Prostaglandin e2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression

International Journal of Oncology

Volumn 44, Issue 3, 2014, Pages 769-780

  Zhang, Hai ^a   Cheng, Shanyu ^a   Zhang, Min ^a   Ma, Xiuping ^a   Zhang, Li ^a   Wang, Yipin ^a   Rong, Rong ^a   Ma, Juan ^a   Xia, Shukai ^a   Du, Mingzhan ^a   Shi, Feng ^a   Wang, Jie ^a   Yang, Qinyi ^a   Bai, Xiaoming ^a   Leng, Jing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; Invasion; Prostaglandin E2; Y box binding protein 1

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; PROTEIN KINASE P60; PROTEIN P42; PROTEIN P44; Y BOX BINDING PROTEIN 1; YBX1 PROTEIN, HUMAN;

ARTICLE; CARCINOMA CELL; CELL INVASION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA INTERFERENCE; UPREGULATION; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DINOPROSTONE; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; NEOPLASM INVASIVENESS; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; Y-BOX-BINDING PROTEIN 1;

EID: 84896719071     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2234     Document Type: Article

References (45)

1. El-Serag HB and Rudolph KL: Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132: 2557-2576, 2007.
2. Berasain C, Castillo J, Perugorria MJ, Latasa MU, Prieto J and Avila MA: Inflammation and liver cancer: new molecular links. Ann NY Acad Sci 1155: 206-221, 2009.
3. Stauffer JK, Scarzello AJ, Jiang Q and Wiltrout RH: Chronic inflammation, immune escape and oncogenesis in the liver: a unique neighborhood for novel intersections. Hepatology 56: 1567-1574, 2012.
4. Hu KQ: Cyclooxygenase 2 (COX2)-prostanoid pathway and liver diseases. Prostaglandins Leukot Essent Fatty Acids 69: 329-337, 2003.
5. Wu T: Cyclooxygenase-2 in hepatocellular carcinoma. Cancer Treat Rev 32: 28-44, 2006.
6. 2 promotes liver cancer cell growth by the upregulation of FUSE-binding protein 1 expression. Int J Oncol 42: 1093-1104, 2013.
7. 2 upregulates survivin expression via the EP1 receptor in hepatocellular carcinoma cells. Life Sci 86: 214-223, 2009.
8. Gomes RN and Colquhoun A: E series prostaglandins alter the proliferative, apoptotic and migratory properties of T98G human glioma cells in vitro. Lipids Health Dis 11: 171, 2012.
9. 2 receptor EP1 phosphorylate CREB and mediates MMP2 expression in human cholangiocarcinoma cells. Mol Cell Biochem 378: 195-203, 2013.
10. Xin X, Majumder M, Girish GV, Mohindra V, Maruyama T and Lala PK: Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model. Lab Invest 92: 1115-1128, 2012.
11. Valastyan S and Weinberg RA: Tumor metastasis: molecular insights and evolving paradigms. Cell 147: 275-292, 2011.
12. Lasham A, Print CG, Woolley AG, Dunn SE and Braithwaite AW: YB-1: oncoprotein, prognostic marker and therapeutic target? Biochem J 449: 11-23, 2012.
13. Bargou RC, Jurchott K, Wagener C, et al: Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression. Nat Med 3: 447-450, 1997.
14. Shibahara K, Sugio K, Osaki T, et al: Nuclear expression of the Y-box binding protein, YB-1, as a novel marker of disease progression in non-small cell lung cancer. Clin Cancer Res 7: 3151-3155, 2001.
15. Gimenez-Bonafe P, Fedoruk MN, Whitmore TG, et al: YB-1 is upregulated during prostate cancer tumor progression and increases P-glycoprotein activity. Prostate 59: 337-349, 2004.
16. Lasham A, Samuel W, Cao H, et al: YB-1, the E2F pathway and regulation of tumor cell growth. J Natl Cancer Inst 104: 133-146, 2011.
17. Dahl E, En-Nia A, Wiesmann F, et al: Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer. BMC Cancer 9: 410, 2009.
18. Habibi G, Leung S, Law JH, et al: Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes. Breast Cancer Res 10: R86, 2008.
