Effects of fluid resuscitation with 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis

Critical Care Medicine

Volumn 42, Issue 4, 2014, Pages

  Zhou, Feihu ^a,b   Peng, Zhi Yong ^a   Bishop, Jeffery V ^a   Cove, Matthew E ^a,c   Singbartl, Kai ^a,d   Kellum, John A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c Center for Critical Care Nephrology Department of Critical Care Medicine University of Pittsburgh School of Medicine ^*  (Singapore)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

acute kidney injury; hyperchloremia; saline; sepsis

Indexed keywords

ACETIC ACID PLUS GLUCONATE SODIUM PLUS MAGNESIUM CHLORIDE PLUS POTASSIUM CHLORIDE PLUS SODIUM CHLORIDE; CHLORIDE; CREATININE; CYSTATIN C; INTERLEUKIN 6; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; POTASSIUM; SODIUM CHLORIDE;

ACUTE KIDNEY FAILURE; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GAS; CHLORIDE BLOOD LEVEL; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; CRYSTALLOID; ELECTROLYTE BLOOD LEVEL; FLUID RESUSCITATION; KIDNEY FUNCTION; MALE; NONHUMAN; PH; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; RAT; SEPSIS; SURVIVAL; SURVIVAL TIME; URINALYSIS;

ACIDOSIS; ACUTE KIDNEY INJURY; ANIMALS; BIOLOGICAL MARKERS; BLOOD CHEMICAL ANALYSIS; DISEASE MODELS, ANIMAL; ELECTROLYTES; FLUID THERAPY; HEMATOLOGIC TESTS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RESUSCITATION; SEPSIS; SEVERITY OF ILLNESS INDEX; SODIUM CHLORIDE; URINALYSIS;

EID: 84896622151     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000145     Document Type: Article

References (36)

