-
1
-
-
77953257877
-
Passive and active drug targeting: drug delivery to tumors as an example
-
Torchilin V.P. Passive and active drug targeting: drug delivery to tumors as an example. Handb Exp Pharmacol 2010, 197:3-53.
-
(2010)
Handb Exp Pharmacol
, vol.197
, pp. 3-53
-
-
Torchilin, V.P.1
-
2
-
-
33747840618
-
Polymer conjugates as anticancer nanomedicines
-
Duncan R. Polymer conjugates as anticancer nanomedicines. Nat Rev Cancer 2006, 6:688-701.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 688-701
-
-
Duncan, R.1
-
3
-
-
0041181628
-
HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action
-
Kopecek J., Kopeckova P., Minko T., Lu Z. HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action. Eur J Pharm Biopharm 2000, 50:61-81.
-
(2000)
Eur J Pharm Biopharm
, vol.50
, pp. 61-81
-
-
Kopecek, J.1
Kopeckova, P.2
Minko, T.3
Lu, Z.4
-
4
-
-
70349981387
-
Design and development of polymer conjugates as anti-angiogenic agents
-
Segal E., Satchi-Fainaro R. Design and development of polymer conjugates as anti-angiogenic agents. Adv Drug Deliv Rev 2009, 61:1159-1176.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1159-1176
-
-
Segal, E.1
Satchi-Fainaro, R.2
-
5
-
-
70349784954
-
Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate
-
Miller K., Erez R., Segal E., Shabat D., Satchi-Fainaro R. Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate. Angew Chem Int Ed Engl 2009, 48:2949-2954.
-
(2009)
Angew Chem Int Ed Engl
, vol.48
, pp. 2949-2954
-
-
Miller, K.1
Erez, R.2
Segal, E.3
Shabat, D.4
Satchi-Fainaro, R.5
-
6
-
-
70349633880
-
Multivalent display of quinic acid based ligands for targeting E-selectin expressing cells
-
Shamay Y., Paulin D., Ashkenasy G., David A. Multivalent display of quinic acid based ligands for targeting E-selectin expressing cells. J Med Chem 2009, 52:5906-5915.
-
(2009)
J Med Chem
, vol.52
, pp. 5906-5915
-
-
Shamay, Y.1
Paulin, D.2
Ashkenasy, G.3
David, A.4
-
7
-
-
70249141559
-
E-selectin binding peptide-polymer-drug conjugates and their selective cytotoxicity against vascular endothelial cells
-
Shamay Y., Paulin D., Ashkenasy G., David A. E-selectin binding peptide-polymer-drug conjugates and their selective cytotoxicity against vascular endothelial cells. Biomaterials 2009, 30:6460-6468.
-
(2009)
Biomaterials
, vol.30
, pp. 6460-6468
-
-
Shamay, Y.1
Paulin, D.2
Ashkenasy, G.3
David, A.4
-
8
-
-
0036781811
-
Ligand-targeted therapeutics in anticancer therapy
-
Allen T.M. Ligand-targeted therapeutics in anticancer therapy. Nat Rev Cancer 2002, 2:750-763.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 750-763
-
-
Allen, T.M.1
-
9
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986, 46:6387-6392.
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
10
-
-
0034141430
-
In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA
-
Schwarze S.R., Dowdy S.F. In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA. Trends Pharmacol Sci 2000, 21:45-48.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 45-48
-
-
Schwarze, S.R.1
Dowdy, S.F.2
-
11
-
-
0002034191
-
Cell-penetrating peptides
-
Lindgren M., Hallbrink M., Prochiantz A., Langel U. Cell-penetrating peptides. Trends Pharmacol Sci 2000, 21:99-103.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 99-103
-
-
Lindgren, M.1
Hallbrink, M.2
Prochiantz, A.3
Langel, U.4
-
12
-
-
0033520487
-
In vivo protein transduction: delivery of a biologically active protein into the mouse
-
Schwarze S.R., Ho A., Vocero-Akbani A., Dowdy S.F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 1999, 285:1569-1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
13
-
-
33747449811
-
PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo
-
Michl J., Scharf B., Schmidt A., Huynh C., Hannan R., von Gizycki H., et al. PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo. Int J Cancer 2006, 119:1577-1585.
-
(2006)
Int J Cancer
, vol.119
, pp. 1577-1585
-
-
Michl, J.1
Scharf, B.2
Schmidt, A.3
Huynh, C.4
Hannan, R.5
von Gizycki, H.6
-
14
-
-
11144229887
-
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
-
Jiang T., Olson E.S., Nguyen Q.T., Roy M., Jennings P.A., Tsien R.Y. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc Natl Acad Sci U S A 2004, 101:17867-17872.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 17867-17872
-
-
Jiang, T.1
Olson, E.S.2
Nguyen, Q.T.3
Roy, M.4
Jennings, P.A.5
Tsien, R.Y.6
-
15
-
-
75949098347
-
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer
-
Olson E.S., Aguilera T.A., Jiang T., Ellies L.G., Nguyen Q.T., Wong E.H., et al. In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer. Integr Biol 2009, 1:382-393.
