Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

PLoS Genetics

Volumn 10, Issue 1, 2014, Pages

  Service, Susan K ^a   Teslovich, Tanya M ^b   Fuchsberger, Christian ^b   Ramensky, Vasily ^a   Yajnik, Pranav ^b   Koboldt, Daniel C ^c   Larson, David E ^c   Zhang, Qunyuan ^c   Lin, Ling ^c   Welch, Ryan ^b   Ding, Li ^c   McLellan, Michael D ^c   O'Laughlin, Michele ^c   Fronick, Catrina ^c   Fulton, Lucinda L ^c   Magrini, Vincent ^c   Swift, Amy ^d   Elliott, Paul ^e   Jarvelin, Marjo Riitta ^e,f,g,h   Kaakinen, Marika ^e,f   McCarthy, Mark I ^i,j,k   Peltonen, Leena ^l,m   Pouta, Anneli ^f,h   Bonnycastle, Lori L ^d   Collins, Francis S ^d   Narisu, Narisu ^d   Stringham, Heather M ^b   Tuomilehto, Jaakko ^h   Ripatti, Samuli ^l,n   Fulton, Robert S ^c   Sabatti, Chiara ^o   Wilson, Richard K ^c   Boehnke, Michael ^b   Freimer, Nelson B ^a   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF OULU   (Finland)

^g OULU UNIVERSITY HOSPITAL   (Finland)

^h NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

^j UNIVERSITY OF OXFORD   (United Kingdom)

^k CHURCHILL HOSPITAL   (United Kingdom)

^l UNIVERSITY OF HELSINKI   (Finland)

^m BROAD INSTITUTE OF MIT AND HARVARD   (United States)

ⁿ WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^o STANFORD UNIVERSITY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ABCA1 GENE; ABCG8 GENE; APOA1 GENE; ARTICLE; CETP GENE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; G6PC2 GENE; GENE; GENE FREQUENCY; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC TRAIT; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INSULIN BLOOD LEVEL; LIPC GENE; LPL GENE; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

CHOLESTEROL; CHOLESTEROL, HDL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FINLAND; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LINKAGE DISEQUILIBRIUM; PHENOTYPE; POPULATION GROUPS; QUANTITATIVE TRAIT LOCI;

EID: 84896701941     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004147     Document Type: Article

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