Proteomic analysis of tendon extracellular matrix reveals disease stage-specific fragmentation and differential cleavage of COMP (cartilage oligomeric matrix protein)

Journal of Biological Chemistry

Volumn 289, Issue 8, 2014, Pages 4919-4927

  Dakin, Stephanie Georgina ^a   Smith, Roger Kenneth Whealands ^a   HeinegArd, Dick ^b   Önnerfjord, Patrik ^b   Khabut, Areej ^b   Dudhia, Jayesh ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENT STAGES; EXTRACELLULAR MATRICES; IN-VITRO; INFLAMMATORY MEDIATORS; MATRIX PROTEINS; PROTEOMIC ANALYSIS; TENDON INJURIES;

BIOCHEMISTRY; BIOLOGY;

TENDONS;

CARTILAGE OLIGOMERIC MATRIX PROTEIN; INTERLEUKIN 1BETA; PROSTAGLANDIN E2;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EQUIDAE; EXPLANT; EXTRACELLULAR MATRIX; FLEXOR TENDON INJURY; IN VITRO STUDY; MUSCLE EXCITATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN SECRETION; PROTEOMICS; QUADRUPOLE MASS SPECTROMETRY; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; TISSUE CULTURE; TISSUE STRUCTURE; WESTERN BLOTTING;

EXTRACELLULAR MATRIX; INFLAMMATION; MASS SPECTROMETRY (MS); PEPTIDES; PROTEOMICS; TENDON;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CHROMATOGRAPHY, LIQUID; CULTURE MEDIA; DINOPROSTONE; EXTRACELLULAR MATRIX; HORSES; HUMANS; INTERLEUKIN-1BETA; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROTEOMICS; TENDINOPATHY; TENDONS; TISSUE SURVIVAL;

EID: 84896696613     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.511972     Document Type: Article

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