19. Huang J, Tan PH, Li KB, Matsumoto K, Tsujimoto M and Bay BH: Y-box binding protein, YB-1, as a marker of tumor aggressiveness and response to adjuvant chemotherapy in breast cancer. Int J Oncol 26: 607-613, 2005.
20. Evdokimova V, Tognon C, Ng T, et al: Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition. Cancer Cell 15: 402-415, 2009.
21. 2 receptor EP1-mediated phosphorylation of focal adhesion kinase enhances cell adhesion and migration in hepatocellular carcinoma cells. Int J Oncol 42: 1833-1841, 2013.
22. 2-mediated adhesion, migration and invasion in hepatocellular carcinoma cells. Oncol Rep 21: 129-136, 2009.
23. 2-mediated lung cancer metastasis. Cancer Res 73: 439-449, 2012.
24. Pai R, Nakamura T, Moon WS and Tarnawski AS: Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors. FASEB J 17: 1640-1647, 2003.
25. 2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem 277: 50828-50833, 2002.
26. Wu Y, Yamada S, Izumi H, et al: Strong YB-1 expression is associated with liver metastasis progression and predicts shorter disease-free survival in advanced gastric cancer. J Surg Oncol 105: 724-730, 2012.
27. Lovett DH, Cheng S, Cape L, Pollock AS and Mertens PR: YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis. Biochem Biophys Res Commun 398: 482-488, 2010.
28. 2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells. J Cell Physiol 207: 261-270, 2006.
29. 2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt. J Biol Chem 280: 24053-24063, 2005.
30. Caramel J, Papadogeorgakis E, Hill L, et al: A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma. Cancer Cell 24: 466-480, 2013.
31. Caslavsky J, Klimova Z and Vomastek T: ERK and RSK regulate distinct steps of a cellular program that induces transition from multicellular epithelium to single cell phenotype. Cell Signal 25: 2743-2751, 2013.
32. Weiss MB, Abel EV, Mayberry MM, Basile KJ, Berger AC and Aplin AE: TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells. Cancer Res 72: 6382-6392, 2012.
33. Laplante M and Sabatini DM: mTOR signaling in growth control and disease. Cell 149: 274-293, 2012.
34. Liu JF, Fong YC, Chang CS, et al: Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. Mol Cancer 9: 43, 2010.
35. Fidler IJ: The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 3: 453-458, 2003.
36. Chaffer CL and Weinberg RA: A perspective on cancer cell metastasis. Science 331: 1559-1564, 2011.
37. Thiery JP, Acloque H, Huang RY and Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890, 2009.
38. Matsumoto K and Wolffe AP: Gene regulation by Y-box proteins: coupling control of transcription and translation. Trends Cell Biol 8: 318-323, 1998.
39. Kuwano M, Uchiumi T, Hayakawa H, et al: The basic and clinical implications of ABC transporters, Y-box-binding protein-1 (YB-1) and angiogenesis-related factors in human malignancies. Cancer Sci 94: 9-14, 2003.
40. Evdokimova V, Ovchinnikov LP and Sorensen PH: Y-box binding protein 1: providing a new angle on translational regulation. Cell Cycle 5: 1143-1147, 2006.
41. Guo TT, Yu YN, Cheong Yip GW, Matsumoto K and Bay BH: Silencing the YB-1 gene inhibits cell migration in gastric cancer in vitro. Anat Rec 296: 891-898, 2013.
42. Delcourt N, Bockaert J and Marin P: GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation. Trends Pharmacol Sci 28: 602-607, 2007.
43. Santamaria PG and Nebreda AR: Deconstructing ERK signaling in tumorigenesis. Mol Cell 38: 3-5, 2010.
44. Ellenrieder V, Hendler SF, Boeck W, et al: Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. Cancer Res 61: 4222-4228, 2001.
45. Fujiwara-Okada Y, Matsumoto Y, Fukushi J, et al: Y-box binding protein-1 regulates cell proliferation and is associated with clinical outcomes of osteosarcoma. Br J Cancer 108: 836-847, 2013.