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Volumn 192, Issue 4, 2014, Pages 1641-1650

Anti-CD79 antibody induces B cell anergy that protects against autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

CD79 MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 84896719232     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302672     Document Type: Article
Times cited : (33)

References (45)
  • 5
    • 74849131972 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
    • Merrill, J. T., C. M. Neuwelt, D. J. Wallace, J. C. Shanahan, K. M. Latinis, J. C. Oates, T. O. Utset, C. Gordon, D. A. Isenberg, H. J. Hsieh, et al. 2010. Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum. 62: 222-233.
    • (2010) Arthritis Rheum , vol.62 , pp. 222-233
    • Merrill, J.T.1    Neuwelt, C.M.2    Wallace, D.J.3    Shanahan, J.C.4    Latinis, K.M.5    Oates, J.C.6    Utset, T.O.7    Gordon, C.8    Isenberg, D.A.9    Hsieh, H.J.10
  • 9
    • 0036464611 scopus 로고    scopus 로고
    • The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
    • Byrd, J. C., S. Kitada, I. W. Flinn, J. L. Aron, M. Pearson, D. Lucas, and J. C. Reed. 2002. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction. Blood 99: 1038-1043.
    • (2002) Blood , vol.99 , pp. 1038-1043
    • Byrd, J.C.1    Kitada, S.2    Flinn, I.W.3    Aron, J.L.4    Pearson, M.5    Lucas, D.6    Reed, J.C.7
  • 10
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
    • Clynes, R. A., T. L. Towers, L. G. Presta, and J. V. Ravetch. 2000. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat. Med. 6: 443-446.
    • (2000) Nat. Med. , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 11
    • 0032030699 scopus 로고    scopus 로고
    • Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies
    • Shan, D., J. A. Ledbetter, and O. W. Press. 1998. Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies. Blood 91: 1644-1652.
    • (1998) Blood , vol.91 , pp. 1644-1652
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 15
    • 0036180868 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody (Rituximab) for life-threatening autoimmune haemolytic anaemia in a patient with systemic lupus erythematosus
    • Perrotta, S., F. Locatelli, A. LaManna, L. Cennamo, P. De Stefano, and B. Nobili. 2002. Anti-CD20 monoclonal antibody (Rituximab) for life-threatening autoimmune haemolytic anaemia in a patient with systemic lupus erythematosus. Br. J. Haematol. 116: 465-467.
    • (2002) Br. J. Haematol. , vol.116 , pp. 465-467
    • Perrotta, S.1    Locatelli, F.2    Lamanna, A.3    Cennamo, L.4    De Stefano, P.5    Nobili, B.6
  • 16
    • 0142087478 scopus 로고    scopus 로고
    • Successful long-term treatment of systemic lupus erythematosus with rituximab maintenance therapy
    • Weide, R., J. Heymanns, A. Pandorf, and H. Köppler. 2003. Successful long-term treatment of systemic lupus erythematosus with rituximab maintenance therapy. Lupus 12: 779-782.
    • (2003) Lupus , vol.12 , pp. 779-782
    • Weide, R.1    Heymanns, J.2    Pandorf, A.3    Köppler, H.4
  • 18
    • 70449701417 scopus 로고    scopus 로고
    • Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy
    • Browne, C. D., C. J. Del Nagro, M. H. Cato, H. S. Dengler, and R. C. Rickert. 2009. Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy. Immunity 31: 749-760.
    • (2009) Immunity , vol.31 , pp. 749-760
    • Browne, C.D.1    Del Nagro, C.J.2    Cato, M.H.3    Dengler, H.S.4    Rickert, R.C.5
  • 19
    • 27544458293 scopus 로고    scopus 로고
    • Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling
    • Gauld, S. B., R. J. Benschop, K. T. Merrell, and J. C. Cambier. 2005. Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling. Nat. Immunol. 6: 1160-1167.
    • (2005) Nat. Immunol. , vol.6 , pp. 1160-1167
    • Gauld, S.B.1    Benschop, R.J.2    Merrell, K.T.3    Cambier, J.C.4
  • 22
    • 81955161811 scopus 로고    scopus 로고
    • Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy
    • O'Neill, S. K., A. Getahun, S. B. Gauld, K. T. Merrell, I. Tamir, M. J. Smith, J. M. Dal Porto, Q. Z. Li, and J. C. Cambier. 2011. Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity 35: 746-756.
