sripa, B.4
  • 18
    • 0029973585 scopus 로고    scopus 로고
    • Hepatitis B and C virus, Clonorchis sinensis for the risk of liver cancer: A case-control study in Pusan, Korea
    • 1:STN:280:DyaK2s%2FnvFOltA%3D%3D 8921477 10.1093/ije/25.5.933 (Epub 1996/10/01)
    • Shin HR, Lee CU, Park HJ, Seol SY, Chung JM, Choi HC, et al. Hepatitis B and C virus, Clonorchis sinensis for the risk of liver cancer: a case-control study in Pusan, Korea. Int J Epidemiol. 1996;25(5):933-40 (Epub 1996/10/01).
    • (1996) Int J Epidemiol , vol.25 , Issue.5 , pp. 933-940
    • Shin, H.R.1    Lee, C.U.2    Park, H.J.3    Seol, S.Y.4    Chung, J.M.5    Choi, H.C.6
  • 19
    • 27744563358 scopus 로고    scopus 로고
    • Genetic and environmental determinants of risk for cholangiocarcinoma via Opisthorchis viverrini in a densely infested area in Nakhon Phanom, northeast Thailand
    • 1:CAS:528:DC%2BD2MXht1ShsbfK 15957169 10.1002/ijc.21146 (Epub 2005/06/16)
    • Honjo S, Srivatanakul P, Sriplung H, Kikukawa H, Hanai S, Uchida K, et al. Genetic and environmental determinants of risk for cholangiocarcinoma via Opisthorchis viverrini in a densely infested area in Nakhon Phanom, northeast Thailand. Int J Cancer. 2005;117(5):854-60 (Epub 2005/06/16).
    • (2005) Int J Cancer , vol.117 , Issue.5 , pp. 854-860
    • Honjo, S.1    Srivatanakul, P.2    Sriplung, H.3    Kikukawa, H.4    Hanai, S.5    Uchida, K.6
  • 20
    • 10244229159 scopus 로고    scopus 로고
    • Bile duct cysts in adults
    • 1:STN:280:DC%2BD2cnisVOrtw%3D%3D 10.1002/bjs.4815 (Epub 2004/11/19)
    • Soreide K, Korner H, Havnen J, Soreide JA. Bile duct cysts in adults. British J Surg. 2004;91(12):1538-48 (Epub 2004/11/19).
    • (2004) British J Surg , vol.91 , Issue.12 , pp. 1538-1548
    • Soreide, K.1    Korner, H.2    Havnen, J.3    Soreide, J.A.4
  • 21
    • 84879786324 scopus 로고    scopus 로고
    • Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane
    • 1:CAS:528:DC%2BC3sXhtFOlurjM 23493378 10.1136/oemed-2012-101246 (Epub 2013/03/16)
    • Kumagai S, Kurumatani N, Arimoto A, Ichihara G. Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane. Occup Environ Med. 2013;70(7):508-10 (Epub 2013/03/16).
    • (2013) Occup Environ Med , vol.70 , Issue.7 , pp. 508-510
    • Kumagai, S.1    Kurumatani, N.2    Arimoto, A.3    Ichihara, G.4
  • 22
    • 84892817074 scopus 로고    scopus 로고
    • Asbestos: A hidden player behind the cholangiocarcinoma increase? Findings from a case-control analysis
    • 3631123 23408245 (Epub 2013/02/15)
    • Brandi G, Di Girolamo S, Farioli A, de Rosa F, Curti S, Pinna AD, et al. Asbestos: a hidden player behind the cholangiocarcinoma increase? Findings from a case-control analysis. CCC. 2013;24(5):911-8 (Epub 2013/02/15).
