Cross-activating invariant NKT cells and Kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Duwaerts, Caroline C ^a,c   Sun, Eric P ^a   Cheng, Chao Wen ^a,d   Van Rooijen, Nico ^b   Gregory, Stephen H ^a  

^a BROWN UNIVERSITY   (United States)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; INDUCIBLE NITRIC OXIDE SYNTHASE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; ODULIMOMAB;

ANIMAL CELL; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CELL ACTIVATION; CELL ISOLATION; CHOLESTASIS; CONTROLLED STUDY; DISEASE MODEL; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; INVARIANT NATURAL KILLER CELL; KUPFFER CELL; LIVER RESECTION; MOUSE; NATURAL KILLER CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

ANIMALS; CHOLESTASIS; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; KUPFFER CELLS; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NATURAL KILLER T-CELLS; NITRIC OXIDE SYNTHASE TYPE II; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84896700707     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079702     Document Type: Article

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