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Volumn 10, Issue 4, 2014, Pages 455-471

Stem Cell Research Funding Policies and Dynamic Innovation: A Survey of Open Access and Commercialization Requirements

Author keywords

Commercialization; Data sharing; Human embryonic stem cells (hESC); Induced pluripotent stem cells (iPSC); Open access; Stem cell research (SCR)

Indexed keywords


EID: 84896590096     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-014-9504-5     Document Type: Article
Times cited : (7)

References (127)
  • 1
    • 84927531050 scopus 로고    scopus 로고
    • Digital Curation Center, Edinburgh: Available at http://www.dcc.ac.uk/sites/default/files/documents/CrossCouncilPolicyOverview.pdf. Accessed 28 Nov 2013
    • Jones, S. (2012). Curation policies and support services of the main UK research funders. Edinburgh: Digital Curation Center. Available at http://www.dcc.ac.uk/sites/default/files/documents/CrossCouncilPolicyOverview.pdf. Accessed 28 Nov 2013.
    • (2012) Curation policies and support services of the main UK research funders
    • Jones, S.1
  • 2
    • 84857434745 scopus 로고    scopus 로고
    • Open science versus commercialization: a modern research conflict?
    • PID: 22369790
    • Caulfield, T., Harmon, H. E. S., & Joly, Y. (2012). Open science versus commercialization: a modern research conflict? Genome Medicine, 4(2), 17–28.
    • (2012) Genome Medicine , vol.4 , Issue.2 , pp. 17-28
    • Caulfield, T.1    Harmon, H.E.S.2    Joly, Y.3
  • 3
    • 77957679836 scopus 로고    scopus 로고
    • Commercialization and collaboration: competing policies in publicly funded stem cell research?
    • COI: 1:CAS:528:DC%2BC3cXps12ktr0%3D, PID: 20621046
    • Bubela, T. (2010). Commercialization and collaboration: competing policies in publicly funded stem cell research? Cell Stem Cell, 7, 25–30.
    • (2010) Cell Stem Cell , vol.7 , pp. 25-30
    • Bubela, T.1
  • 4
    • 85019173596 scopus 로고    scopus 로고
    • Talking science commercialization creep (December 2012)
    • Caulfield, T. (2012). Talking science commercialization creep (December 2012). Available at: http://www.irpp.org/en/po/talking-science/talking-science-commercialization-creep/. Accessed 30 Oct 2013.
    • (2012) Available at:
    • Caulfield, T.1
  • 5
    • 85019212713 scopus 로고    scopus 로고
    • Report & recommendations
    • United Kingdom Stem Cell Initiative. (2005). Report & recommendations. Available at http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_4123849. Accessed 14 Sep 2012.
    • (2005) Available at
    • Initiative, U.K.S.C.1
  • 6
    • 85019236430 scopus 로고    scopus 로고
    • Canadian asset map for stem cell and regenerative medicine
    • Industry Canada. (2012). Canadian asset map for stem cell and regenerative medicine. Available at http://www.ic.gc.ca/eic/site/lsg-pdsv.nsf/eng/h_hn01743.html. Accessed 10 Sep 2012.
    • (2012) Available at
    • Canada, I.1
  • 7
    • 85019203072 scopus 로고    scopus 로고
    • Medicina Regenerativa y Terapia Celular Informe de Vigilancia Tecnológica
    • Madrid, Available at:
    • Romero, G. R., et al. (2008). Medicina Regenerativa y Terapia Celular Informe de Vigilancia Tecnológica. Genoma España, Madrid. Available at http://www.gen-es.org/assets_db/publications/documents/pub_78_d.pdf. Accessed 28 Nov 2013.
    • (2008) Genoma España
    • Romero, G.R.1
  • 8
    • 70349869179 scopus 로고    scopus 로고
    • Governing stem cell banks and registries: emerging issues
    • PID: 19586808
    • Isasi, R. M., & Knoppers, B. M. (2009). Governing stem cell banks and registries: emerging issues. Stem Cell Research, 3(2–3), 96–105.
    • (2009) Stem Cell Research , vol.3 , Issue.2-3 , pp. 96-105
    • Isasi, R.M.1    Knoppers, B.M.2
  • 9
    • 81555207182 scopus 로고    scopus 로고
    • From banking to international governance: fostering innovation in stem cell research
    • PID: 21904557
    • Isasi, R. M., & Knoppers, B. M. (2011). From banking to international governance: fostering innovation in stem cell research. Stem Cells International, 2011, 498132.
    • (2011) Stem Cells International , vol.2011 , pp. 498132
    • Isasi, R.M.1    Knoppers, B.M.2
  • 10
    • 77952095612 scopus 로고    scopus 로고
    • International stem cell registries
    • Stacey, G., et al. (2010). International stem cell registries. In Vitro Cellular and Developmental Biology, 46(3–4), 242–246.
    • (2010) In Vitro Cellular and Developmental Biology , vol.46 , Issue.3-4 , pp. 242-246
    • Stacey, G.1
  • 11
    • 85019175465 scopus 로고    scopus 로고
    • We performed searches with the keywords “stem cell” and “regenerative medicine”. Using the US governmental grant database (grants.gov), we eliminated returns with standard clauses on hESC research requirements. In Canada, we searched the Federal Government Support listing () and ResearchNet (). We also queried the EU Cordis portal (cordis.europa.eu).
    • We performed searches with the keywords “stem cell” and “regenerative medicine”. Using the US governmental grant database (grants.gov), we eliminated returns with standard clauses on hESC research requirements. In Canada, we searched the Federal Government Support listing (http://www.ic.gc.ca/eic/site/lsg-pdsv.nsf/eng/h_hn01725.html) and ResearchNet (http://www.researchnet-recherchenet.ca). We also queried the EU Cordis portal (cordis.europa.eu).
  • 12
    • 85019179476 scopus 로고    scopus 로고
    • The advisors are identified in the Acknowledgement section of this paper.
    • The advisors are identified in the Acknowledgement section of this paper.
  • 13
    • 85019245302 scopus 로고    scopus 로고
    • Wellcome Trust. Position Statement in Support of Open and Unrestricted Access to Published Research. Available at. Accessed 28 Nov 2013.