    • (2013) CCC , vol.24 , Issue.5 , pp. 911-918
    • Brandi, G.1    Di Girolamo, S.2    Farioli, A.3    De Rosa, F.4    Curti, S.5    Pinna, A.D.6
  • 23
    • 0035683092 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma and hepatitis C and B virus infection, alcohol intake, and hepatolithiasis: A case-control study in Italy
    • 1:STN:280:DC%2BD38%2Fot1GltQ%3D%3D 11808716 (Epub 2002/01/26)
    • Donato F, Gelatti U, Tagger A, Favret M, Ribero ML, Callea F, et al. Intrahepatic cholangiocarcinoma and hepatitis C and B virus infection, alcohol intake, and hepatolithiasis: a case-control study in Italy. CCC. 2001;12(10):959-64 (Epub 2002/01/26).
    • (2001) CCC , vol.12 , Issue.10 , pp. 959-964
    • Donato, F.1    Gelatti, U.2    Tagger, A.3    Favret, M.4    Ribero, M.L.5    Callea, F.6
  • 24
    • 58949095678 scopus 로고    scopus 로고
    • Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. Veterans
    • 2719902 19085911 10.1002/hep.22606 (Epub 2008/12/17)
    • El-Serag HB, Engels EA, Landgren O, Chiao E, Henderson L, Amaratunge HC, et al. Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: a population-based study of U.S. veterans. Hepatology. 2009;49(1):116-23 (Epub 2008/12/17).
    • (2009) Hepatology , vol.49 , Issue.1 , pp. 116-123
    • El-Serag, H.B.1    Engels, E.A.2    Landgren, O.3    Chiao, E.4    Henderson, L.5    Amaratunge, H.C.6
  • 25
    • 50649112820 scopus 로고    scopus 로고
    • Hepatitis B virus infection and intrahepatic cholangiocarcinoma in Korea: A case-control study
    • 18557716 10.1111/j.1572-0241.2008.01796.x
    • Lee TY, Lee SS, Jung SW, Jeon SH, Yun SC, Oh HC, et al. Hepatitis B virus infection and intrahepatic cholangiocarcinoma in Korea: a case-control study. Am J Gastroenterol. 2008;103(7):1716-20.
    • (2008) Am J Gastroenterol , vol.103 , Issue.7 , pp. 1716-1720
    • Lee, T.Y.1    Lee, S.S.2    Jung, S.W.3    Jeon, S.H.4    Yun, S.C.5    Oh, H.C.6
  • 26
    • 15744389434 scopus 로고    scopus 로고
    • Risk factors of intrahepatic cholangiocarcinoma in the United States: A case-control study
    • 15765398 10.1053/j.gastro.2004.12.048 (Epub 2005/03/15)
    • Shaib YH, El-Serag HB, Davila JA, Morgan R, McGlynn KA. Risk factors of intrahepatic cholangiocarcinoma in the United States: a case-control study. Gastroenterology. 2005;128(3):620-6 (Epub 2005/03/15).
    • (2005) Gastroenterology , vol.128 , Issue.3 , pp. 620-626
    • Shaib, Y.H.1    El-Serag, H.B.2    Davila, J.A.3    Morgan, R.4    McGlynn, K.A.5
  • 27
    • 4143131235 scopus 로고    scopus 로고
    • Hepatitis C virus infection as a likely etiology of intrahepatic cholangiocarcinoma
    • 1:CAS:528:DC%2BD2cXnt1WjsbY%3D 15245596 10.1111/j.1349-7006.2004.tb02492. x (Epub 2004/07/13)
    • Yamamoto S, Kubo S, Hai S, Uenishi T, Yamamoto T, Shuto T, et al. Hepatitis C virus infection as a likely etiology of intrahepatic cholangiocarcinoma. Cancer Sci. 2004;95(7):592-5 (Epub 2004/07/13).
    • (2004) Cancer Sci , vol.95 , Issue.7 , pp. 592-595
    • Yamamoto, S.1    Kubo, S.2    Hai, S.3    Uenishi, T.4    Yamamoto, T.5    Shuto, T.6
  • 28
    • 79957884920 scopus 로고    scopus 로고
    • Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression
    • Yu TH, Yuan RH, Chen YL, Yang WC, Hsu HC, Jeng YM. Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression. Mod Pathol. 24(6):810-9.
