An efficient and convenient protocol for the synthesis of 1,1-difluoro-6-nitro-2,3-dihydro-1 H -indene derivatives

Synthesis (Germany)

Volumn 46, Issue 5, 2014, Pages 613-620

  Zhang, Dongfeng ^a   Li, Peng ^a   Lin, Ziyun ^a   Huang, Haihong ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

dithioketal; gem difluorination; indanone; substitution; synthesis

Indexed keywords

DITHIOKETAL; EFFICIENT SYNTHESIS; INDANONE; PLAUSIBLE MECHANISMS; SYNTHETIC ROUTES;

CHEMISTRY; SPEECH SYNTHESIS; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

POLYCYCLIC AROMATIC HYDROCARBONS;

1 (1,1 DIFLUORO 2,3 DIHYDRO 6 NITRO 1H INDEN 2 YL) 4 METHYLPIPERAZINE; 1 (1,1 DIFLUORO 2,3 DIHYDRO 6 NITRO 1H INDEN 2 YL)PYRROLIDINE; 1,1 DIFLUORO 2,3 DIHYDRO N ISOPROPYL 6 NITRO 1H INDEN 2 AMINE; 1,1 DIFLUORO 6 NITRO 1H INDENE; 1,1 DIFLUORO 6 NITRO 2,3 DIHYDRO 1H INDENE; 1,1 DIFLUORO 6 NITRO 2,3 DIHYDRO 1H INDENE DERIVATIVE; 2 BROMO 1,1 DIFLUORO 2,3 DIHYDRO 1H INDENE; 2 BROMO 1,1 DIFLUORO 4 NITRO 2,3 DIHYDRO 1H INDENE; 2 BROMO 1,1 DIFLUORO 6 NITRO 2,3 DIHYDRO 1H INDENE; 2 BROMO 6 CHLORO 1,1 DIFLUORO 6 NITRO 2,3 DIHYDRO 1H INDENE; 3 BROMO 1,1 DIFLUORO 6 NITRO 2,3 DIHYDRO 1H INDENE; 4 (1,1 DIFLUORO 2,3 DIHYDRO 6 NITRO 1H INDEN 2 YL)MORPHOLINE; BROMINE; FLUORIDE; INDENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; ELIMINATION REACTION; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTION;

EID: 84896718431     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1340595     Document Type: Article

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