    • Wellcome Trust. Position Statement in Support of Open and Unrestricted Access to Published Research. Available at http://www.wellcome.ac.uk/About-us/Policy/Spotlight-issues/Open-access/Policy/index.htm. Accessed 28 Nov 2013.
  • 14
    • 85019243217 scopus 로고    scopus 로고
    • Policy on open access
    • Research Councils United Kingdom. (2013). Policy on open access. Available at http://www.rcuk.ac.uk/documents/documents/RCUKOpenAccessPolicy.pdf. Accessed 28 Nov 2013.
    • (2013) Available at
  • 15
    • 78650005097 scopus 로고    scopus 로고
    • Tracking and assessing the rise of state-funded stem cell research
    • COI: 1:CAS:528:DC%2BC3cXhsFals7bE, PID: 21139604
    • Karmali, R. N., Jones, N. M., & Levine, A. D. (2010). Tracking and assessing the rise of state-funded stem cell research. Nature Biotechnology, 28, 1246–1248.
    • (2010) Nature Biotechnology , vol.28 , pp. 1246-1248
    • Karmali, R.N.1    Jones, N.M.2    Levine, A.D.3
  • 16
    • 84864184649 scopus 로고    scopus 로고
    • Local and global returns from research in stem cells: the case of the California Institute for Regenerative Medicine
    • COI: 1:CAS:528:DC%2BC38XhtVKnsL7N, PID: 22817632
    • Alberro, J. (2012). Local and global returns from research in stem cells: the case of the California Institute for Regenerative Medicine. Regenerative Medicine, 7(4), 605–613.
    • (2012) Regenerative Medicine , vol.7 , Issue.4 , pp. 605-613
    • Alberro, J.1
  • 17
    • 84873714413 scopus 로고    scopus 로고
    • The New York stem cell foundation: accelerating cures through stem cell research
    • PID: 23197805
    • Solomon, S. L. (2012). The New York stem cell foundation: accelerating cures through stem cell research. Stem Cells Translational Medicine, 1(4), 263–265.
    • (2012) Stem Cells Translational Medicine , vol.1 , Issue.4 , pp. 263-265
    • Solomon, S.L.1
  • 18
    • 85019240039 scopus 로고    scopus 로고
    • Moving beyond commercialization: Strategies to maximize the economic and social impact of genomics research. Policy Brief No
    • Genome Canada, Ottawa:
    • Joly, Y., Dove, E. S. (2012). Moving beyond commercialization: Strategies to maximize the economic and social impact of genomics research. Policy Brief No. 5., Genome Canada, Ottawa. Available at http://www.genomecanada.ca/medias/pdf/en/GPS-Policy-brief-April2012.pdf. Accessed 28 Nov 2013.
    • (2012) 5.
    • Joly, Y.1    Dove, E.S.2
  • 19
    • 77952152932 scopus 로고    scopus 로고
    • Open biotechnology: licenses needed
    • COI: 1:CAS:528:DC%2BC3cXlslyru7w%3D, PID: 20458301
    • Joly, Y. (2010). Open biotechnology: licenses needed. Nature Biotechnology, 28, 417–419.
    • (2010) Nature Biotechnology , vol.28 , pp. 417-419
    • Joly, Y.1
  • 20
    • 33749603964 scopus 로고    scopus 로고
    • Beyond the permissibility of embryonic and stem cell research: substantive requirements and procedural safeguards
    • PID: 16877375
    • Isasi, R. M., & Knoppers, B. M. (2006). Beyond the permissibility of embryonic and stem cell research: substantive requirements and procedural safeguards. Human Reproduction, 21(10), 2474–2481.
    • (2006) Human Reproduction , vol.21 , Issue.10 , pp. 2474-2481
    • Isasi, R.M.1    Knoppers, B.M.2
  • 21
    • 84870682967 scopus 로고    scopus 로고
    • Alliance, collaborations and consortia: the international stem cell forum and its role in shaping global governance and policy
    • COI: 1:CAS:528:DC%2BC38XhslKrsr3O, PID: 23210817
    • Isasi, R. M. (2012). Alliance, collaborations and consortia: the international stem cell forum and its role in shaping global governance and policy. Regenerative Medicine, 7(6 Supp), 84–88.
    • (2012) Regenerative Medicine , vol.7 , Issue.6 Supp , pp. 84-88
    • Isasi, R.M.1
  • 22
    • 85019260304 scopus 로고    scopus 로고
    • Mission statement
    • International Society for Stem Cell Research. (2013). Mission statement. Available at http://www.isscr.org/home/about-us/mission-statement. Accessed 28 Nov 2013.
    • (2013) Available at
  • 24
    • 85019267521 scopus 로고    scopus 로고
    • Sample form
    • International Society for Stem Cell Research. (2013). Sample form, uniform hESC-related materials transfer agreement. Available at http://www.isscr.org/home/publications/guide-clintrans/sample-material-transfer-agreement. Accessed 28 Nov 2013.
    • (2013) uniform hESC-related materials transfer agreement
  • 26
    • 85019264185 scopus 로고    scopus 로고
    • About the Hinxton group
    • Hinxton Group. (2013). About the Hinxton group. Available at http://hinxtongroup.wordpress.com/about/. Accessed 28 Nov 2013.
    • (2013) Available at
  • 27
    • 85019242481 scopus 로고    scopus 로고
    • Statement on policies and practices governing data and materials sharing and intellectual property in stem cell science
    • Hinxton Group. (2010). Statement on policies and practices governing data and materials sharing and intellectual property in stem cell science. Available at http://www.hinxtongroup.org/Consensus_HG10_FINAL.pdf. Accessed 28 Nov 2013.
    • (2010) Available at
  • 28
    • 85019187340 scopus 로고    scopus 로고
    • Statement on data and materials sharing and intellectual property in pluripotent stem cell science in Japan and China
    • Hinxton Group. (2012). Statement on data and materials sharing and intellectual property in pluripotent stem cell science in Japan and China. Available at http://www.hinxtongroup.org/consensus_hg12_final.pdf. Accessed 28 Nov 2013.