    • Mod Pathol , vol.24 , Issue.6 , pp. 810-819
    • Yu, T.H.1    Yuan, R.H.2    Chen, Y.L.3    Yang, W.C.4    Hsu, H.C.5    Jeng, Y.M.6
  • 29
    • 40049092296 scopus 로고    scopus 로고
    • Risk factors for intrahepatic cholangiocarcinoma: A case-control study in China
    • 18203300 10.3748/wjg.14.632 (Epub 2008/01/19)
    • Zhou YM, Yin ZF, Yang JM, Li B, Shao WY, Xu F, et al. Risk factors for intrahepatic cholangiocarcinoma: a case-control study in China. WJG. 2008;14(4):632-5 (Epub 2008/01/19).
    • (2008) WJG , vol.14 , Issue.4 , pp. 632-635
    • Zhou, Y.M.1    Yin, Z.F.2    Yang, J.M.3    Li, B.4    Shao, W.Y.5    Xu, F.6
  • 30
    • 84862660912 scopus 로고    scopus 로고
    • Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma
    • 3804834 22420979 10.1016/j.jhep.2012.02.022 (Epub 2012/03/17)
    • Palmer WC, Patel T. Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma. J Hepatol. 2012;57(1):69-76 (Epub 2012/03/17).
    • (2012) J Hepatol , vol.57 , Issue.1 , pp. 69-76
    • Palmer, W.C.1    Patel, T.2
  • 31
    • 84859441690 scopus 로고    scopus 로고
    • Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors
    • 1:CAS:528:DC%2BC38XltVyqsrY%3D 3413201 22178589 10.1053/j.gastro.2011.12. 005 (Epub 2011/12/20) e15
    • Andersen JB, Spee B, Blechacz BR, Avital I, Komuta M, Barbour A, et al. Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors. Gastroenterology. 2012;142(4):1021-1031 e15 (Epub 2011/12/20).
    • (2012) Gastroenterology , vol.142 , Issue.4 , pp. 1021-1031
    • Andersen, J.B.1    Spee, B.2    Blechacz, B.R.3    Avital, I.4    Komuta, M.5    Barbour, A.6
  • 32
    • 84859927304 scopus 로고    scopus 로고
    • Genetic profiling of intrahepatic cholangiocarcinoma
    • 1:CAS:528:DC%2BC38Xls1Snt7o%3D 22395571 10.1097/MOG.0b013e3283523c7e (Epub 2012/03/08)
    • Andersen JB, Thorgeirsson SS. Genetic profiling of intrahepatic cholangiocarcinoma. Curr Opin Gastroenterol. 2012;28(3):266-72 (Epub 2012/03/08).
    • (2012) Curr Opin Gastroenterol , vol.28 , Issue.3 , pp. 266-272
    • Andersen, J.B.1    Thorgeirsson, S.S.2
  • 33
    • 84875237481 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma: Pathogenesis and rationale for molecular therapies
    • (Epub 2013/01/16)
    • Sia D, Tovar V, Moeini A, Llovet JM. Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. Oncogene. 2013 (Epub 2013/01/16).
    • (2013) Oncogene
    • Sia, D.1    Tovar, V.2    Moeini, A.3    Llovet, J.M.4
  • 34
    • 77951037177 scopus 로고    scopus 로고
    • Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma
    • 1:CAS:528:DC%2BC3cXkslShsLw%3D 3498758 20395200 10.1158/0008-5472.CAN-09- 2823 (Epub 2010/04/17)
    • Woo HG, Lee JH, Yoon JH, Kim CY, Lee HS, Jang JJ, et al. Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma. Cancer Res. 2010;70(8):3034-41 (Epub 2010/04/17).
