Mathematical Modeling of Heterogeneous Electrophysiological Responses in Human β-Cells

PLoS Computational Biology

Volumn 10, Issue 1, 2014, Pages

  Riz, Michela ^a   Braun, Matthias ^b   Pedersen, Morten Gram ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ELECTROPHYSIOLOGY; INSULIN;

ACTION-POTENTIALS; CA 2+; CELL INHIBITION; ELECTRICAL ACTIVITIES; ELECTROPHYSIOLOGICAL RESPONSE; FIRING FREQUENCY; GLUCOSE-STIMULATED INSULIN SECRETIONS; INSULIN SECRETION; ION CHANNEL; POTASSIUM CURRENTS;

CELLS;

4 AMINOBUTYRIC ACID A RECEPTOR; CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; GLUCAGON LIKE PEPTIDE 1; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL HETEROGENEITY; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; ENDOPLASMIC RETICULUM; GLUCOSE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; HYPERPOLARIZATION; INSULIN RELEASE; MATHEMATICAL MODEL; MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; NEUROTRANSMISSION; NONHUMAN; PANCREAS ISLET BETA CELL; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ALGORITHMS; ANIMALS; COMPUTATIONAL BIOLOGY; ELECTROPHYSIOLOGICAL PHENOMENA; GLUCOSE; GLYCOLYSIS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MODELS, THEORETICAL; OSCILLOMETRY; PANCREAS; POTASSIUM; SODIUM CHANNELS; TETRODOTOXIN;

EID: 84896698359     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003389     Document Type: Article

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