    • (2012) Available at
  • 29
    • 85019247155 scopus 로고    scopus 로고
    • OECD principles and guidelines for access to research data from public funding
    • The Organisation for Economic Co-operation and Development (OECD). (2007). OECD principles and guidelines for access to research data from public funding. Available at http://www.oecd.org/sti/sci-tech/38500813.pdf. Accessed 28 Nov 2013.
    • (2007) Available at
  • 30
    • 85019252547 scopus 로고    scopus 로고
    • Oliver Brüstle v Greenpeace e.V. (2010). OJC 100/19 of 17 April 2010 (21 January 2010) (Case C 34/10) at paras 34–37.
    • Oliver Brüstle v Greenpeace e.V. (2010). OJC 100/19 of 17 April 2010 (21 January 2010) (Case C 34/10) at paras 34–37.
  • 31
    • 82755164296 scopus 로고    scopus 로고
    • The European court of justice ruling in Brüstle v. Greenpeace: the impacts on patenting of human induced pluripotent stem cells in Europe
    • COI: 1:CAS:528:DC%2BC3MXhsFOns7jM, PID: 22136925
    • Triller Vrtovec, K., & Scott, C. T. (2011). The European court of justice ruling in Brüstle v. Greenpeace: the impacts on patenting of human induced pluripotent stem cells in Europe. Cell Stem Cell, 9(6), 502–503.
    • (2011) Cell Stem Cell , vol.9 , Issue.6 , pp. 502-503
    • Triller Vrtovec, K.1    Scott, C.T.2
  • 32
    • 84890552925 scopus 로고    scopus 로고
    • After Brustle EU accession to the ECHR and the future of european patent law
    • Plomer, A. (2012). After Brustle EU accession to the ECHR and the future of european patent law. Queen Mary Journal of Intellectual Property, 2(2), 110–135.
    • (2012) Queen Mary Journal of Intellectual Property , vol.2 , Issue.2 , pp. 110-135
    • Plomer, A.1
  • 33
    • 85019205794 scopus 로고    scopus 로고
    • FP7. Open Access Pilot in FP7. Available at. Accessed 28 Nov 2013.
    • FP7. Open Access Pilot in FP7. Available at ftp://ftp.cordis.europa.eu/pub/fp7/docs/open-access-pilot_en.pdf. Accessed 28 Nov 2013.
  • 34
    • 85019201727 scopus 로고    scopus 로고
    • This result was found by entering “stem cell” in the CORDIS search engine.
    • This result was found by entering “stem cell” in the CORDIS search engine.
  • 35
    • 85019245897 scopus 로고    scopus 로고
    • FP7. (2012). Guide to intellectual property rules for FP7 projects. Available at. Accessed 28 Nov 2013.
    • FP7. (2012). Guide to intellectual property rules for FP7 projects. Available at http://ec.europa.eu/research/participants/portal/ShowDoc/Extensions+Repository/General+Documentation/Guidance+documents+for+FP7/Intellectual+property+rules/ipr_en.pdf. Accessed 28 Nov 2013.
  • 37
    • 85019219998 scopus 로고    scopus 로고
    • Regulation (EC) No 1906/2006 of the European Parliament and of the Council of 18 December 2006, laying down the rules for the participation of undertakings
    • European Commission. (2006). Regulation (EC) No 1906/2006 of the European Parliament and of the Council of 18 December 2006, laying down the rules for the participation of undertakings, research centres and universities in actions under the Seventh Framework Programme and for the dissemination of research results (2007–2013). Available at http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2006:391:0001:0018:EN:PDF. Accessed 28 Nov 2013.
    • (2006) research centres and universities in actions under the Seventh Framework Programme and for the dissemination of research results (2007–2013
  • 39
    • 85019189221 scopus 로고    scopus 로고
    • We did not investigate how frequently the EU Commission actually exercises this power.
    • We did not investigate how frequently the EU Commission actually exercises this power.
  • 40
    • 84906224856 scopus 로고    scopus 로고
    • Towards commonality? Policy approaches to human embryonic stem cell research in Europe
    • Torremans P, Plomer A, (eds), Oxford University Press, New York:
    • Isasi, R., & Knoppers, B. M. (2009). Towards commonality? Policy approaches to human embryonic stem cell research in Europe. In P. Torremans & A. Plomer (Eds.), Embryonic stem cell patents: European patent law and ethics (pp. 29–56). New York: Oxford University Press.
    • (2009) Embryonic stem cell patents: European patent law and ethics , pp. 29-56
    • Isasi, R.1    Knoppers, B.M.2
  • 41
    • 85019217383 scopus 로고    scopus 로고
    • United Kingdom Stem Cell Bank (2010). Code of practice for the use of human stem cell lines, v.5. Available at. Accessed 28 Nov 2013.
    • United Kingdom Stem Cell Bank (2010). Code of practice for the use of human stem cell lines, v.5. Available at http://www.ukstemcellbank.org.uk/pdf/Code_of_Practice_for_the_Use_of_Human_Stem_Cell_Lines_(2010).pdf. Accessed 28 Nov 2013.
  • 42
    • 85019175425 scopus 로고    scopus 로고
    • Research use licence
    • United Kingdom Stem Cell Bank. (2010). Research use licence. Available at http://www.ukstemcellbank.org.uk/policies__guidelines/research_use_licence.aspx. Accessed 28 Nov 2013.
    • (2010) Available at
    • Bank, U.K.S.C.1
  • 43
    • 85019241694 scopus 로고    scopus 로고
    • United Kingdom Stem Cell Bank. Materials access agreement for human embryonic EUCTD stem cell lines v.1.00, KSCB, UKSCB, Hertfordshire.
    • United Kingdom Stem Cell Bank. Materials access agreement for human embryonic EUCTD stem cell lines v.1.00, KSCB, UKSCB, Hertfordshire.
  • 44
    • 85019188899 scopus 로고    scopus 로고
    • Strategic plan 2010–2015
    • The Biotechnology and Biological Sciences Research Council. (2010). Strategic plan 2010–2015. Available at http://www.bbsrc.ac.uk/publications/planning/strategy/strategic-plan-index.aspx. Accessed 28 Nov 2013.
    • (2010) Available at
  • 45
    • 85019246404 scopus 로고    scopus 로고
    • The replacement
    • The Biotechnology and Biological Sciences Research Council. (2012). The replacement, refinement and reduction (3Rs) in research using animals. Available at http://www.bbsrc.ac.uk/funding/priorities/oa-3rs.aspx. Accessed 28 Nov 2013.