-
(2009)
Integr Biol
, vol.1
, pp. 382-393
-
-
Olson, E.S.1
Aguilera, T.A.2
Jiang, T.3
Ellies, L.G.4
Nguyen, Q.T.5
Wong, E.H.6
-
16
-
-
77749254873
-
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
-
Nguyen Q.T., Olson E.S., Aguilera T.A., Jiang T., Scadeng M., Ellies L.G., et al. Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci U S A 2010, 107:4317-4322.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4317-4322
-
-
Nguyen, Q.T.1
Olson, E.S.2
Aguilera, T.A.3
Jiang, T.4
Scadeng, M.5
Ellies, L.G.6
-
17
-
-
33847671358
-
TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors
-
Sethuraman V.A., Bae Y.H. TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors. J Control Release 2007, 118:216-224.
-
(2007)
J Control Release
, vol.118
, pp. 216-224
-
-
Sethuraman, V.A.1
Bae, Y.H.2
-
18
-
-
33947707837
-
Design, synthesis, and characterization of pH-sensitive PEG-PE conjugates for stimuli-sensitive pharmaceutical nanocarriers: the effect of substitutes at the hydrazone linkage on the ph stability of PEG-PE conjugates
-
Kale A.A., Torchilin V.P. Design, synthesis, and characterization of pH-sensitive PEG-PE conjugates for stimuli-sensitive pharmaceutical nanocarriers: the effect of substitutes at the hydrazone linkage on the ph stability of PEG-PE conjugates. Bioconjug Chem 2007, 18:363-370.
-
(2007)
Bioconjug Chem
, vol.18
, pp. 363-370
-
-
Kale, A.A.1
Torchilin, V.P.2
-
20
-
-
34249994393
-
Photobiological and thermal effects of photoactivating UVA light doses on cell cultures
-
Forman J., Dietrich M., Monroe W.T. Photobiological and thermal effects of photoactivating UVA light doses on cell cultures. Photochem Photobiol Sci 2007, 6:649-658.
-
(2007)
Photochem Photobiol Sci
, vol.6
, pp. 649-658
-
-
Forman, J.1
Dietrich, M.2
Monroe, W.T.3
-
21
-
-
0031455584
-
N-Nmoc-l-glutamate, a new caged glutamate with high chemical stability and low pre-photolysis activity
-
Rossi F.M., Margulis M., Tang C.M., Kao J.P. N-Nmoc-l-glutamate, a new caged glutamate with high chemical stability and low pre-photolysis activity. J Biol Chem 1997, 272:32933-32939.
-
(1997)
J Biol Chem
, vol.272
, pp. 32933-32939
-
-
Rossi, F.M.1
Margulis, M.2
Tang, C.M.3
Kao, J.P.4
-
22
-
-
78249248933
-
Light-induced peptide replication controls logic operations in small networks
-
Dadon Z., Samiappan M., Safranchik E.Y., Ashkenasy G. Light-induced peptide replication controls logic operations in small networks. Chem Eur J 2010, 16:12096-12099.
-
(2010)
Chem Eur J
, vol.16
, pp. 12096-12099
-
-
Dadon, Z.1
Samiappan, M.2
Safranchik, E.Y.3
Ashkenasy, G.4
-
23
-
-
0034093145
-
Measurement of nucleotide exchange rate constants in single rabbit soleus myofibrils during shortening and lengthening using a fluorescent ATP analog
-
Shirakawa I., Chaen S., Bagshaw C.R., Sugi H. Measurement of nucleotide exchange rate constants in single rabbit soleus myofibrils during shortening and lengthening using a fluorescent ATP analog. Biophys J 2000, 78:918-926.
-
(2000)
Biophys J
, vol.78
, pp. 918-926
-
-
Shirakawa, I.1
Chaen, S.2
Bagshaw, C.R.3
Sugi, H.4
-
24
-
-
0037421039
-
Caged RNase: photoactivation of the enzyme from perfect off-state by site-specific incorporation of 2-nitrobenzyl moiety
-
Hiraoka T., Hamachi I. Caged RNase: photoactivation of the enzyme from perfect off-state by site-specific incorporation of 2-nitrobenzyl moiety. Bioorg Med Chem Lett 2003, 13:13-15.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 13-15
-
-
Hiraoka, T.1
Hamachi, I.2
-
25
-
-
0036691226
-
Synthesis and biochemical properties of a new photoactivatable cholesterol analog 7,7-azocholestanol and its linoleate ester in Chinese hamster ovary cell lines
-
Cruz J.C., Thomas M., Wong E., Ohgami N., Sugii S., Curphey T., et al. Synthesis and biochemical properties of a new photoactivatable cholesterol analog 7,7-azocholestanol and its linoleate ester in Chinese hamster ovary cell lines. J Lipid Res 2002, 43:1341-1347.
