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Volumn 20, Issue 1, 2014, Pages 54-61

Central nervous system antiretroviral penetration and cognitive functioning in largely pretreated HIV-infected patients

Author keywords

CNS; CPE; HIV; Neurocognitive; Penetration; Viral suppression

Indexed keywords

ABACAVIR PLUS LAMIVUDINE; ATAZANAVIR; DARUNAVIR; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; FOSAMPRENAVIR; LOPINAVIR; NEVIRAPINE; TENOFOVIR;

EID: 84896717958     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-013-0228-0     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 35848953181 scopus 로고    scopus 로고
    • Updated research nosology for HIV-associated neurocognitive disorders
    • 1:STN:280:DC%2BD2snktFyqsQ%3D%3D 17914061 10.1212/01.WNL.0000287431. 88658.8b
    • Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M et al (2007) Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69:1789-1799
    • (2007) Neurology , vol.69 , pp. 1789-1799
    • Antinori, A.1    Arendt, G.2    Becker, J.T.3    Brew, B.J.4    Byrd, D.A.5    Cherner, M.6
  • 2
    • 0037183960 scopus 로고    scopus 로고
    • Factors influencing virological response to antiretroviral drugs in cerebrospinal fluid of advanced HIV-1-infected patients
    • 1:CAS:528:DC%2BD38XnsVWmt7s%3D 12351946 10.1097/00002030-200209270-00003
    • Antinori A, Giancola ML, Grisetti S, Soldani F, Alba L, Liuzzi G et al (2002) Factors influencing virological response to antiretroviral drugs in cerebrospinal fluid of advanced HIV-1-infected patients. AIDS 16:1867-1876
    • (2002) AIDS , vol.16 , pp. 1867-1876
    • Antinori, A.1    Giancola, M.L.2    Grisetti, S.3    Soldani, F.4    Alba, L.5    Liuzzi, G.6
  • 3
    • 40449141429 scopus 로고    scopus 로고
    • Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapy
    • 17894380 10.1002/ana.21225
    • Bhaskaran K, Mussini C, Antinori A, Walker AS, Dorrucci M, Sabin C et al (2008) Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapy. Ann Neurol 63:213-221
    • (2008) Ann Neurol , vol.63 , pp. 213-221
    • Bhaskaran, K.1    Mussini, C.2    Antinori, A.3    Walker, A.S.4    Dorrucci, M.5    Sabin, C.6
  • 4
    • 76749136667 scopus 로고    scopus 로고
    • Discordances between cerebrospinal fluid and plasma replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy
    • 10.1086/650538 20100092 10.1086/650538
    • Canestri A, Lescure FX, Jaureguiberry S, Moulignier A, Amiel C, Marcelin AG et al (2010) Discordances between cerebrospinal fluid and plasma replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy. Clin Infect Dis 50:773-8. doi: 10.1086/650538
    • (2010) Clin Infect Dis , vol.50 , pp. 773-778
    • Canestri, A.1    Lescure, F.X.2    Jaureguiberry, S.3    Moulignier, A.4    Amiel, C.5    Marcelin, A.G.6
  • 5
    • 12144263094 scopus 로고    scopus 로고
    • Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus infected/acquired immunodeficiency syndrome (HIV/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: A combined study of two cohorts
    • 15765806 10.1080/13550280490521078
    • Cysique L, Maruff P, Brew B (2004) Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus infected/acquired immunodeficiency syndrome (HIV/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: a combined study of two cohorts. J Neurovirol 10:350-357
    • (2004) J Neurovirol , vol.10 , pp. 350-357
    • Cysique, L.1    Maruff, P.2    Brew, B.3
  • 6
    • 68249156652 scopus 로고    scopus 로고
    • Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy
    • 10.1212/WNL.0b013e3181ab2b3b 1:STN:280:DC%2BD1MrjtVOnug%3D%3D 19474412 10.1212/WNL.0b013e3181ab2b3b
    • Cysique LA, Vaida F, Letendre S, Gibson S, Cherner M, Woods SP et al (2009) Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy. Neurology 73:342-348. doi: 10.1212/WNL.0b013e3181ab2b3b
    • (2009) Neurology , vol.73 , pp. 342-348
    • Cysique, L.A.1    Vaida, F.2    Letendre, S.3    Gibson, S.4    Cherner, M.5    Woods, S.P.6
  • 8
    • 0042830227 scopus 로고    scopus 로고
