High-resolution mass spectrometry driven discovery of peptidic danger signals in insect immunity

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Berisha, Arton ^a   Mukherjee, Krishnendu ^a   Vilcinskas, Andreas ^a   Spengler, Bernhard ^a   Römpp, Andreas ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOZYME; THERMOLYSIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; GALLERIA MELLONELLA; HEMOLYMPH; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROCOCCUS LUTEUS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DATABASE;

ANIMALS; CHEMICAL FRACTIONATION; DATABASES, PROTEIN; HEMOLYMPH; INSECTS; MASS SPECTROMETRY; PEPTIDES; PROTEOMICS; REPRODUCIBILITY OF RESULTS;

EID: 84896691236     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080406     Document Type: Article

References (33)

1. Janeway CA, Medzhitov R (2002) Innate immune recognition. Annual Review of Immunology 20: 197-216.
2. Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124: 783-801. (Pubitemid 43261452)
3. Lazzaro BP, Rolff J (2011) Immunology. Danger, microbes, and homeostasis. Science 332: 43-44.
4. Wiesner J, Vilcinskas A (2010) Antimicrobial peptides The ancient arm of the human immune system. Virulence 1: 440-464.
5. Matzinger P (2002) The danger model: A renewed sense of self. Science 296: 301-305.
6. Matzinger P (2007) Friendly and dangerous signals: is the tissue in control? Nature Immunology 8: 11-13.
7. Griesch J, Wedde M, Vilcinskas A (2000) Recognition and regulation of metalloproteinase activity in the haemolymph of Galleria mellonella: a new pathway mediating induction of humoral immune responses. Insect Biochemistry and Molecular Biology 30: 461-472. (Pubitemid 30367030)
8. Mylonakis E, Casadevall A, Ausubel FM (2007) Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi. Plos Pathogens 3: 859-865.
9. Adekoya OA, Sylte I (2009) The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential. Chemical Biology & Drug Design 73: 7-16.
10. Altincicek B, Linder M, Linder D, Preissner KT, Vilcinskas A (2007) Microbial metalloproteinases mediate sensing of invading pathogens and activate innate immune responses in the lepidopteran model host Galleria mellonella. Infection and Immunity 75: 175-183. (Pubitemid 46047891)
11. Eng JK, McCormack AL, Yates JR (1994) An Approach to Correlate Tandem Mass-Spectral Data of Peptides with Amino-Acid-Sequences in a Protein Database. Journal of the American Society for Mass Spectrometry 5: 976-989.
12. Perkins DN, Pappin DJC, Creasy DM, Cottrell JS (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 20: 3551-3567. (Pubitemid 30007252)
13. Vogel H, Altincicek B, Gloeckner G, Vilcinskas A (2011) A comprehensive transcriptome and immune-gene repertoire of the lepidopteran model host Galleria mellonella. Bmc Genomics 12: 1-19.
14. Altincicek B, Berisha A, Mukherjee K, Spengler B, Roempp A, et al. (2009) Identification of collagen IV derived danger/alarm signals in insect immunity by nanoLC-FTICR MS. Biological Chemistry 390: 1303-1311.
15. Römpp A, Dekker L, Taban I, Jenster G, Boogerd W, et al. (2007) Identification of leptomeningeal metastasis-related proteins in cerebrospinal fluid of patients with breast cancer by a combination of MALDI-TOF, MALDI-FTICR and nanoLC-FTICR MS. Proteomics 7: 474-481. (Pubitemid 46293990)
16. Schober Y, Schramm T, Spengler B, Römpp A (2011) Protein identification by accurate mass matrix-assisted laser desorption/ionization imaging of tryptic peptides. Rapid Communications in Mass Spectrometry 25: 2475-2483.
17. Scigelova M, Makarov A (2006) Orbitrap mass analyzer - overview and applications in proteomics. Proteomics 6 Suppl 2: 16-21. (Pubitemid 44625764)
18. Marshall AG, Hendrickson CL (2002) Fourier transform ion cyclotron resonance detection: principles and experimental configurations. International Journal of Mass Spectrometry 215: 59-75.
19. Römpp A, Taban IM, Mihalca R, Duursma MC, Mize TH, et al. (2005) Examples of Fourier transform ion cyclotron resonance mass spectrometry developments: from ion physics to remote access biochemical mass spectrometry. European Journal of Mass Spectrometry 11: 443-456. (Pubitemid 41796532)
20. Spengler B (2004) De novo sequencing, peptide composition analysis, and composition-based sequencing: A new strategy employing accurate mass determination by Fourier transform ion cyclotron resonance mass spectrometry. Journal of the American Society for Mass Spectrometry 15: 703-714.
21. Langsdorf M, Ghassempour A, Römpp A, Spengler B (2010) Characterization of a peptide family from the skin secretion of the Middle East Tree Frog Hyla savignyi by composition-based de novo sequencing. Rapid Communications in Mass Spectrometry 24: 2885-2899.
22. Keil B (1992) Specificity of Proteolysis. Berlin-Heidelberg-New York: Springer. 336 p.
23. Nesvizhskii AI, Vitek O, Aebersold R (2007) Analysis and validation of proteomic data generated by tandem mass spectrometry. Nature Methods 4: 787-797. (Pubitemid 350055575)
24. Spengler B (2007) Accurate mass as a bioinformatic parameter in data-to-knowledge conversion: Fourier transform ion cyclotron resonance mass spectrometry for peptide de novo sequencing. European Journal of Mass Spectrometry 13: 83-87.
25. Vilcinskas A, Matha V (1997) Effect of the entomopathogenic fungus Beauveria bassiana on the humoral immune response of Galleria mellonella larvae (Lepidoptera: Pyralidae). European Journal of Entomology 94: 461-472. (Pubitemid 127556471)
26. Altincicek B, Vilcinskas A (2006) Metamorphosis and collagen-IV-fragments stimulate innate immune response in the greater wax moth, Galleria mellonella. Developmental and Comparative Immunology 30: 1108-1118. (Pubitemid 44108151)
27. Reidegeld KA, Eisenacher M, Kohl M, Chamrad D, Korting G, et al. (2008) An easy-to-use Decoy Database Builder software tool, implementing different decoy strategies for false discovery rate calculation in automated MS/MS protein identifications. Proteomics 8: 1129-1137. (Pubitemid 351462918)
28. Vilcinskas A (2011) ANTI-infective Therapeutics from the Lepidopteran Model Host Galleria mellonella. Current Pharmaceutical Design 17: 1240-1245.
29. Vilcinskas A (2010) Coevolution between pathogen-derived proteinases and proteinase inhibitors of host insects. Virulence 1: 206-214.
30. Vilcinskas A, Wedde M (2002) Insect inhibitors of metalloproteinases. IUBMB Life 54: 339-343. (Pubitemid 36298253)
31. Wedde M, Weise C, Nuck R, Altincicek B, Vilcinskas A (2007) The insect metalloproteinase inhibitor gene of the lepidopteran Galleria mellonella encodes two distinct inhibitors. Biological Chemistry 388: 119-127. (Pubitemid 46090180)
32. Clermont A, Wedde M, Seitz V, Podsiadlowski L, Lenze D, et al. (2004) Cloning and expression of an inhibitor of microbial metalloproteinases from insects contributing to innate immunity. Biochemical Journal 382: 315-322. (Pubitemid 39141595)
33. Vilcinskas A (2013) Evolutionary plasticity of insect immunity. Journal of Insect Physiology 59: 123-129.