Comparing plasma concentrations of persistent organic pollutants and metals in primiparous women from northern and southern Canada

Science of the Total Environment

Volumn 479-480, Issue 1, 2014, Pages 306-318

  Curren, Meredith S ^a   Davis, Karelyn ^a   Liang, Chun Lei ^a   Adlard, Bryan ^a   Foster, Warren G ^b   Donaldson, Shawn G ^a   Kandola, Kami ^c   Brewster, Janet ^d   Potyrala, Mary ^d   Van Oostdam, Jay ^e  

^a Environmental Health Center   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c DEPARTMENT OF ENVIRONMENT AND NATURAL RESOURCES   (Canada)

^d Government of Nunavut   (Canada)

^e NONE

Author keywords

Arctic; Biomonitoring; Inuit; Persistent organic pollutants; Pregnancy; Primiparous

Indexed keywords

ARCTIC; BIOMONITORING; INUIT; PERSISTENT ORGANIC POLLUTANT (POP); PREGNANCY; PRIMIPAROUS;

BLOOD; LIPIDS; MERCURY (METAL); POPULATION STATISTICS;

ORGANIC POLLUTANTS;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 2,2',4,4',5,5' HEXABROMODIPHENYL ETHER; 2,2',4,4',5,5' HEXACHLOROBIPHENYL; BETA HEXACHLOROCYCLOHEXANE; CADMIUM; CHLORPHENOTANE; LEAD; MERCURY; METAL; NONACHLOR; OXYCHLORDANE; PBDE 47; PCB 118; PCB 138; PCB 180; POLYBROMINATED DIPHENYL ETHER; POLYCHLORINATED BIPHENYL; SELENIUM; UNCLASSIFIED DRUG;

BIOMONITORING; CONCENTRATION (COMPOSITION); HEALTH IMPACT; INDIGENOUS POPULATION; LIPID; METAL; ORGANIC POLLUTANT; PBDE; PLASMA; POLLUTION EFFECT; POLLUTION EXPOSURE; PREGNANCY; WOMENS HEALTH;

ABORIGINE; ADOLESCENT; ADULT; ARCTIC; ARTICLE; BIOLOGICAL MONITORING; BIRTHPLACE; BLOOD LEVEL; CANADA; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); ENVIRONMENTAL EXPOSURE; ESKIMO; ETHNIC DIFFERENCE; FEMALE; GEOGRAPHIC DISTRIBUTION; GEOMETRIC MEAN CONCENTRATION; HUMAN; IMMIGRANT; MATERNAL AGE; PERSISTENT ORGANIC POLLUTANT; POLLUTANT; PRIMIPARA; PRIORITY JOURNAL; YOUNG ADULT;

ALBERTA; BRITISH COLUMBIA; CALGARY; CANADA; HALIFAX; HAMILTON [ONTARIO]; NOVA SCOTIA; ONTARIO [CANADA]; OTTAWA; VANCOUVER [BRITISH COLUMBIA];

ARCTIC; BIOMONITORING; INUIT; PERSISTENT ORGANIC POLLUTANTS; PREGNANCY; PRIMIPAROUS;

ADULT; CANADA; DICHLORODIPHENYL DICHLOROETHYLENE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; LINDANE; MATERNAL EXPOSURE; METALS; PARITY; PREGNANCY;

EID: 84896716995     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2014.01.017     Document Type: Article

References (57)