    • Delayed central nervous system virus suppression during highly active antiretroviral therapy is associated with HIV encephalopathy, but not with viral drug resistance or poor central nervous system drug penetration
    • 12960822 10.1097/00002030-200309050-00008
    • Eggers C, Hertogs K, Sturenburg HJ, van Lunzen J, Stellbrink HJ (2003) Delayed central nervous system virus suppression during highly active antiretroviral therapy is associated with HIV encephalopathy, but not with viral drug resistance or poor central nervous system drug penetration. AIDS 17:1897-1906
    • (2003) AIDS , vol.17 , pp. 1897-1906
    • Eggers, C.1    Hertogs, K.2    Sturenburg, H.J.3    Van Lunzen, J.4    Stellbrink, H.J.5
  • 10
    • 0034701034 scopus 로고    scopus 로고
    • Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources
    • 1:STN:280:DC%2BD3c7lt1yntQ%3D%3D 10690988 10.1212/WNL.54.4.927
    • Ellis RJ, Gamst AC, Capparelli E, Spector SA, Hsia K, Wolfson T et al (2000) Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology 54:927-936
    • (2000) Neurology , vol.54 , pp. 927-936
    • Ellis, R.J.1    Gamst, A.C.2    Capparelli, E.3    Spector, S.A.4    Hsia, K.5    Wolfson, T.6
  • 11
    • 0036279512 scopus 로고    scopus 로고
    • Progression to neuropsychological impairment in human immunodeficiency virus infection predicted by elevated cerebrospinal fluid levels of human immunodeficiency virus RNA
    • 12056927 10.1001/archneur.59.6.923
    • Ellis RJ, Moore DJ, Childers ME, Letendre S, McCutchan JA, Wolfson T et al (2002) Progression to neuropsychological impairment in human immunodeficiency virus infection predicted by elevated cerebrospinal fluid levels of human immunodeficiency virus RNA. Arch Neurol 59:923-928
    • (2002) Arch Neurol , vol.59 , pp. 923-928
    • Ellis, R.J.1    Moore, D.J.2    Childers, M.E.3    Letendre, S.4    McCutchan, J.A.5    Wolfson, T.6
  • 12
    • 33645101488 scopus 로고    scopus 로고
    • Neuroactive antiretroviral drugs do not influence neurocognitive performance in less advanced HIV-infected patients responding to highly active antiretroviral therapy
    • 16540934 10.1097/01.qai.0000197077.64021.07
    • Giancola ML, Lorenzini P, Balestra P, Larussa D, Baldini F, Corpolongo A et al (2006) Neuroactive antiretroviral drugs do not influence neurocognitive performance in less advanced HIV-infected patients responding to highly active antiretroviral therapy. J Acquir Immune Defic Syndr 41:332-337
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 332-337
    • Giancola, M.L.1    Lorenzini, P.2    Balestra, P.3    Larussa, D.4    Baldini, F.5    Corpolongo, A.6
  • 13
    • 79952921819 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: Differences in rates, nature, and predictors
    • 1:CAS:528:DC%2BC3MXisVyrtb8%3D 3032197 21174240 10.1007/s13365-010-0006-1
    • Heaton RK, Franklin DR, Ellis RJ, McCutchan JA, Letendre SL, Leblanc S et al (2011) HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol 17:3-16
    • (2011) J Neurovirol , vol.17 , pp. 3-16
    • Heaton, R.K.1    Franklin, D.R.2    Ellis, R.J.3    McCutchan, J.A.4    Letendre, S.L.5    Leblanc, S.6
  • 14
  • 15
    • 84859230231 scopus 로고    scopus 로고
    • Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder
    • 22156215
    • Letendre S (2011) Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder. Top Antivir Med 19:137-42
    • (2011) Top Antivir Med , vol.19 , pp. 137-142
    • Letendre, S.1
  • 16
    • 84878838660 scopus 로고    scopus 로고
    • Persistent HIV in the central nervous system during treatment is associated with worse ART penetration and cognitive impairment
    • February 8-11; Montreal, Canada
    • Letendre S, McClernon D, Ellis R, et al. (2009). Persistent HIV in the central nervous system during treatment is associated with worse ART penetration and cognitive impairment. [Abstract 484b.] 16th Conference on Retroviruses and Opportunistic Infections (CROI). February 8-11; Montreal, Canada.
