Zyflamend, a polyherbal mixture, down regulates class I and class II histone deacetylases and increases p21 levels in castrate-resistant prostate cancer cells

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Huang, E Chu ^a   Zhao, Yi ^a   Chen, Guoxun ^a   Baek, Seung J ^a   McEntee, Michael F ^a   Minkin, Steven ^a   Biggerstaff, John P ^a   Whelan, Jay ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Castrate resistant; CBP p300; CWR22Rv1; Epigenetic; HDAC; Herbs; Histone acetyltransferase; Histone deacetylase; p21; Prostate cancer; Zyflamend

Indexed keywords

ANTINEOPLASTIC AGENT; BERBERIS VULGARIS EXTRACT; CAMELLIA SINENSIS EXTRACT; CBP PROTEIN; COPTIS CHINENSIS EXTRACT; CURCUMA LONGA EXTRACT; E1A ASSOCIATED P300 PROTEIN; GINGER EXTRACT; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OCIMUM SANCTUM EXTRACT; ORIGANUM VULGAR EXTRACT; PLANT EXTRACT; POLYGONUM CUSPIDATUM EXTRACT; PROTEIN; PROTEIN P21; ROSMARINUS OFFICINALIS EXTRACT; SCUTELLARIA BAICALENSIS EXTRACT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ZYFLAMEND; HISTONE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BARBERRY; BASIL SKULLCAP; CANCER CELL; CANCER CELL CULTURE; CASTRATION RESISTANT PROSTATE CANCER; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; COPTIS CHINENSIS; DNA SYNTHESIS; DOWN REGULATION; GENE SILENCING; GINGER; GROWTH INHIBITION; HISTONE ACETYLATION; HU ZHANG; HUMAN; HUMAN CELL; MALE; MEDICINAL PLANT; OCIMUM TENUIFLORUM; OREGANO; PROTEIN EXPRESSION; ROSEMARY; TEA; TUMOR SUPPRESSOR GENE; UPREGULATION; WESTERN BLOTTING; ACETYLATION; CELL CYCLE; COPTIS; DRUG EFFECTS; GENETICS; METABOLISM; PHYTOTHERAPY; PROSTATIC NEOPLASMS; SCUTELLARIA; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ACETYLATION; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COPTIS; DOWN-REGULATION; HISTONE DEACETYLASES; HISTONES; HUMANS; MALE; P300-CBP TRANSCRIPTION FACTORS; PHYTOTHERAPY; PLANT EXTRACTS; PROSTATIC NEOPLASMS; RNA, SMALL INTERFERING; SCUTELLARIA; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84896716719     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-68     Document Type: Article

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