The overexpression of 14-3-3ζ and Hsp27 promotes non-small cell lung cancer progression

Cancer

Volumn 120, Issue 5, 2014, Pages 652-663

  Zhao, Guang Yin ^a   Ding, Jian Yong ^a   Gu, Jie ^a   Lu, Chun Lai ^a   Lin, Zong Wu ^a   Guo, Jing ^a   Ge, Di ^a  

^a ZHONGSHAN HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

14 3 3 ; biomarker; heat shock protein 27; non small cell lung cancer

Indexed keywords

14 3 3 ZETA PROTEIN; COMPLEMENTARY DNA; HEAT SHOCK PROTEIN 27; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER PROGNOSIS; COMPLEX FORMATION; CONTROLLED STUDY; DNA TRANSFECTION; FEMALE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; METASTASIS; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; SURVIVAL RATE; SURVIVAL TIME; TUMOR INVASION; TUMOR PROMOTION;

14-3-3 PROTEINS; ADULT; AMINO ACID SEQUENCE; ANALYSIS OF VARIANCE; BLOTTING, WESTERN; CADHERINS; CARCINOMA, NON-SMALL-CELL LUNG; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP27 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MAP KINASE SIGNALING SYSTEM; MASS SPECTROMETRY; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84896722899     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.28452     Document Type: Article

References (38)