-
(2002)
J Lipid Res
, vol.43
, pp. 1341-1347
-
-
Cruz, J.C.1
Thomas, M.2
Wong, E.3
Ohgami, N.4
Sugii, S.5
Curphey, T.6
-
26
-
-
0028318157
-
Caged nitric oxide. Stable organic molecules from which nitric oxide can be photoreleased
-
Makings L.R., Tsien R.Y. Caged nitric oxide. Stable organic molecules from which nitric oxide can be photoreleased. J Biol Chem 1994, 269:6282-6285.
-
(1994)
J Biol Chem
, vol.269
, pp. 6282-6285
-
-
Makings, L.R.1
Tsien, R.Y.2
-
27
-
-
24044434625
-
Photoswitchable cluster glycosides as tools to probe carbohydrate-protein interactions: synthesis and lectin-binding studies of azobenzene containing multivalent sugar ligands
-
Srinivas O., Mitra N., Surolia A., Jayaraman N. Photoswitchable cluster glycosides as tools to probe carbohydrate-protein interactions: synthesis and lectin-binding studies of azobenzene containing multivalent sugar ligands. Glycobiology 2005, 15:861-873.
-
(2005)
Glycobiology
, vol.15
, pp. 861-873
-
-
Srinivas, O.1
Mitra, N.2
Surolia, A.3
Jayaraman, N.4
-
28
-
-
1842531328
-
Photolysis of caged phosphatidic acid induces flagellar excision in Chlamydomonas
-
Goedhart J., Gadella T.W. Photolysis of caged phosphatidic acid induces flagellar excision in Chlamydomonas. Biochemistry 2004, 43:4263-4271.
-
(2004)
Biochemistry
, vol.43
, pp. 4263-4271
-
-
Goedhart, J.1
Gadella, T.W.2
-
29
-
-
70149121926
-
Photoregulated release of caged anticancer drugs from gold nanoparticles
-
Agasti S.S., Chompoosor A., You C.C., Ghosh P., Kim C.K., Rotello V.M. Photoregulated release of caged anticancer drugs from gold nanoparticles. J Am Chem Soc 2009, 131:5728-5729.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 5728-5729
-
-
Agasti, S.S.1
Chompoosor, A.2
You, C.C.3
Ghosh, P.4
Kim, C.K.5
Rotello, V.M.6
-
30
-
-
77950344697
-
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate
-
Choi S.K., Thomas T., Li M.H., Kotlyar A., Desai A., Baker J.R. Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem Commun 2010, 46:2632-2634.
-
(2010)
Chem Commun
, vol.46
, pp. 2632-2634
-
-
Choi, S.K.1
Thomas, T.2
Li, M.H.3
Kotlyar, A.4
Desai, A.5
Baker, J.R.6
-
32
-
-
24344456096
-
Chemical approaches for investigating phosphorylation in signal transduction networks
-
Rothman D.M., Shults M.D., Imperiali B. Chemical approaches for investigating phosphorylation in signal transduction networks. Trends Cell Biol 2005, 15:502-510.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 502-510
-
-
Rothman, D.M.1
Shults, M.D.2
Imperiali, B.3
-
33
-
-
33746734322
-
Biologically active molecules with a "Light switch"
-
Mayer G., Heckel A. Biologically active molecules with a "Light switch" Angew Chem Intl Ed 2006, 45:4900-4921.
-
(2006)
Angew Chem Intl Ed
, vol.45
, pp. 4900-4921
-
-
Mayer, G.1
Heckel, A.2
-
34
-
-
67649243556
-
Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds
-
Lee H.-M., Larson D.R., Lawrence D.S. Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds. ACS Chem Biol 2009, 4:409-427.
-
(2009)
ACS Chem Biol
, vol.4
, pp. 409-427
-
-
Lee, H.-M.1
Larson, D.R.2
Lawrence, D.S.3
-
35
-
-
0033973662
-
Structure-activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin
-
Fischer P.M., Zhelev N.Z., Wang S., Melville J.E., Fahraeus R., Lane D.P. Structure-activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin. J Pept Res 2000, 55:163-172.
-
(2000)
J Pept Res
, vol.55
, pp. 163-172
-
-
Fischer, P.M.1
Zhelev, N.Z.2
Wang, S.3
Melville, J.E.4
Fahraeus, R.5
Lane, D.P.6
-
36
-
-
0029761653
-
De novo antimicrobial peptides with low mammalian cell toxicity
-
Javadpour M.M., Juban M.M., Lo W.C., Bishop S.M., Alberty J.B., Cowell S.M., et al. De novo antimicrobial peptides with low mammalian cell toxicity. J Med Chem 1996, 39:3107-3113.