    • (2010) Cancer Res , vol.70 , Issue.8 , pp. 3034-3041
    • Woo, H.G.1    Lee, J.H.2    Yoon, J.H.3    Kim, C.Y.4    Lee, H.S.5    Jang, J.J.6
  • 35
    • 84868204026 scopus 로고    scopus 로고
    • Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of mir-200c and EMT in intrahepatic cholangiocarcinoma
    • (Epub 2012/06/19)
    • Oishi N, Kumar MR, Roessler S, Ji J, Forgues M, Budhu A, et al. Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of mir-200c and EMT in intrahepatic cholangiocarcinoma. Hepatology. 2012 (Epub 2012/06/19).
    • (2012) Hepatology
    • Oishi, N.1    Kumar, M.R.2    Roessler, S.3    Ji, J.4    Forgues, M.5    Budhu, A.6
  • 36
    • 33645742425 scopus 로고    scopus 로고
    • A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
    • 1:CAS:528:DC%2BD28XjtFKjtLg%3D 16532004 10.1038/nm1377 (Epub 2006/03/15)
    • Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med. 2006;12(4):410-6 (Epub 2006/03/15).
    • (2006) Nat Med , vol.12 , Issue.4 , pp. 410-416
    • Lee, J.S.1    Heo, J.2    Libbrecht, L.3    Chu, I.S.4    Kaposi-Novak, P.5    Calvisi, D.F.6
  • 37
    • 84875244110 scopus 로고    scopus 로고
    • Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes
    • 1:CAS:528:DC%2BC3sXksV2jsL4%3D 23295441 10.1053/j.gastro.2013.01.001 (Epub 2013/01/09)
    • Sia D, Hoshida Y, Villanueva A, Roayaie S, Ferrer J, Tabak B, et al. Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes. Gastroenterology. 2013;144(4):829-40 (Epub 2013/01/09).
    • (2013) Gastroenterology , vol.144 , Issue.4 , pp. 829-840
    • Sia, D.1    Hoshida, Y.2    Villanueva, A.3    Roayaie, S.4    Ferrer, J.5    Tabak, B.6
  • 38
    • 84655169986 scopus 로고    scopus 로고
    • The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma
    • 1:CAS:528:DC%2BC3MXhs1Omt7%2FJ 10.1038/nrgastro.2011.222 (Epub 2011/12/07)
    • Sirica AE. The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma. Nat Rev Gastroenterol Hepatol. 2012;9(1):44-54 (Epub 2011/12/07).
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , Issue.1 , pp. 44-54
    • Sirica, A.E.1
  • 39
    • 84878781242 scopus 로고    scopus 로고
    • Identification of targetable FGFR gene fusions in diverse cancers
    • 1:CAS:528:DC%2BC3sXptVOrt7s%3D 3694764 23558953 10.1158/2159-8290.CD-13- 0050 (Epub 2013/04/06)
    • Wu YM, Su F, Kalyana-Sundaram S, Khazanov N, Ateeq B, Cao X, et al. Identification of targetable FGFR gene fusions in diverse cancers. Cancer Discov. 2013;3(6):636-47 (Epub 2013/04/06).
    • (2013) Cancer Discov , vol.3 , Issue.6 , pp. 636-647
    • Wu, Y.M.1    Su, F.2    Kalyana-Sundaram, S.3    Khazanov, N.4    Ateeq, B.5    Cao, X.6
  • 40
    • 84878985394 scopus 로고    scopus 로고
    • A critical role for notch signaling in the formation of cholangiocellular carcinomas
    • 1:CAS:528:DC%2BC3sXoslSjsbY%3D 23727022 10.1016/j.ccr.2013.04.019 (Epub 2013/06/04)
    • Zender S, Nickeleit I, Wuestefeld T, Sorensen I, Dauch D, Bozko P, et al. A critical role for notch signaling in the formation of cholangiocellular carcinomas. Cancer Cell. 2013;23(6):784-95 (Epub 2013/06/04).