1. Jemal A, Siegel R, Xu J, Ward E,. Cancer statistics, 2010. CA Cancer J Clin. 2010; 60: 277-300.
2. Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010; 127: 2893-2917.
3. Fu H, Subramanian RR, Masters SC,. 14-3-3 proteins: structure, function, and regulation. Annu Rev Pharmacol Toxicol. 2000; 40: 617-647.
4. Aitken A, Collinge DB, van Heusden BP, et al. 14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins. Trends Biochem Sci. 1992; 17: 498-501.
5. Li Z, Zhao J, Du Y, et al. Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation. Proc Natl Acad Sci U S A. 2008; 105: 162-167.
6. Zhao J, Du Y, Horton JR, et al. Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor. Proc Natl Acad Sci U S A. 2011; 108: 16212-16216.
7. Tzivion G, Gupta VS, Kaplun L, Balan V,. 14-3-3 proteins as potential oncogenes. Semin Cancer Biol. 2006; 16: 203-213.
8. Hong HY, Jeon WK, Bae EJ, et al. 14-3-3 sigma and 14-3-3 zeta plays an opposite role in cell growth inhibition mediated by transforming growth factor-beta 1. Mol Cells. 2010; 29: 305-309.
9. Clark GJ, Drugan JK, Rossman KL, et al. 14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain. J Biol Chem. 1997; 272: 20990-20993.
10. Wilker E, Yaffe MB,. 14-3-3 Proteins-a focus on cancer and human disease. J Mol Cell Cardiol. 2004; 37: 633-642.
11. Takahashi Y,. The 14-3-3 proteins: gene, gene expression, and function. Neurochem Res. 2003; 28: 1265-1273.
12. Fan T, Li R, Todd NW, et al. Up-regulation of 14-3-3zeta in lung cancer and its implication as prognostic and therapeutic target. Cancer Res. 2007; 67: 7901-7906.
13. Devbhandari RP, Shi GM, Ke AW, et al. Profiling of the tetraspanin CD151 web and conspiracy of CD151/integrin beta1 complex in the progression of hepatocellular carcinoma [serial online]. PLoS One. 2011; 6: e24901.
14. Huang XY, Ke AW, Shi GM, et al. alphaB-crystallin complexes with 14-3-3zeta to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma. Hepatology. 2013; 57: 2235-2247.
15. Shi GM, Ke AW, Zhou J, et al. CD151 modulates expression of matrix metalloproteinase 9 and promotes neoangiogenesis and progression of hepatocellular carcinoma. Hepatology. 2010; 52: 183-196.
16. Gu J, Ding JY, Lu CL, et al. Overexpression of CD88 predicts poor prognosis in non-small-cell lung cancer. Lung Cancer. 2013; 81: 259-265.
17. Satoh J, Onoue H, Arima K, Yamamura T,. The 14-3-3 protein forms a molecular complex with heat shock protein Hsp60 and cellular prion protein. J Neuropathol Exp Neurol. 2005; 64: 858-868.
18. Yano M, Nakamuta S, Wu X, Okumura Y, Kido H,. A novel function of 14-3-3 protein: 14-3-3zeta is a heat-shock-related molecular chaperone that dissolves thermal-aggregated proteins. Mol Biol Cell. 2006; 17: 4769-4779.
19. Ge F, Lu XP, Zeng HL, et al. Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells. J Proteome Res. 2009; 8: 3006-3019.
20. Matta A, Siu KM, Ralhan R,. 14-3-3 zeta as novel molecular target for cancer therapy [published online ahead of print April 18, 2012]. Expert Opin Ther Targets. 2012.
21. Malusecka E, Zborek A, Krzyzowska-Gruca S, Krawczyk Z,. Expression of heat shock proteins HSP70 and HSP27 in primary non-small cell lung carcinomas. An immunohistochemical study. Anticancer Res. 2001; 21: 1015-1021.
22. Zhao J, Meyerkord CL, Du Y, Khuri FR, Fu H,. 14-3-3 proteins as potential therapeutic targets. Semin Cell Dev Biol. 2011; 22: 705-712.
23. Obsil T,. 14-3-3 proteins-a family of universal scaffolds and regulators. Semin Cell Dev Biol. 2011; 22: 661-662.
24. Morrison DK,. The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol. 2009; 19: 16-23.
25. Singh LP, Jiang Y, Cheng DW,. Proteomic identification of 14-3-3zeta as an adapter for IGF-1 and Akt/GSK-3beta signaling and survival of renal mesangial cells. Int J Biol Sci. 2007; 3: 27-39.
26. Powell DW, Rane MJ, Joughin BA, et al. Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding. Mol Cell Biol. 2003; 23: 5376-5387.
27. Zoubeidi A, Gleave M,. Small heat shock proteins in cancer therapy and prognosis. Int J Biochem Cell Biol. 2012; 44: 1646-1656.
28. Acunzo J, Katsogiannou M, Rocchi P,. Small heat shock proteins HSP27 (HspB1), alphaB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death. Int J Biochem Cell Biol. 2012; 44: 1622-1631.
29. Reuther GW, Pendergast AM,. The roles of 14-3-3 proteins in signal transduction. Vitam Horm. 1996; 52: 149-175.
30. Darling DL, Yingling J, Wynshaw-Boris A,. Role of 14-3-3 proteins in eukaryotic signaling and development. Curr Top Dev Biol. 2005; 68: 281-315.
31. Lu J, Guo H, Treekitkarnmongkol W, et al. 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell. 2009; 16: 195-207.
32. Malusecka E, Krzyzowska-Gruca S, Gawrychowski J, et al. Stress proteins HSP27 and HSP70i predict survival in non-small cell lung carcinoma. Anticancer Res. 2008; 28: 501-506.
33. Straume O, Shimamura T, Lampa MJ, et al. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer. Proc Natl Acad Sci U S A. 2012; 109: 8699-8704.
34. Geisler JP, Tammela JE, Manahan KJ, et al. HSP27 in patients with ovarian carcinoma: still an independent prognostic indicator at 60 months follow-up. Eur J Gynaecol Oncol. 2004; 25: 165-168.
35. Garrido C, Fromentin A, Bonnotte B, et al. Heat shock protein 27 enhances the tumorigenicity of immunogenic rat colon carcinoma cell clones. Cancer Res. 1998; 58: 5495-5499.
36. Lopes LB, Furnish EJ, Komalavilas P, et al. Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts. J Invest Dermatol. 2009; 129: 590-598.
37. Lim J, Thiery JP,. Epithelial-mesenchymal transitions: insights from development. Development. 2012; 139: 3471-3486.
38. Zeisberg M, Neilson EG,. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest. 2009; 119: 1429-1437.