    • (2012) refinement and reduction (3Rs) in research using animals
  • 46
    • 85019215598 scopus 로고    scopus 로고
    • Knowledge exchange and commercialization policy
    • The Biotechnology and Biological Sciences Research Council. (2012). Knowledge exchange and commercialization policy. Available at http://www.bbsrc.ac.uk/organisation/policies/position/policy/knowledge-exchange-commercialisation.aspx. Accessed 28 Nov 2013.
    • (2012) Available at
  • 47
    • 85019249703 scopus 로고    scopus 로고
    • Grants guide
    • The Biotechnology and Biological Sciences Research Council. (2012). Grants guide. Available at http://www.bbsrc.ac.uk/web/FILES/Guidelines/grants-guide.pdf. Accessed 28 Nov 2013.
    • (2012) Available at
  • 48
    • 85019251297 scopus 로고    scopus 로고
    • The Biotechnology and Biological Sciences Research Council. (2012). Policy on maximizing the impact of research http. Accessed 28 Nov 2013.
    • The Biotechnology and Biological Sciences Research Council. (2012). Policy on maximizing the impact of research http http://www.bbsrc.ac.uk/web/FILES/Policies/bbsrc-impact-policy.pdf. Accessed 28 Nov 2013.
  • 49
    • 85019228961 scopus 로고    scopus 로고
    • Data sharing policy
    • The Biotechnology and Biological Sciences Research Council. (2010). Data sharing policy. Available at http://www.bbsrc.ac.uk/web/FILES/Policies/data-sharing-policy.pdf. Accessed 28 Nov 2013.
    • (2010) Available at
  • 50
    • 85019246609 scopus 로고    scopus 로고
    • Intellectual property policy
    • The Biotechnology and Biological Sciences Research Council. (2013). Intellectual property policy. Available at http://www.bbsrc.ac.uk/web/FILES/Policies/intellectual_property_policy.pdf. Accessed 28 Nov 2013.
    • (2013) Available at
  • 51
    • 85019212686 scopus 로고    scopus 로고
    • Charter of the medical research council
    • Medical Research Council. (2003). Charter of the medical research council. Available at http://www.mrc.ac.uk/Utilities/Documentrecord/index.htm?d=MRC002423. Accessed 28 Nov 2013.
    • (2003) Available at
  • 52
    • 85019220469 scopus 로고    scopus 로고
    • MRC policy on research and data sharing
    • Medical Research Council. (2012). MRC policy on research and data sharing. Available at http://www.mrc.ac.uk/Ourresearch/Ethicsresearchguidance/datasharing/Policy/index.htm. Accessed 28 Nov 2013.
    • (2012) Available at
  • 53
    • 85019203007 scopus 로고    scopus 로고
    • UK-China Stem cell partnership development initiative
    • Medical Research Council. (2012). UK-China Stem cell partnership development initiative. Available at http://www.mrc.ac.uk/Fundingopportunities/Calls/UK-China_Stemcell/MRC008437. Accessed 28 Nov 2013.
    • (2012) Available at
  • 54
    • 85019184226 scopus 로고    scopus 로고
    • Regenerative medicine research committee, Available at:
    • Medical Research Council. (2012). Biomedical catalyst: Regenerative medicine research committee. Available at http://www.mrc.ac.uk/Newspublications/News/MRC004680. Accessed 28 Nov 2013.
    • (2012) Biomedical catalyst
  • 55
    • 85019267507 scopus 로고    scopus 로고
    • MRC Industry Collaboration Agreement (MICA)
    • Medical Research Council. (2012). MRC Industry Collaboration Agreement (MICA). Available at http://www.mrc.ac.uk/Fundingopportunities/Grants/MICA/Specification/index.htm. Accessed 28 Nov 2013.
    • (2012) Available at
  • 56
    • 85019229029 scopus 로고    scopus 로고
    • Driving innovation
    • The Technology Strategy Board. (2012). Driving innovation. Available at http://www.innovateuk.org. Accessed 13 Feb 2014.
    • (2012) Available at
  • 57
    • 85019187006 scopus 로고    scopus 로고
    • Annual report and accounts 2010–2011
    • The Technology Strategy Board. (2012). Annual report and accounts 2010–2011. Available at http://www.official-documents.gov.uk/document/hc1213/hc00/0012/0012.asp. Accessed 28 Nov 2013.
    • (2012) Available at
  • 58
    • 85019219168 scopus 로고    scopus 로고
    • CRACK IT challenge, Available at:
    • The Technology Strategy Board. (2011). Invitation to tender, CRACK IT challenge. Available at http://www.innovateuk.org/_assets/0511/invitation_to_tender_final_-_compiled.pdf. Accessed 28 Nov 2013.
    • (2011) Invitation to tender
  • 59
    • 85019187189 scopus 로고    scopus 로고
    • Download the Brief, Available at:
    • The Technology Strategy Board. (2011). Regenerative medicine programme: Developing therapeutics 2. Download the Brief. Available at http://webarchive.nationalarchives.gov.uk/20130221185318/http://www.innovateuk.org/content/competition/regenerative-medicine-programme-developing-therape1.ashx. Accessed 28 Nov 2013.
    • (2011) Regenerative medicine programme: Developing therapeutics 2
  • 60
    • 85019249889 scopus 로고    scopus 로고
    • The Technology Strategy Board. (2013). Available at:. Accessed 13 Feb 2014.
    • The Technology Strategy Board. (2013). Available at: https://www.innovateuk.org/-/funding-rules?redirect=https%3A%2F%2Fwww.innovateuk.org%2Fguidance-for-applicants%3Fp_p_id%3D101_INSTANCE_b61wJfKPbeu8%26p_p_lifecycle%3D0%26p_p_state%3Dnormal%26p_p_mode%3Dview%26p_p_col_id%3Dcolumn-1%26p_p_col_count%3D1#collaboration. Accessed 13 Feb 2014.
  • 61
    • 85019190091 scopus 로고    scopus 로고
    • Project costs
    • The Technology Strategy Board. (2013). “Project costs” guidance. Available at https://www.innovateuk.org/web/corporate1/guidance-for-applicants/-/asset_publisher/b61wJfKPbeu8/content/project-costs. Accessed 28 Nov 2013.