1. Arbuckle T.E., Kubwabo C., Walker M., Davis K., Lalonde K., Kosarac I., et al. Umbilical cord blood levels of perfluoroalkyl acids and polybrominated flame retardants. Int J Hyg Environ Health 2013, 216(2):184-194.
2. Armstrong B., Tofflemire K., Myles E., Receveur O., Chan L. Monitoring temporal trends of human environmental contaminants in the NWT study 2007, Department of Health and Social Services, Government of the Northwest Territories.
3. Bernert J.T., Turner W.E., Patterson D.G., Needham L.L. Calculation of serum "total lipid" concentrations for the adjustment of persistent organohalogen toxicant measurements in human samples. Chemosphere 2007, 68(5):824-831.
4. Birnbaum L.S., Staskal D.F. Brominated flame retardants: cause for concern?. Environ Health Perspect 2004, 112(1):9-17.
5. Boucher O., Bastien C.H., Saint-Amour D., Dewailly É., Ayotte P., Jacobson J.L., et al. Prenatal exposure to methylmercury and PCBs affects distinct stages of information processing: an event-related potential study with Inuit children. Neurotoxicology 2010, 31(4):373-384.
6. Boucher O., Burden M.J., Muckle G., Saint-Amour D., Ayotte P., Dewailly É., et al. Response inhibition and error monitoring during a visual go/no-go task in Inuit children exposed to lead, polychlorinated biphenyls, and methylmercury. Environ Health Perspect 2012, 120(4):608-615.
7. Boucher O., Jacobson S.W., Plusquellec P., Dewailly É., Ayotte P., Forget-Dubois N., et al. Prenatal methylmercury, postnatal lead exposure, and evidence of attention deficit/hyperactivity disorder among Inuit children in Arctic Québec. Environ Health Perspect 2012, 120(10):1456-1461.
8. Butler Walker J., Seddon L., McMullen E., Houseman J., Tofflemire K., Corriveau A., et al. Organochlorine levels in maternal and umbilical cord blood plasma in Arctic Canada. Sci Total Environ 2003, 302(1-3):27-52.
9. Butler Walker J., Houseman J., Seddon L., McMullen E., Tofflemire K., Mills C., et al. Maternal and umbilical cord blood levels of mercury, lead, cadmium, and essential trace elements in Arctic Canada. Environ Res 2006, 100(3):295-318.
10. CEC Trinational biomonitoring study: assessment of persistent organic pollutants and selected metals in the blood of first-birth mothers in southern Canada and Mexico and in women of reproductive age in the United States 2011, Commission for Environmental Cooperation, Montreal, [Available: http://www.cec.org/Storage/128/15294_QA08.34-CEC-Trinational-Biomonitoring_en.pdf (accessed 12 July 2012)].
11. Channa K., Röllin H.B., Nøst T.H., Odland J.Ö., Sandanger T.M. Prenatal exposure to DDT in malaria endemic region following indoor residual spraying and in non-malaria coastal regions of South Africa. Sci Total Environ 2012, 429:183-190.
12. Dallaire F., Dewailly É., Vézina C., Muckle G., Weber J., Bruneau S., et al. Effect of prenatal exposure to polychlorinated biphenyls on incidence of acute respiratory infections in preschool Inuit children. Environ Health Perspect 2006, 114(8):1301-1305.
13. Dallaire R., Ayotte P., Pereg D., Déry S., Dumas P., Langlois É., et al. Determinants of plasma concentrations of perfluorooctanesulfonate and brominated organic compounds in Nunavik Inuit adults. Environ Sci Tech 2009, 43(13):5130-5136.
14. Darnerud P.O. Toxic effects of brominated flame retardants in man and in wildlife. Environ Int 2003, 29(6):841-853.
15. Dewailly É., Weihe P. The effects of Arctic pollution on population health. AMAP Assessment 2002: human health in the Arctic 2003, 95-105. Arctic Monitoring and Assessment Program, Oslo. S.J. Wilson, C. Symon (Eds.).
16. Dewailly É., Levesque B., Duchesne J., Dumas P., Scheuhammer A., Gariepy C., et al. Lead shot as a source of lead poisoning in the Canadian Arctic. Epidemiology 2000, 11(4):S146.
17. Dewailly É., Ayotte P., Bruneau S., Gingras S., Belles-Isles M., Roy R. Susceptibility to infections and immune status in Inuit infants exposed to organochlorines. Environ Health Perspect 2000, 108(3):205-211.