    • (2013) Cancer Cell , vol.23 , Issue.6 , pp. 784-795
    • Zender, S.1    Nickeleit, I.2    Wuestefeld, T.3    Sorensen, I.4    Dauch, D.5    Bozko, P.6
  • 41
    • 84864773126 scopus 로고    scopus 로고
    • Cholangiocarcinomas can originate from hepatocytes in mice
    • 1:CAS:528:DC%2BC38Xht1SisrjE 3408746 22797301 10.1172/JCI63212 (Epub 2012/07/17)
    • Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, et al. Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest. 2012;122(8):2911-5 (Epub 2012/07/17).
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2911-2915
    • Fan, B.1    Malato, Y.2    Calvisi, D.F.3    Naqvi, S.4    Razumilava, N.5    Ribback, S.6
  • 42
    • 84868625552 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes
    • (Epub 2012/10/02)
    • Sekiya S, Suzuki A. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest. 2012 (Epub 2012/10/02).
    • (2012) J Clin Invest
    • Sekiya, S.1    Suzuki, A.2
  • 43
    • 79958765677 scopus 로고    scopus 로고
    • Downregulation of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) is associated with enhanced expression of matrix metalloproteinases and cholangiocarcinoma metastases
    • 1:CAS:528:DC%2BC3MXlvFOjs74%3D 21076843 10.1007/s00535-010-0345-y (Epub 2010/11/16)
    • Namwat N, Puetkasichonpasutha J, Loilome W, Yongvanit P, Techasen A, Puapairoj A, et al. Downregulation of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) is associated with enhanced expression of matrix metalloproteinases and cholangiocarcinoma metastases. J Gastroenterol. 2011;46(5):664-75 (Epub 2010/11/16).
    • (2011) J Gastroenterol , vol.46 , Issue.5 , pp. 664-675
    • Namwat, N.1    Puetkasichonpasutha, J.2    Loilome, W.3    Yongvanit, P.4    Techasen, A.5    Puapairoj, A.6
  • 44
    • 38049152791 scopus 로고    scopus 로고
    • Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes
    • 1:CAS:528:DC%2BD1cXksVKnsQ%3D%3D 17621267 10.1038/sj.onc.1210648 (Epub 2007/07/11)
    • Meng F, Wehbe-Janek H, Henson R, Smith H, Patel T. Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. Oncogene. 2008;27(3):378-86 (Epub 2007/07/11).
    • (2008) Oncogene , vol.27 , Issue.3 , pp. 378-386
    • Meng, F.1    Wehbe-Janek, H.2    Henson, R.3    Smith, H.4    Patel, T.5
  • 45
    • 33751280992 scopus 로고    scopus 로고
    • Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression
    • 1:CAS:528:DC%2BD28XhtFGjsrbL 17079474 10.1158/0008-5472.CAN-06-2130 (Epub 2006/11/03)
    • Wehbe H, Henson R, Meng F, Mize-Berge J, Patel T. Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression. Cancer Res. 2006;66(21):10517-24 (Epub 2006/11/03).
    • (2006) Cancer Res , vol.66 , Issue.21 , pp. 10517-10524
    • Wehbe, H.1    Henson, R.2    Meng, F.3    Mize-Berge, J.4    Patel, T.5
  • 46
    • 33846200831 scopus 로고    scopus 로고
    • Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing
    • 1:CAS:528:DC%2BD2sXit1aqt74%3D 2203612 17241887 10.1053/j.gastro.2006.10. 037 (Epub 2007/01/24)
    • Isomoto H, Mott JL, Kobayashi S, Werneburg NW, Bronk SF, Haan S, et al. Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. Gastroenterology. 2007;132(1):384-96 (Epub 2007/01/24).
    • (2007) Gastroenterology , vol.132 , Issue.1 , pp. 384-396
    • Isomoto, H.1    Mott, J.L.2    Kobayashi, S.3    Werneburg, N.W.4    Bronk, S.F.5    Haan, S.6
  • 47
    • 78650718355 scopus 로고    scopus 로고
    • Targeting the IL-6 dependent phenotype can identify novel therapies for cholangiocarcinoma
    • (Epub 2010/12/24)
    • Braconi C, Swenson E, Kogure T, Huang N, Patel T. Targeting the IL-6 dependent phenotype can identify novel therapies for cholangiocarcinoma. PloS one. 2010;5(12):e15195 (Epub 2010/12/24).