    • (2013) guidance
  • 62
    • 85019208513 scopus 로고    scopus 로고
    • Pfizer to develop pioneering stem cell sight therapies
    • UCL News. (24 April 2009). Pfizer to develop pioneering stem cell sight therapies. Available at: http://www.ucl.ac.uk/news/news-articles/0904/09042301. Accessed 28 Nov 2013.
    • (2009) Available at:
    • UCL, N.1
  • 63
    • 84856429199 scopus 로고    scopus 로고
    • Innovation and research strategy for growth, Available at:
    • United Kingdom Department for Business, Innovation and Skills. (2011). Innovation and research strategy for growth. Available at http://www.bis.gov.uk/assets/biscore/innovation/docs/i/11-1387-innovation-and-research-strategy-for-growth.pdf. Accessed 28 Nov 2013.
    • (2011) Innovation and Skills
  • 64
    • 85019228946 scopus 로고    scopus 로고
    • Cell therapy catapult
    • The Technology Strategy Board. (2013). Cell therapy catapult. Available at: https://ct.catapult.org.uk/home. Accessed 28 Nov 2013.
    • (2013) Available at:
  • 65
    • 85019228278 scopus 로고    scopus 로고
    • A strategy for UK regenerative medicine
    • Medical Research Council. (2012). A strategy for UK regenerative medicine. Available at http://www.mrc.ac.uk/Utilities/Documentrecord/index.htm?d=MRC008534. Accessed 28 Nov 2013.
    • (2012) Available at
  • 66
    • 85019252222 scopus 로고    scopus 로고
    • The Technology Strategy Board. (2013). Catapult progress update 2012–2013. Available at:. Accessed 13 Feb 2014.
    • The Technology Strategy Board. (2013). Catapult progress update 2012–2013. Available at: https://www.catapult.org.uk/documents/2155693/2268412/Catapult+Programme+Progress+update+2012-13/. Accessed 13 Feb 2014.
  • 67
    • 85019221339 scopus 로고    scopus 로고
    • About catapult
    • The Technology Strategy Board. (2013). About catapult. Available at: https://www.catapult.org.uk/work-with-us. Accessed 28 Nov 2013.
    • (2013) Available at:
  • 68
    • 85019175772 scopus 로고    scopus 로고
    • Accessibility, sustainability
    • Report of the Working Group on Expanding Access to Published Research Findings (Finch Group) (June 2012). Accessibility, sustainability, excellence: how to expand access to research publications.
    • (2012) excellence: how to expand access to research publications
  • 69
    • 85019244401 scopus 로고    scopus 로고
    • Government Response to the Finch Group Report: “Accessibility, sustainability
    • Department for Business, Innovation and Skills (BIS) (July 2012). Government Response to the Finch Group Report: “Accessibility, sustainability, excellence: how to expand access to research publications”.
    • (2012) excellence: how to expand access to research publications”
  • 70
    • 85019194627 scopus 로고    scopus 로고
    • Law 14/2007, of 3 July, on Biomedical Research.
    • Law 14/2007, of 3 July, on Biomedical Research.
  • 71
    • 85019243405 scopus 로고    scopus 로고
    • Law 22/2006 , of 26 May, on Assisted Reproductive Technology.
    • Law 22/2006, of 26 May, on Assisted Reproductive Technology.
  • 72
    • 85019216041 scopus 로고    scopus 로고
    • Consejo Superior de Investigaciones Cientificas. Presentación CSIC. Available at. Accessed 28 Nov 2013.
    • Consejo Superior de Investigaciones Cientificas. Presentación CSIC. Available at http://www.csic.es/web/guest/presentacion. Accessed 28 Nov 2013.
  • 73
    • 85019184875 scopus 로고    scopus 로고
    • Carlos III Health Institute. About Us. Available at. Accessed 28 Nov 2013.
    • Carlos III Health Institute. About Us. Available at http://www.eng.isciii.es/ISCIII/es/contenidos/fd-el-instituto/quienes-somos.shtml. Accessed 28 Nov 2013.
  • 74
    • 85019207948 scopus 로고    scopus 로고
    • Law No. 11/1986 of March 20, 1986 on Patents
    • Law No. 11/1986 of March 20, 1986 on Patents
  • 75
    • 85019231114 scopus 로고    scopus 로고
    • Law 14/2011, of 1 June, on Science, Technology and Innovation
    • Law 14/2011, of 1 June, on Science, Technology and Innovation
  • 76
    • 85019212341 scopus 로고    scopus 로고
    • Spanish National Cell Bank (SNCB), Material transfer agreement for transfer of materials to recipient scientists. SNCB, Valencia.
    • Spanish National Cell Bank (SNCB), Material transfer agreement for transfer of materials to recipient scientists. SNCB, Valencia.
  • 77
    • 85019221157 scopus 로고    scopus 로고
    • Furthermore, the central government repealed a law creating a federal regenerative medicine agency after Andalusia launched a constitutional challenge (Decision 534/2004
    • Science and health are shared competences in the Spanish federal order. The central government has exclusive jurisdiction over the coordination of scientific research and health (s. 149(1)(15), s. 149(1)(16), Spanish Constitution). Under this power, it coordinates human tissue procurement and can legislate on private umbilical tissue banks (Decision 22/2012, Constitutional Tribunal). The autonomous communities have residual jurisdiction over areas not attributed to the federal government, and explicit jurisdiction over the promotion of research (s. 149(3), s. 148(17) Spanish Constitution). Autonomous communities can thus legislate on specific scientific programs affecting health (Royal Decree 1825, 2009). Furthermore, the central government repealed a law creating a federal regenerative medicine agency after Andalusia launched a constitutional challenge (Decision 534/2004, Constitutional Tribunal).
    • (2009) Constitutional Tribunal)
  • 78
    • 85019247974 scopus 로고    scopus 로고
    • Oficina de Transferencia de Tecnología del SSPA (Andalucia Technology Transfer Office), Auerdo de Transferencia de Material. Available at. Accessed 28 Nov 2013.