18. Dewailly É., Dallaire R., Pereg D., Ayotte P., Fontaine J., Déry S. Nunavik Inuit Health Survey 2004. Qanuippitaa? How are we? Exposure to environmental contaminants in Nunavik: persistent organic pollutants and new contaminants of concern 2007, Insititute national de santé publique du Québec (INSPQ) and Nunavik Regional Board of Health and Social Services, [(Printed), ISBN: 978-2-550-51995-3 (PDF)].
19. Donaldson S.G., Van Oostdam J., Tikhonov C., Feeley M., Armstrong B., Ayotte P., et al. Environmental contaminants and human health in the Canadian Arctic. Sci Total Environ 2010, 408(22):5165-5234.
20. Eskenazi B., Fenster L., Castorina R., Marks A.R., Sjödin A., Rosas L.G., et al. A comparison of PBDE serum concentrations in Mexican and Mexican-American children living in California. Environ Health Perspect 2011, 119(10):1442-1448.
21. Ethier A., Muckle G., Bastien C., Dewailly É., Ayotte P., Arfken C., et al. Effects of environmental contaminant exposure on visual brain development: a prospective electrophysiological study in school-aged children. Neurotoxicology 2012, 33(5):1075-1085.
22. Foster W.G., Cheung A.P., Davis K., Graves G., Jarrell J., Leblanc A., et al. Circulating metals and persistent organic pollutant concentrations in Canadian and non-Canadian born primiparous women from five Canadian centres: results of a pilot biomonitoring study. Sci Total Environ 2012, 435-436:326-336.
23. Frederiksen M., Thomsen C., Frøshaug M., Vorkamp K., Thomsen M., Becher G., et al. Polybrominated diphenyl ethers in paired samples of maternal and umbilical cord blood plasma and associations with house dust in a Danish cohort. Int J Hyg Environ Health 2010, 213(4):233-242.
24. Gilman A., Ayotte P., Berner J., Dewailly É., Dudarev A., Bonefeld-Jorgensen E., et al. Public health and the effects of contaminants. AMAP Assessment 2009: human health in the Arctic 2009, 143-190. Arctic Monitoring and Assessment Program, Oslo. S.J. Wilson, C. Symon (Eds.).
25. Haines D.A., Murray J. Human biomonitoring of environmental chemicals - early results of the 2007-2009 Canadian Health Measures Survey for males and females. Int J Hyg Environ Health 2012, 215(2):133-137.
26. Hansen J.C., Gilman A., Klopov V., Odland J.O. Pollution and human health. AMAP Assessment Report: Arctic pollution issues 1998, 775-844. Arctic Monitoring and Assessment Program, Oslo. S.J. Wilson, J.L. Murray, H.P. Huntington (Eds.).
27. Health Canada Report on human biomonitoring of environmental chemicals: results of the Canadian Health Measures Survey Cycle 1 (2007-2009) 2010, Health Canada, Ottawa, [Available: www.healthcanada.gc.ca (accessed 12 July 2012)].
28. Health Canada Second report on human biomonitoring of environmental chemicals in Canada 2013, Health Canada, Ottawa, [Available: www.healthcanada.gc.ca (accessed 20 April 2013)].
29. Johnson-Restrepo B., Kannan K. An assessment of sources and pathways of human exposure to polybrominated diphenyl ethers in the United States. Chemosphere 2009, 76(4):542-548.
30. Jones-Otazo H.A., Clarke J.P., Diamond M.L., Archbold J.A., Ferguson G., Harner T., et al. Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs. Environ Sci Tech 2005, 39(14):5121-5130.
31. Kiciński M., Viaene M.K., Den Hond E., Schoeters G., Covaci A., Dirtu A.C., et al. Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents: a cross-sectional study. Environ Health 2012, 11(1).
32. Kirk J.L., Lehnherr I., Andersson M., Braune B.M., Chan L., Dastoor A.P., et al. Mercury in Arctic marine ecosystems: sources, pathways and exposure. Environ Res 2012, 119:64-87.
33. Kuhnlein H.V., Receveur O., Chan H.M., Loring E. Assessment of dietary benefit/risk in Inuit communities 2000, Center for Indigenous Peoples' Nutrition and Environment (CINE), McGill University, Montreal, Québec, Canada.
34. Kutner M.H., Nachtsheim C.J., Neter J., Li W. Applied linear statistical models 2005, McGraw-Hill Irwin, Boston. 5th ed.
35. Lee D., Steffes M.W., Sjödin A., Jones R.S., Needham L.L., Jacobs D.R. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. PLoS One 2011, 6(1).
36. Lévesque B., Duchesne J., Gariépy C., Rhainds M., Dumas P., Scheuhammer A.M., et al. Monitoring of umbilical cord blood lead levels and sources assessment among the Inuit. Occup Environ Med 2003, 60(9):693-695.