    • (2011) Immunity , vol.35 , pp. 746-756
    • O'Neill, S.K.1    Getahun, A.2    Gauld, S.B.3    Merrell, K.T.4    Tamir, I.5    Smith, M.J.6    Dal Porto, J.M.7    Li, Q.Z.8    Cambier, J.C.9
  • 23
    • 0011869916 scopus 로고
    • Clonal anergy: Persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen
    • Nossal, G. J., and B. L. Pike. 1980. Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen. Proc. Natl. Acad. Sci. USA 77: 1602-1606.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 1602-1606
    • Nossal, G.J.1    Pike, B.L.2
  • 24
    • 0035129651 scopus 로고    scopus 로고
    • Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive
    • Benschop, R. J., K. Aviszus, X. Zhang, T. Manser, J. C. Cambier, and L. J. Wysocki. 2001. Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity 14: 33-43.
    • (2001) Immunity , vol.14 , pp. 33-43
    • Benschop, R.J.1    Aviszus, K.2    Zhang, X.3    Manser, T.4    Cambier, J.C.5    Wysocki, L.J.6
  • 25
    • 0031604350 scopus 로고    scopus 로고
    • Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes
    • discussion 144-145, 186-190
    • Healy, J. I., R. E. Dolmetsch, R. S. Lewis, and C. C. Goodnow. 1998. Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes. Novartis Found. Symp. 215: 137-144; discussion 144-145, 186-190.
    • (1998) Novartis Found. Symp. , vol.215 , pp. 137-144
    • Healy, J.I.1    Dolmetsch, R.E.2    Lewis, R.S.3    Goodnow, C.C.4
  • 26
    • 0031183390 scopus 로고    scopus 로고
    • B cell antigen receptor desensitization: Disruption of receptor coupling to tyrosine kinase activation
    • Vilen, B. J., S. J. Famiglietti, A. M. Carbone, B. K. Kay, and J. C. Cambier. 1997. B cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activation. J. Immunol. 159: 231-243.
    • (1997) J. Immunol. , vol.159 , pp. 231-243
    • Vilen, B.J.1    Famiglietti, S.J.2    Carbone, A.M.3    Kay, B.K.4    Cambier, J.C.5
  • 27
    • 0037289807 scopus 로고    scopus 로고
    • The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus
    • Anolik, J. H., D. Campbell, R. E. Felgar, F. Young, I. Sanz, J. Rosenblatt, and R. J. Looney. 2003. The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus. Arthritis Rheum. 48: 455-459.
    • (2003) Arthritis Rheum , vol.48 , pp. 455-459
    • Anolik, J.H.1    Campbell, D.2    Felgar, R.E.3    Young, F.4    Sanz, I.5    Rosenblatt, J.6    Looney, R.J.7
  • 28
    • 78149474747 scopus 로고    scopus 로고
    • Although IL-6 transsignaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity
    • Lissilaa, R., V. Buatois, G. Magistrelli, A. S. Williams, G. W. Jones, S. Herren, L. Shang, P. Malinge, F. Guilhot, L. Chatel, et al. 2010. Although IL-6 transsignaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity. J. Immunol. 185: 5512-5521.
    • (2010) J. Immunol. , vol.185 , pp. 5512-5521
    • Lissilaa, R.1    Buatois, V.2    Magistrelli, G.3    Williams, A.S.4    Jones, G.W.5    Herren, S.6    Shang, L.7    Malinge, P.8    Guilhot, F.9    Chatel, L.10
  • 29
    • 84866148826 scopus 로고    scopus 로고
    • Retention of anergy and inhibition of antibody responses during acute g herpesvirus 68 infection
    • Getahun, A., M. J. Smith, I. Kogut, L. F. van Dyk, and J. C. Cambier. 2012. Retention of anergy and inhibition of antibody responses during acute g herpesvirus 68 infection. J. Immunol. 189: 2965-2974.
    • (2012) J. Immunol. , vol.189 , pp. 2965-2974
    • Getahun, A.1    Smith, M.J.2    Kogut, I.3    Van Dyk, L.F.4    Cambier, J.C.5
  • 30
    • 77955418167 scopus 로고    scopus 로고
    • Efficient production of human Fas receptor extracellular domain-human IgG1 heavy chain Fc domain fusion protein using baculovirus/silkworm expression system
    • Muraki, M., and S. Honda. 2010. Efficient production of human Fas receptor extracellular domain-human IgG1 heavy chain Fc domain fusion protein using baculovirus/silkworm expression system. Protein Expr. Purif. 73: 209-216.