    • Oficina de Transferencia de Tecnología del SSPA (Andalucia Technology Transfer Office), Auerdo de Transferencia de Material. Available at http://www.juntadeandalucia.es/ottforms/Acuerdo_Transferencia_Material.pdf. Accessed 28 Nov 2013.
  • 80
    • 85019250705 scopus 로고    scopus 로고
    • Andalusian Initiative for Advanced Therapies, Who We Are. Available at. Accessed 28 Nov 2013.
    • Andalusian Initiative for Advanced Therapies, Who We Are. Available at http://www.juntadeandalucia.es/terapiasavanzadas/en/home. Accessed 28 Nov 2013.
  • 81
    • 85019181812 scopus 로고    scopus 로고
    • Reference re Assisted Human Reproduction Act, 2010 (Canada) SCC 61, [2010] 3 SCR 457.
    • Reference re Assisted Human Reproduction Act, 2010 (Canada) SCC 61, [2010] 3 SCR 457.
  • 82
    • 85019232442 scopus 로고    scopus 로고
    • Updated guidelines for human pluripotent stem cell research
    • Canadian Institutes of Health Research. (2010). Updated guidelines for human pluripotent stem cell research. Available at http://www.cihr-irsc.gc.ca/e/42071.html. Accessed 28 Nov 2013.
    • (2010) Available at
  • 83
    • 84859517950 scopus 로고    scopus 로고
    • Ethical conduct for Research Involving Humans, Available at:
    • Canadian Institutes of Health Research. Natural Sciences and Engineering Research Council of Canada (NSERC), and Social Sciences and Humanities Research Council of Canada (SSHRC). (2010). Tri-council Policy Statement: Ethical conduct for Research Involving Humans. Available at http://www.ethics.gc.ca/pdf/eng/tcps2/TCPS_2_FINAL_Web.pdf. Accessed 28 Nov 2013.
    • (2010) Tri-council Policy Statement
  • 84
    • 85019178871 scopus 로고    scopus 로고
    • Canadian Institutes of Health Research Act, SC 2000, c 6.
    • Canadian Institutes of Health Research Act, SC 2000, c 6.
  • 85
    • 85019213563 scopus 로고    scopus 로고
    • Large-scale applied research project competition
    • Genome Canada. (2012). Large-scale applied research project competition. Available at http://www.genomecanada.ca/en/portfolio/research/2012-competition.aspx. Accessed 28 Nov 2013.
    • (2012) Available at
    • Canada, G.1
  • 86
    • 85019195989 scopus 로고    scopus 로고
    • ResearchNet, Transplantation Research. Available at. Accessed 28 Nov 2013.
    • ResearchNet, Transplantation Research. Available at https://www.researchnet-recherchenet.ca/rnr16/viewOpportunityDetails.do?progCd=10276&org=CIHR&language=E. Accessed 28 Nov 2013.
  • 87
    • 85019237255 scopus 로고    scopus 로고
    • ResearchNet, Team Grant: Canada-Japan CEEHRC Teams in Epigenetics of Stem Cells. Available at. Accessed 28 Nov 2013.
    • ResearchNet, Team Grant: Canada-Japan CEEHRC Teams in Epigenetics of Stem Cells. Available at https://www.researchnet-recherchenet.ca/rnr16/vwOpprtntyDtls.do?prog=1583&view=currentOpps&org=CIHR&type=AND&resultCount=25&sort=program&all=1&masterList=true. Accessed 28 Nov 2013.
  • 88
    • 85019200679 scopus 로고    scopus 로고
    • CIHR open access policy
    • Canadian Institutes of Health Research. (2013). CIHR open access policy. Available at http://www.cihr-irsc.gc.ca/e/32005.html. Accessed 28 Nov 2013.
    • (2013) Available at
  • 89
    • 85019232442 scopus 로고    scopus 로고
    • Updated guidelines for human pluripotent stem cell research
    • Canadian Institutes of Health Research (CIHR). (2010). Updated guidelines for human pluripotent stem cell research. Available at http://www.cihr-irsc.gc.ca/e/42071.html. Accessed 28 Nov 2013.
    • (2010) Available at
  • 90
    • 85019193366 scopus 로고    scopus 로고
    • Canada -Japan teams in epigenetics of stem cells grant criteria
    • Canadian Institutes of Health Research. (2012). Canada -Japan teams in epigenetics of stem cells grant criteria. Available at https://www.researchnet-recherchenet.ca/rnr16/vwOpprtntyDtls.do?prog=1583&view=currentOpps&org=CIHR&type=AND&resultCount=25&sort=program&all=1&masterList=true. Accessed 28 Nov 2013.
    • (2012) Available at
  • 91
    • 85019269098 scopus 로고    scopus 로고
    • CIHR program grant in transplantation research
    • Canadian Institutes of Health Research. (2012). CIHR program grant in transplantation research. Available at http://www.researchnet-recherchenet.ca/rnr16/vwOpprtntyDtls.do?prog=1463. Accessed 28 Nov 2013.
    • (2012) Available at
  • 92
    • 85019202869 scopus 로고    scopus 로고
    • Communication of Research Results
    • Canadian Institutes of Health Research. (2012). “Communication of Research Results” in Grants awards guide. Available at http://www.cihr-irsc.gc.ca/e/22631.html#2-A20-2. Accessed 28 Nov 2013.
    • (2012) in Grants awards guide
  • 93
    • 85019209574 scopus 로고    scopus 로고
    • Roles and Responsibilities, Available at:
    • Natural Sciences and Engineering Research Council of Canada. (2012). Responsibilities and Accountability: Roles and Responsibilities. Available at http://www.nserc-crsng.gc.ca/Professors-Professeurs/FinancialAdminGuide-GuideAdminFinancier/Responsibilities-Responsabilites_eng.asp. Accessed 28 Nov 2013.
    • (2012) Responsibilities and Accountability
  • 94
    • 85019174155 scopus 로고    scopus 로고
    • For example, a Transplantation Research Grant with a significant stem cell focus recommends that applicants list previous patents and intellectual property rights among their achievements, suggesting that commercialization potential is viewed positively and could increase the likelihood of receiving funds [91].
    • For example, a Transplantation Research Grant with a significant stem cell focus recommends that applicants list previous patents and intellectual property rights among their achievements, suggesting that commercialization potential is viewed positively and could increase the likelihood of receiving funds [91].