37. Longnecker M.P., Klebanoff M.A., Gladen B.C., Berendes H.W. Serial levels of serum organochlorines during pregnancy and postpartum. Arch Environ Health 1999, 54(2):110-114.
38. Lorber M. Exposure of Americans to polybrominated diphenyl ethers. J Expo Sci Environ Epidemiol 2008, 18(1):2-19.
39. Muckle G., Ayotte P., Dewailly É., Jacobson S.W., Jacobson J.L. Determinants of polychlorinated biphenyls and methylmercury exposure in Inuit women of childbearing age. Environ Health Perspect 2001, 109(9):957-963.
40. Muennig P., Song X., Payne-Sturges D.C., Gee G.C. Blood and urine levels of long half-life toxicants by nativity among immigrants to the United States. Sci Total Environ 2011, 412-413:109-113.
41. Potyrala M., Brewster J., Tofflemire K., Receveur O., Chan H.M., Sobol I. The Anaana Project (Inuit prenatal health survey) 2008, Department of Health and Social Services, Government of Nunavut.
42. R Core Development Team R: a language and environment for statistical computing 2011, R Foundation for Statistical Computing, Vienna, [Available: http://www.R-project.org].
43. Ruzzin J., Petersen R., Meugnier E., Madsen L., Lock E., Lillefosse H., et al. Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 2010, 118(4):465-471.
44. Ryan J.J., Van Oostdam J. Polybrominated diphenyl ethers (PBDEs) in maternal and cord plasma of several northern Canadian populations. Organohalogen Compd 2004, 66:2579-2585.
45. Sandanger T.M., Sinotte M., Dumas P., Marchand M., Sandau C.D., Pereg D., et al. Plasma concentrations of selected organobromine compounds and polychlorinated biphenyls in postmenopausal women of Québec, Canada. Environ Health Perspect 2007, 115(10):1429-1434.
46. Siddique S., Xian Q., Abdelouahab N., Takser L., Phillips S.P., Feng Y., et al. Levels of dechlorane plus and polybrominated diphenylethers in human milk in two Canadian cities. Environ Int 2012, 39(1):50-55.
47. Statistics Canada Canadian Health Measures Survey user guide Available:, [accessed 31 August 2012]. http://www.statcan.gc.ca/imdb-bmdi/document/5071_D2_T1_V1-eng.pdf.
48. Stern A.H. A revised probabilistic estimate of the maternal methyl mercury intake dose corresponding to a measured cord blood mercury concentration. Environ Health Perspect 2005, 113(2):155-163.
49. Tomy G.T., Pleskach K., Ferguson S.H., Hare J., Stern G., Macinnis G., et al. Trophodynamics of some PFCs and BFRs in a western Canadian Arctic marine food web. Environ Sci Tech 2009, 43(11):4076-4081.
50. Tsuji L.J.S., Wainman B.C., Martin I.D., Weber J., Sutherland C., Nieboer E. Abandoned mid-Canada radar line sites in the Western James region of northern Ontario, Canada: a source of organochlorines for First Nations people?. Sci Total Environ 2006, 370(2-3):452-466.
51. Turunen A.W., Jula A., Suominen A.L., Männistö S., Marniemi J., Kiviranta H., et al. Fish consumption, omega-3 fatty acids, and environmental contaminants in relation to low-grade inflammation and early atherosclerosis. Environ Res 2013, 120:43-54.
52. Valera B., Muckle G., Poirier P., Jacobson S.W., Jacobson J.L., Dewailly É. Cardiac autonomic activity and blood pressure among Inuit children exposed to mercury. Neurotoxicology 2012, 33(5):1067-1074.
53. Valera B., Dewailly É., Poirier P. Association between methylmercury and cardiovascular risk factors in a native population of Quebec (Canada): a retrospective evaluation. Environ Res 2013, 120:102-108.
54. Van Oostdam J., Donaldson S.G., Feeley M., Arnold D., Ayotte P., Bondy G., et al. Human health implications of environmental contaminants in Arctic Canada: a review. Sci Total Environ 2005, 351-352:165-246.
55. Westgard J.O. Basic QC practices: training in statistical quality control for health care laboratories. 2002, Madison, WI: Westgard QC, Inc.
56. Woodruff T.J., Zota A.R., Schwartz J.M. Environmental chemicals in pregnant women in the United States: NHANES 2003-2004. Environ Health Perspect 2011, 119(6):878-885.
57. Yaginuma-Sakurai K., Murata K., Iwai-Shimada M., Nakai K., Kurokawa N., Tatsuta N., et al. Hair-to-blood ratio and biological half-life of mercury: experimental study of methylmercury exposure through fish consumption in humans. J Toxicol Sci 2012, 37(1):123-130.