    • (2009) 16th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Letendre, S.1    McClernon, D.2    Ellis, R.3
  • 17
    • 78751572944 scopus 로고    scopus 로고
    • Protease inhibitor monotherapy
    • 10.1097/QCO.0b013e3283422cdf 1:CAS:528:DC%2BC3cXhs1WjsL3J 10.1097/QCO.0b013e3283422cdf
    • Perez-Valero I, Arribas JR (2011) Protease inhibitor monotherapy. Curr Op Infect Dis 24:7-11. doi: 10.1097/QCO.0b013e3283422cdf
    • (2011) Curr Op Infect Dis , vol.24 , pp. 7-11
    • Perez-Valero, I.1    Arribas, J.R.2
  • 18
    • 1542345594 scopus 로고    scopus 로고
    • Antiretroviral drug treatment interruption in human immunodeficiency virus infected adults: Clinical and pathogenetic implications for the central nervous system
    • 1:CAS:528:DC%2BD2cXhsFajtrc%3D 14982739
    • Price RW, Deeks SG (2004) Antiretroviral drug treatment interruption in human immunodeficiency virus infected adults: clinical and pathogenetic implications for the central nervous system. J Neurovirol 10(Suppl 1):44-51
    • (2004) J Neurovirol , vol.10 , Issue.SUPPL. 1 , pp. 44-51
    • Price, R.W.1    Deeks, S.G.2
  • 19
    • 34548208844 scopus 로고    scopus 로고
    • The prevalence and incidence of neurocognitive impairment in the HAART era
    • 17721099 10.1097/QAD.0b013e32828e4e27
    • Robertson KR, Smurzynski M, Parsons T, Wu K, Bosch R, Wu J et al (2007) The prevalence and incidence of neurocognitive impairment in the HAART era. AIDS 21:1915-1921
    • (2007) AIDS , vol.21 , pp. 1915-1921
    • Robertson, K.R.1    Smurzynski, M.2    Parsons, T.3    Wu, K.4    Bosch, R.5    Wu, J.6
  • 20
    • 0036091705 scopus 로고    scopus 로고
    • HIV-associated cognitive impairment before and after the advent of combination therapy
    • 11935465 10.1080/13550280290049615
    • Sacktor N, McDermott M, Marder K, Schifitto G, Selnes OA, McArthur JC et al (2002) HIV-associated cognitive impairment before and after the advent of combination therapy. J Neurovirol 8:136-142
    • (2002) J Neurovirol , vol.8 , pp. 136-142
    • Sacktor, N.1    McDermott, M.2    Marder, K.3    Schifitto, G.4    Selnes, O.A.5    McArthur, J.C.6
  • 21
    • 77952938752 scopus 로고    scopus 로고
    • Cognitive dysfunction in HIV patients despite long-standing suppression of viremia
    • 10.1097/QAD.0b013e3283354a7b 19996937
    • Simioni S, Cavassini M, Annoni JM, Rimbault Abraham A, Bourquin I, Schiffer V et al (2010) Cognitive dysfunction in HIV patients despite long-standing suppression of viremia. AIDS 24:1243-1250. doi: 10.1097/QAD.0b013e3283354a7b
    • (2010) AIDS , vol.24 , pp. 1243-1250
    • Simioni, S.1    Cavassini, M.2    Annoni, J.M.3    Rimbault Abraham, A.4    Bourquin, I.5    Schiffer, V.6
  • 22
    • 79551604850 scopus 로고    scopus 로고
    • Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort
    • 10.1097/QAD.0b013e32834171f8 3022370 21124201 10.1097/QAD. 0b013e32834171f8
    • Smurzynski M, Wu K, Letendre S, Robertson K, Bosch RJ, Clifford DB et al (2011) Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort. AIDS 25:357-365. doi: 10.1097/QAD. 0b013e32834171f8
    • (2011) AIDS , vol.25 , pp. 357-365
    • Smurzynski, M.1    Wu, K.2    Letendre, S.3    Robertson, K.4    Bosch, R.J.5    Clifford, D.B.6
  • 23
    • 84855615123 scopus 로고    scopus 로고
    • HIV-1 viral encephalitis after development of viral resistance to plasma suppressive antiretroviral therapy
    • 10.1089/AID.2011.0020 10.1089/aid.2011.0020
    • Tamarit MDP, Quereda C, Gonzalez-Rozas M, Corral I, Casado JL (2012) HIV-1 viral encephalitis after development of viral resistance to plasma suppressive antiretroviral therapy. AIDS Res Hum Retroviruses 28:83-86. doi: 10.1089/AID.2011.0020