    • (2010) Protein Expr. Purif. , vol.73 , pp. 209-216
    • Muraki, M.1    Honda, S.2
  • 33
    • 34548715943 scopus 로고    scopus 로고
    • B cell depletion delays collagen-induced arthritis in mice: Arthritis induction requires synergy between humoral and cell-mediated immunity
    • Yanaba, K., Y. Hamaguchi, G. M. Venturi, D. A. Steeber, E. W. St Clair, and T. F. Tedder. 2007. B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity. J. Immunol. 179: 1369-1380.
    • (2007) J. Immunol. , vol.179 , pp. 1369-1380
    • Yanaba, K.1    Hamaguchi, Y.2    Venturi, G.M.3    Steeber, D.A.4    St Clair, E.W.5    Tedder, T.F.6
  • 34
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • Uchida, J., Y. Hamaguchi, J. A. Oliver, J. V. Ravetch, J. C. Poe, K. M. Haas, and T. F. Tedder. 2004. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J. Exp. Med. 199: 1659-1669.
    • (2004) J. Exp. Med. , vol.199 , pp. 1659-1669
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3    Ravetch, J.V.4    Poe, J.C.5    Haas, K.M.6    Tedder, T.F.7
  • 35
    • 47249089061 scopus 로고    scopus 로고
    • B cell depletion inhibits spontaneous autoimmune thyroiditis in NOD.H-2h4 mice
    • Yu, S., R. Dunn, M. R. Kehry, and H. Braley-Mullen. 2008. B cell depletion inhibits spontaneous autoimmune thyroiditis in NOD.H-2h4 mice. J. Immunol. 180: 7706-7713.
    • (2008) J. Immunol. , vol.180 , pp. 7706-7713
    • Yu, S.1    Dunn, R.2    Kehry, M.R.3    Braley-Mullen, H.4
  • 37
    • 0034663163 scopus 로고    scopus 로고
    • SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization
    • Carver, D. J., M. J. Aman, and K. S. Ravichandran. 2000. SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization. Blood 96: 1449-1456.
    • (2000) Blood , vol.96 , pp. 1449-1456
    • Carver, D.J.1    Aman, M.J.2    Ravichandran, K.S.3
  • 39
    • 33746942234 scopus 로고    scopus 로고
    • Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis
    • Roll, P., A. Palanichamy, C. Kneitz, T. Dorner, and H. P. Tony. 2006. Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis. Arthritis Rheum. 54: 2377-2386.
    • (2006) Arthritis Rheum. , vol.54 , pp. 2377-2386
    • Roll, P.1    Palanichamy, A.2    Kneitz, C.3    Dorner, T.4    Tony, H.P.5
  • 40
    • 0027168420 scopus 로고
    • Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes
    • Bubien, J. K., L. J. Zhou, P. D. Bell, R. A. Frizzell, and T. F. Tedder. 1993. Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes. J. Cell Biol. 121: 1121-1132.
    • (1993) J. Cell Biol. , vol.121 , pp. 1121-1132
    • Bubien, J.K.1    Zhou, L.J.2    Bell, P.D.3    Frizzell, R.A.4    Tedder, T.F.5
  • 41
    • 0029913115 scopus 로고    scopus 로고
    • Regulation of an early developmental checkpoint in the B cell pathway by Ig beta
    • Gong, S., and M. C. Nussenzweig. 1996. Regulation of an early developmental checkpoint in the B cell pathway by Ig beta. Science 272: 411-414.
    • (1996) Science , vol.272 , pp. 411-414
    • Gong, S.1    Nussenzweig, M.C.2
  • 42
    • 0037100435 scopus 로고    scopus 로고
    • B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta
    • Pelanda, R., U. Braun, E. Hobeika, M. C. Nussenzweig, and M. Reth. 2002. B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta. J. Immunol. 169: 865-872.
    • (2002) J. Immunol. , vol.169 , pp. 865-872
    • Pelanda, R.1    Braun, U.2    Hobeika, E.3    Nussenzweig, M.C.4    Reth, M.5
  • 43
    • 0035803539 scopus 로고    scopus 로고
    • Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis
    • Bannish, G., E. M. Fuentes-Pananá, J. C. Cambier, W. S. Pear, and J. G. Monroe. 2001. Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis. J. Exp. Med. 194: 1583-1596.
    • (2001) J. Exp. Med. , vol.194 , pp. 1583-1596
    • Bannish, G.1    Fuentes-Pananá, E.M.2    Cambier, J.C.3    Pear, W.S.4    Monroe, J.G.5


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