  • 95
    • 85019204306 scopus 로고    scopus 로고
    • Networks of centres of excellence: Research-driven partnerships: 16 networks of centres of excellence
    • Government of Canada. (2012). Networks of centres of excellence: Research-driven partnerships: 16 networks of centres of excellence. Available at http://www.nce-rce.gc.ca/NetworksCentres-CentresReseaux/NCE-RCE_eng.asp. Accessed 28 Nov 2013.
    • (2012) Available at
  • 96
    • 85019246625 scopus 로고    scopus 로고
    • Networks of centres of excellence overview
    • Government of Canada. (2011). Networks of centres of excellence overview. Available at http://www.nce-rce.gc.ca/ReportsPublications-RapportsPublications/NCE-RCE/ProgramGuide-GuideProgramme_eng.asp. Accessed 28 Nov 2013.
    • (2011) Available at
  • 97
    • 85019239889 scopus 로고    scopus 로고
    • About us
    • The Stem Cell Network. (2012). About us. Available at http://www.stemcellnetwork.ca/index.php?page=about-us&hl=eng. Accessed 28 Nov 2013.
    • (2012) Available at
    • Network, T.S.C.1
  • 98
    • 85019221756 scopus 로고    scopus 로고
    • Partners
    • The Stem Cell Network. (2012). Partners. Available at http://www.stemcellnetwork.ca/index.php?page=partners&hl=eng. Accessed 28 Nov 2013.
    • (2012) Available at
    • Network, T.S.C.1
  • 99
    • 85019192654 scopus 로고    scopus 로고
    • IP protection fund
    • The Stem Cell Network. (2012). IP protection fund. Available at http://www.stemcellnetwork.ca/index.php?page=ip-protection-fund&hl=eng. Accessed 28 Nov 2013.
    • (2012) Available at
    • Network, T.S.C.1
  • 100
    • 85019236447 scopus 로고    scopus 로고
    • Impact research
    • The Stem Cell Network. (2012). Impact research. Available at http://www.stemcellnetwork.ca/index.php?page=impact-research. Accessed 28 Nov 2013.
    • (2012) Available at
    • Network, T.S.C.1
  • 101
    • 85019176209 scopus 로고    scopus 로고
    • The Stem Cell Network. (2012). Available at. Accessed 28 Nov 2013.
    • The Stem Cell Network. (2012). http://www.stemcellnetwork.ca/uploads/funding-opportunities/DrugDiscoveryProgram_ApplicationGuidelines_Nov2013.pdf. Available at http://www.stemcellnetwork.ca/uploads/fundingopportunities/DrugDiscoveryProgram_ApplicationGuidelines_Aug-2012.pdf. Accessed 28 Nov 2013.
  • 102
    • 85019179788 scopus 로고    scopus 로고
    • The Stem Cell Network, Career Development. Available at. Accessed 28 Nov 2013.
    • The Stem Cell Network, Career Development. Available at http://www.stemcellnetwork.ca/index.php?page=career-development&hl=eng. Accessed 28 Nov 2013.
  • 103
    • 85019172633 scopus 로고    scopus 로고
    • IP toolkit
    • The Stem Cell Network. (2009). IP toolkit. Available at http://www.stemcellnetwork.ca/index.php?page=IP-Toolkit&hl=fra. Accessed 28 Nov 2013.
    • (2009) Available at
    • Network, T.S.C.1
  • 104
    • 85019216880 scopus 로고    scopus 로고
    • Stem Cell Network. License Agreement template. Available at. Accessed 28 Nov 2013.
    • Stem Cell Network. License Agreement template. Available at http://www.stemcellnetwork.ca/uploads/File/resources/template-License-Agreement-eng.pdf. Accessed 28 Nov 2013.
  • 105
    • 85019259738 scopus 로고    scopus 로고
    • Canada: Capitalizing in a 50-year legacy. In C. Prescott & J. Polak (Eds.), The delivery of regenerative medicines and their impact on healthcare (pp
    • Boca Raton: CRC Press
    • Lyall, A. (2010). Canada: Capitalizing in a 50-year legacy. In C. Prescott & J. Polak (Eds.), The delivery of regenerative medicines and their impact on healthcare (pp. 43–58). Boca Raton: CRC Press.
    • (2010) 43–58)
    • Lyall, A.1
  • 106
    • 85019178537 scopus 로고    scopus 로고
    • Down the rabbit hole: technology transfer in the field of stem cell research
    • Joly, Y., Pham, C., Schorno, D., & Knoppers, B. M. (2008). Down the rabbit hole: technology transfer in the field of stem cell research. Revista da Faculdade de Direito UFPR, 47, 101–140.
    • (2008) Revista da Faculdade de Direito UFPR , vol.47 , pp. 101-140
    • Joly, Y.1    Pham, C.2    Schorno, D.3    Knoppers, B.M.4
  • 107
    • 85019262601 scopus 로고    scopus 로고
    • Welcome
    • Centre for Commercialization of Regenerative Medicine. (2011). Welcome. Available at: http://www.ccrm.ca/. Accessed 28 Nov 2013.
    • (2011) Available at:
  • 108
    • 85019263515 scopus 로고    scopus 로고
    • This Act does not affect SCR using induced pluripotent stem cells (iPSCs, Unlike human embryonic stem cells (hESCs), iPSCs are derived from adult cells and do not imply the destruction of embryos:
    • Omnibus Appropriations Act, 2009, s. 509; This Act does not affect SCR using induced pluripotent stem cells (iPSCs). Unlike human embryonic stem cells (hESCs), iPSCs are derived from adult cells and do not imply the destruction of embryos.
    • (2009) s. 509
    • Act, O.A.1
  • 109
    • 85019207762 scopus 로고    scopus 로고
    • National Institutes of Health Guidelines for Human Stem Cell Research
    • National Institutes of Health (2009). National Institutes of Health Guidelines for Human Stem Cell Research. Available at: http://stemcells.nih.gov/policy/pages/2009guidelines.aspx. Accessed 28 Nov 2013.