1. Awad S, Allison SP, Lobo DN: The history of 0.9% saline. Clin Nutr 2008; 27:179-188
2. Scheingraber S, Rehm M, Sehmisch C, et al: Rapid saline infusion produces hyperchloremic acidosis in patients undergoing gynecologic surgery. Anesthesiology 1999; 90:1265-1270
3. Wilcox CS: Regulation of renal blood fow by plasma chloride. J Clin Invest 1983; 71:726-735
4. Hansen PB, Jensen BL, Skott O: Chloride regulates afferent arteriolar contraction in response to depolarization. Hypertension 1998; 32:1066-1070
5. Imig JD, Passmore JC, Anderson GL, et al: Chloride alters renal blood fow autoregulation in deoxycorticosterone-treated rats. J Lab Clin Med 1993; 121:608-613
6. Chowdhury AH, Cox EF, Francis ST, et al: A randomized, controlled, double-blind crossover study on the effects of 2-L infusions of 0.9% saline and plasma-lyte® 148 on renal blood fow velocity and renal cortical tissue perfusion in healthy volunteers. Ann Surg 2012; 256:18-24
7. Kellum JA, Song M, Venkataraman R: Effects of hyperchloremic acidosis on arterial pressure and circulating infammatory molecules in experimental sepsis. Chest 2004; 125:243-248
8. Kellum JA, Song M, Almasri E: Hyperchloremic acidosis increases circulating infammatory molecules in experimental sepsis. Chest 2006; 130:962-967
9. Shaw AD, Bagshaw SM, Goldstein SL, et al: Major complications, mortality, and resource utilization after open abdominal surgery: 0.9% saline compared to Plasma-Lyte. Ann Surg 2012; 255:821-829
10. Yunos N M, Bellomo R, Hegarty C, et al: Association between a chloride-liberal vs chloride-restrictive intravenous fuid administration strategy and kidney injury in critically ill adults. JAMA 2012; 308:1566-1572
11. Stephens R, Mythen M: Optimizing intraoperative fuid therapy. Curr Opin Anaesthesiol 2003; 16:385-392
12. Lobo DN: Intravenous 0.9% saline and general surgical patients: A problem, not a solution. Ann Surg 2012; 255:830-832
13. Peng ZY, Wang HZ, Srisawat N, et al: Bactericidal antibiotics temporarily increase infammation and worsen acute kidney injury in experimental sepsis. Crit Care Med 2012; 40:538-543
14. Peng ZY, Wang HZ, Carter MJ, et al: Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purifcation in experimental sepsis. Kidney Int 2012; 81:363-369
15. Maitland K, Kiguli S, Opoka RO, et al; FEAST Trial Group: Mortality after fuid bolus in African children with severe infection. N Engl J Med 2011; 364:2483-2495
16. Guidet B, Soni N, Della Rocca G, et al: A balanced view of balanced solutions. Crit Care 2010; 14:325
17. Salomonsson M, Gonzalez E, Kornfeld M, et al: The cytosolic chloride concentration in macula densa and cortical thick ascending limb cells. Acta Physiol Scand 1993; 147:305-313
18. Hashimoto S, Kawata T, Schnermann J, et al: Chloride channel blockade attenuates the effect of angiotensin II on tubuloglomerular feedback in WKY but not spontaneously hypertensive rats. Kidney Blood Press Res 2004; 27:35-42
19. Bullivant EM, Wilcox CS, Welch WJ: Intrarenal vasoconstriction during hyperchloremia: Role of thromboxane. Am J Physiol 1989; 256:F152-F157
20. Quilley CP, Lin YS, McGiff JC: Chloride anion concentration as a determinant of renal vascular responsiveness to vasoconstrictor agents. Br J Pharmacol 1993; 108:106-110
21. Jensen JC, Buresh C, Norton JA: Lactic acidosis increases tumor necrosis factor secretion and transcription in vitro. J Surg Res 1990; 49:350-353
22. Kellum JA, Song M, Li J: Lactic and hydrochloric acids induce different patterns of infammatory response in LPS-stimulated RAW 264.7 cells. Am J Physiol Regul Integr Comp Physiol 2004; 286:R686-R692
23. Kellum JA: Fluid resuscitation and hyperchloremic acidosis in experimental sepsis: Improved short-term survival and acid-base balance with Hextend compared with saline. Crit Care Med 2002; 30:300-305
24. Almac E, Aksu U, Bezemer R, et al: The acute effects of acetate-balanced colloid and crystalloid resuscitation on renal oxygenation in a rat model of hemorrhagic shock. Resuscitation 2012; 83:1166-1172
25. Todd SR, Malinoski D, Muller PJ, et al: Lactated Ringer's is superior to normal saline in the resuscitation of uncontrolled hemorrhagic shock. J Trauma 2007; 62:636-639
26. Pedoto A, Nandi J, Oler A, et al: Role of nitric oxide in acidosis-induced intestinal injury in anesthetized rats. J Lab Clin Med 2001; 138:270-276
27. Pedoto A, Caruso JE, Nandi J, et al: Acidosis stimulates nitric oxide production and lung damage in rats. Am J Respir Crit Care Med 1999; 159:397-402
28. Murugan R, Karajala-Subramanyam V, Lee M, et al; Genetic and Infammatory Markers of Sepsis (GenIMS) Investigators: Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int 2010; 77:527-535
29. Leung JC, Lam MF, Tang SC, et al: Roles of neutrophil gelatinase-associated lipocalin in continuous ambulatory peritoneal dialysis-related peritonitis. J Clin Immunol 2009; 29:365-378
30. Xu SY, Pauksen K, Venge P: Serum measurements of human neutrophil lipocalin (HNL) discriminate between acute bacterial and viral infections. Scand J Clin Lab Invest 1995; 55:125-131
31. Mårtensson J, Bell M, Oldner A, et al: Neutrophil gelatinase-associ-ated lipocalin in adult septic patients with and without acute kidney injury. Intensive Care Med 2010; 36:1333-1340
32. Augustinsson O, Forslid A: Aldosterone secretion during acute respiratory acidosis and NH4Cl-induced metabolic acidosis in the goat. Acta Physiol Scand 1989; 136:339-345
33. Wood CE, Chen HG: Acidemia stimulates ACTH, vasopressin, and heart rate responses in fetal sheep. Am J Physiol 1989; 257:R344-R349
34. Ayala A, Perrin MM, Chaudry IH: Defective macrophage antigen presentation following haemorrhage is associated with the loss of MHC class II (Ia) antigens. Immunology 1990; 70:33-39
35. Reid F, Lobo DN, Williams RN, et al: (Ab)normal saline and physiological Hartmann's solution: A randomized double-blind crossover study. Clin Sci (Lond) 2003; 104:17-24
36. Lobo DN, Stanga Z, Simpson JA, et al: Dilution and redistribution effects of rapid 2-litre infusions of 0.9% (w/v) saline and 5% (w/v) dextrose on haematological parameters and serum biochemistry in normal subjects: A double-blind crossover study. Clin Sci (Lond) 2001; 101:173-179