    • (2010) PloS One , vol.5 , Issue.12
    • Braconi, C.1    Swenson, E.2    Kogure, T.3    Huang, N.4    Patel, T.5
  • 48
    • 84896736106 scopus 로고    scopus 로고
    • Developments of treatment of advanced intrahepatic cholangiocarcinoma: An analysis of systemic and local therapy modes in 57 patients
    • abstr 346
    • Stuebs P, Habermann P, Garlipp B, Schuette K, Zierau K, Lippert H, et al. Developments of treatment of advanced intrahepatic cholangiocarcinoma: an analysis of systemic and local therapy modes in 57 patients. J Clin Oncol. 2012;30(Suppl 4):abstr 346.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL. 4
    • Stuebs, P.1    Habermann, P.2    Garlipp, B.3    Schuette, K.4    Zierau, K.5    Lippert, H.6
  • 49
    • 0029816590 scopus 로고    scopus 로고
    • Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer
    • 1:STN:280:DyaK2s%2FjtlOitw%3D%3D 8879373 10.1093/oxfordjournals.annonc. a010676
    • Glimelius B, Hoffman K, Sjoden PO, Jacobsson G, Sellstrom H, Enander LK, et al. Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol. 1996;7(6):593-600.
    • (1996) Ann Oncol , vol.7 , Issue.6 , pp. 593-600
    • Glimelius, B.1    Hoffman, K.2    Sjoden, P.O.3    Jacobsson, G.4    Sellstrom, H.5    Enander, L.K.6
  • 50
    • 1842555346 scopus 로고    scopus 로고
    • Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: A randomised phase II trial
    • 1:STN:280:DC%2BD2c7gvVektA%3D%3D 14998852 10.1093/annonc/mdh096
    • Kornek GV, Schuell B, Laengle F, Gruenberger T, Penz M, Karall K, et al. Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: a randomised phase II trial. Ann Oncol. 2004;15(3):478-83.
    • (2004) Ann Oncol , vol.15 , Issue.3 , pp. 478-483
    • Kornek, G.V.1    Schuell, B.2    Laengle, F.3    Gruenberger, T.4    Penz, M.5    Karall, K.6
  • 51
    • 19944433180 scopus 로고    scopus 로고
    • A randomised phase II trial of weekly high-dose 5-fluorouracil with and without folinic acid and cisplatin in patients with advanced biliary tract carcinoma: Results of the 40955 EORTC trial
    • 1:CAS:528:DC%2BD2MXhtVGqtLg%3D 15691639 10.1016/j.ejca.2004.10.026 (Epub 2005/02/05)
    • Ducreux M, Van Cutsem E, Van Laethem JL, Gress TM, Jeziorski K, Rougier P, et al. A randomised phase II trial of weekly high-dose 5-fluorouracil with and without folinic acid and cisplatin in patients with advanced biliary tract carcinoma: results of the 40955 EORTC trial. Eur J Cancer. 2005;41(3):398-403 (Epub 2005/02/05).
    • (2005) Eur J Cancer , vol.41 , Issue.3 , pp. 398-403
    • Ducreux, M.1    Van Cutsem, E.2    Van Laethem, J.L.3    Gress, T.M.4    Jeziorski, K.5    Rougier, P.6
  • 52
    • 19944380109 scopus 로고    scopus 로고
    • Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU (ECF) in previously untreated patients with advanced biliary cancer
    • 1:CAS:528:DC%2BD2MXjvVantrs%3D 2362051 15856037 10.1038/sj.bjc.6602576
    • Rao S, Cunningham D, Hawkins RE, Hill ME, Smith D, Daniel F, et al. Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU (ECF) in previously untreated patients with advanced biliary cancer. Br J Cancer. 2005;92(9):1650-4.