    • (2009) Available at:
  • 111
    • 84858274058 scopus 로고    scopus 로고
    • The NIH and the regenerative medicine field
    • Mahendra, R. (2011). The NIH and the regenerative medicine field. Regenerative Medicine, 7(2), 129–131.
    • (2011) Regenerative Medicine , vol.7 , Issue.2 , pp. 129-131
    • Mahendra, R.1
  • 112
    • 85019245920 scopus 로고    scopus 로고
    • This proportion of outsourced research includes all research topics.
    • This proportion of outsourced research includes all research topics.
  • 113
    • 85019210571 scopus 로고    scopus 로고
    • Principles and guidelines for recipients of NIH research grants and contracts on obtaining and disseminating biomedical research resources
    • National Institutes of Health. (1999). Principles and guidelines for recipients of NIH research grants and contracts on obtaining and disseminating biomedical research resources. Available at http://www.ott.nih.gov/policy/rt_guide_final.html#1. Accessed 28 Nov 2013.
    • (1999) Available at
  • 114
    • 85019175804 scopus 로고    scopus 로고
    • NIH policy on sharing of model organisms for biomedical research
    • National Institutes of Health (2004). NIH policy on sharing of model organisms for biomedical research. Available at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-04-042.html. Accessed 28 Nov 2013.
    • (2004) Available at
  • 115
    • 84892635990 scopus 로고    scopus 로고
    • Department of Health and Human Services. Best practices for the licensing of genomic inventions, Final notice:
    • National Institutes of Health. Public Health Service. (2005). Department of Health and Human Services. Best practices for the licensing of genomic inventions: Final notice. Available at http://www.ott.nih.gov/policy/lic_gen.html. Accessed 28 Nov 2013.
    • (2005) Public Health Service
  • 116
    • 85019193007 scopus 로고    scopus 로고
    • NIH data sharing policy and implementation guidance
    • National Institutes of Health. (2003). NIH data sharing policy and implementation guidance. Available at http://www.ott.nih.gov/policy/rt_guide_final.html. Accessed 28 Nov 2013.
    • (2003) Available at
  • 117
    • 85019237497 scopus 로고    scopus 로고
    • National Institutes of Health. NIH Data Sharing Policies. Available at. Accessed 28 Nov 2013.
    • National Institutes of Health. NIH Data Sharing Policies. Available at http://www.nlm.nih.gov/NIHbmic/nih_data_sharing_policies.html. Accessed 28 Nov 2013.
  • 118
    • 85019179302 scopus 로고    scopus 로고
    • National Institute of Allergy and Infectious Diseases. Data Sharing Guiding Principles for the NIAID/DMID Systems Biology Program.Section 7. Available at. Accessed 28 Nov 2013.
    • National Institute of Allergy and Infectious Diseases. Data Sharing Guiding Principles for the NIAID/DMID Systems Biology Program.Section 7. Available at http://www.niaid.nih.gov/labsandresources/resources/dmid/sb/pages/datareleaseguidelines.aspx. Accessed 28 Nov 2013.
  • 119
    • 85019256600 scopus 로고    scopus 로고
    • WiCell Research Institute. Material transfer agreement for non-profit recipients. Available at. Accessed 28 Nov 2013.
    • WiCell Research Institute. Material transfer agreement for non-profit recipients. Available at http://www.wicell.org/media/WiCellAgreements/WiCell-iPS-MTA.pdf. Accessed 28 Nov 2013.
  • 120
    • 85019224682 scopus 로고    scopus 로고
    • Wisconsin International Stem Cell (WISC) Bank. Memorandum of understanding – WiCell cGMP. Available at. Accessed 28 Nov 2013.
    • Wisconsin International Stem Cell (WISC) Bank. Memorandum of understanding – WiCell cGMP. Available at http://www.wicell.org/media/WiCellAgreements/WiCell-Matched-Research-Bank-Materials-MOU-SLA.pdf. Accessed 28 Nov 2013.
  • 121
    • 85019170589 scopus 로고    scopus 로고
    • Wisconsin International Stem Cell (WISC) Bank. Memorandum of Understanding –Wisconsin Materials. Available at. Accessed 28 Nov 2013.
    • Wisconsin International Stem Cell (WISC) Bank. Memorandum of Understanding –Wisconsin Materials. Available at http://www.wicell.org/media/WiCellAgreements/Wisconsin-Materials-Buck-Materials.pdf. Accessed 28 Nov 2013.
  • 122
    • 85019229610 scopus 로고    scopus 로고
    • California Stem Cell Research and Cures Bond Act of 2004, CAL. HEALTH & SAFETY CODE § 125291.30 (West 2004).
    • California Stem Cell Research and Cures Bond Act of 2004, CAL. HEALTH & SAFETY CODE § 125291.30 (West 2004).
  • 123
    • 85019234531 scopus 로고    scopus 로고
    • California Institute of Regenerative Medicine. Frequently asked questions. Available at. Accessed 28 Nov 2013.
    • California Institute of Regenerative Medicine. Frequently asked questions. Available at http://www.cirm.ca.gov/about-cirm/cirm-faq. Accessed 28 Nov 2013.
  • 124
    • 77149140111 scopus 로고    scopus 로고
    • The California stem cell initiative: persuasion, politics and public science
    • PID: 20075315
    • Adelson, J. W., & Weinberg, J. K. (2010). The California stem cell initiative: persuasion, politics and public science. American Journal of Public Health, 100(3), 446–451.
    • (2010) American Journal of Public Health , vol.100 , Issue.3 , pp. 446-451
    • Adelson, J.W.1    Weinberg, J.K.2
  • 125
    • 85019255776 scopus 로고    scopus 로고
    • California Code of Regulations, (Vol. 22), Title 17, Public Health.
    • California Code of Regulations, (Vol. 22), Title 17, Public Health.
  • 126
    • 85028083935 scopus 로고    scopus 로고
    • Leading the entrepreneurial university: Meeting the entrepreneurial development needs of higher education institutions. In: Universities in Change (pp. 9–45)
    • Gibb, A., Haskins, G., & Robertson, I. (2013). Leading the entrepreneurial university: Meeting the entrepreneurial development needs of higher education institutions. In: Universities in Change (pp. 9–45). Springer New York.
    • (2013) Springer New York
    • Gibb, A.1    Haskins, G.2    Robertson, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.