Noninvasive technique for monitoring drug transport through the murine cochlea using micro-computed tomography

Annals of Biomedical Engineering

Volumn 41, Issue 10, 2013, Pages 2130-2142

  Haghpanahi, Masoumeh ^a   Gladstone, Miriam B ^c   Zhu, Xiaoxia ^b   Frisina, Robert D ^b,c,d   Borkholder, David A ^a,c,d  

^a Rochester Institute of Technology   (United States)

^b University of South Florida   (United States)

^c University of Rochester   (United States)

^d UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Automatic segmentation; Cochlea; Computed tomography; Drug delivery; Image registration; Inner ear; Mouse; Pharmacokinetics

Indexed keywords

AUTOMATIC SEGMENTATIONS; COCHLEA; DIFFUSION PARAMETERS; INNER EAR; MICROCOMPUTED TOMOGRAPHY; MOUSE; NON-INVASIVE IMAGING; NONINVASIVE TECHNIQUE;

AUDITION; DRUG DELIVERY; IMAGE REGISTRATION; IMAGE SEGMENTATION; IMAGING TECHNIQUES; MAMMALS; MATHEMATICAL MODELS; PHARMACOKINETICS;

COMPUTERIZED TOMOGRAPHY;

IOVERSOL; CONTRAST MEDIUM; IODOBENZOIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; COCHLEA; CONTINUOUS INFUSION; DRUG CLEARANCE; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG MONITORING; DRUG TRANSPORT; MEASUREMENT ACCURACY; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NON INVASIVE PROCEDURE; NONHUMAN; ACTIVE TRANSPORT; ANIMAL; BIOLOGICAL MODEL; FEMALE; MALE; METABOLISM; PROCEDURES; RADIOGRAPHY;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; COCHLEA; CONTRAST MEDIA; FEMALE; MALE; MICE; MODELS, BIOLOGICAL; TRIIODOBENZOIC ACIDS; X-RAY MICROTOMOGRAPHY;

EID: 84896690757     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-013-0816-4     Document Type: Article

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