Tumor targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide

Biomaterials

Volumn 35, Issue 13, 2014, Pages 4082-4087

  Fei, Likun ^a   Yap, Li Peng ^b   Conti, Peter S ^b   Shen, Wei Chiang ^a   Zaro, Jennica L ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Drug delivery; Image analysis; Peptide; PH sensitive activation; Recombinant protein

Indexed keywords

CELL PENETRATING PEPTIDES (CPPS); CELL-PENETRATING PEPTIDE; GLUTATHIONE-S-TRANSFERASE; INTRACELLULAR DELIVERY; MACROMOLECULAR THERAPEUTICS; PH SENSITIVE; THERAPEUTIC POTENTIALS; TUMOR MICROENVIRONMENT;

AMINO ACIDS; CELLS; CYTOLOGY; DRUG DELIVERY; ENZYME ACTIVITY; IMAGE ANALYSIS; MEDICAL IMAGING; RECOMBINANT PROTEINS; TUMORS;

PEPTIDES;

CELL PENETRATING PEPTIDE; GLUTATHIONE TRANSFERASE; HISTIDINE GLUTAMATE CO OLIGOPEPTIDE; HYBRID PROTEIN; IODINE 125; MODEL AMPHIPATHIC PEPTIDE; OLIGOPEPTIDE; PEPTIDE; UNCLASSIFIED DRUG; GLUTAMIC ACID; HISTIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST ADENOCARCINOMA; CANCER GROWTH; COMPARATIVE STUDY; CONTROLLED STUDY; DNA SEQUENCE; DRUG DELIVERY SYSTEM; EX VIVO STUDY; HELA CELL; HUMAN; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; XENOGRAFT; ANIMAL; BREAST NEOPLASMS; CELL LINE; CHEMISTRY; DRUG SCREENING; FEMALE; HELA CELL LINE; PROCEDURES; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL-PENETRATING PEPTIDES; DRUG DELIVERY SYSTEMS; FEMALE; GLUTAMIC ACID; GLUTATHIONE TRANSFERASE; HELA CELLS; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896705839     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.01.047     Document Type: Article

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