Apogossypolone induces autophagy and apoptosis in breast cancer MCF-7 cells in vitro and in vivo

Breast Cancer

Volumn 21, Issue 2, 2014, Pages 223-230

  Niu, Xiaoge ^a   Li, Shaobin ^a   Wei, Fang ^a   Huang, Jie ^a   Wu, Gang ^a   Xu, Liang ^b   Xu, Dongsheng ^c   Wang, Senming ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF KANSAS CANCER CENTER   (United States)

^c CBLPATH   (United States)

Author keywords

Apogossypolone; Apoptosis; Autophagy; Bcl 2; Breast cancer

Indexed keywords

APOGOSSYPOLONE; BECLIN 1; GOSSYPOL; GOSSYPOL DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; BAX PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; MEMBRANE PROTEIN;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; TRANSMISSION ELECTRON MICROSCOPY; ANALOGS AND DERIVATIVES; ANIMAL; BREAST NEOPLASMS; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; MCF 7 CELL LINE; METABOLISM; NUDE MOUSE; PATHOLOGY; ULTRASTRUCTURE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GOSSYPOL; HUMANS; MCF-7 CELLS; MEMBRANE PROTEINS; MICE, NUDE; PROTO-ONCOGENE PROTEINS C-BCL-2; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896719786     PISSN: 13406868     EISSN: 18804233     Source Type: Journal    
DOI: 10.1007/s12282-012-0372-z     Document Type: Article

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