-
(1996)
J Med Chem
, vol.39
, pp. 3107-3113
-
-
Javadpour, M.M.1
Juban, M.M.2
Lo, W.C.3
Bishop, S.M.4
Alberty, J.B.5
Cowell, S.M.6
-
37
-
-
0035907178
-
New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties
-
Etrych T., Jelinkova M., Rihova B., Ulbrich K. New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties. J Control Release 2001, 73:89-102.
-
(2001)
J Control Release
, vol.73
, pp. 89-102
-
-
Etrych, T.1
Jelinkova, M.2
Rihova, B.3
Ulbrich, K.4
-
38
-
-
0000385527
-
Enzymatic cleavage of side chains of synthetic water-soluble polymers
-
Drobnk J., Kopecek J., Labsky J., Rejmanova P., Exner J., Saudek V., et al. Enzymatic cleavage of side chains of synthetic water-soluble polymers. Makromol Chem 1976, 177:2833-2848.
-
(1976)
Makromol Chem
, vol.177
, pp. 2833-2848
-
-
Drobnk, J.1
Kopecek, J.2
Labsky, J.3
Rejmanova, P.4
Exner, J.5
Saudek, V.6
-
39
-
-
0035816157
-
Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes
-
Rihova B., Etrych T., Pechar M., Jelinkova M., Stastny M., Hovorka O., et al. Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes. J Control Release 2001, 74:225-232.
-
(2001)
J Control Release
, vol.74
, pp. 225-232
-
-
Rihova, B.1
Etrych, T.2
Pechar, M.3
Jelinkova, M.4
Stastny, M.5
Hovorka, O.6
-
40
-
-
0032580444
-
Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate
-
Omelyanenko V., Kopeckova P., Gentry C., Kopecek J. Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate. J Control Release 1998, 53:25-37.
-
(1998)
J Control Release
, vol.53
, pp. 25-37
-
-
Omelyanenko, V.1
Kopeckova, P.2
Gentry, C.3
Kopecek, J.4
-
41
-
-
49549170184
-
Poly[N-(2-hydroxypropyl)methacrylamide] I. Radical polymerization and copolymerization
-
Kopecek J.B.H. Poly[N-(2-hydroxypropyl)methacrylamide] I. Radical polymerization and copolymerization. Eur Polym J 1973, 9:7-14.
-
(1973)
Eur Polym J
, vol.9
, pp. 7-14
-
-
Kopecek, J.B.H.1
-
42
-
-
0019627519
-
Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction
-
Sarin V.K., Kent S.B., Tam J.P., Merrifield R.B. Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction. Anal Biochem 1981, 117:147-157.
-
(1981)
Anal Biochem
, vol.117
, pp. 147-157
-
-
Sarin, V.K.1
Kent, S.B.2
Tam, J.P.3
Merrifield, R.B.4
-
43
-
-
33748343425
-
A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity
-
Law B., Quinti L., Choi Y., Weissleder R., Tung C.H. A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity. Mol Cancer Ther 2006, 5:1944-1949.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1944-1949
-
-
Law, B.1
Quinti, L.2
Choi, Y.3
Weissleder, R.4
Tung, C.H.5
-
44
-
-
0035503496
-
A proapoptotic peptide for the treatment of solid tumors
-
Mai J.C., Mi Z., Kim S.H., Ng B., Robbins P.D. A proapoptotic peptide for the treatment of solid tumors. Cancer Res 2001, 61:7709-7712.
-
(2001)
Cancer Res
, vol.61
, pp. 7709-7712
-
-
Mai, J.C.1
Mi, Z.2
Kim, S.H.3
Ng, B.4
Robbins, P.D.5
-
45
-
-
34250818700
-
Two-photon uncaging with the efficient 3,5-dibromo-2,4-dihydroxycinnamic caging group
-
Gagey N., Neveu P., Jullien L. Two-photon uncaging with the efficient 3,5-dibromo-2,4-dihydroxycinnamic caging group. Angew Chem Int Ed Engl 2007, 46:2467-2469.
-
(2007)
Angew Chem Int Ed Engl
, vol.46
, pp. 2467-2469
-
-
Gagey, N.1
Neveu, P.2
Jullien, L.3
-
46
-
-
70349782203
-
Two-photon absorption and the design of two-photon dyes
-
Pawlicki M., Collins H.A., Denning R.G., Anderson H.L. Two-photon absorption and the design of two-photon dyes. Angew Chem Int Ed Engl 2009, 48:3244-3266.
-
(2009)
Angew Chem Int Ed Engl
, vol.48
, pp. 3244-3266
-
-
Pawlicki, M.1
Collins, H.A.2
Denning, R.G.3
Anderson, H.L.4
|