    • (2005) Br J Cancer , vol.92 , Issue.9 , pp. 1650-1654
    • Rao, S.1    Cunningham, D.2    Hawkins, R.E.3    Hill, M.E.4    Smith, D.5    Daniel, F.6
  • 53
    • 0032415443 scopus 로고    scopus 로고
    • Prospective randomized trial of 5-fluorouracil, doxorubicin, and mitomycin C for non-resectable pancreatic and biliary carcinoma: Multicenter randomized trial
    • 1:CAS:528:DyaK1MXhtFKjsbc%3D 9951857 (Epub 1999/02/10)
    • Takada T, Nimura Y, Katoh H, Nagakawa T, Nakayama T, Matsushiro T, et al. Prospective randomized trial of 5-fluorouracil, doxorubicin, and mitomycin C for non-resectable pancreatic and biliary carcinoma: multicenter randomized trial. Hepatogastroenterology. 1998;45(24):2020-6 (Epub 1999/02/10).
    • (1998) Hepatogastroenterology , vol.45 , Issue.24 , pp. 2020-2026
    • Takada, T.1    Nimura, Y.2    Katoh, H.3    Nagakawa, T.4    Nakayama, T.5    Matsushiro, T.6
  • 54
    • 77950822827 scopus 로고    scopus 로고
    • Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer
    • 1:CAS:528:DC%2BC3cXksVyiuro%3D 20375404 10.1056/NEJMoa0908721
    • Valle J, Wasan H, Palmer DH, Cunningham D, Anthoney A, Maraveyas A, et al. Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer. N Engl J Med. 2010;362(14):1273-81.
    • (2010) N Engl J Med , vol.362 , Issue.14 , pp. 1273-1281
    • Valle, J.1    Wasan, H.2    Palmer, D.H.3    Cunningham, D.4    Anthoney, A.5    Maraveyas, A.6
  • 55
    • 68749119637 scopus 로고    scopus 로고
    • Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: A multicentre randomised phase II study - The UK ABC-01 Study
    • 1:CAS:528:DC%2BD1MXpvFyisL8%3D 2736816 19672264 10.1038/sj.bjc.6605211 (Epub 2009/08/13)
    • Valle JW, Wasan H, Johnson P, Jones E, Dixon L, Swindell R, et al. Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: a multicentre randomised phase II study - The UK ABC-01 Study. Br J Cancer. 2009;101(4):621-7 (Epub 2009/08/13).
    • (2009) Br J Cancer , vol.101 , Issue.4 , pp. 621-627
    • Valle, J.W.1    Wasan, H.2    Johnson, P.3    Jones, E.4    Dixon, L.5    Swindell, R.6
  • 56
    • 79960262036 scopus 로고    scopus 로고
    • Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells
    • 1:CAS:528:DC%2BC3MXns12mtL8%3D 21331764 10.1007/s00535-011-0380-3 (Epub 2011/02/19)
    • Sugiyama H, Onuki K, Ishige K, Baba N, Ueda T, Matsuda S, et al. Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells. J Gastroenterol. 2011;46(6):779-89 (Epub 2011/02/19).
    • (2011) J Gastroenterol , vol.46 , Issue.6 , pp. 779-789
    • Sugiyama, H.1    Onuki, K.2    Ishige, K.3    Baba, N.4    Ueda, T.5    Matsuda, S.6
  • 57
    • 84879224082 scopus 로고    scopus 로고
    • Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions
    • (Epub 2013/02/09)
    • Voss JS, Holtegaard LM, Kerr SE, Fritcher EG, Roberts LR, Gores GJ, et al. Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions. Human pathology. 2013 (Epub 2013/02/09).
    • (2013) Human Pathology
    • Voss, J.S.1    Holtegaard, L.M.2    Kerr, S.E.3    Fritcher, E.G.4    Roberts, L.R.5    Gores, G.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.