SCOPUS 정보 검색 플랫폼

Volumn 22, Issue 6, 2014, Pages 1850-1862

Design, synthesis and biological evaluation of 7-nitro-1H-indole-2- carboxylic acid derivatives as allosteric inhibitors of fructose-1,6- bisphosphatase

(5) Bie, Jianbo a Liu, Shuainan a Zhou, Jie a Xu, Bailing a Shen, Zhufang a

a INSTITUTE OF MATERIA MEDICA (China)

Author keywords

6 Bisphosphatase inhibitor; Allosteric inhibitor; Diabetes; Fructose 1; Indole

Indexed keywords

3 ACETAMIDOPHENYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; 3 ETHYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; 3 FLUOROPHENYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; 3 ISOBUTYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; 3 METHOXYPHENYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; 4 (2 METHOXYPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID DERIVATIVE; 7 NITRO 3 PHENYL 1H INDOLE 2 CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; ETHYL 3 ACETAMIDOPHENYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 3 FLUOROPHENYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 3 ISOBUTYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 3 METHOXYPHENYL 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (2 METHOXYPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (3 CHLOROPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (3 METHOXYPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (3 METHYLPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (3 NITROPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (3,4 DIMETHOXYPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (3,4,5 TRIMETHOXYPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (4 CHLOROPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (4 METHOXYPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (4 METHYLPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 (4 NITROPHENYLAMINO) 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 [3 (ACETAMIDOPHENYL)AMINO] 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 [3 (TRIFLUOROMETHYL)PHENYLAMINO] 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 4 [4 (TRIFLUOROMETHYL)PHENYLAMINO] 7 NITRO 1H INDOLE 2 CARBOXYLIC ACID; ETHYL 7 NITRO 3 PHENYL 1H INDOLE 2 CARBOXYLIC ACID; FRUCTOSE BISPHOSPHATASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; 7-NITRO-1H-INDOLE-2-CARBOXYLIC ACID; ENZYME INHIBITOR; INDOLE DERIVATIVE; RECOMBINANT PROTEIN;

ALGORITHM; ARTICLE; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; IC 50; PREDICTION; STRUCTURE ACTIVITY RELATION; ALLOSTERISM; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; SYNTHESIS;

ALLOSTERIC REGULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME INHIBITORS; FRUCTOSE-BISPHOSPHATASE; HUMANS; INDOLES; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896694935 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2014.01.047 Document Type: Article

Times cited : (30)

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