    • (2012) AIDS Res Hum Retroviruses , vol.28 , pp. 83-86
    • Tamarit, M.D.P.1    Quereda, C.2    Gonzalez-Rozas, M.3    Corral, I.4    Casado, J.L.5
  • 24
    • 34249895916 scopus 로고    scopus 로고
    • Persistence of neuropsychological deficits despite long-term HAART in patients with HIV-related neurocognitive impairment. Prevalence and risk factors
    • 17356465 10.1097/QAI.0b013e318042e1ee
    • Tozzi V, Balestra P, Bellagamba R, Corpolongo A, Salvatori MF, Visco-Comandini U et al (2007) Persistence of neuropsychological deficits despite long-term HAART in patients with HIV-related neurocognitive impairment. Prevalence and risk factors. J Acquir Immune Defic Syndr 45:174-182
    • (2007) J Acquir Immune Defic Syndr. , vol.45 , pp. 174-182
    • Tozzi, V.1    Balestra, P.2    Bellagamba, R.3    Corpolongo, A.4    Salvatori, M.F.5    Visco-Comandini, U.6
  • 25
    • 2342595777 scopus 로고    scopus 로고
    • Neurocognitive impairment influences quality of life in HIV-infected patients receiving HAART
    • 1:STN:280:DC%2BD2c7otV2nug%3D%3D 15075020 10.1258/095646204773557794
    • Tozzi V, Balestra P, Murri R, Galgani S, Bellagamba R, Narciso P et al (2004) Neurocognitive impairment influences quality of life in HIV-infected patients receiving HAART. Int J STD AIDS 15:254-259
    • (2004) Int J STD AIDS , vol.15 , pp. 254-259
    • Tozzi, V.1    Balestra, P.2    Murri, R.3    Galgani, S.4    Bellagamba, R.5    Narciso, P.6
  • 26
    • 69549110328 scopus 로고    scopus 로고
    • Changes in cognition during antiretroviral therapy: Comparison of 2 different ranking systems to measure antiretroviral drug efficacy on HIV-associated neurocognitive disorders
    • 1:CAS:528:DC%2BD1MXhtVektbjP 19731418 10.1097/QAI.0b013e3181af83d6
    • Tozzi V, Balestra P, Salvatori MF, Vlassi C, Liuzzi G, Giancola ML et al (2009) Changes in cognition during antiretroviral therapy: comparison of 2 different ranking systems to measure antiretroviral drug efficacy on HIV-associated neurocognitive disorders. J Acquir Immune Defic Syndr 52:56-63
    • (2009) J Acquir Immune Defic Syndr , vol.52 , pp. 56-63
    • Tozzi, V.1    Balestra, P.2    Salvatori, M.F.3    Vlassi, C.4    Liuzzi, G.5    Giancola, M.L.6
  • 27
    • 66749103433 scopus 로고    scopus 로고
    • The transport of anti-HIV drugs across blood-CNS interfaces: Summary of current knowledge and recommendations for further research
    • 10.1016/j.antiviral.2008.12.013 10.1016/j.antiviral.2008.12.013
    • Varatharajan L, Thomas SA (2009) The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research. Antiviral Res 82:99-109. doi: 10.1016/j.antiviral.2008.12.013
    • (2009) Antiviral Res , vol.82 , pp. 99-109
    • Varatharajan, L.1    Thomas, S.A.2
  • 28
    • 33750937199 scopus 로고    scopus 로고
    • Cerebrospinal fluid viral loads reach less than 2 copies/ml in HIV-1-infected patients with effective antiretroviral therapy
    • 1:CAS:528:DC%2BD28Xhtlajs7zP 17302245
    • Yilmaz A, Svennerholm B, Hagberg L, Gisslen M (2006) Cerebrospinal fluid viral loads reach less than 2 copies/ml in HIV-1-infected patients with effective antiretroviral therapy. Antivir Ther 11:833-837
    • (2006) Antivir Ther , vol.11 , pp. 833-837
    • Yilmaz, A.1    Svennerholm, B.2    Hagberg, L.3    Gisslen, M.4
  • 29
    • 0020527558 scopus 로고
    • The hospital anxiety and depression scale
    • 10.1111/j.1600-0447.1983.tb09716.x
    • Zigmond AS, Snaith RP (1984) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361-370
    • (1984) Acta Psychiatr Scand , vol.67 , pp. 361-370
    • Zigmond, A.S.1    Snaith, R.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.